Enhanced Potency of a Broad H7N9-Neutralizing Antibody HNIgGA6 Through Structure-Based Design.

abstract：:Enterotoxigenic Escherichia coli (ETEC) are opportunistic pathogens that colonize the small intestine, produce enterotoxins and induce diarrhea. Some aquaporins (AQPs), such as AQP3 and AQP8, have been reported to participate in diarrhea by decreasing cellular influx in the gastrointestinal (GI) tract. AQP4 is another...

journal_title：Frontiers in microbiology

authors： Zhang D,Yang L,Su W,Zhao Y,Ma X,Zhou H,Xu B,Zhang K,Ma H

更新日期：2018-01-09 00:00:00

abstract：:Biological nitrogen fixation plays a crucial role in the nitrogen cycle. An ability to fix atmospheric nitrogen, reducing it to ammonium, was described for multiple species of Bacteria and Archaea. The transcriptional regulatory network for nitrogen fixation was extensively studied in several representatives of the cl...

journal_title：Frontiers in microbiology

authors： Tsoy OV,Ravcheev DA,Čuklina J,Gelfand MS

更新日期：2016-08-26 00:00:00

abstract：:Lactic acid bacteria (LAB) are important for human health. However, the relative abundance of LAB in complex samples, such as fecal samples, is low and their presence and diversity (at the species level) is understudied. Therefore, we designed LAB-specific primer pairs based on 16S rRNA gene consensus sequences from 4...

journal_title：Frontiers in microbiology

authors： Hou Q,Bai X,Li W,Gao X,Zhang F,Sun Z,Zhang H

更新日期：2018-08-31 00:00:00

abstract：:Extracellular DNA is found in all environments and is a dynamic component of the microbial ecosystem. Microbial cells produce and interact with extracellular DNA through many endogenous mechanisms. Extracellular DNA is processed and internalized for use as genetic information and as a major source of macronutrients, a...

journal_title：Frontiers in microbiology

authors： Chimileski S,Dolas K,Naor A,Gophna U,Papke RT

更新日期：2014-02-20 00:00:00

abstract：:Aeolian prokaryotic communities (APC) are important components of bioaerosols that are transported freely or attached to dust particles suspended in the atmosphere. Terrestrial and marine ecosystems are known to release and receive significant prokaryote loads into and from the surrounded atmospheric air. However, com...

journal_title：Frontiers in microbiology

authors： Aalismail NA,Díaz-Rúa R,Ngugi DK,Cusack M,Duarte CM

更新日期：2020-11-12 00:00:00

abstract：:Mycobacteria are able to form dormant cells, which survive for a long time without multiplication. The molecular mechanisms behind prolonged survival of dormant cells are not fully described. In particular, little information is known on biochemical processes which might take place in cells under dormancy. To gain ins...

journal_title：Frontiers in microbiology

authors： Trutneva K,Shleeva M,Nikitushkin V,Demina G,Kaprelyants A

更新日期：2018-09-04 00:00:00

abstract：:Currently microorganisms are best identified using 16S rRNA and 18S rRNA gene sequencing. However, in recent years matrix assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) has emerged as a potential tool for microbial identification and diagnosis. During the MALDI-TOF MS process, mic...

journal_title：Frontiers in microbiology

authors： Singhal N,Kumar M,Kanaujia PK,Virdi JS

更新日期：2015-08-05 00:00:00

abstract：:Toxoplasmosis, which is one of the most widespread zoonoses worldwide, has a high incidence and infection can result in severe disease in humans and livestock. Citrate synthase (CS) is a component of nearly all living cells that plays a vital role in the citric acid cycle, which is the central metabolic pathway of aer...

journal_title：Frontiers in microbiology

authors： Liu X,Ma Q,Sun X,Lu M,Ehsan M,Hasan MW,Xu L,Yan R,Song X,Li X

更新日期：2017-07-21 00:00:00

abstract：:Clostridium difficile is a common cause of health-care acquired diarrhea, resulting in a spectrum of disease from mild diarrhea to life-threatening illness. Sixty Lactobacillus strains were screened for anti-C. difficile activity using a co-culture method. Based on their ability to inhibit C. difficile, L. gasseri APC...

journal_title：Frontiers in microbiology

authors： Quigley L,Coakley M,Alemayehu D,Rea MC,Casey PG,O'Sullivan Ó,Murphy E,Kiely B,Cotter PD,Hill C,Ross RP

更新日期：2019-02-20 00:00:00

abstract：:Due to Earth's changing climate, the ongoing and foreseeable spreading of mycotoxigenic Aspergillus species has increased the possibility of mycotoxin contamination in the feed and food production chain. These harmful mycotoxins have aroused serious health and economic problems since their first appearance. The most p...

journal_title：Frontiers in microbiology

authors： Ráduly Z,Szabó L,Madar A,Pócsi I,Csernoch L

更新日期：2020-01-09 00:00:00

abstract：:Foodborne diseases (FBDs) are infections of the gastrointestinal tract caused by foodborne pathogens (FBPs) such as bacteria [Salmonella, Listeria monocytogenes and Shiga toxin-producing E. coli (STEC)] and several viruses, but also parasites and some fungi. Artificial intelligence (AI) and its sub-discipline machine ...

journal_title：Frontiers in microbiology

authors： Vilne B,Meistere I,Grantiņa-Ieviņa L,Ķibilds J

更新日期：2019-08-06 00:00:00

abstract：:Phosphorus (P) is an essential nutrient element for the growth of phytoplankton. How P deficiency affects population growth and the cell division cycle in dinoflagellates has only been studied in some species, and how it affects photosynthesis and cell growth remains poorly understood. In the present study, we investi...

journal_title：Frontiers in microbiology

authors： Li M,Shi X,Guo C,Lin S

更新日期：2016-06-01 00:00:00

abstract：AIM:To compare the immediate antibacterial effect of two application methods (passive immersion and active mouthwash) of two antiseptic solutions on the in situ oral biofilm. MATERIAL AND METHODS:A randomized observer-masked crossover study was conducted. Fifteen healthy volunteers wore a specific intraoral device for...

journal_title：Frontiers in microbiology

authors： Prada-López I,Quintas V,Casares-De-Cal MA,Suárez-Quintanilla JA,Suárez-Quintanilla D,Tomás I

更新日期：2015-07-02 00:00:00

abstract：:In this study, we characterized the β-lactamase genes and phenotypic resistance of cephalosporin-resistant Enterobacteriaceae isolated from retail foods in China. Of 1,024 Enterobacteriaceae isolates recovered from raw meat products, aquatic products, raw vegetables, retail-level ready-to-eat (RTE) foods, frozen foods...

journal_title：Frontiers in microbiology

authors： Ye Q,Wu Q,Zhang S,Zhang J,Yang G,Wang J,Xue L,Chen M

更新日期：2018-08-08 00:00:00

abstract：:Peptide Nucleic Acid (PNA)-peptide conjugates targeting essential bacterial genes are showing promise as antisense antimicrobials in drug discovery. Optimization has focused on selection of target genes and exact localization around the ribosome binding site, but surprisingly a length optimum around 10-12 nucleobases ...

journal_title：Frontiers in microbiology

authors： Goltermann L,Yavari N,Zhang M,Ghosal A,Nielsen PE

更新日期：2019-05-24 00:00:00

abstract：:Proteus spp. are commensal Enterobacterales of the human digestive tract. At the same time, P. mirabilis is commonly involved in urinary tract infections (UTI). P. mirabilis is naturally resistant to several antibiotics including colistin and shows reduced susceptibility to imipenem. However higher levels of resistanc...

journal_title：Frontiers in microbiology

authors： Girlich D,Bonnin RA,Dortet L,Naas T

更新日期：2020-02-21 00:00:00

abstract：:As the highest place of the world, the Tibetan plateau is a fragile ecosystem. Given the importance of microbial communities in driving soil nutrient cycling, it is of interest to document the microbial biogeographic pattern here. We adopted a microarray-based tool named GeoChip 4.0 to investigate grassland microbial ...

journal_title：Frontiers in microbiology

authors： Qi Q,Zhao M,Wang S,Ma X,Wang Y,Gao Y,Lin Q,Li X,Gu B,Li G,Zhou J,Yang Y

更新日期：2017-06-13 00:00:00

abstract：:Lycium barbarum is a boxthorn that produces the goji berries. The aim of the current study was to evaluate the proliferative effect of L. barbarum polysaccharides (LBP) on probiotics. LBP was extracted from goji berries and its monosaccharide composition characterized by gas chromatography (GC). The LBP extract contai...

journal_title：Frontiers in microbiology

authors： Zhou F,Jiang X,Wang T,Zhang B,Zhao H

更新日期：2018-05-18 00:00:00

abstract：:Oncolytic viruses (OVs) induce antitumor effect by both direct lysis of target cells and eliciting immunogenic response to the virus and ultimately to the target cells. These viruses are usually natural human pathogens. Bacteriophages are natural pathogens of bacteria that do not infect human and have greater advantag...

journal_title：Frontiers in microbiology

authors： Hwang YJ,Myung H

更新日期：2020-09-24 00:00:00

abstract：:Recombinant subunit vaccines are some of the safest and most effective vaccines available, but their high cost and the requirement of advanced medical infrastructure for administration make them impractical for many developing world diseases. Plant-based vaccines have shifted that paradigm by paving the way for recomb...

journal_title：Frontiers in microbiology

authors： Specht EA,Mayfield SP

更新日期：2014-02-17 00:00:00

abstract：:The mitochondrial genome of the Paracoccidioides brasiliensis reference isolate Pb18 was first sequenced and described by Cardoso et al. (2007), as a circular genome with a size of 71.3 kb and containing 14 protein coding genes, 25 tRNAs, and the large and small subunits of ribosomal RNA. Later in 2011, Desjardins et ...

journal_title：Frontiers in microbiology

authors： Misas E,Gómez OM,Botero V,Muñoz JF,Teixeira MM,Gallo JE,Clay OK,McEwen JG

更新日期：2020-08-04 00:00:00

abstract：:Antimycotic chemosensitization and its mode of action are of growing interest. Currently, use of antifungal agents in agriculture and medicine has a number of obstacles. Foremost of these is development of resistance or cross-resistance to one or more antifungal agents. The generally high expense and negative impact, ...

journal_title：Frontiers in microbiology

authors： Campbell BC,Chan KL,Kim JH

更新日期：2012-02-29 00:00:00

abstract：:Colonies are an abundant form of bacterial multicellularity; however, relatively little is known about the initial stages of their construction. We have previously described that colony development of the soil bacterium Bacillus subtilis is a highly ordered process, typically initiating with the formation of extending...

journal_title：Frontiers in microbiology

authors： Mamou G,Fiyaksel O,Sinai L,Ben-Yehuda S

更新日期：2017-10-24 00:00:00

abstract：:Estuarine sediments are significant repositories of anthropogenic contaminants, and thus knowledge of the impacts of pollution upon microbial communities in these environments is important to understand potential effects on estuaries as a whole. The Lagos lagoon (Nigeria) is one of Africa's largest estuarine ecosystem...

journal_title：Frontiers in microbiology

authors： Obi CC,Adebusoye SA,Ugoji EO,Ilori MO,Amund OO,Hickey WJ

更新日期：2016-08-05 00:00:00

abstract：Background:Wallemia ichthyophaga is a highly specialized basidiomycetous fungus. It is one of the most halophilic fungi ever described, only able to grow at low water activity. This specialization is thought to explain why it is only rarely isolated from nature. Results:Genomes of 21 W. ichthyophaga strains were seque...

journal_title：Frontiers in microbiology

authors： Gostinčar C,Sun X,Zajc J,Fang C,Hou Y,Luo Y,Gunde-Cimerman N,Song Z

更新日期：2019-09-04 00:00:00

abstract：:Biofilms are surface-attached communities of bacterial cells embedded in a self-produced matrix that are found ubiquitously in nature. The biofilm matrix is composed of various extracellular polymeric substances, which confer advantages to the encapsulated bacteria by protecting them from eradication. The matrix compo...

journal_title：Frontiers in microbiology

authors： Whitfield GB,Marmont LS,Howell PL

更新日期：2015-05-15 00:00:00

abstract：:Fifteen years after transfer to hops, hop stunt viroid-grapevine (HSVd-g) was replaced by HSVd-hop (HSVd-h), a sequence variant that contains changes at five different positions. HSVd-g54 is a laboratory mutant derived from HSVd-g that differs from its progenitor by a single G to A substitution at position 54. While i...

journal_title：Frontiers in microbiology

authors： Xia C,Li S,Hou W,Fan Z,Xiao H,Lu M,Sano T,Zhang Z

更新日期：2017-12-12 00:00:00

abstract：:Escherichia coli O104:H4, a Shiga toxin-producing hybrid pathotype that was implicated in a major foodborne outbreak in Germany in 2011, has not been detected in cattle. However, serotypes of O104, other than O104:H4, have been isolated from cattle feces, with O104:H7 being the most predominant. In this study, we inve...

journal_title：Frontiers in microbiology

authors： Shridhar PB,Patel IR,Gangiredla J,Noll LW,Shi X,Bai J,Elkins CA,Strockbine NA,Nagaraja TG

更新日期：2018-03-01 00:00:00

abstract：:The Chlamydiaceae comprise a group of highly adapted bacterial pathogens sharing a unique intracellular lifestyle. Three Chlamydia species are pathogenic to humans: Chlamydia trachomatis, Chlamydia pneumoniae, and Chlamydia psittaci. C. trachomatis is the leading bacterial cause of sexually-transmitted infections and ...

journal_title：Frontiers in microbiology

authors： Panzetta ME,Valdivia RH,Saka HA

更新日期：2018-12-12 00:00:00

abstract：:Paracoccidioidomycosis (PCM) is an endemic mycosis in Latin American caused by the thermodimorphic fungi of the genus Paracoccidioides spp. Notably, a Th1 immune response is required to control PCM. In this context, dendritic cells (DCs) seem to be essential players in capture, processing and presentation of Paracocci...

journal_title：Frontiers in microbiology

authors： Silva LBR,Taira CL,Dias LS,Souza ACO,Nosanchuk JD,Travassos LR,Taborda CP

更新日期：2019-07-31 00:00:00