A rare case of lung carcinoma with mucoepidermoid histopathology: a case report and review of the literature.

Abstract:

:Mucoepidermoid carcinoma of the lung is exceedingly rare. Our case involves a 58-year-old male who presented with shortness of breath, dysphagia, and weight loss. He denied ever smoking. Chest x-ray revealed trapped lung, and CT demonstrated a right bronchial mass. Diagnosis of lung carcinoma was made by bronchoscopic FNA biopsy. EGFR mutation was negative. Staging workup demonstrated evidence of advanced disease. Performance status was good, and it was decided to start chemotherapy and radiation for palliation. Lung carcinomas often present as an obstructing hilar mass. There are different histological grades that affect progression and survival. Though uncommon, metastatic spread has been previously reported. Studies have investigated the possible role of tyrosine kinase inhibitors in both EGFR-mutated and non-mutated cases. Unfortunately, there has been little consensus as to which therapies are most beneficial.

journal_name

Ann Clin Lab Sci

authors

Thomas D,Modi Y,Dorai B,Guron G

subject

Has Abstract

pub_date

2015-04-01 00:00:00

pages

219-21

issue

2

eissn

0091-7370

issn

1550-8080

pii

45/2/219

journal_volume

45

pub_type

杂志文章,评审
  • Mechanisms of Resistance in Clinical Isolates of Enterobacter cloacae that Are Less Susceptible to Cefepime than to Ceftazidime.

    abstract::Thirty-two Enterobacter cloacae strains that are less susceptible to cefepime than to ceftazidime were collected. This unique phenotype of 8 strains was confirmed using the agar dilution method. OXA1, OXA10, OXA31 and OXA35 were detected in 3, 2, 3, and 2 strains, respectively, whereas all strains were negative for PS...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Liu L,Yu J,Tang M,Liu J

    更新日期:2018-05-01 00:00:00

  • Strategic utilization of cardiac markers for the diagnosis of acute myocardial infarction.

    abstract::Current changes of the healthcare environment have promoted the creation of chest pain centers in the emergency departments for rapid triage of patients admitted for cardiac evaluation. Because of the inefficiency of electrocardiogram for the diagnosis of acute myocardial infarction, blood cardiac markers play an impo...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Wong SS

    更新日期:1996-07-01 00:00:00

  • Point-of-care testing for drugs of abuse in an urban emergency department.

    abstract::Point-of-care testing (POCT) has been used for illicit substance screening in several settings, primarily in law enforcement and drug treatment centers. In this study, we evaluate the use of this screening approach in the emergency department (ED) of a tertiary-care, urban medical center. Aliquots of urine specimens w...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Mastrovitch TA,Bithoney WG,DeBari VA,Nina AG

    更新日期:2002-10-01 00:00:00

  • Intravascular large B-cell lymphoma presenting as cholecystitis and pancytopenia: case report with literature review.

    abstract::Intravascular large B-cell lymphoma (IVLBCL) is a rare variant of extranodal diffuse large Bcell lymphoma with only a few more than 300 cases reported. It is characterized as lymphoma cells confined to the lumina of small vessels, so patients usually do not present with masses or lymphadenopathy. Clinical presentation...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章,评审

    doi:

    authors: Duan X,Lapus A,Brown RE,Chen L

    更新日期:2011-07-01 00:00:00

  • Humoral and Cellular Immunity Changed after Traumatic Brain Injury in Human Patients.

    abstract::Previous studies have suggested that there is a disproportionally higher risk of infection following traumatic brain injury (TBI). This predisposition to infection may be driven by a poorly understood, brain-specific response in the immune system after TBI. However, there is a lack of studies that have fully character...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Wang JW,Li JP,Song YL,Zhao QH

    更新日期:2017-01-01 00:00:00

  • Progression of renal damage in the obese Zucker rat in response to deoxycorticosterone acetate-salt-induced hypertension.

    abstract::This study assessed the progression of renal damage in obese Zucker rats in response to deoxycorticosterone acetate (DOCA)-salt-induced hypertension. Renal damage was evaluated by light microscopy and urine analysis at weekly intervals during the developmental phase of DOCA-salt hypertension and once during the platea...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Morrison RG,Carpenter AB,Adams VL,Mangiarua EI,Wehner PS,McCumbee WD

    更新日期:2005-01-01 00:00:00

  • In vitro production of monoclonal human rheumatoid factors.

    abstract::Lymphocytes from rheumatoid arthritis patients have been fused with drug-marked human myeloma cell lines and hybrids selected which secrete rheumatoid factors. Limiting dilution and soft agarose plates have been used to clone these hybrids, but so far stable clones have not been obtained. Epstein-Barr virus has been u...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Normansell DE,Lane JR

    更新日期:1984-01-01 00:00:00

  • Acute non-lymphocytic leukemia in a lymph node concurrent with Hodgkin's lymphoma.

    abstract::A case of a 40 year-old woman with Hodgkin's disease who developed acute non-lymphocytic leukemia (ANLL) accompanied by several abnormal chromosomal findings is illustrated. A very unusual coincidental finding was the coexistence of Hodgkin's lymphoma and ANLL in the same lymph node. ...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Silberman S,Messmore HL Jr

    更新日期:1985-01-01 00:00:00

  • Vitamin K deficiency bleeding leading to the diagnosis of Crohn's disease.

    abstract::We report the case of a 45 year old man who came to Emergency Room of Polyclinic for sudden onset of localized ecchymosis and widespread hematomas. He was subjected to blood count and first level investigations to assess coagulation. Based on the results, second level investigations were performed. Endoscopy of the ga...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Agnello L,Bellia C,Lo Coco L,Vitale S,Coraci F,Bonura F,Gnoffo R,Napolitano M,Caruso A,Bivona G,Lo Sasso B,Ciaccio M

    更新日期:2014-07-01 00:00:00

  • Review of risk factors for cardiovascular diseases.

    abstract::Traditional risk factors for coronary heart disease (CHD) include only the patient's age and family history and whether there is evidence of hypertension, elevated LDL, low HDL, diabetes or history of smoking. In recent years, considerable progress has been made in identifying a new generation of risk factors, includi...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章,评审

    doi:

    authors: Wu LL

    更新日期:1999-04-01 00:00:00

  • Comparison of M4 and M4RT media for transporting cervical swab samples for PCR detection of Chlamydia trachomatis and Neisseria gonorrhoeae.

    abstract::In a prospective study, M4RT medium was compared to the traditional M4 medium to transport cervical swab specimens for Neisseria gonorrhoeae/Chlamydia trachomatis (NG/CT) PCR testing using the Roche COBAS Amplicor. Two cervical swab samples were collected from 270 consecutive patients screened for NG/CT in a satellite...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Aslanzadeh J,Jones M

    更新日期:2002-01-01 00:00:00

  • Non-anion gap acidosis in asthma: clinical and laboratory features and outcomes for hospitalized patients.

    abstract::Metabolic acidosis secondary to lactic acidosis may occur in acute, severe asthma and its presence suggests that respiratory muscle fatigue and tissue hypoxia play a major part in the pathogenesis. Non-anion gap metabolic acidosis (NAG acidosis) has also been reported in acute asthma but its impact on the clinical out...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Rashid AO,Azam HM,DeBari VA,Blamoun AI,Moammar MQ,Khan MA

    更新日期:2008-07-01 00:00:00

  • Glucose-6-phosphate dehydrogenase in vitro correlated with in vivo activity and reticulocytosis.

    abstract::In vitro activity of erythrocyte glucose-6-phosphate dehydrogenase (G-6-PD) does not always correlate with in vivo hemolytic manifestations. Many of these non-correlations are reviewed and can now be explained on the basis of altered substrate affinity and/or altered inhibition by intracellular metabolites. These alte...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Brewster MA,Quittner H,Moriarity M

    更新日期:1977-07-01 00:00:00

  • Thiosulfate-citrate-bile salts-sucrose agar and its selectivity for clinical and marine vibrio organisms.

    abstract::Recently documented Vibrio cholerae and non-cholera vibrio infections in Florida and other American waters led to a study to determine the selectivity of thiosulfate-citrate-bile salts-sucrose media (TCBS). Thirty-one species with 188 different strains of clinical, marine, and stock origin were examined on the TCBS me...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Lotz MJ,Tamplin ML,Rodrick GE

    更新日期:1983-01-01 00:00:00

  • Immunologic effects of gliotoxin in rats: mechanisms for prevention of autoimmune diabetes mellitus.

    abstract::Various fungal products, such as gliotoxin (GT), have immunomodulating activity, a fact exploited previously by our group for prevention of autoimmune diabetes mellitus in BB/Wor rats. To understand better the immunologic effects in GT-treated rats, splenocytes from 65-day-old prediabetic diabetes-prone rats were phen...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Liu H,Jackman S,Driscoll H,Larsen B

    更新日期:2000-10-01 00:00:00

  • Discordant results of CK-MB and troponin I measurements: a review of 14 cases.

    abstract::In the course of a clinical comparison involving 204 parallel total creatine kinase (CK), creatine kinase-MB isoenzyme (CK-MB), and cardiac troponin I (cTnI) measurements, 12 patients were identified in whom cTnI was elevated while total CK was normal, as well as 2 patients in whom CK-MB was elevated while cTnI was no...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Bennett AE,Bertholf RL

    更新日期:2000-04-01 00:00:00

  • Higher sensitivity of capillary electrophoresis in detecting hemoglobin A2'compared to traditional gel electrophoresis.

    abstract::HbA2' (also called Hb B2) is the most common delta-globin chain defect and is reported to occur in 1-2% of the African American population. The major clinical significance of HbA2' is that the failure to detect it might lead to an underestimation of the total HbA2, leading to failure to diagnose β-thalassemia minor. I...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Oleske DA,Huang RS,Dasgupta A,Nguyen A,Wahed A

    更新日期:2014-07-01 00:00:00

  • Recurrent adenocarcinoma of the fallopian tube presenting as leptomeningeal carcinomatosis.

    abstract::Primary adenocarcinoma of the fallopian tube is a rare malignant neoplasm of the female reproductive system. Unusual patterns of metastasis may be observed. Report is made of a patient with recurrent adenocarcinoma of the fallopian tube, which presented as leptomeningeal carcinomatosis, as a first site of distant meta...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Vadmal MS,Brones C,Farmer PM

    更新日期:1996-03-01 00:00:00

  • MIF-like activity in non-stimulated and virus infected cell cultures.

    abstract::Macrophage-migration inhibition factor (MIF) is a lymphocyte-derived substance which plays an important role in cell mediated immunity. Soluble factors containing MIF-like activity and produced by non-stimulated and virus-infected non-lymphoid cell cultures have also been reported. In the present study, a MIF-like fac...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Brown EW,Burdash NM,Manos JP,Duncan RC

    更新日期:1978-09-01 00:00:00

  • Wellness assessment: A role for laboratory medicine.

    abstract::Within the next 20-25 years, 20% of the U.S. population is expected to be 65 years old or older. Unless significant changes are made (ie, increased research, improved treatment, and promotion of health and disease prevention), medical costs will continue to rise but with fewer citizens to finance them. However, this n...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章,评审

    doi:

    authors: Knight JA

    更新日期:2000-01-01 00:00:00

  • Effect of experimental hyperhomocysteinemia on cardiac structure and function in the rat.

    abstract::Male Sprague-Dawley rats were subjected for 2 weeks to daily injections of homocysteine (Hcy), which increased plasma Hcy approximately 2-fold. Echocardiography indicated significant increases in left ventricular diastolic (13%) and systolic (31%) dimensions and decreases in posterior wall thickness (diastolic, -17%; ...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Walker E,Black J,Parris C,Bryda EC,Cansino S,Hunt L,Chappell J,Wehner P,Studeny M,Wright GL

    更新日期:2004-04-01 00:00:00

  • Thymic Carcinoid as the First Manifestation of Multiple Endocrine Neoplasia Type 1 Syndrome: A Case Report and Review of the Literature.

    abstract::The present study reported a rare case with thymic carcinoid as the first manifestation of multiple endocrine neoplasia type 1 (MEN1) syndrome, which presented with gene mutations of the MEN1 and glucokinase regulatory protein (GCKR). In this report, a 40-year-old male was diagnosed as MEN1 syndrome with thymic carcin...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Zheng M,Chen S,Qi C,Ren L,Zhen Y,Yu X,Wei L

    更新日期:2020-11-01 00:00:00

  • Lipid peroxidation in platelet concentrates: effects of leukocyte removal by filtration.

    abstract::Increased lipid peroxidation (LP) occurs in the presence of various transition, metal ions, including copper and iron, as well as various heme moieties. In addition, irradiation significantly increases LP. The degree of LP, as determined by the liquid chromatographic measurement of plasma malondialdehyde (MDA), can be...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Knight JA,Searles DA,Blaylock RC

    更新日期:1994-01-01 00:00:00

  • Do Muscle Enzyme Changes Forecast Liver Injury in Polymyositis/Dermatomyositis Patients Treated with Methylprednisolone and Methotrexate?

    abstract:BACKGROUND:Long-term use of hormones and immunosuppressive agents is necessary for treating polymyositis (PM)/dermatomyositis (DM) but may cause liver damage. At what point do the costs of treatment outweigh the benefits, and how will the breakeven point be determined? METHODS:Serum muscle enzyme changes in 93 PM/DM p...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Shi Q,Niu J,Huang X,Pu C

    更新日期:2016-05-01 00:00:00

  • Cytologic diagnosis of multiple myeloma and macroglobulinemia in effusions.

    abstract::The presence of effusion in association with multiple myeloma or macroglobulinemia is an unusual finding which generally occurs late in the course of the disease. Occasionally, cytoligic detection is a diagnostic problem. In both conditions, the fluid is characrerized by a high specific gravity and high protein conten...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Gondos B,Miller TR,King EB

    更新日期:1978-01-01 00:00:00

  • Cryopreservation of Genotyped ABO Subgroup RBCs for Quality Assurance of ABO Grouping Reagents.

    abstract:BACKGROUND:Quality assurance of newly developed or manufactured blood grouping reagents with reagent red blood cells (RBCs) is crucial in the process of product approval by governmental agency. However, RBCs with rare blood group are not easily available in the fresh state. We investigated the feasibility of cryopreser...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Kim S,Song S,Kim HO

    更新日期:2018-03-01 00:00:00

  • Ultrastructure of the liver and biliary tract in health and disease.

    abstract::Ultrastructural studies with the transmission (TEM) and scanning (SEM) electron microscopes have added greatly to our knowledge of cellular structure and function in the liver. The normal polyhedral hepatocyte has numerous subcellular organelles, such as mitochondria, peroxisomes, lysosomes and complex rough (rer) and...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章,评审

    doi:

    authors: Goldblatt PJ,Gunning WT 3rd

    更新日期:1984-03-01 00:00:00

  • Possible Implication of GSTP1 and NQO1 Polymorphisms on Natalizumab Response in Multiple Sclerosis.

    abstract::Oxidative stress plays a pivotal role in the pathogenesis of multiple sclerosis (MS). Inactivating polymorphism of genes encoding detoxification enzymes, such as NQO1 and GSTP1 could influence susceptibility to MS. The monoclonal antibody natalizumab is an effective treatment in MS. Natalizumab's efficacy in MS patien...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Alexoudi A,Zachaki S,Stavropoulou C,Gavrili S,Spiliopoulou C,Papadodima S,Karageorgiou CE,Sambani C

    更新日期:2016-12-01 00:00:00

  • Hyperglycemic macrocytosis in electronically determined mean corpuscular volume. Use of three different automatic cell counters.

    abstract::Spurious macrocytosis in electronic cell counters has been associated with hyperglycemia. The increased mean corpuscular volume (MCV) is thought to be secondary to osmotic disequilibrium between the erythrocyte and the diluent used in the automatic cell counters. Employing three different hematology cell counters, the...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Planas AT,Van Voolen GA,Kelly LA

    更新日期:1985-07-01 00:00:00

  • Pulmonary gas exchange during hemodialysis: a comparison of subjects with and without COPD on bicarbonate hemodialysis.

    abstract::Little is known about the effect of hemodialysis (HD) on gas exchange in subjects with chronic obstructive pulmonary disease (COPD). The purpose of this study was to examine blood gases and pH in COPD patients undergoing HD with bicarbonate dialysate. We studied thirteen subjects with COPD and thirteen controls (CON)....

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Alfakir M,Moammar MQ,Ali MI,Alhatem E,Curran RD,Saoud RM,Chandran C,Khan MA,Debari VA

    更新日期:2011-10-01 00:00:00