Individualized prediction of psychosis in subjects with an at-risk mental state.

abstract：:Social perception and mentalizing are fundamental social cognitive abilities that are related to functioning and are impaired in schizophrenia. A novel approach to examine the relationship between social cognition and community functioning is to first functionally categorize individuals with schizophrenia and then eva...

journal_title：Schizophrenia research

authors： Karpouzian TM,Alden EC,Reilly JL,Smith MJ

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVE:Attentional deficits represent a core cognitive impairment in schizophrenia. The distractor condition Sustained Attention Task (dSAT) has been identified by the Cognitive Neuroscience Treatment to Improve Cognition in Schizophrenia (CNTRICS) initiative as a promising translational task for assessing schizophr...

journal_title：Schizophrenia research

authors： Demeter E,Guthrie SK,Taylor SF,Sarter M,Lustig C

更新日期：2013-03-01 00:00:00

abstract：:Fragile X mental retardation protein (FMRP) is an RNA binding protein with 842 target mRNAs in mammalian brain. Silencing of the fragile X mental retardation 1 (FMR1) gene leads to loss of expression of FMRP and upregulated metabotropic glutamate receptor 5 (mGluR5) signaling resulting in the multiple physical and cog...

journal_title：Schizophrenia research

authors： Folsom TD,Thuras PD,Fatemi SH

更新日期：2015-07-01 00:00:00

abstract：:Schizophrenia has generally been viewed as having a unique preschizophrenia personality or destructive to the personality post-onset. This view is reflected in the scarcity of studies of personality in schizophrenia with the exception of schizotypal personality considered by many as an endophenotype of schizophrenia. ...

journal_title：Schizophrenia research

authors： Lewine R,Martin M,Hart M

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Gamma-aminobutyric acid (GABA) dysfunction and its consequent imbalance are implicated in the pathophysiology of schizophrenia. Reduced GABA production would lead to a disinhibition of glutamatergic neurons and subsequently cause a disruption of the modulation between GABAergic interneurons and glutamatergic...

journal_title：Schizophrenia research

authors： Chiu PW,Lui SSY,Hung KSY,Chan RCK,Chan Q,Sham PC,Cheung EFC,Mak HKF

更新日期：2018-03-01 00:00:00

abstract：:Eleven acutely psychotic patients with schizophrenia or schizoaffective disorder underwent a 5-7 day drug-washout period (with lorazepam allowed) prior to participating in a 6-week controlled dose haloperidol trial. Patients were evaluated longitudinally with clinical ratings and with plasma measures of the catecholam...

journal_title：Schizophrenia research

authors： Green AI,Alam MY,Boshes RA,Waternaux C,Pappalardo KM,Fitzgibbon ME,Tsuang MT,Schildkraut JJ

更新日期：1993-06-01 00:00:00

abstract：:The immune hypothesis of schizophrenia has gained significant popularity in recent years in schizophrenia research. Evidence suggests that the peripheral immune system communicates with central nervous system and the effect propagates through microglial and lymphocyte crosstalk, especially during neuro-inflammation. A...

journal_title：Schizophrenia research

authors： Varun CN,Venkataswamy MM,Ravikumar R,Nagaraju R,Debnath M,Varambally S,Venkatasubramanian G,Ravi V

更新日期：2019-10-01 00:00:00

abstract：:Psychiatric case records from Eaton and Weil's 1950-53 study of the Hutterites were rediagnosed using DSM-III-R criteria. The results confirmed that the Hutterites have a very low prevalence of both schizophrenia (0.9 per 1000) and bipolar disorder (0.6 per 1000). Genetic and/or environmental explanations are both pos...

journal_title：Schizophrenia research

authors： Torrey EF

更新日期：1995-08-01 00:00:00

abstract：:Jumping to conclusions (JTC) is the best established cognitive bias in schizophrenia and is increasingly targeted in interventions aimed to improve positive symptoms. To address shortcomings of the standard measure to capture JTC, the beads task, we developed a new variant-the box task-which was subsequently validated...

journal_title：Schizophrenia research

authors： Moritz S,Scheunemann J,Lüdtke T,Westermann S,Pfuhl G,Balzan RP,Andreou C

更新日期：2020-08-01 00:00:00

abstract：:Up to 50-90% of persons with schizophrenia smoke cigarettes. Limited data and theories suggest persons with schizophrenia may smoke for different reasons than persons without schizophrenia, making smoking cessation interventions particularly challenging in this population. Although health consequences of smoking are w...

journal_title：Schizophrenia research

authors： Wehring HJ,Liu F,McMahon RP,Mackowick KM,Love RC,Dixon L,Kelly DL

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVE:Neuregulin-1 (NRG1) has been put forward as a susceptibility gene for schizophrenia. We investigated the association between Neuregulin-1 and the P300 wave, a schizophrenia endophenotype. METHODS:Participants were 64 patients with DSM-IV schizophrenia or schizoaffective disorder, 97 of their non psychotic re...

journal_title：Schizophrenia research

authors： Bramon E,Dempster E,Frangou S,Shaikh M,Walshe M,Filbey FM,McDonald C,Sham P,Collier DA,Murray R

更新日期：2008-08-01 00:00:00

abstract：:Verbal dichotic listening performance was examined in 42 right-handed men and women with DSM-IV-defined schizotypal personality disorder (SPD) and 68 right-handed controls. As expected, both male and female control groups showed a right ear advantage on a verbal dichotic listening task. Although SPD subjects in genera...

journal_title：Schizophrenia research

authors： Voglmaier MM,Seidman LJ,Niznikiewicz MA,Madan A,Dickey CC,Shenton ME,McCarley RW

更新日期：2009-12-01 00:00:00

abstract：:Frontal lobe dysfunction in individuals with schizophrenia has frequently been detected using both neuroimaging and neuropsychological testing. Results from previous studies vary in the findings of regional specificity vs. generalized frontal cortical dysfunction. We sought to examine potential regional differences in...

journal_title：Schizophrenia research

authors： Ritter LM,Meador-Woodruff JH,Dalack GW

更新日期：2004-05-01 00:00:00

abstract：:Schizophrenia is associated with subtle developmental compromise, but the degree to which this is also associated with heritability and genetic risk is uncertain. The goal of the current study was to investigate the childhood, adolescent, and early adulthood social and academic function of patients with schizophrenia,...

journal_title：Schizophrenia research

authors： Shapiro DI,Marenco S,Spoor EH,Egan MF,Weinberger DR,Gold JM

更新日期：2009-07-01 00:00:00

abstract：:Estrogen has been shown in animal studies to modulate both the dopamine and serotonin neurotransmitter systems - the main neurotransmitters implicated in the pathogenesis of schizophrenia. A double blind, 28 day, placebo-controlled study was conducted with three groups of women of child-bearing age (N=12 in each group...

journal_title：Schizophrenia research

authors： Kulkarni J,Riedel A,de Castella AR,Fitzgerald PB,Rolfe TJ,Taffe J,Burger H

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND:Eye movement abnormalities have been identified in schizophrenia; however, their relevance to cognition is still unknown. In this study, we explored the general relationship between eye movements and cognitive function. METHODS:The three eye movement measures (scanpath length, horizontal position gain, and ...

journal_title：Schizophrenia research

authors： Morita K,Miura K,Fujimoto M,Yamamori H,Yasuda Y,Kudo N,Azechi H,Okada N,Koshiyama D,Ikeda M,Kasai K,Hashimoto R

更新日期：2019-07-01 00:00:00

abstract：:The purpose of the study was to examine the relationship between social anxiety and social functioning in first episode psychosis, and to determine whether those with psychosis have any maladaptive or irrational beliefs regarding social situations. A sample of 60 first episode patients (41 males, 19 females) participa...

journal_title：Schizophrenia research

authors： Voges M,Addington J

更新日期：2005-07-15 00:00:00

abstract：:Affect perception has frequently been shown to be impaired in patients suffering from schizophrenia or bipolar disorder (BD), but it remains unclear whether these impairments exist during symptomatic remission and whether the two disorders differ from each other in this regard. Most previous studies have investigated ...

journal_title：Schizophrenia research

authors： Hoertnagl CM,Yalcin-Siedentopf N,Baumgartner S,Biedermann F,Deisenhammer EA,Hausmann A,Kaufmann A,Kemmler G,Mühlbacher M,Rauch AS,Fleischhacker WW,Hofer A

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Higher liability to psychosis is associated with low self-esteem and increased sensitivity to social stress. Recently, we reported a positive relation between liability to psychosis and affective and psychotic responses to social stress. This study investigated how self-esteem moderates paranoia, peak subjec...

journal_title：Schizophrenia research

authors： Jongeneel A,Pot-Kolder R,Counotte J,van der Gaag M,Veling W

更新日期：2018-12-01 00:00:00

abstract：:Omega-3 treatment studies for multi-episode schizophrenia or clinical high risk for conversion to psychosis states have had variable, and often negative, results. To examine adjunctive omega-3 treatment for recent onset psychosis, participants aged 15-40 years with recent onset schizophrenia-spectrum (n = 46) or bipol...

journal_title：Schizophrenia research

authors： Robinson DG,Gallego JA,John M,Hanna LA,Zhang JP,Birnbaum ML,Greenberg J,Naraine M,Peters BD,McNamara RK,Malhotra AK,Szeszko PR

更新日期：2019-02-01 00:00:00

abstract：:Although a substance use disorder (SUD) is traditionally associated with psycho-bio-social impairments, recent investigations among persons with schizophrenia (Sz) generated divergent results. Certain persons with Sz+SUD might in fact present better social and cognitive functioning than persons with Sz without SUD. Th...

journal_title：Schizophrenia research

authors： Potvin S,Joyal CC,Pelletier J,Stip E

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:The normal vasodilatory response to ingestion of nicotinic acid (NA) is impaired in some patients with schizophrenia. It is unclear whether the impairment is a feature of the disorder itself or to a confounding factor such as neuroleptics, caffeine or nicotine use. METHODS:To address this question in a cont...

journal_title：Schizophrenia research

authors： Turenne SD,Seeman M,Ross BM

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:Higher cognitive dysfunction, lower perceptual disturbance and its relation to the structures that implicate such processes have been considered as key features in patients with schizophrenia. However, little is known about the relationship between perceptual processing and structural deficits in ultra-high-...

journal_title：Schizophrenia research

authors： Shin KS,Jung WH,Kim JS,Jang JH,Hwang JY,Chung CK,Kwon JS

更新日期：2012-09-01 00:00:00

abstract：:Earlier studies suggest that social competence has a higher predictive value for vocational outcome than psychopathology. These studies, however, show methodological shortcomings, including the fact that the instruments used for assessing social competence, psychopathology and work performance are strongly interrelate...

journal_title：Schizophrenia research

authors： Hoffmann H,Kupper Z

更新日期：1997-01-17 00:00:00

abstract：OBJECTIVE:The Recovery Assessment Scale (RAS) is one of the most widely used measurements of recovery in mental health research. To date, no data have been available concerning the psychometric characteristics of the RAS in homeless people with severe mental illness. The aim of this study was to provide new data regard...

journal_title：Schizophrenia research

authors： Girard V,Tinland A,Mohamed EH,French Housing First Study Group.,Boyer L,Auquier P

更新日期：2015-12-01 00:00:00

abstract：:Schizophrenia typically results in reduced performance on the Wisconsin Card Sorting Test (WCST). In the current study, we used a variety of approaches to examine the role of working memory (WM) in this deficit. One approach was to examine patterns of perseverative and non-perseverative errors. A second approach invol...

journal_title：Schizophrenia research

authors： Hartman M,Steketee MC,Silva S,Lanning K,Andersson C

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:Deficient mirror neuron system (MNS)-activity is associated with social cognition deficits in schizophrenia. However, it is not known how socio-emotional contexts modulate the MNS-response. In a Transcranial Magnetic Stimulation (TMS)-experiment, we aimed to compare putative MNS-responses to action observati...

journal_title：Schizophrenia research

authors： Bagewadi VI,Mehta UM,Naik SS,Govindaraj R,Varambally S,Arumugham SS,Naveen Kumar C,Thirthalli J

更新日期：2019-02-01 00:00:00

abstract：:Diminished expression is a diagnostic feature of a range of schizophrenia-spectrum disorders/conditions and is often unresponsive to treatment, is present across premorbid, first episode and various clinical states, and is considered a poor prognostic indicator. Surprisingly, little is known about diminished expressio...

journal_title：Schizophrenia research

authors： Cohen AS,Morrison SC,Callaway DA

更新日期：2013-08-01 00:00:00

abstract：:We investigated the relationship between the P300, neuropsychological test performance and symptomatology in recent-onset schizophrenic patients (n = 45) to gain insight into underlying mechanisms of abnormal P300 in schizophrenia. The P300 was recorded in two sessions with an intermission of five minutes, at the midl...

journal_title：Schizophrenia research

authors： Nieman DH,Koelman JH,Linszen DH,Bour LJ,Dingemans PM,Ongerboer de Visser BW

更新日期：2002-05-01 00:00:00

abstract：:This study assessed visuospatial attention in healthy adults and medicated schizophrenic patients. Participants performed a visual orientation task in which a peripheral cue was followed. at different intervals, by a target presented either at valid or invalid locations. When the long stimulus onset asynchrony (SOA) w...

journal_title：Schizophrenia research

authors： Fuentes LJ,Boucart M,Alvarez R,Vivas AB,Zimmerman MA

更新日期：1999-11-09 00:00:00