Glucose and Fat Metabolism in Acromegaly: From Mice Models to Patient Care.

abstract：:The neurotransmitter and andrenoceptors involved in the inhibition of luteinizing hormone (LH) release induced by stimulating the locus ceruleus nucleus (LC) have been characterized in ovariectomized, estrogen-primed rats in which the release of LH was triggered by electrical stimulation of the medial preoptic area. B...

journal_title：Neuroendocrinology

authors： Dotti C,Taleisnik S

更新日期：1984-01-01 00:00:00

abstract：:When fetal preoptic area (POA) brain grafts that contain gonadotropin-releasing hormone cells are transplanted into the third ventricle of adult female hypogonadal mice, the animals respond with sexual maturation, persistent estrus, and the ability to ovulate reflexively after mating. However, the absence of normal sp...

journal_title：Neuroendocrinology

authors： Gibson MJ,Kokoris GJ,Silverman AJ

更新日期：1988-08-01 00:00:00

abstract：:We have investigated the hypothesis that administration of progesterone to estrogen-treated ovariectomized (OVX) rats enhances the stimulatory effects of neuropeptide Y (NPY) on the secretion of luteinizing hormone-releasing hormone (LHRH) from median eminence (ME) fragments in vitro. Adult rats were bilaterally OVX a...

journal_title：Neuroendocrinology

authors： Sabatino FD,Collins P,McDonald JK

更新日期：1990-12-01 00:00:00

abstract：:The effect of steroids on the two gonadotropin-releasing hormone (GnRH) forms present in the eel (mammalian GnRH, mGnRH and chicken GnRH-II, cGnRH-II), as well as on gonadotropin (GTH), was studied using specific radioimmunoassays. Female silver eels received chronic treatments with various steroids (estradiol, testos...

journal_title：Neuroendocrinology

authors： Montero M,Le Belle N,King JA,Millar RP,Dufour S

更新日期：1995-05-01 00:00:00

abstract：:The effects of hepatic vagotomy upon the circadian rhythm of lipogenesis and body fat store levels were tested in seasonally obese Syrian hamsters. Lipogenesis was studied 8 weeks after surgery by measuring the incorporation of label into epididymal and retroperitoneal fat pad lipid in animals killed 30 min after intr...

journal_title：Neuroendocrinology

authors： Martin DD,Cincotta AH,Meier AH

更新日期：1990-07-01 00:00:00

abstract：:Gastric carcinoids are rare neuroendocrine tumors, usually classified as type I, if associated with atrophic body gastritis; type II, if associated with Zollinger-Ellison syndrome and multiple endocrine neoplasia type I, and type III, in the absence of any gastric pathology (sporadic tumors). The pathological features...

journal_title：Neuroendocrinology

authors： Delle Fave G,Capurso G,Annibale B,Panzuto F

更新日期：2004-01-01 00:00:00

abstract：:Previous work in many laboratories has shown that luteinizing hormone-releasing hormone (LHRH) neurons display a range of shapes from smooth-contoured to extremely irregular or 'thorny'. To determine if these forms reflect or can be modified by the gonadal steroid milieu, the morphology of LHRH neurons was examined in...

journal_title：Neuroendocrinology

authors： Witkin JW

更新日期：1989-04-01 00:00:00

abstract：:Methanol extracts of rat plasma resulted in release of prolactin (PRL) from rat hemipituitaries in vitro with a linear log-dose relationship. This prolactin-releasing factor (PRF)-like activity was not altered in plasma from rats treated with bromocryptine or chlorpromazine despite significant suppression and stimulat...

journal_title：Neuroendocrinology

authors： Garthwaite TL,Hagen TC

更新日期：1979-01-01 00:00:00

abstract：:We have previously shown that the serotonergic regulation of renin secretion from the kidneys is mediated by a renin-releasing factor (RRF) that is present in both plasma and hypothalamus. The present studies were designed to determine the distribution of RRF in the brain and peripheral tissues and to test whether RRF...

journal_title：Neuroendocrinology

authors： Urban JH,Brownfield MS,Levine JE,Van de Kar LD

更新日期：1992-05-01 00:00:00

abstract：:Recordings were made of single unit activity through chronically implanted electrodes within the hypothalamic paraventricular nucleus of freely moving male rats also bearing chronically implanted stimulating electrodes in the preoptic area (POA) and indwelling jugular cannulae. High frequency electrical stimulation of...

journal_title：Neuroendocrinology

authors： Saphier D,Feldman S

更新日期：1986-01-01 00:00:00

abstract：:Gastroenteropancreatic (GEP) endocrine tumors are hypervascular tumors able to synthesize and secrete high amounts of VEGF. We aimed to study the regulation of VEGF production in GEP endocrine tumors and to test whether some of the drugs currently used in their treatment, such as somatostatin analogues and mTOR inhibi...

journal_title：Neuroendocrinology

authors： Villaume K,Blanc M,Gouysse G,Walter T,Couderc C,Nejjari M,Vercherat C,Cordier-Bussat M,Roche C,Scoazec JY

更新日期：2010-01-01 00:00:00

abstract：:Both the pituitary-adrenal axis and the pituitary-gonadal axis are under the tonic inhibitory control of endogenous opioid peptides in man. However, the precise opioid receptor involved in the modulation of these hormones remains unknown. The effect of a dose of intravenous naloxone on serum levels of luteinising horm...

journal_title：Neuroendocrinology

authors： Grossman A,Moult PJ,Cunnah D,Besser M

更新日期：1986-01-01 00:00:00

abstract：:To assess the neuroendocrine correlates of menstrual status migrainosus (MSM) and menstrual migraine (MM), we evaluated the prolactin (PRL) and cortisol responses to the direct central serotoninergic (5-HT) agonist meta-chlorophenylpiperazine (m-CPP) administered orally (0.5 mg/kg) during the follicular (FP: +6, +8) a...

journal_title：Neuroendocrinology

authors： Nappi RE,Sances G,Brundu B,Ghiotto N,Detaddei S,Biancardi C,Polatti F,Nappi G

更新日期：2003-07-01 00:00:00

abstract：:It has been well documented that interleukin-1beta (IL-1beta) is a major mediator for recruiting the hypothalamo-pituitary-adrenal (HPA) axis following infectious disease. The recent localization of IL-1beta receptors in neurons of the hippocampus provides further support for the role of IL-1beta as a neurotransmitter...

journal_title：Neuroendocrinology

authors： Mélik Parsadaniantz S,Daugé V,Roques BP,Kerdelhué B

更新日期：1999-02-01 00:00:00

abstract：:The effect of amphetamine (AMPH) on plasma corticosterone was studied in the conscious, unstressed rat. AMPH (0.5-5.0 mg/kg) produced a dose-dependent increase in plasma corticosterone. This rise in plasma corticosterone was not altered by the adrenergic blocking agents phenoxybenzamine or propranolol. In contrast, th...

journal_title：Neuroendocrinology

authors： Knych ET,Eisenberg RM

更新日期：1979-01-01 00:00:00

abstract：:It is now well documented that various polyclonal antisera to the human growth hormone-releasing factor (hGHRF, somatocrinin) visualize in the brain by immunohistochemistry the classical hypothalamic hypophysiotropic neurons and also antigens present in otherwise characterized peptidergic neuronal systems. The nature ...

journal_title：Neuroendocrinology

authors： Ciofi P,Tramu G,Bloch B

更新日期：1990-04-01 00:00:00

abstract：:A portion of medial basal hypothalamus containing the supraoptic nuclei with the neurohypophysis attached was organ cultured. Hypothalamus and neurohypophysis were maintained in separate compartments, and the intact infundibular stalk passed through a hole in a fluid-tight barrier which separated the two compartments....

journal_title：Neuroendocrinology

authors： Gregg CM

更新日期：1985-05-01 00:00:00

abstract：:We report the development of a radioimmunoassay for prepro-TRH(160-169) (PS4), a thyrotropin-releasing hormone (TRH) enhancing peptide, and its use in characterizing the effect of electroconvulsive seizures on the levels of this peptide in various brain regions of male Wistar rats. We found that electroconvulsive seiz...

journal_title：Neuroendocrinology

authors： Pekary AE,Sattin A,Lloyd RL

更新日期：1997-05-01 00:00:00

abstract：:The level of thyroid hormone in blood has been acutely decreased by about 20--30% within 20 min with the aid of isovolemic exchange transfusion (IET) of thyroid hormone free blood cell suspension (THFBCS) in three groups of rats: (1) intact control (C); (2) median eminence (ME)-lesioned; (3) thalamus (TH)-lesioned. Th...

journal_title：Neuroendocrinology

authors： Langer P,Földes O,Mess B,Kokesová H,Gschwendtová K

更新日期：1977-01-01 00:00:00

abstract：:Characteristic increases in neuronal activity coincident with the pulsatile release of luteinizing hormone from the pituitary gland have been recorded from electrodes chronically implanted in the medial basal hypothalamus of the rhesus monkey. This electrophysiologic manifestation of the hypothalamic 'pulse generator'...

journal_title：Neuroendocrinology

authors： Wilson RC,Kesner JS,Kaufman JM,Uemura T,Akema T,Knobil E

更新日期：1984-09-01 00:00:00

abstract：:The incidence of obesity is rapidly escalating and has reached epidemic proportions. In all species, including rodents, humans, and sheep, there is large variation in the degree of weight gain across individuals in response to an obesogenic environment. This individual variation is, at least in part, determined by inn...

journal_title：Neuroendocrinology

authors： Henry BA

更新日期：2017-01-01 00:00:00

abstract：:The hypothesis was tested that corticotropin-releasing factor (CRF) is involved in the inhibition of gonadotropin secretion during chronic hyperprolactinemia. Two models of hyperprolactinemia were used, namely inoculation with the prolactin (PRL)-secreting tumor 7315b and implantation of isogenic pituitary glands. Gon...

journal_title：Neuroendocrinology

authors： Kooy A,de Greef WJ,Vreeburg JT,Hackeng WH,Ooms MP,Lamberts SW,Weber RF

更新日期：1990-03-01 00:00:00

abstract：:Previous studies indicate that 7 days after testicular administration of naloxone, serum testosterone (T) concentration and basal T secretion in vitro decrease significantly. In neonatal rats, short-term (2 h) intratesticular treatment with 0.3 micrograms (D-Met2-Pro5)-enkephalinamide suppresses steroidogenesis. In th...

journal_title：Neuroendocrinology

authors： Gerendai I,Nemeskéri A,Csernus V

更新日期：1992-09-01 00:00:00

abstract：:His-dTrp-Ala-Trp-dPhe,Lys-NH2(GHRP-6) is a synthetic compound that releases GH in a dose-response and specific manner in several species and that may well be related to an endogenous compound of similar structure. The aim of this study was to investigate the in vivo GH responses to GHRP-6 in pentobarbital anesthetized...

journal_title：Neuroendocrinology

authors： Mallo F,Alvarez CV,Benitez L,Burguera B,Coya R,Casanueva FF,Dieguez C

更新日期：1993-01-01 00:00:00

abstract：INTRODUCTION:An increasing number of middle-aged men are being screened for low testosterone levels and the number of prescriptions for various forms of testosterone replacement therapy (TRT) has increased dramatically over the last 10 years. However, the safety of TRT has come into question with some studies suggestin...

journal_title：Neuroendocrinology

authors： Smith C,Contreras-Garza J,Cunningham RL,Wong JM,Vann PH,Metzger D,Kasanga E,Oppong-Gyebi A,Sumien N,Schreihofer DA

更新日期：2020-01-01 00:00:00

abstract：:The sheep exhibits a marked sex difference in the timing of the pubertal increase in luteinizing hormone (LH). Male lambs undergo a reduction in sensitivity to inhibitory steroid feedback, leading to an increase in LH by 10 weeks of age, but females remain hypersensitive until 30 weeks of age. Endogenous opioids suppr...

journal_title：Neuroendocrinology

authors： Wood RI,I'Anson H,Ebling FJ,Foster DL

更新日期：1992-12-01 00:00:00

abstract：:In situ hybridization was used to examine the effects of amygdala kindling on the expression of mRNAs for mineralocorticoid receptors (MR) and glucocorticoid receptors (GR) in the rat hippocampus. Kindling increased MR mRNA levels in the dentate gyrus of the hippocampus 4 h after the last seizure, and these levels rem...

journal_title：Neuroendocrinology

authors： Clark M,Smith MA,Weiss SR,Post RM

更新日期：1994-05-01 00:00:00

abstract：:The study was designed to determine whether the ability of central oxytocin (OT) to stimulate gonadotropin-releasing hormone (GnRH) on the afternoon of proestrus (PE) in the cycling female rat is mediated at the level of GnRH terminals within the median eminence (ME), or at higher hypothalamic levels where GnRH cell b...

journal_title：Neuroendocrinology

authors： Selvage D,Johnston CA

更新日期：2001-08-01 00:00:00

abstract：:There is extensive evidence that serotonin (5-HT) is implicated in the neuroendocrine control regulating the secretion of several anterior pituitary hormones. It has also been reported that the posterior pituitary is necessary for prolactin (PRL) response to 5-HT as well as to suckling, in which 5-HT implication has b...

journal_title：Neuroendocrinology

authors： Balsa JA,Sánchez-Franco F,Pazos F,Lara JI,Lorenzo MJ,Maldonado G,Cacicedo L

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:The amygdala receives afferent sensory input and processes information related to hydromineral balance. Angiotensin acts on and through the amygdala to stimulate thirst and sodium appetite. In addition, different angiotensins seem to play a role in cognition and learning mechanisms by acting on and through t...

journal_title：Neuroendocrinology

authors： Staschewski J,Kulisch C,Albrecht D

更新日期：2011-01-01 00:00:00