Elucidating the Influence of Chromosomal Architecture on Transcriptional Regulation in Prokaryotes - Observing Strong Local Effects of Nucleoid Structure on Gene Regulation.

abstract：Rationale:Although frequently retrieved in tracheal secretions of critically ill patients on mechanical ventilation, the existence of pneumonia caused by coagulase-negative staphylococci (CoNS) remains controversial. Objective:To assess whether Staphylococcus haemolyticus (S. haemolyticus) inoculated in mice's trachea...

journal_title：Frontiers in microbiology

authors： Shi MM,Monsel A,Rouby JJ,Xu YP,Zhu YG,Qu JM

更新日期：2019-10-04 00:00:00

abstract：:Human rhinovirus (HRV) remains a leading cause of several human diseases including the common cold. Despite considerable research over the last 60 years, development of an effective vaccine to HRV has been viewed by many as unfeasible due, in part, to the antigenic diversity of circulating HRVs in nature. Over 150 ant...

journal_title：Frontiers in microbiology

authors： Stobart CC,Nosek JM,Moore ML

更新日期：2017-12-05 00:00:00

abstract：:Metabolic syndrome (MetS) is the underlying cause of some devastating diseases, including type 2 diabetes and cardiovascular disease. These diseases have been associated with over-activation of the mechanistic Target of Rapamycin (mTOR) pathway. This study utilizes a high fat diet (HFD) to induce MetS and to dissect t...

journal_title：Frontiers in microbiology

authors： Kling DN,DeBose-Scarlett EM,Teixeira LD,Gezan SA,Lorca GL,Gonzalez CF

更新日期：2018-11-06 00:00:00

abstract：:Chili (Capsicum annuum L.) is an important vegetable and spice crop of tropical and sub-tropical regions. Chili plants showing upward leaf curling, leaf crinkling, and leaf yellowing symptoms, collected from Sikar district of Rajasthan, India, were found to be associated with begomovirus and satellite molecules. The p...

journal_title：Frontiers in microbiology

authors： Mishra M,Verma RK,Marwal A,Sharma P,Gaur RK

更新日期：2020-10-07 00:00:00

abstract：:Pseudomonas aeruginosa (PA) is the leading cause of corneal blindness worldwide. A constant increase in multi-drug resistant PA strains have heightened the challenge of effectively managing corneal infections with conventional antibiotics. Antimicrobial peptides are promising antibiotic analogs with a unique mode of a...

journal_title：Frontiers in microbiology

authors： Mohammed I,Said DG,Nubile M,Mastropasqua L,Dua HS

更新日期：2019-09-19 00:00:00

abstract：:Pseudomonas aeruginosa is an opportunistic pathogen commonly infecting immunocompromised patients with diseases like cystic fibrosis (CF) and cancers and has high rates of recurrence and mortality. The treatment efficacy can be significantly worsened by the multidrug resistance (MDR) of P. aeruginosa, and there is inc...

journal_title：Frontiers in microbiology

authors： Guo DD,Luo LM,Ma HL,Zhang SP,Xu H,Zhang H,Wang Y,Yuan Y,Wang Z,He YX

更新日期：2020-07-08 00:00:00

abstract：:IgaA is an integral inner membrane protein that was discovered as repressor of the RcsCDB phosphorelay system in the intracellular pathogen Salmonella enterica serovar Typhimurium. The RcsCDB system, conserved in many members of the family Enterobacteriaceae, regulates expression of varied processes including motility...

journal_title：Frontiers in microbiology

authors： Pucciarelli MG,Rodríguez L,García-Del Portillo F

更新日期：2017-12-22 00:00:00

abstract：:Carbapenem-resistant Acinetobacter baumannii (CRAB) are emerging worldwide. In South America, clinical isolates presenting such a phenotype usually do not belong to the globally distributed international clone 2 (IC2). The majority of these isolates are also resistant to multiple other antimicrobials and are often des...

journal_title：Frontiers in microbiology

authors： Nodari CS,Cayô R,Streling AP,Lei F,Wille J,Almeida MS,de Paula AI,Pignatari ACC,Seifert H,Higgins PG,Gales AC

更新日期：2020-11-30 00:00:00

abstract：:The High Arctic is dominated by polar desert habitats whose microbial communities are poorly understood. In this study, we used next generation sequencing to describe the α- and β-diversity of microbial communities in polar desert soils from the Kongsfjorden region of Svalbard. Ten phyla dominated the soils and accoun...

journal_title：Frontiers in microbiology

authors： McCann CM,Wade MJ,Gray ND,Roberts JA,Hubert CR,Graham DW

更新日期：2016-03-31 00:00:00

abstract：:In this article we compare the efficacy of different pharmacological agents (ranitidine, and omeprazole) to support phage transit from stomach to distal portions of the gastrointestinal tract in rats. We show that a temporal modification of environment in the animal stomach may protect Twort-like therapeutic antistaph...

journal_title：Frontiers in microbiology

authors： Międzybrodzki R,Kłak M,Jończyk-Matysiak E,Bubak B,Wójcik A,Kaszowska M,Weber-Dąbrowska B,Łobocka M,Górski A

更新日期：2017-03-23 00:00:00

abstract：:Soil dwelling Streptomyces species are faced with large variations in carbon or nitrogen sources, phosphate, oxygen, iron, sulfur, and other nutrients. These drastic changes in key nutrients result in an unbalanced metabolism that have undesirable consequences for growth, cell differentiation, reproduction, and second...

journal_title：Frontiers in microbiology

authors： Martín JF,Liras P

更新日期：2020-01-22 00:00:00

abstract：:Microbial communities in the endosphere of Salicaceae plants, poplar (Populus trichocarpa) and willow (Salix sitchensis), have been demonstrated to be important for plant growth promotion, protection from biotic and abiotic stresses, and degradation of toxic compounds. Our study aimed to investigate bio-control activi...

journal_title：Frontiers in microbiology

authors： Kandel SL,Firrincieli A,Joubert PM,Okubara PA,Leston ND,McGeorge KM,Mugnozza GS,Harfouche A,Kim SH,Doty SL

更新日期：2017-03-13 00:00:00

abstract：:Mobile genetic elements, including plasmids, drive the evolution of prokaryotic genomes through the horizontal transfer of genes allowing genetic exchange between bacteria. Moreover, plasmids carry accessory genes, which encode functions that may offer an advantage to the host. Thus, it is expected that in a certain e...

journal_title：Frontiers in microbiology

authors： Perez MF,Kurth D,Farías ME,Soria MN,Castillo Villamizar GA,Poehlein A,Daniel R,Dib JR

更新日期：2020-06-23 00:00:00

abstract：:Microorganisms perform countless tasks on Earth and they are expected to be essential for human space exploration. Despite the interest in the responses of bacteria to space conditions, the findings on the effects of microgravity have been contradictory, while the effects of Martian gravity are nearly unknown. We perf...

journal_title：Frontiers in microbiology

authors： Santomartino R,Waajen AC,de Wit W,Nicholson N,Parmitano L,Loudon CM,Moeller R,Rettberg P,Fuchs FM,Van Houdt R,Finster K,Coninx I,Krause J,Koehler A,Caplin N,Zuijderduijn L,Zolesi V,Balsamo M,Mariani A,Pellari SS,C

更新日期：2020-10-14 00:00:00

abstract：:Campylobacter jejuni is the major cause of human bacterial diarrhea worldwide. Its pathogenic mechanism remains poorly understood. cj0371 is a novel gene that was uncovered using immunoscreening. There have been no previous reports regarding its function. In this study, we constructed an insertion mutant and complemen...

journal_title：Frontiers in microbiology

authors： Du X,Wang N,Ren F,Tang H,Jiao X,Huang J

更新日期：2016-07-14 00:00:00

abstract：:The study of inorganic nutrients dynamics in shallow sediments usually focuses on two main pools: porewater (PW) nutrients and exchangeable (EX) ammonium and phosphate. Recently, it has been found that microphytobenthos (MPB) and other microorganisms can accumulate large amounts of nutrients intracellularly (IC), high...

journal_title：Frontiers in microbiology

authors： Garcia-Robledo E,Bohorquez J,Corzo A,Jimenez-Arias JL,Papaspyrou S

更新日期：2016-05-26 00:00:00

abstract：:Cold-adapted fungi isolated from Antarctica, in particular those belonging to the genus Pseudogymnoascus, are producers of secondary metabolites with interesting bioactive properties as well as enzymes with potential biotechnological applications. However, at genetic level, the study of these fungi has been hindered b...

journal_title：Frontiers in microbiology

authors： Díaz A,Villanueva P,Oliva V,Gil-Durán C,Fierro F,Chávez R,Vaca I

更新日期：2019-11-22 00:00:00

abstract：:Chitosan is a natural biopolymer from crab shells that is known for its biocompatibility, biodegradability, and bioactivity. In human medicine, chitosan is used as a stabilizer for active ingredients in tablets, and is popular in slimming diets. Due to its low toxicity, it was the first basic substance approved by the...

journal_title：Frontiers in microbiology

authors： Romanazzi G,Feliziani E,Sivakumar D

更新日期：2018-12-04 00:00:00

abstract：:A Viable but non-culturable (VBNC) state is a bacterial survival strategy under reverse conditions. It poses a significant challenge for public health and food safety. In this study, the effect of external environmental conditions including acid, nutrition, and salt concentrations on the formation of S. aureus VBNC st...

journal_title：Frontiers in microbiology

authors： Li Y,Huang TY,Mao Y,Chen Y,Shi F,Peng R,Chen J,Yuan L,Bai C,Chen L,Wang K,Liu J

更新日期：2020-11-26 00:00:00

abstract：:Parvoviruses are a diverse group of viruses that are capable of infecting a wide range of animals. In this study, we report the discovery of a novel parvovirus, tilapia parvovirus HMU-HKU, in the fecal samples of crocodiles and intestines of tilapia in Hainan Province, China. The novel parvovirus was firstly identifie...

journal_title：Frontiers in microbiology

authors： Du J,Wang W,Chan JF,Wang G,Huang Y,Yi Y,Zhu Z,Peng R,Hu X,Wu Y,Zeng J,Zheng J,Cui X,Niu L,Zhao W,Lu G,Yuen KY,Yin F

更新日期：2019-12-05 00:00:00

abstract：:The ocean is considered to be a great reservoir of biodiversity. Microbial communities in marine environments are ecologically relevant as intermediaries of energy, and play an important role in nutrient regeneration cycles as decomposers of dead and decaying organic matter. In this sense, marine-derived fungi can be ...

journal_title：Frontiers in microbiology

authors： Bonugli-Santos RC,Dos Santos Vasconcelos MR,Passarini MR,Vieira GA,Lopes VC,Mainardi PH,Dos Santos JA,de Azevedo Duarte L,Otero IV,da Silva Yoshida AM,Feitosa VA,Pessoa A Jr,Sette LD

更新日期：2015-04-10 00:00:00

abstract：:Clostridium difficile infection (CDI) is a major cause of infectious diarrhea among hospitalized patients. Probiotics could be instrumental in restoring the intestinal dysbiosis caused by CDI. Here, we examined the protective effect of Pediococcus pentosaceus LI05 in a mouse CDI model. C57BL/6 mice were administrated ...

journal_title：Frontiers in microbiology

authors： Xu Q,Gu S,Chen Y,Quan J,Lv L,Chen D,Zheng B,Xu L,Li L

更新日期：2018-10-09 00:00:00

abstract：:We present the details of a numerical model, BIOB that is capable of simulating the biodegradation of oil entrapped in the sediment. The model uses Monod kinetics to simulate the growth of bacteria in the presence of nutrients and the subsequent consumption of hydrocarbons. The model was used to simulate experimental ...

journal_title：Frontiers in microbiology

authors： Torlapati J,Boufadel MC

更新日期：2014-05-14 00:00:00

abstract：:Kaposi's sarcoma-associated herpesvirus (KSHV), also called human herpesvirus 8, belongs to the gamma herpesviruses and is the etiological agent of Kaposi's sarcoma, primary effusion lymphoma, and some types of multicentric Castleman's disease. In vivo, KSHV mainly infects B cells and endothelial cells. The interactio...

journal_title：Frontiers in microbiology

authors： Liang D,Lin X,Lan K

更新日期：2012-01-11 00:00:00

abstract：:Soil microorganisms historically have been a rich resource for natural product discovery, yet the majority of these microbes remain uncultivated and their biosynthetic capacity is left underexplored. To identify the biosynthetic potential of soil microorganisms using a culture-independent approach, we constructed a la...

journal_title：Frontiers in microbiology

authors： Santana-Pereira ALR,Sandoval-Powers M,Monsma S,Zhou J,Santos SR,Mead DA,Liles MR

更新日期：2020-12-07 00:00:00

abstract：:Babesia species are tick-borne intraerythrocytic protozoa that cause babesiosis in humans worldwide. No vaccine has yet proven effective against Babesia infection. Surface antigens of merozoites are involved in the invasion of erythrocytes by Babesia. Surface antigens may be presented by both babesial sporozoites and ...

journal_title：Frontiers in microbiology

authors： Man S,Fu Y,Guan Y,Feng M,Qiao K,Li X,Gao H,Cheng X

更新日期：2017-12-19 00:00:00

abstract：:Coinfection by bovine respiratory syncytial virus (BRSV) and Pasteurella multocida (PM) frequently has been observed in cattle that develop severe pneumonia. We recently reported that BRSV infection significantly increased PM adherence to bovine lower respiratory tract epithelial cells. However, the molecular mechanis...

journal_title：Frontiers in microbiology

authors： Sudaryatma PE,Saito A,Mekata H,Kubo M,Fahkrajang W,Mazimpaka E,Okabayashi T

更新日期：2020-07-31 00:00:00

abstract：:Haemophilus parasuis is known as a commensal organism discovered in the upper respiratory tract of swine where the pathogenic bacteria survive in various adverse environmental stress. QseC, a histidine protein kinase of the two-component regulatory systems CheY/QseC, is involved in the environmental adaptation in bact...

journal_title：Frontiers in microbiology

authors： He L,Dai K,Wen X,Ding L,Cao S,Huang X,Wu R,Zhao Q,Huang Y,Yan Q,Ma X,Han X,Wen Y

更新日期：2018-02-13 00:00:00

abstract：:Globally, mosquitoes are known to be competent vectors to various arboviruses that cause serious and debilitating diseases to humans and animals. Conversely, mosquitoes harbor a wide array of insect specific viruses (ISVs) that are generally neglected. Extensive characterization of these ISVs is important in understan...

journal_title：Frontiers in microbiology

authors： Zhao L,Mwaliko C,Atoni E,Wang Y,Zhang Y,Zhan J,Hu X,Xia H,Yuan Z

更新日期：2019-08-22 00:00:00

abstract：:Through the expression of the accessory gene regulator quorum sensing cascade, Staphylococcus aureus is able to produce an extensive array of enzymes, hemolysins and immunomodulators essential to its ability to spread through the host tissues and cause disease. Many have argued for the discovery and development of quo...

journal_title：Frontiers in microbiology

authors： Quave CL,Horswill AR

更新日期：2014-12-12 00:00:00