Comparative immunohistochemical study of the distribution of neuropeptide Y, growth hormone-releasing factor and the carboxyterminus of precursor protein GHRF in the human hypothalamic infundibular area.

abstract：:The A1 and A2 brainstem noradrenergic cell groups project to the hypothalamic paraventricular nucleus (PVN), which is involved in integrating the stress response. Bi-directional communication between the brain and immune system is well established, with both neuroendocrine and immune responses being activated by lipop...

journal_title：Neuroendocrinology

authors： Condé GL,Renshaw D,Zubelewicz B,Lightman SL,Harbuz MS

更新日期：1999-09-01 00:00:00

abstract：:Cell-intact patch-clamp recording was used to determine the electrophysiological responses of sheep anterior pituitary gonadotropes to stimulation with gonadotropin-releasing hormone (GnRH). Cells were identified prior to recording by reverse haemolytic plaque assay (RHPA), or using morphological criteria in preparati...

journal_title：Neuroendocrinology

authors： Heyward PM,Chen C,Clarke IJ

更新日期：1993-12-01 00:00:00

abstract：:Neuronal nitric oxide synthase, e.g. NADPH diaphorase (NADPH-d), catalyzes formation of the free radical, nitric oxide (NO), and occurs within brain structures that have functional significance for energy fuel homeostasis. The following studies examined whether populations of NADPH-d-positive neurons in the hypothalam...

journal_title：Neuroendocrinology

authors： Briski KP,Sylvester PW

更新日期：1999-03-01 00:00:00

abstract：:Single rat neurohypophyses were impaled on a platinum electrode, perifused with isotonic medium and fractions of perifusate collected each minute. Arginine vasopressin content of the fractions was measured by radioimmunoassay. The basal release of arginine vasopressin varied from 50 to 350 pg (0.02-0.14 mU/min) betwee...

journal_title：Neuroendocrinology

authors： Bicknell RJ,Leng G

更新日期：1981-11-01 00:00:00

abstract：BACKGROUND/AIMS:Abuse of toluene products (e.g., glue-sniffing) primarily occurs during adolescence and has been associated with appetite suppression and weight impairments. However, the metabolic phenotype arising from adolescent inhalant abuse has never been fully characterised, and its persistence during abstinence ...

journal_title：Neuroendocrinology

authors： Crossin R,Andrews ZB,Sims NA,Pang T,Mathai M,Gooi JH,Stefanidis A,Oldfield BJ,Lawrence AJ,Duncan JR

更新日期：2018-01-01 00:00:00

abstract：:Previous studies have indicated that 30 min of swimming in room temperature water is a potent stimulus for the secretion of beta-endorphin (beta E) from the intermediate lobe (IL) of the pituitary in rodents. Repeated daily challenge with this paradigm over days to weeks leads to a progressive increase in proopiomelan...

journal_title：Neuroendocrinology

authors： Young EA,Bronstein D,Akil H

更新日期：1993-09-01 00:00:00

abstract：:The sheep exhibits a marked sex difference in the timing of the pubertal increase in luteinizing hormone (LH). Male lambs undergo a reduction in sensitivity to inhibitory steroid feedback, leading to an increase in LH by 10 weeks of age, but females remain hypersensitive until 30 weeks of age. Endogenous opioids suppr...

journal_title：Neuroendocrinology

authors： Wood RI,I'Anson H,Ebling FJ,Foster DL

更新日期：1992-12-01 00:00:00

abstract：:Interleukin (IL)-6 in the hypothalamus and hindbrain is an important downstream mediator of suppression of body weight and food intake by glucagon-like peptide-1 (GLP-1) receptor stimulation. CNS GLP-1 is produced almost exclusively in prepro-glucagon neurons in the nucleus of the solitary tract. These neurons innerva...

journal_title：Neuroendocrinology

authors： Anesten F,Mishra D,Dalmau Gasull A,Engström-Ruud L,Bellman J,Palsdottir V,Zhang F,Trapp S,Skibicka KP,Poutanen M,Jansson JO

更新日期：2019-01-01 00:00:00

abstract：:Multiple unit activity (MUA) was recorded from the adrenocorticotropic area (n. posterior medialis hypothalami, PMH) of unrestrained resting pigeons throughout the 24 h period and compared with plasma corticosterone levels (B). Bilateral electrolytic lesions of the hippocampus suppressed diurnal variations of MUA and ...

journal_title：Neuroendocrinology

authors： Bouillé C,Baylé JD

更新日期：1978-01-01 00:00:00

abstract：:Allopregnanolone is a neuroactive steroid synthesized in rat gonads, adrenal cortex, and central nervous system. It has been suggested that sex steroid hormones might influence allopregnanolone concentrations but no clear data have ever been reported. The aim of the present study was to investigate the effects of admi...

journal_title：Neuroendocrinology

authors： Genazzani AR,Bernardi F,Stomati M,Monteleone P,Luisi S,Rubino S,Farzati A,Casarosa E,Luisi M,Petraglia F

更新日期：2000-09-01 00:00:00

abstract：:Chronic exposure to Delta(9)-tetrahydrocannabinol (Delta(9)-THC) increases corticotropin-releasing hormone (CRH) and proopiomelanocortin (POMC) gene expression in the rat hypothalamus. The levels of circulating gonadal steroids concurrently modulate both neuropeptides in male and female rats. However, it remains unkno...

journal_title：Neuroendocrinology

authors： Corchero J,Manzanares J,Fuentes JA

更新日期：2001-09-01 00:00:00

abstract：:A significant increase of cell multiplication in inoculated ascitic and solid tumors was demonstrated in both DBA/2 and C57BL/6 mice as well as in Wistar rats after radiofrequency lesions in the median hypothalamus (ventromedial and dorsomedial nuclei; part of arcuate nucleus). The following tests were performed: mito...

journal_title：Neuroendocrinology

authors： Bindoni M,Belluardo N,Marchese AE,Cardile V,Mudò G,Cella S,Laguidara A,Denatale G

更新日期：1986-01-01 00:00:00

abstract：:Although glutamate is the predominant excitatory amino acid in the vertebrate central nervous system (CNS) where it affects a variety of physiological processes and pathophysiological states, the role that glutamate receptors may play outside the CNS has not been clearly established. In the present study, the effects ...

journal_title：Neuroendocrinology

authors： Giovannucci DR,Stuenkel EL

更新日期：1995-08-01 00:00:00

abstract：:Electrical stimulation in the subfornical organ (SFO) alters the excitability of antidromically identified paraventricular nucleus neurons. Extracellular recordings demonstrate that the dominant effect of single stimuli delivered to the SFO on neurohypophyseal oxytocin and vasopressin containing neurons is an increase...

journal_title：Neuroendocrinology

authors： Ferguson AV,Day TA,Renaud LP

更新日期：1984-11-01 00:00:00

abstract：:The study was designed to determine whether the ability of central oxytocin (OT) to stimulate gonadotropin-releasing hormone (GnRH) on the afternoon of proestrus (PE) in the cycling female rat is mediated at the level of GnRH terminals within the median eminence (ME), or at higher hypothalamic levels where GnRH cell b...

journal_title：Neuroendocrinology

authors： Selvage D,Johnston CA

更新日期：2001-08-01 00:00:00

abstract：:Neonatal rats exhibit a period of diminished pituitary and adrenocortical responses to stress during the first 2 weeks of life. Since thyroid hormones are known to affect brain development, modulation of these responses to stress by alterations in thyroid hormone status have been investigated in hypothyroid (Hypo) and...

journal_title：Neuroendocrinology

authors： Walker CD,Sizonenko PC,Aubert ML

更新日期：1989-09-01 00:00:00

abstract：:The obese gene (OB) product, leptin, has been shown to exert control on metabolic processes such as food intake and body weight homeostasis, possibly through a neuropeptide Y (NPY) neurotransmission. More recently, leptin has been shown to control several neuroendocrine axes, modulating pituitary hormone secretions in...

journal_title：Neuroendocrinology

authors： Vuagnat BA,Pierroz DD,Lalaoui M,Englaro P,Pralong FP,Blum WF,Aubert ML

更新日期：1998-05-01 00:00:00

abstract：:Autoradiographic methods were used to study the location of estrogen-concentrating cells in the brain of the female hamster. In the hypothalamus, well-labelled cells were reliably found in the posterior medial preoptic area (MPOA), the anterior hypothalamus (AHA), and the ventromedial (VM), arcuate (ARC) and ventral p...

journal_title：Neuroendocrinology

authors： Krieger MS,Morrell JI,Pfaff DW

更新日期：1976-01-01 00:00:00

abstract：:Male Turkish hamsters received horizontal knife cuts within the hypothalamus to investigate the role of afferent and efferent projections of the paraventricular nucleus (PVN) in seasonal regulation of endocrine function. Following surgery, the animals were exposed to either a long (16 h light/8 h dark) or a short (8 h...

journal_title：Neuroendocrinology

authors： Badura LL,Goldman BD

更新日期：1992-04-01 00:00:00

abstract：:Recent work has demonstrated that the brain has the capacity to synthesize impressive amounts of the gases nitric oxide (NO) and carbon monoxide (CO). There is growing evidence that these gaseous molecules function as novel neural messengers in the brain. This article reviews the pertinent literature concerning the pu...

journal_title：Neuroendocrinology

authors： Brann DW,Bhat GK,Lamar CA,Mahesh VB

更新日期：1997-06-01 00:00:00

abstract：BACKGROUND:Kisspeptins are recognized as important stimulators of gonadotropin-releasing hormone (GnRH) and gonadotropin secretion. In sheep, the nonbreeding (anestrous) period is characterized by reduced Kiss1 mRNA expression in the hypothalamus. The aim of the present study was to determine whether the response to ki...

journal_title：Neuroendocrinology

authors： Smith JT,Saleh SN,Clarke IJ

更新日期：2009-01-01 00:00:00

abstract：:Incubation of cultured goldfish pituitary cells with 10 nM to 1 microM apomorphine (APO), a non-selective dopamine agonist, increased growth hormone (GH) release in a dose-dependent manner. GH release was also stimulated in a dose-dependent manner by 0.1 nM to 1 microM salmon gonadotropin (GTH)-releasing hormone (sGnR...

journal_title：Neuroendocrinology

authors： Chang JP,Yu KL,Wong AO,Peter RE

更新日期：1990-06-01 00:00:00

abstract：:Following the procedure of Jeffcoate et al. [1974] we have successfully obtained a specific antiserum to LH-RH in rabbits, and are utilizing our antibody to study the synthesis of LH-RH by rat hypothalamic tissues in vitro. Our antibody, used at a dilution of 1:20,000, binds 37% of added 125I-labelled LH-RH, and cross...

journal_title：Neuroendocrinology

authors： Hall RW,Steinberger E

更新日期：1976-01-01 00:00:00

abstract：:Pregnant rats were kept on an ethanol-containing (6% w/v) liquid diet from the 13th day of gestation and serum growth hormone (GH) levels were determined in the offspring after four different experimental paradigms. In controls, administration of cyproheptadine (a serotonin-blocking agent), or insulin, or exposure to ...

journal_title：Neuroendocrinology

authors： Thadani PV

更新日期：1984-04-01 00:00:00

abstract：:Lactotrophs, gonadotrophs, thyrotrophs and somatotrophs of the rat anterior pituitary (AP) express 68-kDa neurofilaments (NF68) and other neuronal markers. NF68 expression in the AP appears to be estrogen-dependent, but its significance is unknown. The aims of this work were: (1) to establish the expression pattern of...

journal_title：Neuroendocrinology

authors： Fiordelisio T,Millán-Aldaco D,Hernández-Cruz A

更新日期：2006-01-01 00:00:00

abstract：:Dopaminergic agonists are effective in vivo in inhibiting lactotrope proliferation and prolactin (PRL)-secreting pituitary tumors. The purpose of the present study was to demonstrate in vitro actions of dopaminergic agents on proliferation and cell shape of rat lactotropes. Anterior pituitary cells cultured with serum...

journal_title：Neuroendocrinology

authors： Arita J,Hashi A,Hoshi K,Mazawa S,Suzuki S

更新日期：1998-09-01 00:00:00

abstract：:Studies were undertaken to investigate the nature of receptors involved in the prolactin-releasing action of histamine in male rats. The increase of plasma prolactin levels induced by third-ventricle injection of histamine was blocked by intraventricular injection of ranitidine, an H2-antagonist, but not by systemic a...

journal_title：Neuroendocrinology

authors： Donoso AO,Zárate MB,Seltzer A

更新日期：1983-06-01 00:00:00

abstract：:Prolactin release from primary cultured pituitary cells was investigated using a dynamic perifusion system. Although epinephrine (1 mumol/l) produced an elevation in the mean value of the prolactin concentration at the onset of the perifusion, the elevation was not statistically significant, and the overall effect of ...

journal_title：Neuroendocrinology

authors： Shin SH,Barton RE

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND:Synaptic plasticity is the neuronal capacity to modify the function and structure of dendritic spines (DS) in response to neuromodulators. Sex steroids, particularly 17β-estradiol (E2) and progesterone (P4), are key regulators in the control of DS formation through multiprotein complexes including WAVE1 prot...

journal_title：Neuroendocrinology

authors： Uzair ID,Flamini MI,Sanchez AM

更新日期：2020-01-01 00:00:00

abstract：:The effect of sonicated suspensions of phosphatidylserine (PS), an acidic phospholipid, was investigated on prolactin secretion utilizing in vivo and in vitro approaches. Acute and chronic administration of PS reduced plasma prolactin levels during different phases of circadian rhythms. The phospholipid was able to in...

journal_title：Neuroendocrinology

authors： Canonico PL,Annunziato L,Toffano G,Bernardini R,Stanzani S,Foti M,Clementi G,Drago F,Scapagnini U

更新日期：1981-12-01 00:00:00