Beyond phage display: non-traditional applications of the filamentous bacteriophage as a vaccine carrier, therapeutic biologic, and bioconjugation scaffold.

abstract：:Protein phosphorylation, one of the most important post-translational modifications, regulates almost every cellular process. Although signal transduction by protein phosphorylation is extensively studied in Eukaryotes and Bacteria, the knowledge of this process in archaea is greatly lagging behind, especially for Ser...

journal_title：Frontiers in microbiology

authors： Huang Q,Zhong Q,Mayaka JBA,Ni J,Shen Y

更新日期：2017-11-07 00:00:00

abstract：:Although the mechanisms that precisely time initiation of chromosome replication in bacteria remain unclear, most clock models are based on accumulation of the active initiator protein, DnaA-ATP. During each cell division cycle, sufficient DnaA-ATP must become available to interact with a distinct set of low affinity ...

journal_title：Frontiers in microbiology

authors： Rao P,Rozgaja TA,Alqahtani A,Grimwade JE,Leonard AC

更新日期：2018-07-26 00:00:00

abstract：:H9N2 avian influenza virus is a zoonotic agent with a broad host range that can contribute genetic information to H5 or H7N9 subtype viruses, which are significant threats to both humans and birds. Thus, there is a great need for a vaccine to control H9N2 avian influenza. Three mutant viruses of an H9N2 virus A/chicke...

journal_title：Frontiers in microbiology

authors： Chen S,Zhu Y,Yang D,Yang Y,Shi S,Qin T,Peng D,Liu X

更新日期：2017-06-14 00:00:00

abstract：:The multidomain (B-NG) protein FlhF, a flagellar biogenesis regulator in several bacteria, is the third paralog of the signal recognition particle (SRP)-GTPases Ffh and FtsY, which are known to drive protein-delivery to the plasma membrane. Previously, we showed that FlhF is required for Bacillus cereus pathogenicity ...

journal_title：Frontiers in microbiology

authors： Mazzantini D,Fonnesu R,Celandroni F,Calvigioni M,Vecchione A,Mrusek D,Bange G,Ghelardi E

更新日期：2020-05-06 00:00:00

abstract：:Intertidal microbial mats are comprised of distinctly colored millimeter-thick layers whose communities organize in response to environmental gradients such as light availability, oxygen/sulfur concentrations, and redox potential. Here, slight changes in depth correspond to sharp niche boundaries. We explore the patte...

journal_title：Frontiers in microbiology

authors： Armitage DW,Gallagher KL,Youngblut ND,Buckley DH,Zinder SH

更新日期：2012-08-10 00:00:00

abstract：:Acetate is a characteristic by-product of Escherichia coli K-12 growing in batch cultures with glucose, both under aerobic as well as anaerobic conditions. While the reason underlying aerobic acetate production is still under discussion, during anaerobic growth acetate production is important for ATP generation by sub...

journal_title：Frontiers in microbiology

authors： Schütze A,Benndorf D,Püttker S,Kohrs F,Bettenbrock K

更新日期：2020-02-21 00:00:00

abstract：:The use of antibiotic agents as growth promoters was banned in animal husbandry to prevent the selection and spread of antibiotic resistance. However, in addition to antibiotic agents, heavy metals used in animal farming and aquaculture might promote the spread of antibiotic resistance via co-selection. To investigate...

journal_title：Frontiers in microbiology

authors： Seiler C,Berendonk TU

更新日期：2012-12-14 00:00:00

abstract：:Toxoplasma gondii is responsible for causing toxoplasmosis, one of the most prevalent zoonotic parasitoses worldwide. The mechanisms that mediate T. gondii infection of pigs (the most common source of human infection) and renal tissues are still unknown. To identify the critical alterations that take place in the tran...

journal_title：Frontiers in microbiology

authors： Zhou CX,Elsheikha HM,Zhou DH,Liu Q,Zhu XQ,Suo X

更新日期：2016-05-13 00:00:00

abstract：:Salar de Huasco, defined as a polyextreme environment, is a high altitude saline wetland in the Chilean Altiplano (3800 m.a.s.l.), permanently exposed to the highest solar radiation doses registered in the world. We present here the first comparative proteomics study of a photoheterotrophic bacterium, Rhodobacter sp.,...

journal_title：Frontiers in microbiology

authors： Pérez V,Hengst M,Kurte L,Dorador C,Jeffrey WH,Wattiez R,Molina V,Matallana-Surget S

更新日期：2017-06-26 00:00:00

abstract：:Soil bacterial communities have long been recognized as important ecosystem components, and have been the focus of many local and regional studies. However, there is a lack of data at large spatial scales, on the biodiversity of soil microorganisms; national or more extensive studies to date have typically consisted o...

journal_title：Frontiers in microbiology

authors： Hermans SM,Buckley HL,Lear G

更新日期：2019-08-07 00:00:00

abstract：:Fusarium sacchari and Fusarium andiyazi are two devastating sugarcane pathogens that cause pokkah boeng disease (PBD) in China. RNA_Seq was conducted to identify mycoviruses in F. sacchari and F. andiyazi isolates collected from PBD symptom-showing sugarcane plants across China. Fifteen isolates with a normal, debilit...

journal_title：Frontiers in microbiology

authors： Yao Z,Zou C,Peng N,Zhu Y,Bao Y,Zhou Q,Wu Q,Chen B,Zhang M

更新日期：2020-02-19 00:00:00

abstract：:For tolerating extreme desiccation, cyanobacteria are known to produce both compatible solutes at intracellular level and a copious amount of exopolysaccharides as a protective coat. However, these molecules make cyanobacterial cells refractory to a broad spectrum of cell disruption methods, hindering genome sequencin...

journal_title：Frontiers in microbiology

authors： Urrejola C,Alcorta J,Salas L,Vásquez M,Polz MF,Vicuña R,Díez B

更新日期：2019-05-07 00:00:00

abstract：:RNA-based vaccine represents an irresistible and safe immunization strategy with decreasing theoretical risks of genomic integration and malignant cell transformation. To our knowledge, however, there is no report about development of RNA vaccine against Toxoplasma gondii infection. We have previously demonstrated tha...

journal_title：Frontiers in microbiology

authors： Luo F,Zheng L,Hu Y,Liu S,Wang Y,Xiong Z,Hu X,Tan F

更新日期：2017-04-05 00:00:00

abstract：:Hepatitis C virus (HCV) infection involves a variety of viral and host factors, some of which promote the infection process. A small nucleolar RNA, C/D box 126 (SNORD126), was previously shown to be associated with hepatocellular carcinoma (HCC). However, the role of SNORD126 in HCV infection, which is one of the prim...

journal_title：Frontiers in microbiology

authors： Qian X,Xu C,Wu B,Tang H,Zhao P,Qi Z

更新日期：2020-09-15 00:00:00

abstract：:In filamentous fungi such as Fusarium graminearum, disruption of multiple genes of interest in the same strain (e.g., to test for redundant gene function) is a difficult task due to the limited availability of reliable selection markers. We have created a series of transformation vectors that allow antibiotic-based se...

journal_title：Frontiers in microbiology

authors： Twaruschek K,Spörhase P,Michlmayr H,Wiesenberger G,Adam G

更新日期：2018-09-11 00:00:00

abstract：:Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus, has emerged as a global pandemic worldwide. In this study, we used ARTIC primers-based amplicon sequencing to profile 225 SARS-CoV-2 genomes from India. Phylogenetic analysis of 202 high-quality assem...

journal_title：Frontiers in microbiology

authors： Raghav S,Ghosh A,Turuk J,Kumar S,Jha A,Madhulika S,Priyadarshini M,Biswas VK,Shyamli PS,Singh B,Singh N,Singh D,Datey A,Avula K,Smita S,Sabat J,Bhattacharya D,Kshatri JS,Vasudevan D,Suryawanshi A,Dash R,Senapati

更新日期：2020-11-23 00:00:00

abstract：:An ideal DNA polymerase for chain-terminating DNA sequencing should possess the following features: (1) incorporate dideoxy- and other modified nucleotides at an efficiency similar to that of the cognate deoxynucleotides; (2) high processivity; (3) high fidelity in the absence of proofreading/exonuclease activity; and...

journal_title：Frontiers in microbiology

authors： Zhu B

更新日期：2014-04-16 00:00:00

abstract：:The oral cavity is a complex environment harboring diverse microbial species that often co-exist within biofilms formed on oral surfaces. Within a biofilm, inter-species interactions can be synergistic in that the presence of one organism generates a niche for another enhancing colonization. Among these species are th...

journal_title：Frontiers in microbiology

authors： Khoury ZH,Vila T,Puthran TR,Sultan AS,Montelongo-Jauregui D,Melo MAS,Jabra-Rizk MA

更新日期：2020-02-28 00:00:00

abstract：:Marine Bacteroidetes constitute a very abundant bacterioplankton group in the oceans that plays a key role in recycling particulate organic matter and includes several photoheterotrophic members containing proteorhodopsin. Relatively few marine Bacteroidetes species have been described and, moreover, they correspond t...

journal_title：Frontiers in microbiology

authors： Royo-Llonch M,Ferrera I,Cornejo-Castillo FM,Sánchez P,Salazar G,Stepanauskas R,González JM,Sieracki ME,Speich S,Stemmann L,Pedrós-Alió C,Acinas SG

更新日期：2017-07-25 00:00:00

abstract：:Three chemical epigenetic modifiers [5-azacytidine, nicotinamide, and suberoylanilide hydroxamic acid (SAHA)] were applied to induce the metabolites of Penicillium mallochii CCH01, a fungus isolated from the gut of Ectropis oblique. Metabolite profiles of P. mallochii CCH01 were obviously changed by SAHA treatment. Fo...

journal_title：Frontiers in microbiology

authors： Zhang S,Fang H,Yin C,Wei C,Hu J,Zhang Y

更新日期：2019-10-02 00:00:00

abstract：:Major foodborne bacterial pathogens, such as Campylobacter jejuni, have devised complex strategies to establish and foster intestinal infections. For more than two decades, researchers have used immortalized cell lines derived from human intestinal tissue to dissect C. jejuni-host cell interactions. Known from these s...

journal_title：Frontiers in microbiology

authors： Negretti NM,Clair G,Talukdar PK,Gourley CR,Huynh S,Adkins JN,Parker CT,Corneau CM,Konkel ME

更新日期：2019-04-11 00:00:00

abstract：:Avian paramyxovirus serotype 3 (APMV-3) causes infection in a wide variety of avian species, but it does not cause apparent diseases in chickens. On the contrary, APMV-1, also known as Newcastle disease virus (NDV), can cause severe disease in chickens. Currently, natural low virulence strains of NDV are used as live-...

journal_title：Frontiers in microbiology

authors： Yoshida A,Samal SK

更新日期：2017-04-20 00:00:00

abstract：:Plants shape distinct, species-specific microbiomes in their rhizospheres. A main premise for evaluating microbial communities associated with root-soil compartments is their successful separation into the rhizosphere (soil-root interface), the rhizoplane (root surface), and the endosphere (inside roots). We evaluated...

journal_title：Frontiers in microbiology

authors： Richter-Heitmann T,Eickhorst T,Knauth S,Friedrich MW,Schmidt H

更新日期：2016-05-24 00:00:00

abstract：:Oncolytic viruses (OVs) induce antitumor effect by both direct lysis of target cells and eliciting immunogenic response to the virus and ultimately to the target cells. These viruses are usually natural human pathogens. Bacteriophages are natural pathogens of bacteria that do not infect human and have greater advantag...

journal_title：Frontiers in microbiology

authors： Hwang YJ,Myung H

更新日期：2020-09-24 00:00:00

abstract：:Microorganisms perform countless tasks on Earth and they are expected to be essential for human space exploration. Despite the interest in the responses of bacteria to space conditions, the findings on the effects of microgravity have been contradictory, while the effects of Martian gravity are nearly unknown. We perf...

journal_title：Frontiers in microbiology

authors： Santomartino R,Waajen AC,de Wit W,Nicholson N,Parmitano L,Loudon CM,Moeller R,Rettberg P,Fuchs FM,Van Houdt R,Finster K,Coninx I,Krause J,Koehler A,Caplin N,Zuijderduijn L,Zolesi V,Balsamo M,Mariani A,Pellari SS,C

更新日期：2020-10-14 00:00:00

abstract：:Intestinal microecology has been shown to participate in the pathogenesis of many diseases through different pathways, and the intestinal microecology of premature infants is significantly different from full-term infants. Intestinal microecology in premature infants is affected by various factors such as gestational ...

journal_title：Frontiers in microbiology

authors： Chen C,Yin Q,Wu H,Cheng L,Kwon JI,Jin J,Han T,Che H

更新日期：2020-01-17 00:00:00

abstract：:Both intrinsic and extrinsic mechanisms regulating bacterial expression have been elucidated and described, however, such studies have mainly focused on local effects on the two-dimensional structure of the prokaryote genome while long-range as well as spatial interactions influencing gene expression are still only po...

journal_title：Frontiers in microbiology

authors： Krogh TJ,Franke A,Møller-Jensen J,Kaleta C

更新日期：2020-09-01 00:00:00

abstract：:H7N9 influenza virus was first isolated in 2013 and has caused five epidemic waves among humans to date. Treatment opinions are currently limited. Previously, we characterized a human neutralizing antibody, HNIgGA6, by isolating rearranged heavy- and light-chain genes from convalescent patients. The mAb disrupts viral...

journal_title：Frontiers in microbiology

authors： Chen C,Liu Z,Liu L,Wang J,Jin Q

更新日期：2020-06-19 00:00:00

abstract：:Antibiotic treatment of sick dairy cattle is critical for the sustainability of this production system which is vital for food security and societal prosperity in many low and middle-income countries. Given the increasingly high levels of antibiotic resistance worldwide and the challenge this presents for the treatmen...

journal_title：Frontiers in microbiology

authors： Mainda G,Lupolova N,Sikakwa L,Richardson E,Bessell PR,Malama SK,Kwenda G,Stevens MP,Bronsvoort BMD,Muma JB,Gally DL

更新日期：2019-05-31 00:00:00

abstract：:Lactic acid bacteria (LAB) are the primary genera of the intestinal flora and have many probiotic functions. In the present study, Lactobacillus rhamnosus GG (LGG) ATCC 53103 was used to treat BALB/c mice. After LGG intervention, both low and high LGG doses were shown to improve the observed OTU, Chao1, ACE, and Shann...

journal_title：Frontiers in microbiology

authors： Shi CW,Cheng MY,Yang X,Lu YY,Yin HD,Zeng Y,Wang RY,Jiang YL,Yang WT,Wang JZ,Zhao DD,Huang HB,Ye LP,Cao X,Yang GL,Wang CF

更新日期：2020-12-17 00:00:00