Back to the future: forget ultrasound and focus on clinical assessment in rheumatoid arthritis management.

abstract：OBJECTIVES:To assess the prevalence and patterns of cardiac abnormalities as detected by cardiac magnetic resonance imaging (MRI) in systemic sclerosis (SSc). METHODS:Fifty-two consecutive patients with SSc underwent cardiac MRI to determine morphological, functional, perfusion at rest and delayed enhancement abnormal...

journal_title：Annals of the rheumatic diseases

authors： Hachulla AL,Launay D,Gaxotte V,de Groote P,Lamblin N,Devos P,Hatron PY,Beregi JP,Hachulla E

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVE:To identify potential risk factors for the onset of inflammatory arthritis (IA) in a large cohort of patients with psoriatic arthritis (PsA) of recent onset. METHODS:We recruited cases with psoriasis and an onset of IA within the past 5 years. Controls were patients who had psoriasis but no arthritis. We ass...

journal_title：Annals of the rheumatic diseases

authors： Pattison E,Harrison BJ,Griffiths CE,Silman AJ,Bruce IN

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVE:To compare ultrasound measurement of median nerve cross-sectional area (CSA) at different anatomical landmarks and to assess the value of power Doppler signals within the median nerve for diagnosis of carpal tunnel syndrome (CTS). METHODS:A prospective study of 135 consecutive patients with suspected CTS und...

journal_title：Annals of the rheumatic diseases

authors： Dejaco C,Stradner M,Zauner D,Seel W,Simmet NE,Klammer A,Heitzer P,Brickmann K,Gretler J,Fürst-Moazedi FC,Thonhofer R,Husic R,Hermann J,Graninger WB,Quasthoff S

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:To determine whether the heterogeneous clinical response to tumour necrosis factor (TNF)alpha blocking therapy in rheumatoid arthritis (RA) can be predicted by TNFalpha expression in the synovium before initiation of treatment. METHODS:Prior to initiation of infliximab treatment, arthroscopic synovial tissue...

journal_title：Annals of the rheumatic diseases

authors： Wijbrandts CA,Dijkgraaf MG,Kraan MC,Vinkenoog M,Smeets TJ,Dinant H,Vos K,Lems WF,Wolbink GJ,Sijpkens D,Dijkmans BA,Tak PP

更新日期：2008-08-01 00:00:00

abstract：:The immune response against two herpesviruses has been determined in sera and matched synovial fluids of patients with rheumatoid arthritis (RA) and compared with that of a healthy control population. The increased level of antibody to Epstein-Barr virus (EBV) induced antigens in patients with RA resembles the antibod...

journal_title：Annals of the rheumatic diseases

authors： Musiani M,Zerbini M,Ferri S,Plazzi M,Gentilomi G,La Placa M

更新日期：1987-11-01 00:00:00

abstract：OBJECTIVE:To compare two plain radiographic methods for sensitivity to detect progression of patellofemoral osteoarthritis. METHODS:Two sets of paired skyline and lateral knee radiographs from 54 hospital referred patients (108 knees) with knee osteoarthritis were taken an average of 31 months apart (range 12-40). Fil...

journal_title：Annals of the rheumatic diseases

authors： Lanyon P,Jones A,Doherty M

更新日期：1996-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the safety, tolerability, pharmacokinetic and pharmacodynamic profiles of mavrilimumab, a human monoclonal antibody targeting the granulocyte-macrophage colony-stimulating factor receptor-α, in subjects with rheumatoid arthritis (RA). METHODS:A randomised, double-blind, placebo-controlled, dose-e...

journal_title：Annals of the rheumatic diseases

authors： Burmester GR,Feist E,Sleeman MA,Wang B,White B,Magrini F

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVE:Anticitrullinated protein antibodies (ACPA) are the most predictive factor for the development of rheumatoid arthritis (RA). Epitope spreading towards more citrullinated epitopes occurs before the onset of RA. Here, the authors investigated whether specific epitope recognition allows the identification of spe...

journal_title：Annals of the rheumatic diseases

authors： Willemze A,Böhringer S,Knevel R,Levarht EW,Stoeken-Rijsbergen G,Houwing-Duistermaat JJ,van der Helm-van Mil AH,Huizinga TW,Toes RE,Trouw LA

更新日期：2012-02-01 00:00:00

abstract：OBJECTIVES:To determine the relevance of calpain in murine collagen induced arthritis (CIA) and to correlate the presence of m-calpain with the appearance of arthritis and cartilage destruction. METHODS:The immunohistochemical appearance and localisation of m-calpain at different stages of arthritis were analysed and ...

journal_title：Annals of the rheumatic diseases

authors： Szomor Z,Shimizu K,Fujimori Y,Yamamoto S,Yamamuro T

更新日期：1995-06-01 00:00:00

abstract：OBJECTIVES:To study whether hand osteoarthritis (OA) is associated with increased mortality and cardiovascular events in a large community based cohort (Framingham Heart Study) in which OA, mortality and cardiovascular events have been carefully assessed. METHODS:We examined whether symptomatic (≥1 joint(s) with radio...

journal_title：Annals of the rheumatic diseases

authors： Haugen IK,Ramachandran VS,Misra D,Neogi T,Niu J,Yang T,Zhang Y,Felson DT

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the ability of ultrasound (US) to detect the presence and change of Achilles erosions in spondyloarthritis (SpA). METHODS:A blind prospective two-dimensional (2D) and three-dimensional (3D) US study of Achilles enthesis erosions in early SpA was undertaken. US examinations were performed at basel...

journal_title：Annals of the rheumatic diseases

authors： de Miguel E,Falcao S,Castillo C,Plasencia C,García M,Branco JC,Martín-Mola E

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVES:To develop evidence-based EULAR recommendations for cardiovascular (CV) risk management in patients with rheumatoid arthritis (RA), ankylosing spondylitis (AS) and psoriatic arthritis (PsA). METHODS:A multidisciplinary expert committee was convened as a task force of the EULAR Standing Committee for Clinica...

journal_title：Annals of the rheumatic diseases

authors： Peters MJ,Symmons DP,McCarey D,Dijkmans BA,Nicola P,Kvien TK,McInnes IB,Haentzschel H,Gonzalez-Gay MA,Provan S,Semb A,Sidiropoulos P,Kitas G,Smulders YM,Soubrier M,Szekanecz Z,Sattar N,Nurmohamed MT

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVE:To assess how socioeconomic deprivation influences the presentation, treatment, and outcome of patients with rheumatoid arthritis (RA). METHODS:Three year follow up of 869 consecutive patients with RA from nine hospital rheumatology clinics, with patients categorised by the Carstairs deprivation score of the...

journal_title：Annals of the rheumatic diseases

authors：

更新日期：2000-10-01 00:00:00

abstract：OBJECTIVES:There are no agreed criteria for osteoarthritis (OA) of the knee in population studies. The radiographic scoring system of Kellgren and Lawrence has been the system most used in the past and although other methods have been developed, comparisons have not been performed. Therefore these grading systems were ...

journal_title：Annals of the rheumatic diseases

authors： Spector TD,Hart DJ,Byrne J,Harris PA,Dacre JE,Doyle DV

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:Low sulphate levels in blood may contribute to osteoarthritis by decreasing cartilage chondroitin sulphation. OBJECTIVE:To measure serum levels of sulphate during 3 h of fasting or glucose ingestion after overnight fasts to determine how much sulphate lowering may occur during this period. METHODS:Sera fro...

journal_title：Annals of the rheumatic diseases

authors： Blinn CM,Biggee BA,McAlindon TE,Nuite M,Silbert JE

更新日期：2006-09-01 00:00:00

abstract：OBJECTIVES:Statins offer significant cardiovascular benefits. Their use, however, influences immune regulation, which may potentially facilitate autoimmunity, eventually resulting in autoimmune diseases such as rheumatoid arthritis (RA).The authors studied whether statin use was associated with an increased risk of dev...

journal_title：Annals of the rheumatic diseases

authors： de Jong HJ,Klungel OH,van Dijk L,Vandebriel RJ,Leufkens HG,van der Laan JW,Cohen Tervaert JW,van Loveren H

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:For our understanding of the pathogenesis of rheumatoid arthritis (RA), it is important to elucidate the mechanisms underlying early stages of synovitis. Here, synovial cytokine production was investigated in patients with very early arthritis. METHODS:Synovial biopsies were obtained from pat...

journal_title：Annals of the rheumatic diseases

authors： Yeo L,Adlard N,Biehl M,Juarez M,Smallie T,Snow M,Buckley CD,Raza K,Filer A,Scheel-Toellner D

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:To assess the intra and interobserver reproducibility of musculoskeletal ultrasonography (US) among rheumatologists in detecting destructive and inflammatory shoulder abnormalities in patients with rheumatoid arthritis (RA) and to determine the overall agreement between US and MRI. METHODS:A total of 14 obse...

journal_title：Annals of the rheumatic diseases

authors： Bruyn GA,Naredo E,Möller I,Moragues C,Garrido J,de Bock GH,d'Agostino MA,Filippucci E,Iagnocco A,Backhaus M,Swen WA,Balint P,Pineda C,Milutinovic S,Kane D,Kaeley G,Narvaez FJ,Wakefield RJ,Narvaez JA,de Augustin J,

更新日期：2009-03-01 00:00:00

abstract：:The possible contribution of immunological mechanisms in the development of Libman-Sacks endocarditis was studied in 2 patients with systemic lupus erythematosus who underwent aortic valve replacement. Sections of verrucous lesions, stained with haematoxylin and eosin, showed three apparently distinct zones: an outer ...

journal_title：Annals of the rheumatic diseases

authors： Shapiro RF,Gamble CN,Wiesner KB,Castles JJ,Wolf AW,Hurley EJ,Salel AF

更新日期：1977-12-01 00:00:00

abstract：OBJECTIVE:To elucidate the clinical importance of the anti-signal recognition particle (SRP) autoantibody in patients with myositis. METHODS:Retrospective systematic assessment of the clinical, laboratory and histological characteristics of 23 anti-SRP-positive patients from six European centres. Data were compared wi...

journal_title：Annals of the rheumatic diseases

authors： Hengstman GJ,ter Laak HJ,Vree Egberts WT,Lundberg IE,Moutsopoulos HM,Vencovsky J,Doria A,Mosca M,van Venrooij WJ,van Engelen BG

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Treatment with tumour necrosis factor inhibitors (TNF-i) plus methotrexate (MTX), but not MTX monotherapy alone, inhibits joint damage progression even at higher levels of disease activity. Such disassociation of disease activity and structural damage has not been shown for biological agents other than TNF-i...

journal_title：Annals of the rheumatic diseases

authors： Smolen JS,Avila JC,Aletaha D

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Preliminary clinical criteria based on age, inflammation, and immobility have been proposed to identify which patients with rheumatoid arthritis (RA) should be examined by dual energy x ray absorptiometry (DXA) to diagnose osteoporosis. The three item criteria have not been evaluated in male patients with RA...

journal_title：Annals of the rheumatic diseases

authors： Haugeberg G,Ørstavik RE,Uhlig T,Falch JA,Halse JI,Kvien TK

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVE:To describe granuloma annulare (GA) skin lesion development in patients during anti-tumour necrosis factor (TNF) therapy. METHODS:199 patients with rheumatoid arthritis and 127 suffering from spondyloarthropathies treated with anti-TNF antagonists were analysed to identify skin lesions suggesting GA. RESULT...

journal_title：Annals of the rheumatic diseases

authors： Voulgari PV,Markatseli TE,Exarchou SA,Zioga A,Drosos AA

更新日期：2008-04-01 00:00:00

abstract：:The anti-inflammatory effect of single doses and combinations of aspirin and commonly used nonsteroidal anti-inflammatory drugs was investigated by the polyurethane sponge implantation model of acute inflammation. Dose response curves were performed to delineate a suppressive (high) and nonsuppressive (low) dose of ea...

journal_title：Annals of the rheumatic diseases

authors： Garrett R,Manthey B,Vernon-Roberts B,Brooks PM

更新日期：1983-08-01 00:00:00

abstract：OBJECTIVES:With the tools available currently, confirming the diagnosis of inclusion body myositis (IBM) can be difficult. Many patients are initially misdiagnosed with polymyositis (PM). In this observational study at a UK adult neuromuscular centre, we investigated whether amyloid positron emission tomography could d...

journal_title：Annals of the rheumatic diseases

authors： Lilleker JB,Hodgson R,Roberts M,Herholz K,Howard J,Hinz R,Chinoy H

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVES:To describe the influence of the reading order (chronological v paired) on radiographic scoring results in ankylosing spondylitis. To investigate whether this method is sufficiently sensitive to change because paired reading is requested for establishing drug efficacy in clinical trials. METHODS:Films obtai...

journal_title：Annals of the rheumatic diseases

authors： Wanders A,Landewé R,Spoorenberg A,de Vlam K,Mielants H,Dougados M,van der Linden S,van der Heijde D

更新日期：2004-12-01 00:00:00

abstract：OBJECTIVES:To evaluate the risk of psoriatic arthritis (PsA) among patients with psoriasis exposed to physical trauma. METHODS:A matched cohort study was performed using data from The Health Improvement Network (THIN). Patients with psoriasis exposed to trauma were randomly matched to up to five unexposed psoriasis co...

journal_title：Annals of the rheumatic diseases

authors： Thorarensen SM,Lu N,Ogdie A,Gelfand JM,Choi HK,Love TJ

更新日期：2017-03-01 00:00:00

abstract：:In order to evaluate the incidence and aetiology of hypergastrinaemia 53 patients with seropositive rheumatoid arthritis were examined for gastric acid secretion, fasting serum gastrin concentration, circulating parietal cell antibodies, and some parameters of the activity of inflammation of rheumatoid arthritis. The ...

journal_title：Annals of the rheumatic diseases

authors： de Witte TJ,Geerdink PJ,Lamers CB,Boerbooms AM,van der Korst JK

更新日期：1979-02-01 00:00:00

abstract：:Evidence suggests that endothelin may have a fundamental role in scleroderma pathogenesis, including pulmonary arterial hypertension (PAH)--a leading cause of death in patients with scleroderma. Development of a new class of drug, endothelin receptor antagonists, heralds an improved outlook for patients with scleroder...

journal_title：Annals of the rheumatic diseases

authors： Hachulla E,Coghlan JG

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVE:To compare the clinical, radiological, and biological profile of patients presenting late onset spondylarthropathy (LOSPA) with patients with early onset spondylarthropathy (EOSPA). METHODS:During the period April 1987 to April 1995 a retrospective chart review of inpatients and outpatients identified eight ...

journal_title：Annals of the rheumatic diseases

authors： Caplanne D,Tubach F,Le Parc JM

更新日期：1997-03-01 00:00:00