Shift-and-Persist Strategies: Associations With Socioeconomic Status and the Regulation of Inflammation Among Adolescents and Their Parents.

Abstract:

OBJECTIVE:Shift-and-persist is a resilience construct hypothesized to be beneficial to physical health among individuals with low socioeconomic status (SES). This shift-and-persist construct entails a combination of reframing stressors more positively while also enduring adversity through finding purpose in life. In this study, we investigated how shift-and-persist relates to key inflammatory processes that are implicated in cardiovascular and other diseases. We also obtained validation information on a new shift-and-persist measure. METHOD:A sample of 122 adolescents and 122 parents from a diverse range of SES backgrounds completed our shift-and-persist measure, a battery of other psychosocial questionnaires and interviews, and provided blood samples. Parents also provided SES information. RESULTS:Reliability and validity of the shift-and-persist measure were demonstrated across both adolescents and adults. Shift-and-persist moderated the association between SES and indicators of inflammatory regulation. Specifically, as SES declined, shift-and-persist was associated with greater sensitivity to glucocorticoids' anti-inflammatory properties (interaction in adolescents: [beta] = .21, p = .033; interaction in adults: [beta] = .25, p = .011), and also with less low-grade, chronic inflammation (interaction in adolescents: [beta] = .18, p = .044). Conversely, as SES increased, the opposite pattern was evident. CONCLUSIONS:These findings suggest that adaptive psychosocial characteristics have the potential to regulate inflammatory processes in ways that may mitigate risk for a number of chronic diseases, particularly among disadvantaged groups.

journal_name

Psychosom Med

journal_title

Psychosomatic medicine

authors

Chen E,McLean KC,Miller GE

doi

10.1097/psy.0000000000000157

subject

Has Abstract

pub_date

2015-05-01 00:00:00

pages

371-82

issue

4

eissn

0033-3174

issn

1534-7796

journal_volume

77

pub_type

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