Treatment of somatoform disorders with St. John's wort: a randomized, double-blind and placebo-controlled trial.

abstract：OBJECTIVE:To test the hypothesis that increased levels of inflammatory and hemostatic markers are associated with poorer cognitive performance and to assess the influence of childhood intelligence quotient (IQ) and current cardiovascular disease (CVD) risk factors on this relationship. Blood inflammatory markers have b...

journal_title：Psychosomatic medicine

authors： Luciano M,Marioni RE,Gow AJ,Starr JM,Deary IJ

更新日期：2009-05-01 00:00:00

abstract：:The peripheral decarboxylase inhibitor carbidopa (L-alphamethyl-dopa-hydrazine) allowed safe intravenous administration of L-DOPA in amounts sufficient to alter cortical average evoked response (AER) and learning function in 13 depressed patients. The apparently rapid conversion of L-DOPA to dopamine, as reported from...

journal_title：Psychosomatic medicine

authors： Henry GM,Buchsbaum M,Murphy DL

更新日期：1976-03-01 00:00:00

abstract：OBJECTIVE:To assess whether globus is associated with psychopathology in men. Globus-a persistent sensation of having a lump in the throat with no detectable physical cause-has long been thought a predominantly female disorder. Several small studies, based wholly or largely on women, suggested that globus is associated...

journal_title：Psychosomatic medicine

authors： Gale CR,Wilson JA,Deary IJ

更新日期：2009-11-01 00:00:00

abstract：OBJECTIVE:Altered autonomic nervous system activity is considered to be involved in the pathophysiology of somatic symptom disorder (SSD). This study aimed to investigate whether patients with SSD have disturbed autonomic activity during rest and reactivity to emotional processing and whether altered autonomic nervous ...

journal_title：Psychosomatic medicine

authors： Lee D,Kim SJ,Cheon J,Hwang EH,Jung YC,Kang JI

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVES:To document changes in Axis I psychiatric disorders after bariatric surgery and examine their relationship with postsurgery weight loss. METHODS:As part of a three-site substudy of the Longitudinal Assessment of Bariatric Surgery Research Consortium, 199 patients completed the Structured Clinical Interview ...

journal_title：Psychosomatic medicine

authors： Kalarchian MA,King WC,Devlin MJ,Marcus MD,Garcia L,Chen JY,Yanovski SZ,Mitchell JE

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:Previous research suggests that psychosocial job stressors may be plausible risk factors for suicide. This study assessed the relationship between psychosocial job stressors and suicide mortality across the Australian population. METHODS:We developed a job exposure matrix to objectively measure job stressors...

journal_title：Psychosomatic medicine

authors： Milner A,Spittal MJ,Pirkis J,Chastang JF,Niedhammer I,LaMontagne AD

更新日期：2017-04-01 00:00:00

abstract：OBJECTIVE:Depression and coronary heart disease (CHD) are comorbid conditions, and it is thought that depression may increase the risk of CHD. However, the evidence for the latter relationship is sparse and difficult to collect. Cynomolgus monkeys (Macaca fascicularis) have been used effectively as animal models of CHD...

journal_title：Psychosomatic medicine

authors： Shively CA,Williams JK,Laber-Laird K,Anton RF

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVE:This study investigates psychological and psychobiological processes in patients with somatization syndrome. METHOD:We compared physiological measures (heart rate, finger pulse volume, electrodermal activity, electromyography), cortisol levels, and subjective well-being during rest and during a mental stress...

journal_title：Psychosomatic medicine

authors： Rief W,Shaw R,Fichter MM

更新日期：1998-03-01 00:00:00

abstract：OBJECTIVES:Our objectives were to test whether Conscientiousness, the other 4 domains of the Five-Factor Model, and their facets predicted mortality in older, frail individuals. METHODS:Controlling for demographic and health measures, we used Cox regression to test whether the NEO Five-Factor Inventory (NEO-FFI) Neuro...

journal_title：Psychosomatic medicine

authors： Weiss A,Costa PT Jr

更新日期：2005-09-01 00:00:00

abstract：:Growth of syngeneic P815 mastocytoma in DBA/2J male mice was evaluated following social and physical stress exposure. Although social isolation following tumor cell transplantation enhanced tumor growth, it appeared that it was the abrupt change in social conditions, rather than the isolation per se which was responsi...

journal_title：Psychosomatic medicine

authors： Sklar LS,Anisman H

更新日期：1980-05-01 00:00:00

abstract：OBJECTIVE:To determine whether the relationship between interleukin (IL)-6 and depressive symptoms is moderated by participation in moderate-intensity physical activity in a sample of primary care patients. Elevated inflammation has been associated with a number of poor health outcomes. Depressive symptoms may be relat...

journal_title：Psychosomatic medicine

authors： Rethorst CD,Moynihan J,Lyness JM,Heffner KL,Chapman BP

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:The new DSM-5 somatic symptom disorder was introduced to improve the diagnosis of persons experiencing what used to be called somatoform disorders. So far, it is unclear whether existing self-report measures are useful to detect the new somatic symptom disorder. This study investigates the diagnostic accuracy...

journal_title：Psychosomatic medicine

authors： Laferton JAC,Stenzel NM,Rief W,Klaus K,Brähler E,Mewes R

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:Influenza and pneumonia account for significant morbidity and mortality, particularly in older individuals. Previous studies have shown that spousal caregivers of patients with dementia have poorer antibody and virus specific T cell responses to an influenza virus vaccine relative to noncaregiving control sub...

journal_title：Psychosomatic medicine

authors： Glaser R,Sheridan J,Malarkey WB,MacCallum RC,Kiecolt-Glaser JK

更新日期：2000-11-01 00:00:00

abstract：OBJECTIVE:This article provides the chemical basis for the molecular modification of H1 antihistamines in the rational development of some antidepressant and antipsychotic drugs. METHODS:A review of the literature and personal experiences have been compiled. CONCLUSIONS:The contributions of many basic scientists, the...

journal_title：Psychosomatic medicine

authors： Domino EF

更新日期：1999-09-01 00:00:00

abstract：OBJECTIVE:A model for the development of anxiety disorders (panic disorder with or without agoraphobia) is needed. Patients with an implantable cardioverter/defibrillator (ICD) are exposed to repeated electric shocks. If the theory of anxiety development by aversive classic conditioning processes is valid, these repeat...

journal_title：Psychosomatic medicine

authors： Godemann F,Ahrens B,Behrens S,Berthold R,Gandor C,Lampe F,Linden M

更新日期：2001-03-01 00:00:00

abstract：:The development of seven esophageal atresia infants is described. These children differed in the quality of maternal care received and the amount of oral experience permitted during the first year of life. Observation of these infants suggest differences between effects of maternal depression and effects of abnormal o...

journal_title：Psychosomatic medicine

authors： Dowling S

更新日期：1980-01-01 00:00:00

abstract：:The personality patterns of cancer patients as found in retrospective case-control studies are often suspected to be consequences of the disease. In this study an attempt was made to remove the bias arising from the disease itself by taking into account two indicator variables for the subject's anticipation of the sub...

journal_title：Psychosomatic medicine

authors： Scherg H

更新日期：1987-05-01 00:00:00

abstract：:Earlier studies suggest that cardiovascular responses in the laboratory and in the field are likely to be related when the laboratory tasks involve active coping, when the field measure is taken continuously, and when there is allowance for the effects of autocorrelation and physical activity on the ambulant cardiovas...

journal_title：Psychosomatic medicine

authors： Johnston DW,Schmidt TF,Albus C,Vagt S,McSorley K,Klingmann I,Bethge H

更新日期：1994-07-01 00:00:00

abstract：OBJECTIVE:To investigate the association between vitamin D deficiency and depressive symptoms in a national community sample of older people. Vitamin D deficiency is common in older people with potential effects on mood. METHODS:Data were analyzed from 2070 participants aged ≥65 years who had participated in the 2005 ...

journal_title：Psychosomatic medicine

authors： Stewart R,Hirani V

更新日期：2010-09-01 00:00:00

abstract：:Plasma levels of luteinizing hormone (LH) and testosterone were determined by radioimmunoassay in medical students just before (Exp. 1) and after (Exp. 2) an academic examination and corresponding control periods. Before the examination (Exp. 1), the males' LH values were lower than their control levels, but there was...

journal_title：Psychosomatic medicine

authors： Johansson GG,Laakso ML,Peder M,Karonen SL

更新日期：1988-05-01 00:00:00

abstract：OBJECTIVE:Numerous theories have proposed that acute and chronic stressors may exert a cumulative effect on life-span health by causing biological "wear and tear," or allostatic load, which in turn promotes disease. Very few studies have directly tested such models, though, partly because of the challenges associated w...

journal_title：Psychosomatic medicine

authors： Slavich GM,Shields GS

更新日期：2018-01-01 00:00:00

abstract：:A sample of 45 patients with a history of coronary heart disease and documented myocardial ischemia during exercise testing were evaluated in an investigation of the possible relationships between psychological factors (depression and Type A behavior pattern), plasma beta-endorphin response and pain experience during ...

journal_title：Psychosomatic medicine

authors： Light KC,Herbst MC,Bragdon EE,Hinderliter AL,Koch GG,Davis MR,Sheps DS

更新日期：1991-11-01 00:00:00

abstract：:In this industrial-based study we compared the blood pressure (BP)-lowering effectiveness of relaxation, a beta blocker, and the combined use of these two treatments in 47 untreated, mildly hypertensive blue collar steel workers. Using a randomized two by two factorial design, patients received either nadolol or place...

journal_title：Psychosomatic medicine

authors： Adsett CA,Bellissimo A,Mitchell A,Wilczynski N,Haynes RB

更新日期：1989-09-01 00:00:00

abstract：OBJECTIVE:An attachment model was used to understand how maternal sensitivity and adverse childhood experiences are related to somatization. METHODS:We examined maternal sensitivity at 6 and 18 months and somatization at 5 years in 292 children in a longitudinal cohort study. We next examined attachment insecurity and...

journal_title：Psychosomatic medicine

authors： Maunder RG,Hunter JJ,Atkinson L,Steiner M,Wazana A,Fleming AS,Moss E,Gaudreau H,Meaney MJ,Levitan RD

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVE:Biochemical host defenses at mucosal sites, such as the oral cavity, play a key role in the regulation of microbial ecology and the prevention of infectious disease. These biochemical factors have distinct features, some of which benefit the host and some that benefit bacteria. We investigated the effects of ...

journal_title：Psychosomatic medicine

authors： Bosch JA,de Geus EJ,Ligtenberg TJ,Nazmi K,Veerman EC,Hoogstraten J,Amerongen AV

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:Autonomic nervous system activity is associated with neurobehavioral aspects of pain. Yogis use breathing, relaxation, and mindfulness to tolerate pain, which could influence autonomic responses. To evaluate how the link between autonomic responses and pain is altered by other factors, we compared perceptual ...

journal_title：Psychosomatic medicine

authors： Cotton VA,Low LA,Villemure C,Bushnell MC

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to examine the association between psychobiological stress reactivity during healthy pregnancy and depressive symptoms in the early puerperium. METHODS:A sample of healthy nulliparous pregnant women (N = 57) between the ages of 21 and 35 years underwent a standardized psychosoci...

journal_title：Psychosomatic medicine

authors： Nierop A,Bratsikas A,Zimmermann R,Ehlert U

更新日期：2006-11-01 00:00:00

abstract：OBJECTIVE:Little is known about how patients who seek medical help for benign palpitations can be distinguished from those with clinically significant arrhythmias. This study tested whether patients with arrhythmia can be distinguished from those who are aware of sinus rhythm or extrasystoles on the basis of sex, preva...

journal_title：Psychosomatic medicine

authors： Ehlers A,Mayou RA,Sprigings DC,Birkhead J

更新日期：2000-09-01 00:00:00

abstract：:This study's purpose was to examine the extent to which optimism, knowledge, attitudes, and beliefs predict use of HIV testing services in a group of at-risk female adolescents. We prospectively interviewed 124 consecutive girls engaging in risky behaviors before regularly scheduled pediatric clinic appointments at a ...

journal_title：Psychosomatic medicine

authors： Goodman E,Chesney MA,Tipton AC

更新日期：1995-11-01 00:00:00

abstract：OBJECTIVES:To examine associations between intelligence and psychomotor coordination in childhood and risk of psychological distress, poorer self-rated health, and obesity in adulthood. To investigate whether psychomotor coordination as a potential marker of the construct "system integrity" explains associations betwee...

journal_title：Psychosomatic medicine

authors： Gale CR,Batty GD,Cooper C,Deary IJ

更新日期：2009-07-01 00:00:00