Announcing the publication of the WHO immunological basis for immunization series module on influenza vaccines.

Abstract:

:In 2017, the World Health Organization (WHO) published a document aimed at facilitating influenza vaccine introduction and use in low- and middle-income countries. The document "The Immunological Basis for Immunization Series: Influenza Vaccines" is freely available on the WHO website. The main purpose of this document is to give immunization managers and vaccination professionals an authoritative but easily-understood overview of the scientific basis of influenza vaccination and the immunological basis for the WHO position on influenza vaccines. The influenza vaccine document comprises one module of the WHO Immunological Basis for Immunization series. We invite the immunization community to use these references, and we hope the influenza vaccine module will be a valuable resource for persons who manage and monitor influenza vaccine programs, particularly in low- and middle-income countries.

journal_name

Vaccine

journal_title

Vaccine

authors

Ortiz JR,Hombach J

doi

10.1016/j.vaccine.2017.09.010

subject

Has Abstract

pub_date

2018-09-05 00:00:00

pages

5504-5505

issue

37

eissn

0264-410X

issn

1873-2518

pii

S0264-410X(17)31226-4

journal_volume

36

pub_type

杂志文章

相关文献

VACCINE文献大全
  • Advancing a vaccine to prevent hookworm disease and anemia.

    abstract::A human hookworm vaccine is under development and in clinical trials in Africa and the Americas. The vaccine contains the Na-APR-1 and Na-GST-1 antigens. It elicits neutralizing antibodies that interfere with establishment of the adult hookworm in the gut and the ability of the parasite to feed on blood. The vaccine t...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2016.03.078

    authors: Hotez PJ,Beaumier CM,Gillespie PM,Strych U,Hayward T,Bottazzi ME

    更新日期:2016-06-03 00:00:00

  • Gene expression profiling toward the next generation safety control of influenza vaccines and adjuvants in Japan.

    abstract::Influenza becomes epidemic worldwide every year, and many individuals receive vaccination annually. Quality control relating to safety and potency of influenza vaccines is important to maintain public confidence. The safety of influenza vaccines has been assessed by clinical trials, and animal safety tests are perform...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2018.09.021

    authors: Momose H,Sasaki E,Kuramitsu M,Hamaguchi I,Mizukami T

    更新日期:2018-10-15 00:00:00

  • Molecular adjuvants for malaria DNA vaccines based on the modulation of host-cell apoptosis.

    abstract::Malaria represents a major global health problem but despite extensive efforts, no effective vaccine is available. Various vaccine candidates have been developed that provide protection in animal models, such as a gene gun-delivered DNA vaccine encoding the circumsporozoite protein (CSP) of Plasmodium berghei. A commo...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2009.06.059

    authors: Bergmann-Leitner ES,Leitner WW,Duncan EH,Savranskaya T,Angov E

    更新日期:2009-09-18 00:00:00

  • Short and long-term immunogenicity and safety following the 23-valent polysaccharide pneumococcal vaccine in juvenile idiopathic arthritis patients under conventional DMARDs with or without anti-TNF therapy.

    abstract:OBJECTIVES:To assess immunogenicity and safety of the 23-valent polysaccharide pneumococcal vaccine (PPV23) in juvenile idiopathic arthritis (JIA) patients under conventional DMARDs with or without anti-TNF therapy. The influences of demographic data, disease activity and treatment on immune response and the potential ...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2014.12.030

    authors: Aikawa NE,França IL,Ribeiro AC,Sallum AM,Bonfa E,Silva CA

    更新日期:2015-01-29 00:00:00

  • Cross-reactive immune responses in mice after genetic vaccination with cDNA encoding hantavirus nucleocapsid proteins.

    abstract::Hantaviruses cause hemorrhagic fever with renal syndrome (HFRS) in about 150,000 individuals in Eurasia, and several hundred cases of hantavirus pulmonary syndrome (HPS) on the American continent annually. There is consequently a need for rapid diagnostics and effective prevention of hantaviral infections. In this stu...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2006.09.082

    authors: Lindkvist M,Lahti K,Lilliehöök B,Holmström A,Ahlm C,Bucht G

    更新日期:2007-02-19 00:00:00

  • Novel lipopeptides of ESAT-6 induce strong protective immunity against Mycobacterium tuberculosis: Routes of immunization and TLR agonists critically impact vaccine's efficacy.

    abstract::Mycobacterium tuberculosis (Mtb), the bacterial cause of tuberculosis, is a leading infectious agent worldwide. The development of a new vaccine against Mtb is essential to control global spread of tuberculosis, since the current vaccine BCG is not very effective and antibiotic resistance is a serious, burgeoning prob...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2016.08.075

    authors: Gupta N,Vedi S,Kunimoto DY,Agrawal B,Kumar R

    更新日期:2016-11-04 00:00:00

  • Post-exposure rabies prophylaxis: establishing effectiveness of abbreviated treatments.

    abstract::Several publications have reported recently the apparently successful use of human diploid cell rabies vaccine (HDCV) in volumes of less than the 6 X 1.0 cm3 dosage schedule currently recommended by the World Health Organization for post-exposure rabies prophylaxis. The newer proposed treatments are advocated to econo...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/s0264-410x(85)90035-0

    authors: Gross EM,Bearman JE

    更新日期:1985-09-01 00:00:00

  • Hyporesponsiveness to re-challenge dose following pneumococcal polysaccharide vaccine at 12 months of age, a randomized controlled trial.

    abstract:BACKGROUND:To evaluate the immunological impact of the 23-valent pneumococcal polysaccharide vaccine (23vPPS) at 12 months, for children who have received zero to three infant doses of seven-valent pneumococcal conjugate vaccine (PCV), on responses to a subsequent exposure to a small dose of 23vPPS (mPPS). METHODS:Fiv...

    journal_title:Vaccine

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.vaccine.2010.02.087

    authors: Russell FM,Carapetis JR,Balloch A,Licciardi PV,Jenney AW,Tikoduadua L,Waqatakirewa L,Pryor J,Nelson J,Byrnes GB,Cheung YB,Tang ML,Mulholland EK

    更新日期:2010-04-26 00:00:00

  • A dose-response evaluation of inactivated influenza vaccine given intranasally and intramuscularly to healthy young adults.

    abstract::Epidemic influenza occurs annually throughout the world and is accompanied by excess morbidity and mortality. Increasing the antigen content and topical administration of vaccine are two strategies being explored to improve the immune responses to trivalent inactivated influenza vaccine (TIV). We conducted a randomize...

    journal_title:Vaccine

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.vaccine.2007.05.002

    authors: Atmar RL,Keitel WA,Cate TR,Munoz FM,Ruben F,Couch RB

    更新日期:2007-07-20 00:00:00

  • Current approaches to the development of vaccines against disease caused by respiratory syncytial virus (RSV) and parainfluenza virus (PIV). A meeting report of the WHO Programme for Vaccine Development.

    abstract::The paramyxoviruses respiratory syncytial virus (RSV) and parainfluenza virus type 3 (PIV3) are the two most common agents of severe lower respiratory tract disease in infants and children throughout the world. RSV causes yearly epidemics of bronchiolitis and pneumonia in infants and young children, while PIV3 is a co...

    journal_title:Vaccine

    pub_type:

    doi:10.1016/0264-410x(95)98266-d

    authors: Crowe JE Jr

    更新日期:1995-03-01 00:00:00

  • A pilot study to quantify parental anxiety associated with enrollment of an infant or toddler in a phase III vaccine trial.

    abstract::We sought to measure the anxiety felt by parents at the time of entry into a randomized controlled vaccine trial, and to determine if anxiety level was associated with parental demographic variables or past experience. The children were 2-month-old infants entering a randomized controlled clinical trial (RCT) of a dip...

    journal_title:Vaccine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0264-410x(03)00304-9

    authors: Langley JM,Halperin SA,Smith B

    更新日期:2003-09-08 00:00:00

  • Immunotherapy with combined DNA vaccines is an effective treatment for M. bovis infection in cattle.

    abstract::Mycobacterium bovis causes tuberculosis in cattle. Because current therapies inadequately prevent disease spread, new therapies for M. bovis infections are urgently needed. We treated M. bovis-infected cattle with combinations of DNA vaccines, resulting in significantly reduced pulmonary bacterial loads compared with ...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2008.12.055

    authors: Hu XD,Chen ST,Yu DH,Li SX,Cai H

    更新日期:2009-02-25 00:00:00

  • Artesunate enhances the immune response of rabies vaccine as an adjuvant.

    abstract::Rabies is an ancient zoonosis that continues to be an important health problem worldwide. Vaccination with rabies vaccine is the most important strategy to prevent rabies. Adjuvants contribute to the immune response of viral vaccine. The aim of this study was to investigate whether artemisinin derivatives artesunate a...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2019.09.077

    authors: Luo J,Zhang Y,He H,Liu Q,Huang S,Guo X

    更新日期:2019-12-03 00:00:00

  • PolyI:polyC12U adjuvant-combined intranasal vaccine protects mice against highly pathogenic H5N1 influenza virus variants.

    abstract::The highly pathogenic avian H5N1 influenza virus has the potential to incite a global pandemic. Therefore, there is an urgent need to develop effective vaccines against these viruses. Because it is difficult to predict which strain of influenza will cause a pandemic, it is advantageous to develop vaccines that will co...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2009.04.074

    authors: Ichinohe T,Ainai A,Tashiro M,Sata T,Hasegawa H

    更新日期:2009-10-23 00:00:00

  • A DNA vaccine targeting the receptor-binding domain of Clostridium difficile toxin A.

    abstract::Clostridium difficile is a pathogen with increasing severity for which host antibody responses provide protection from disease. DNA vaccination has several advantages compared to traditional vaccine methods, however no study has examined this platform against C. difficile toxins. A synthetic gene was created encoding ...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2009.03.058

    authors: Gardiner DF,Rosenberg T,Zaharatos J,Franco D,Ho DD

    更新日期:2009-06-02 00:00:00

  • Tick-borne encephalitis--pathogenesis, clinical course and long-term follow-up.

    abstract::The prospective studies available today confirm the experience gained from several retrospective studies that TBE is a disease with a severe acute clinical course and considerable long-term morbidity. A defined post-encephalitic TBE syndrome exists, causing long-lasting morbidity that often affects the quality of life...

    journal_title:Vaccine

    pub_type: 杂志文章,评审

    doi:10.1016/s0264-410x(02)00811-3

    authors: Haglund M,Günther G

    更新日期:2003-04-01 00:00:00

  • Dendritic cells expressing BTLA induces CD8+ T cell tolerance and attenuates the severity of diabetes.

    abstract::Numerous evidence demonstrate Type 1 diabetes (T1D) is due to a loss of immune tolerance to islet antigens, and CD8(+) T cells play an important role in the development of T1D in NOD mice. The novel coinhibitory receptor BTLA may have a regulatory role in maintaining peripheral tolerance, however, its role in autoimmu...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2011.07.125

    authors: Li S,Zhang M,Xiang F,Zhao J,Jiang C,Zhu J

    更新日期:2011-10-13 00:00:00

  • Avipox-based simian immunodeficiency virus (SIV) vaccines elicit a high frequency of SIV-specific CD4+ and CD8+ T-cell responses in vaccinia-experienced SIVmac251-infected macaques.

    abstract::The ability of ALVAC- or fowlpox-based simian immunodeficiency virus (SIV) vaccines to boost SIV-specific CD4+ and CD8+ T-cell responses was tested in 10 vaccinia-experienced macaques infected with SIVmac251. The CD8+ T-cell response to the dominant Gag(181-189) CM9 was quantitated in seven Mamu-A*01-positive macaques...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2003.08.028

    authors: Nacsa J,Radaelli A,Edghill-Smith Y,Venzon D,Tsai WP,Morghen Cde G,Panicali D,Tartaglia J,Franchini G

    更新日期:2004-01-26 00:00:00

  • Immunogenicity and safety of a booster vaccination against tick-borne encephalitis more than 3 years following the last immunisation.

    abstract::This study investigated the immune response and safety in 430 adults, when boosted more than 3 years after primary or booster TBE immunisation as measured by neutralization test (NT) and ELISA. Tested by NT, the post-booster day 21 geometric mean titer (GMT) was 331 and 142 for the 18-49 and > or =50 years old, respec...

    journal_title:Vaccine

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.vaccine.2004.07.002

    authors: Rendi-Wagner P,Kundi M,Zent O,Banzhoff A,Jaehnig P,Stemberger R,Dvorak G,Grumbeck E,Laaber B,Kollaritsch H

    更新日期:2004-12-09 00:00:00

  • Knowledge of human papillomavirus (HPV) and HPV vaccination: an international comparison.

    abstract::Since vaccination against human papillomavirus (HPV) became available, awareness of HPV has dramatically increased. Implementation of a vaccine program varies internationally yet no studies have explored the influence this has on the public's knowledge of HPV. The present study aimed to explore differences in awarenes...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2012.11.083

    authors: Marlow LA,Zimet GD,McCaffery KJ,Ostini R,Waller J

    更新日期:2013-01-21 00:00:00

  • Epidemiology of varicella in Haidian district, Beijing, China-2007-2015.

    abstract:BACKGROUND:1-Dose varicella vaccination was recommended for children in Beijing before November 2012. To further control school-based outbreaks and decrease incidence, a 2-dose vaccination was implemented in 2013. We described the varicella epidemiology and assessed impact of the 2-dose vaccination in Haidian district,...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2017.03.044

    authors: Fu J,Jiang C,Wang J,Zhao F,Ma T,Shi R,Zhao Y,Zhang X

    更新日期:2017-04-25 00:00:00

  • Genetic fusion of proteins to the SIV Tat protein enhances their immunogenicity.

    abstract::The potential of genetically fusing recombinant proteins to the simian immunodeficiency virus (SIV) Tat protein has been investigated. The recombinant SIV Tat protein was initially expressed in very low amounts in E. coli, but optimization of the coding sequence for translation in the bacterial host significantly impr...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2005.09.012

    authors: Chen YH,Diassiti A,Randall RE

    更新日期:2006-02-06 00:00:00

  • Induction of a secretory IgA response in the murine female urogenital tract by immunization of the lungs with liposome-supplemented viral subunit antigen.

    abstract::This study demonstrates that liposomes administered to the lower respiratory tract of mice have the capacity to stimulate secretory IgA (s-IgA) antibody production in the female urogenital system. Total respiratory tract immunization of mice with influenza virus subunit antigen simply mixed with negatively charged lip...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/0264-410x(94)00062-r

    authors: de Haan A,Renegar KB,Small PA Jr,Wilschut J

    更新日期:1995-05-01 00:00:00

  • Construction and in vitro characterization of a molecularly cloned human immunodeficiency virus type 1 library.

    abstract::Development of a safe and effective vaccine against human immunodeficiency virus (HIV) is urgent, but many concerns regarding the safety and efficacy of the currently developing vaccines remain. A major hindrance in HIV vaccine development is the genetic diversity, a hallmark of HIV biology, and a poor understanding o...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/s0264-410x(01)00429-7

    authors: Mukai T,Kurosu T,Kinomoto M,Komoto S,Shiraga M,Auwanit W,Ikuta K

    更新日期:2002-01-15 00:00:00

  • Measles, mumps, and rubella antibodies in children 5-6 years after immunization: effect of vaccine type and age at vaccination.

    abstract::The levels of antibody against measles, mumps, and rubella were determined at 5-6 years postimmunization in 468 children vaccinated with two different trivalent vaccines. The proportions of children without detectable antibody levels were 12 and 3.6% for measles (p < 0.001), 14.9 and 7% for mumps (p = 0.006), and 3.3 ...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/0264-410x(95)00098-l

    authors: Boulianne N,De Serres G,Ratnam S,Ward BJ,Joly JR,Duval B

    更新日期:1995-11-01 00:00:00

  • Vaccination of newborn mice induces a strong protective immune response against respiratory and genital challenges with Chlamydia trachomatis.

    abstract::Chlamydia trachomatis infections can occur early in life and may result in long-term sequelae. To assess the feasibility of implementing a vaccine in newborns, groups of 2-day-old BALB/c mice were immunized intranasally (i.n.) with 1x10(4) inclusion forming units (IFU) of C. trachomatis mouse pneumonitis (MoPn). As a ...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2005.06.026

    authors: Pal S,Peterson EM,de la Maza LM

    更新日期:2005-11-16 00:00:00

  • Epidemiological patterns of hepatitis A in different parts of the world.

    abstract::Serological surveys in many communities show a high prevalence of antibodies to hepatitis A virus (HAV) in people over the age of 50 years. However, few of that age can recall a previous episode of hepatitis, indicating that subclinical infections are common. The outcome of infection with HAV depends on the age at whi...

    journal_title:Vaccine

    pub_type: 杂志文章,评审

    doi:10.1016/0264-410x(92)90544-t

    authors: Gust ID

    更新日期:1992-01-01 00:00:00

  • Influence of glycosylphosphatidylinositol anchorage on the efficacy of DNA vaccines encoding Plasmodium yoelii merozoite surface protein 4/5.

    abstract::Immune responses induced to DNA vaccination vary considerably and depend on a variety of factors, including the physical form in which the antigen is expressed by target cells and presented to the immune system. Data on the effect of these factors will aid improved design of DNA vaccines and facilitate their further d...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2005.03.016

    authors: Wang L,Kedzierski L,Schofield L,Coppel RL

    更新日期:2005-07-14 00:00:00

  • WHO Working Group on revision of the Manual of Laboratory Methods for Testing DTP Vaccines-Report of two meetings held on 20-21 July 2006 and 28-30 March 2007, Geneva, Switzerland.

    abstract::This report reflects the discussion and conclusions of a WHO group of experts from National Regulatory Authorities (NRAs), National Control Laboratories (NCLs), vaccine industries and other relevant institutions involved in standardization and control of diphtheria, tetanus and pertussis vaccines (DTP), held on 20-21 ...

    journal_title:Vaccine

    pub_type:

    doi:10.1016/j.vaccine.2008.02.013

    authors: Corbel MJ,Das RG,Lei D,Xing DK,Horiuchi Y,Dobbelaer R,WHO Working Group.

    更新日期:2008-04-07 00:00:00

  • Willingness to participate in Ebola viral disease vaccine trials and receive vaccination by health workers in a tertiary hospital in Ile-Ife, Southwest Nigeria.

    abstract:BACKGROUND:Ebola viral disease (EVD) epidemic need to be contained through means which include vaccination of susceptible population. Vaccination has eradicated major killer diseases. OBJECTIVE:The study determined the health workers willingness to participate in EVD vaccine clinical trials and receive EVD vaccine. M...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2016.10.004

    authors: Olowookere SA,Abioye-Kuteyi EA,Adekanle O

    更新日期:2016-11-11 00:00:00