The Leukemia Inhibitory Factor Receptor Gene Is a Direct Target of RUNX1.

abstract：:Heat shock protein (HSP) levels are elevated in breast cancer and are molecular targets for novel therapies. HSPs were first observed as proteins induced in massive amounts in normal cells exposed to stresses that lead to protein denaturation. Their expanded expression in mammary carcinoma appears to be largely due to...

journal_title：Journal of cellular biochemistry

authors： Calderwood SK,Gong J

更新日期：2012-04-01 00:00:00

abstract：:Herbal plants are enriched with compounds with a wide range of biological activities. Furanodiene is a sesquiterpene isolated from Rhizoma Curcumae. Growing evidence shows furanodiene exhibits diversified activities of hepatoprotection, anti-inflammation, anti-angiogenesis, and anti-tumor. However, its biological acti...

journal_title：Journal of cellular biochemistry

authors： Zhong ZF,Li YB,Wang SP,Tan W,Chen XP,Chen MW,Wang YT

更新日期：2012-08-01 00:00:00

abstract：:Tumor necrosis factor-alpha (TNF-alpha) mediated attenuation of insulin signaling pathway is an important cause in several disorders like obesity, obesity linked diabetes mellitus. TNF-alpha actions vary depending upon concentration and time of exposure in various cells. In the present study, the effects of long-term ...

journal_title：Journal of cellular biochemistry

authors： Gupta D,Varma S,Khandelwal RL

更新日期：2007-02-15 00:00:00

abstract：:Long non-coding RNAs (lncRNAs) can participate in the pathological process of multiple myeloma (MM) via regulation of specific gene expression and function. This research aimed to study the role of MALAT-1 and the underlying mechanism in MM. In this study, the expression of MALAT-1 and HMGB1 protein in the bone marrow...

journal_title：Journal of cellular biochemistry

authors： Gao D,Lv AE,Li HP,Han DH,Zhang YP

更新日期：2017-10-01 00:00:00

abstract：:Transplantation of functional insulin-producing cells (IPCs) provides a novel mode for insulin replacement, but is often accompanied by many undesirable side effects. Our previous studies suggested that IPCs could not mimic the physiological regulation of insulin secretion performed by pancreatic beta cells. To obtain...

journal_title：Journal of cellular biochemistry

authors： Shi Q,Luo S,Jia H,Feng L,Lu X,Zhou L,Cai J

更新日期：2013-10-01 00:00:00

abstract：:This study aims to investigate how microRNA-375 (miR-375) improves immune function by regulating liver macrophages (Kupffer cells) in mice with liver failure. Forty mice were divided into ConA-1h, ConA-3h, ConA-6h, and control groups, with 10 mice in each group. Mice models of liver failure were established by injecti...

journal_title：Journal of cellular biochemistry

authors： Ke QH,Chen HY,He ZL,Lv Z,Xu XF,Qian YG,Zheng SS

更新日期：2019-01-01 00:00:00

abstract：:The basement membrane (BM) protein laminin-332 (Lm332) (laminin-5) has unique activity and structure as compared with other laminins: it strongly promotes cellular adhesion and migration, and its alpha3, beta3, and gamma2 chains are all truncated in their N-terminal regions (short arms). In the present study, we inves...

journal_title：Journal of cellular biochemistry

authors： Nakashima Y,Kariya Y,Miyazaki K

更新日期：2007-02-15 00:00:00

abstract：:Fibroblast-collagen matrix contraction has been used as a model system to study how cells organize connective tissue. Previous work showed that lysophosphatidic acid (LPA)-stimulated floating collagen matrix contraction is independent of Rho kinase while platelet-derived growth factor (PDGF)-stimulated contraction is ...

journal_title：Journal of cellular biochemistry

authors： Abe M,Sogabe Y,Syuto T,Yokoyama Y,Ishikawa O

更新日期：2007-12-01 00:00:00

abstract：:The cellular basis of metastasis is poorly understood. An important step to understanding this process is to be able to visualize the routes by which cancer cells migrate from the primary tumor to various distant sites to eventually form metastasis. Our laboratory previously developed single-cell in vivo imaging using...

journal_title：Journal of cellular biochemistry

authors： Zhang Y,Wang X,Hoffman RM,Seki N

更新日期：2016-04-01 00:00:00

abstract：:Receptor activator of NF-kappaB ligand (RANKL) is crucial in osteoclastogenesis but signaling events involved in osteoclast differentiation are far from complete and other signals may play a role in osteoclastogenesis. A more direct pathway for cellular crosstalk is provided by gap junction intercellular channel, whic...

journal_title：Journal of cellular biochemistry

authors： Matemba SF,Lie A,Ransjö M

更新日期：2006-10-01 00:00:00

abstract：:Bone formation is under the control of a set of transcription factors. Ids are inhibitory helix-loop-helix (HLH) transcription factors and expression of Id genes in osteoblasts is under the control of calciotropic agents such as BMP and vitamin D. However, the function of Ids during bone formation in vivo has not yet ...

journal_title：Journal of cellular biochemistry

authors： Maeda Y,Tsuji K,Nifuji A,Noda M

更新日期：2004-10-01 00:00:00

abstract：OBJECTIVE:Whether obesity categories can be used to predict cardiovascular disease (CVD) in Chinese adults remains unclear. This aim of this study was to examine the predictive values of obesity categories for CVD risk factors in Chinese adults. METHODS:This study comprised a sample size of 3480 men and 6364 women age...

journal_title：Journal of cellular biochemistry

authors： Yin D,Yan Y,Xu N,Hui Y,Han G,Ma N,Yang C,Wang G

更新日期：2018-11-02 00:00:00

abstract：:We investigated the early effects of the anti-idiotypic antibody (clone 1D5), which recognized the estrogen receptor (ER), on cytosolic free calcium concentration ([Ca2+]i) and its long term effects on creatine kinase (CK) specific activity in female human and rat osteoblasts. These actions were compared to the known ...

journal_title：Journal of cellular biochemistry

authors： Sömjen D,Kohen F,Lieberherr M

更新日期：1997-04-01 00:00:00

abstract：:Recombinant human apolipoprotein E3 (apoE), purified from E. coli, inhibited the proliferation of several cell types, including endothelial cells and tumor cells in a dose- and time-dependent manner. ApoE inhibited both de novo DNA synthesis and proliferation as assessed by an increase in cell number. Maximal inhibiti...

journal_title：Journal of cellular biochemistry

authors： Vogel T,Guo NH,Guy R,Drezlich N,Krutzsch HC,Blake DA,Panet A,Roberts DD

更新日期：1994-03-01 00:00:00

abstract：:Acetaminophen (APAP) is a widely used over-the-counter analgesic and antipyretic. It can cause hepatotoxicity. Recent studies demonstrated that hydrogen sulfide (H2 S) exhibits cell protection in several cell types. This study was designed to investigate whether H 2 S ameliorated APAP-induced acute liver injury and to...

journal_title：Journal of cellular biochemistry

authors： Li X,Lin J,Lin Y,Huang Z,Pan Y,Cui P,Yu C,Cai C,Xia J

更新日期：2019-03-01 00:00:00

abstract：:Burkitt lymphoma (BL) commonly exhibits Epstein-Barr virus (EBV) positivity associated with latent chronic infection. Models of acute EBV infection have been associated with cellular resistance to apoptosis. However, the effect of latent long-term EBV infection on apoptosis induced by drugs is not well defined. To det...

journal_title：Journal of cellular biochemistry

authors： Lima RT,Seca H,Soares P,Nascimento MS,Vasconcelos MH

更新日期：2011-01-01 00:00:00

abstract：:We previously described a color-coded imaging model that can quantify the length of nascent blood vessels using Gelfoam® implanted in nestin-driven green fluorescent protein (ND-GFP) nude mice. In ND-GFP mice, nascent blood vessels are labeled with GFP. We report here that osteosarcoma cells promote angiogenesis in th...

journal_title：Journal of cellular biochemistry

authors： Uehara F,Tome Y,Miwa S,Hiroshima Y,Yano S,Yamamoto M,Mii S,Maehara H,Bouvet M,Kanaya F,Hoffman RM

更新日期：2014-09-01 00:00:00

abstract：:The principal problem arising from prostate cancer (PCa) is its propensity to metastasize to bones, and it's crucial to understand the mechanism of tumor progression to metastasis in order to develop therapies that may reduce the morbidity and mortality of PCa patients. Although we had identified that microRNA(miR)-14...

journal_title：Journal of cellular biochemistry

authors： Guo W,Ren D,Chen X,Tu X,Huang S,Wang M,Song L,Zou X,Peng X

更新日期：2013-07-01 00:00:00

abstract：:MicroRNAs (miRNAs) are short noncoding ribonucleic acids known to affect gene expression at the translational level and there is mounting evidence that miRNAs play a role in the function of tumor-associated macrophages (TAMs). To aid the functional analyses of miRNAs in an in-vitro model of TAMs known as M2 macrophage...

journal_title：Journal of cellular biochemistry

authors： Ng YS,Roca H,Fuller D,Sud S,Pienta KJ

更新日期：2012-05-01 00:00:00

abstract：:Micromolar concentrations (0.5 approximately 5 microM) of all-trans geranylgeranoic acid (GGA) induced cell death in a guinea pig cell line, 104C1, whereas under the same conditions GGA was unable to kill 104C1/O4C, a clone established from 104C1 cells by transfection of them with the human phospholipid hydroperoxide ...

journal_title：Journal of cellular biochemistry

authors： Shidoji Y,Okamoto K,Muto Y,Komura S,Ohishi N,Yagi K

更新日期：2006-01-01 00:00:00

abstract：:Successful implantation and placentation requires that extravillous cytotrophoblast acquires an endovascular phenotype and remodels uterine spiral arteries. Defects in this mechanism correlate with severe obstetric complications as implantation failure and preeclampsia. Lysophosphatidic acid (LPA) participates in embr...

journal_title：Journal of cellular biochemistry

authors： Beltrame JS,Sordelli MS,Cañumil VA,Franchi AM,Ribeiro ML

更新日期：2018-01-01 00:00:00

abstract：:The proteins of 14-3-3 family are substantially involved in the regulation of many biological processes including the apoptosis. We studied the changes in the expression of five 14-3-3 isoforms (beta, gamma, epsilon, tau, and zeta) during the apoptosis of JURL-MK1 and K562 cells. The expression level of all these prot...

journal_title：Journal of cellular biochemistry

authors： Kuzelová K,Grebenová D,Pluskalová M,Kavan D,Halada P,Hrkal Z

更新日期：2009-03-01 00:00:00

abstract：:The activity of S6 kinases (S6K) is highly induced in cancer cells highlighting an essential role in carcinogenesis. The S6K family has two members: S6K1 and S6K2 which bear common as well as distinct features. In an attempt to identify S6K2 unique sequence features compared to S6K1, we applied extensive bioinformatic...

journal_title：Journal of cellular biochemistry

authors： Ismail HM,Hurd PJ,Khalil MI,Kouzarides T,Bannister A,Gout I

更新日期：2014-06-01 00:00:00

abstract：:We previously identified human CAP, a homolog of the yeast adenylyl cyclase-associated protein. Previous studies suggest that the N-terminal and C-terminal domains of CAP have distinct functions. We have explored the interactions of human CAP with various proteins. First, by performing yeast two-hybrid screens, we hav...

journal_title：Journal of cellular biochemistry

authors： Hubberstey A,Yu G,Loewith R,Lakusta C,Young D

更新日期：1996-06-01 00:00:00

abstract：:To find the key factors that were involved in the survival and vascular endothelial differentiation of chick blatodisc induced by fibroblast growth factor 2 (FGF-2), we built a chick vasculogenesis model in vitro. Subsequently, the activities of phosphatidylcholine-specific phospholipase C (PC-PLC), including Ca(2+)-d...

journal_title：Journal of cellular biochemistry

authors： Zhao J,Zhao B,Wang W,Huang B,Zhang S,Miao J

更新日期：2007-10-01 00:00:00

abstract：:X-ray atomic structure of recombinant Hell's gate globin I (HGbI) from Methylacidophilum infernorum was calculated from the X-ray diffraction data of two different types of crystals: obtained by classical hanging drop and by LB nanotemplate method under the same crystallization conditions. After the accurate compariso...

journal_title：Journal of cellular biochemistry

authors： Pechkova E,Scudieri D,Belmonte L,Nicolini C

更新日期：2012-07-01 00:00:00

abstract：:Interferon-τ (IFNT) is a major cytokine produced by the ruminant trophoectoderm during the peri-implantation period exerting immunomodulatory actions on various cells including neutrophils. The current in vitro study was undertaken to analyze the concentration-dependent effects of IFNT on neutrophil gene dynamics to u...

journal_title：Journal of cellular biochemistry

authors： Manjari P,Hyder I,Kapoor S,Senthilnathan M,Dang AK

更新日期：2018-12-01 00:00:00

abstract：:A homogeneous preparation of a urinary glycoprotein has been isolated from urine of patients with malignant melanoma and advanced adenocarcinomas of colon and lung. This molecule, Mr 30 kDa, is homologous to EDC1, a proteinase inhibitor antigenically related to plasma inter-alpha-trypsin inhibitor (IATI) originally is...

journal_title：Journal of cellular biochemistry

authors： Chawla RK,Lawson DH,Travis J

更新日期：1990-04-01 00:00:00

abstract：:For several decades, cholesterol has been thought to cause ASCVD. Limiting dietary cholesterol intake has been recommended to reduce the risk of the disease. However, several recent epidemiological studies do not support a relationship between dietary cholesterol and/or blood cholesterol and ASCVD. Consequently, the r...

journal_title：Journal of cellular biochemistry

authors： Huang SS,Liu IH,Chen CL,Chang JM,Johnson FE,Huang JS

更新日期：2017-06-01 00:00:00

abstract：:Intact human erythrocytes, initially depleted of Mg2+ by EDTA incubation in the presence of A23187, exhibit Mg(2+)-dependent phosphate production of around 1.5 mmol per liter cells.h, half-maximally activated at around 0.4 mM added free Mg2+. This appears to correspond to Mg(2+)-stimulated adenosine triphosphatase (Mg...

journal_title：Journal of cellular biochemistry

authors： Xu YH,Lu ZY,Conigrave AD,Auland ME,Roufogalis BD

更新日期：1991-08-01 00:00:00