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Age-related responses in circulating markers of redox status in healthy adolescents and adults during the course of a training macrocycle.

Abstract：

:Redox status changes during an annual training cycle in young and adult track and field athletes and possible differences between the two age groups were assessed. Forty-six individuals (24 children and 22 adults) were assigned to four groups: trained adolescents, (TAD, N = 13), untrained adolescents (UAD, N = 11), trained adults (TA, N = 12), and untrained adults (UA, N = 10). Aerobic capacity and redox status related variables [total antioxidant capacity (TAC), glutathione (GSH), catalase activity, TBARS, protein carbonyls (PC), uric acid, and bilirubin] were assessed at rest and in response to a time-trial bout before training, at mid- and posttraining. TAC, catalase activity, TBARS, PC, uric acid, and bilirubin increased and GSH declined in all groups in response to acute exercise independent of training status and age. Training improved aerobic capacity, TAC, and GSH at rest and in response to exercise. Age affected basal and exercise-induced responses since adults demonstrated a greater TAC and GSH levels at rest and a greater rise of TBARS, protein carbonyls, and TAC and decline of GSH in response to exercise. Catalase activity, uric acid, and bilirubin responses were comparable among groups. These results suggest that acute exercise, age, and training modulate the antioxidant reserves of the body.

journal_name

Oxid Med Cell Longev

journal_title

Oxidative medicine and cellular longevity

authors

Zalavras A,Fatouros IG,Deli CK,Draganidis D,Theodorou AA,Soulas D,Koutsioras Y,Koutedakis Y,Jamurtas AZ

doi

10.1155/2015/283921

subject

Has Abstract

pub_date

2015-01-01 00:00:00

pages

283921

eissn

1942-0900

issn

1942-0994

journal_volume

2015

pub_type

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