Regulation of osteoclastogenesis by gap junction communication.

abstract：:Muscle progenitor cells differentiate to myoblasts, and subsequently myotubes, upon expression of muscle specific genes. We and others have previously shown that myotube nuclei, even in the absence of nerve, express AChR alpha subunit RNA at varying levels, with a small subset (about ten percent) of the nuclei express...

journal_title：Journal of cellular biochemistry

authors： Su X,Berman SA,Sullivan T,Bursztajn S

更新日期：1995-05-01 00:00:00

abstract：:Operons subject to catabolite repression (CR) in the gram-positive bacteria appear to be transcriptionally regulated by negative acting catabolite repressors. Cis elements within the promoter regions of a few CR operons have been identified as the target sequences for these repressors. It has also been proposed that s...

journal_title：Journal of cellular biochemistry

authors： Stewart GC

更新日期：1993-01-01 00:00:00

abstract：:Hepassocin (HPS) is a specific mitogenic active factor for hepatocytes, and inhibits growth by overexpression in hepatocellular carcinoma (HCC) cells. However, the mechanism of HPS regulation on growth of liver-derived cells still remains largely unknown. In this study, we found that HPS was expressed and secreted int...

journal_title：Journal of cellular biochemistry

authors： Cao MM,Xu WX,Li CY,Cao CZ,Wang ZD,Yao JW,Yu M,Zhan YQ,Wang XH,Tang LJ,Chen H,Li W,Ge CH,Yang XM

更新日期：2011-10-01 00:00:00

abstract：:Follicular thyroglobulin (TG) reflects the storage of both iodine and thyroid hormone. This is because it is a macromolecular precursor of thyroid hormone and organic iodinated compound in follicular lumen. Thus, it may have an important feedback role in thyroid function. In this study, monolayer cells were cultured a...

journal_title：Journal of cellular biochemistry

authors： Huang H,Shi Y,Lin L,Li L,Lin X,Li X,Xu D

更新日期：2011-03-01 00:00:00

abstract：:NMR spectroscopy is able to detect subtle changes to the surface chemistry of cells. We have previously shown that high-resolution 1H NMR methods can identify tumor cells with the capacity to metastasize, and we now report that the long T2 relaxation value (500-800 ms) observed in metastatic rat mammary adenocarcinoma...

journal_title：Journal of cellular biochemistry

authors： Wright LC,May GL,Gregory P,Dyne M,Holmes KT,Williams PG,Mountford CE

更新日期：1988-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:In this study, we aimed to study the molecular mechanisms underlying the symptoms of hyperresponsiveness during intubation. METHOD:The value of circulating long noncoding RNA (lncRNA)-prognosis-associated gallbladder cancer (PAGBC) in the prediction of hyperresponsiveness upon intubation duri...

journal_title：Journal of cellular biochemistry

authors： Li LX,Li YJ,He JX

更新日期：2018-09-23 00:00:00

abstract：:Several studies have shown the important actions of cytokine leptin that regulates food intake and energy expenditure. Additionally, the ability to modulate hematopoiesis has also been demonstrated. Previous reports have shown that some synthetic sequences of leptin molecules can activate leptin receptor. Herein, deca...

journal_title：Journal of cellular biochemistry

authors： Dias CC,Nogueira-Pedro A,Tokuyama PY,Martins MN,Segreto HR,Buri MV,Miranda A,Paredes-Gamero EJ

更新日期：2015-07-01 00:00:00

abstract：:Sertoli cells provide the nutritional and metabolic support for germ cells. Wnt/β-catenin signaling is important for the development of the seminiferous epithelium during embryonic age, although after birth this pathway is downregulated. Cx43 gene codes for a protein that is critical during testicular development. The...

journal_title：Journal of cellular biochemistry

authors： López C,Aguilar R,Nardocci G,Cereceda K,Vander Stelt K,Slebe JC,Montecino M,Concha II

更新日期：2019-04-01 00:00:00

abstract：:Atherosclerosis is a chronic immuno-inflammatory disease associated with blood lipids disorder. Many studies have demonstrated that caloric restriction (CR) can prevent atherosclerosis and extend lifespan. Sir2 protein, mammal's SIRT1, has been reported to at least partly contribute to the protective effect of CR. Hen...

journal_title：Journal of cellular biochemistry

authors： Yu W,Fu YC,Chen CJ,Wang X,Wang W

更新日期：2009-09-01 00:00:00

abstract：:Insulin-like growth factor I (IGF-1) is a well-established mitogen to many different cell types and is implicated in progression of a number of human cancers, notably breast cancer. The prolyl isomerase Pin1 plays an important role in cell cycle regulation through its specific interaction with proteins that are phosph...

journal_title：Journal of cellular biochemistry

authors： You H,Zheng H,Murray SA,Yu Q,Uchida T,Fan D,Xiao ZX

更新日期：2002-01-01 00:00:00

abstract：:ATF6, a 670 amino acid endoplasmic reticulum (ER) transmembrane glycoprotein with the electrophoretic mobility of a 90 kDa protein, is a key transcriptional activator of the unfolded protein response (UPR) that allows mammalian cells to maintain cellular homeostasis when the cells are subjected to a variety of environ...

journal_title：Journal of cellular biochemistry

authors： Hong M,Li M,Mao C,Lee AS

更新日期：2004-07-01 00:00:00

abstract：:The role of beta-catenin in skeletal development and osteogenic cell differentiation is well established, but the molecular mechanisms attending these effects remain largely unknown. We conducted a structure/function analysis of beta-catenin to gain further insights on these mechanisms. Retroviral transduction of a fu...

journal_title：Journal of cellular biochemistry

authors： Salazar VS,Mbalaviele G,Civitelli R

更新日期：2008-06-01 00:00:00

abstract：:Neurological disorders, such as stroke, are triggered by a loss of neurons and glial cells. Ischemic stroke remains a substantial problem for industrialized countries. Over the previous few decades our understanding about the pathophysiology of stroke has enhanced, nevertheless, more awareness is required to advance t...

journal_title：Journal of cellular biochemistry

authors： Rikhtegar R,Yousefi M,Dolati S,Kasmaei HD,Charsouei S,Nouri M,Shakouri SK

更新日期：2019-06-01 00:00:00

abstract：:Human prostatic carcinoma frequently metastasizes to bone tissue and activates bone metabolism, especially bone formation, at the site of metastasis. It has been reported that an extract of prostatic carcinoma and conditioned medium (CM) of a human prostatic carcinoma cell line, PC-3, established from a bone metastast...

journal_title：Journal of cellular biochemistry

authors： Kido J,Yamauchi N,Ohishi K,Kataoka M,Nishikawa S,Nakamura T,Kadono H,Ikedo D,Ueno A,Nonomura N,Okuyama A,Nagata T

更新日期：1997-11-01 00:00:00

abstract：:Connexin43 (Cx43) forms gap junctions that mediate intercellular communication between osteoblasts. We have examined the effects of prostaglandin E2 (PGE2) and parathyroid hormone (PTH) on gap junctional communication in the rat osteogenic sarcoma cells UMR 106-01. Incubation with either PGE2 or PTH rapidly (within 30...

journal_title：Journal of cellular biochemistry

authors： Civitelli R,Ziambaras K,Warlow PM,Lecanda F,Nelson T,Harley J,Atal N,Beyer EC,Steinberg TH

更新日期：1998-01-01 00:00:00

abstract：:Long non-coding RNAs (lncRNAs) can participate in the pathological process of multiple myeloma (MM) via regulation of specific gene expression and function. This research aimed to study the role of MALAT-1 and the underlying mechanism in MM. In this study, the expression of MALAT-1 and HMGB1 protein in the bone marrow...

journal_title：Journal of cellular biochemistry

authors： Gao D,Lv AE,Li HP,Han DH,Zhang YP

更新日期：2017-10-01 00:00:00

abstract：:The proteins of 14-3-3 family are substantially involved in the regulation of many biological processes including the apoptosis. We studied the changes in the expression of five 14-3-3 isoforms (beta, gamma, epsilon, tau, and zeta) during the apoptosis of JURL-MK1 and K562 cells. The expression level of all these prot...

journal_title：Journal of cellular biochemistry

authors： Kuzelová K,Grebenová D,Pluskalová M,Kavan D,Halada P,Hrkal Z

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Long noncoding RNA (lncRNA) is emerging as a vital regulator in various cancers. Recently, it was found that lncRNA colorectal neoplasia differentially expressed (CRNDE) plays an oncogenic role, promoting cell proliferation and migration in hepatocellular carcinoma (HCC). However, the underlying regulatory m...

journal_title：Journal of cellular biochemistry

authors： Tang D,Zhao L,Peng C,Ran K,Mu R,Ao Y

更新日期：2019-09-01 00:00:00

abstract：:Cervical cancer is one of the leading female health-killers among all types of malignancies globally. Human papillomavirus infection combined with genetic and epigenetic alterations have been indicated to be closely associated with the pathogenesis, progression, and malignant transformation of cervical cancer. Notably...

journal_title：Journal of cellular biochemistry

authors： Li C,Ke J,Liu J,Su J

更新日期：2020-03-01 00:00:00

abstract：:This review evaluates the use of temperature-sensitive (ts) mutants to investigate functional molecules in mammalian cells. A series of studies were performed in which mammalian cells expressing functional molecules were isolated from ts mutants using complementation by the introduction and expression of the responsib...

journal_title：Journal of cellular biochemistry

authors： Sugaya K

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Cholangiocarcinoma (CC) is devastating neoplasm and very few specific biomarkers could be used in clinical diagnosis. A study was taken to find novel serum biomarkers for CC. METHODS:Surface enhanced laser desorption/ionization (SELDI) technology was used to analyze 427 serum samples including 56 CCs, 49 he...

journal_title：Journal of cellular biochemistry

authors： Liu L,Wang J,Liu B,Dai S,Wang X,Chen J,Huang L,Xiao X,He D

更新日期：2008-06-01 00:00:00

abstract：:Oxoglutarate receptor 1 (OXGR1), as one of the intermediates in G protein-coupled receptors (GPCRs), plays a crucial role in the citric acid cycle receptor of α-ketoglutarate and metabolism. GPCR can control the cell proliferation by regulating the downstream signaling of G protein signaling pathways. The PI3K/AKT pat...

journal_title：Journal of cellular biochemistry

authors： Wang Q,Zhang Q,Zhang Y,Zhao X

更新日期：2019-04-01 00:00:00

abstract：:Nuclear receptor coactivator 5 (NCOA5) specifically enhances estrogen receptor α-modulated transcriptional activity. As a novel tumor suppressor, depletion of NCOA5 is associated with the development of a variety of tumors, but its function in cervical cancer is currently unclear. In this study, we addressed how expre...

journal_title：Journal of cellular biochemistry

authors： Liang Y,Zhang T,Shi M,Zhang S,Guo Y,Gao J,Yang X

更新日期：2019-04-01 00:00:00

abstract：:The active vitamin D metabolite 1,25-dihydroxyvitamin D3 [1,25-D3] is thought to promote many of its actions through interaction with a specific intracellular receptor. The discovery of such receptors in monocytes and activated lymphocytes has led investigators to evaluate the role of the hormone on the immune system....

journal_title：Journal of cellular biochemistry

authors： Lemire JM

更新日期：1992-05-01 00:00:00

abstract：:ABP50 is a polypeptide elongation factor 1 alpha from Dictyostelium that is associated with the actin cytoskeleton. Upon chemotactic stimulation, ABP50 undergoes a dramatic cytoplasmic redistribution into newly formed surface projections and in vitro binds to and bundles actin filaments. Many questions are raised by t...

journal_title：Journal of cellular biochemistry

authors： Edmonds BT

更新日期：1993-06-01 00:00:00

abstract：:4-hydroxynonenal (HNE), a lipid peroxidation end product, is produced abundantly in osteoarthritic (OA) articular tissues and was recently identified as a potent catabolic factor in OA cartilage. In this study, we provide additional evidence that HNE acts as an inflammatory mediator by elucidating the signaling cascad...

journal_title：Journal of cellular biochemistry

authors： Vaillancourt F,Morquette B,Shi Q,Fahmi H,Lavigne P,Di Battista JA,Fernandes JC,Benderdour M

更新日期：2007-04-01 00:00:00

abstract：:Up-regulation of cytosolic phospholipase A(2) (cPLA(2)) by cigarette smoke extract (CSE) may play a critical role in airway inflammatory diseases. However, the mechanisms underlying CSE-induced cPLA(2) expression in human tracheal smooth muscle cells (HTSMCs) were not completely understood. Here, we demonstrated that ...

journal_title：Journal of cellular biochemistry

authors： Cheng SE,Lin CC,Lee IT,Hsu CK,Kou YR,Yang CM

更新日期：2011-02-01 00:00:00

abstract：:Although activated macrophages destroy cancer cells more effectively than normal cells, the ability to escape activated macrophages is a characteristic of tumor cells. One of the mechanisms responsible for the specific killing of tumor cells by macrophages is the production of the cytokine tumor necrosis factor (TNF) ...

journal_title：Journal of cellular biochemistry

authors： Guijarro MV,Castro ME,Romero L,Moneo V,Carnero A

更新日期：2007-05-01 00:00:00

abstract：:We have previously characterized the expression of the alpha nu beta 5 and alpha nu beta 6 integrins as major receptors for the human colonic adenocarcinoma cell line (HT29-D4), on vitronectin and fibronectin, respectively [Lehmann et al. (1994): Cancer Res 54:2102-2107]. In the present work we investigated the glycos...

journal_title：Journal of cellular biochemistry

authors： Lehmann M,El Battari A,Abadie B,Martin JM,Marvaldi J

更新日期：1996-05-01 00:00:00

abstract：:The vitamin D receptor (VDR) binds to and mediates the effects of the 1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) hormone to alter gene transcription. A newly recognized VDR ligand is the carcinogenic bile acid, lithocholic acid (LCA). We demonstrate that, in HT-29 colon cancer cells, both LCA and 1,25(OH)(2)D(3) ind...

journal_title：Journal of cellular biochemistry

authors： Jurutka PW,Thompson PD,Whitfield GK,Eichhorst KR,Hall N,Dominguez CE,Hsieh JC,Haussler CA,Haussler MR

更新日期：2005-04-01 00:00:00