Scoring of radiographic progression in randomised clinical trials in ankylosing spondylitis: a preference for paired reading order.

abstract：OBJECTIVE:To carry out a prospective two year follow up study comparing conventional radiography, three-phase bone scintigraphy, ultrasonography (US), and three dimensional (3D) magnetic resonance imaging (MRI) with precontrast and dynamic postcontrast examination in detecting early arthritis. The aim of the follow up ...

journal_title：Annals of the rheumatic diseases

authors： Backhaus M,Burmester GR,Sandrock D,Loreck D,Hess D,Scholz A,Blind S,Hamm B,Bollow M

更新日期：2002-10-01 00:00:00

abstract：:In the World Health Organisation's supplementary classification of the consequences of disease a distinction is made between impairments, such as are related to the site and nature of joint involvement, and any disabilities in everyday activities to which these may give rise. This paper considers the application of th...

journal_title：Annals of the rheumatic diseases

authors： Badley EM,Wagstaff S,Wood PH

更新日期：1984-08-01 00:00:00

abstract：OBJECTIVES:(1) To compare clinical outcome and symptomatology of rheumatoid cervical myelopathy between patients managed conservatively and surgically. (2) To determine if surgical outcome has improved since the series published from this unit in 1987. (3) To examine the role of magnetic resonance imaging (MRI) in the ...

journal_title：Annals of the rheumatic diseases

authors： Hamilton JD,Gordon MM,McInnes IB,Johnston RA,Madhok R,Capell HA

更新日期：2000-06-01 00:00:00

abstract：OBJECTIVE:To conduct a cross-sectional review of non-selected consecutive outpatients with rheumatoid arthritis (RA) as part of standard clinical care in 15 countries for an overview of the characteristics of patients with RA. METHODS:The review included current disease activity using data from clinical assessment and...

journal_title：Annals of the rheumatic diseases

authors： Sokka T,Kautiainen H,Toloza S,Mäkinen H,Verstappen SM,Lund Hetland M,Naranjo A,Baecklund E,Herborn G,Rau R,Cazzato M,Gossec L,Skakic V,Gogus F,Sierakowski S,Bresnihan B,Taylor P,McClinton C,Pincus T,QUEST-RA Group.

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Primary Sjögren's syndrome (pSS) is characterised by a chronic inflammation of exocrine glands. Salivary gland infiltrates, however, do not correlate well with disease symptoms, and a primary role for the salivary gland parenchyma in disease development has been suggested. Specifically, dysfunction of exocri...

journal_title：Annals of the rheumatic diseases

authors： Appel S,Le Hellard S,Bruland O,Brun JG,Omdal R,Kristjansdottir G,Theander E,Nordmark G,Kvarnström M,Eriksson P,Rönnblom L,Wahren-Herlenius M,Jonsson R

更新日期：2011-07-01 00:00:00

abstract：:To establish the prevalence of inflammatory bowel disease in ankylosing spondylitis (AS), 79 AS patients underwent detailed medical screening, including sigmoidoscopic and roentgenological examination, 48 had gastrointestinal symptoms and the others did not. In 3 patients a diagnosis of Crohn's disease was made which ...

journal_title：Annals of the rheumatic diseases

authors： Meuwissen SG,Dekker-Saeys BJ,Agenant D,Tytgat GN

更新日期：1978-02-01 00:00:00

abstract：:A patient with rheumatoid arthritis (RA), vasculitis, and aortic valve incompetence of the histologically nonspecific type is described. Valve replacement was undertaken, and an excellent haemodynamic result was achieved. Both arthritis and vasculitis subsequently remitted. Valve replacement can be successfully perfor...

journal_title：Annals of the rheumatic diseases

authors： Liew M,Wilson D,Horton D,Fleming A

更新日期：1979-10-01 00:00:00

abstract：BACKGROUND:Systemic lupus erythematosus (SLE) is characterised by the presence of antibodies to double stranded DNA (dsDNA), which are involved in the pathogenesis of SLE. Previous studies showed that at least two thirds of patients develop a clinical relapse within six months after a significant rise in the anti-dsDNA...

journal_title：Annals of the rheumatic diseases

authors： Bijl M,Horst G,Bootsma H,Limburg PC,Kallenberg CG

更新日期：2003-06-01 00:00:00

abstract：OBJECTIVES:To investigate the effect of Janus kinase inhibitors (Jakinibs) on cardiovascular risk in adult patients with rheumatoid arthritis (RA) via a meta-analysis of randomised controlled trials (RCTs). METHODS:PubMed, Embase and Cochrane library were thoroughly searched for RCTs reporting safety issues in patient...

journal_title：Annals of the rheumatic diseases

authors： Xie W,Huang Y,Xiao S,Sun X,Fan Y,Zhang Z

更新日期：2019-08-01 00:00:00

abstract：:The radiographic changes of ankylosing spondylitis were studied in 50 females and 82 males. There was a tendency for the males to have more severe arthritic changes in the sacroiliac joints than the females, but the difference did not reach statistical significance. Males significantly more often had radiological invo...

journal_title：Annals of the rheumatic diseases

authors： Gran JT,Husby G,Hordvik M,Størmer J,Romberg-Andersen O

更新日期：1984-08-01 00:00:00

abstract：:Thermography before and after joint irrigation at arthroscopy showed no significant improvement of inflammation in 14 patients. Subjectively, those with chondrocalcinosis did best. ...

journal_title：Annals of the rheumatic diseases

authors： Bird HA,Ring EF

更新日期：1978-02-01 00:00:00

abstract：:Three aspects of polymorphonuclear leucocyte (PMN) function were studied in 19 patients with Behçet's syndrome (BS). By 2 different techniques directed motility was found to be increased. This increase was largely due to the subgroup of patients with ocular involvement. Counts of absolute numbers of cells migrating hi...

journal_title：Annals of the rheumatic diseases

authors： Fordham JN,Davies PG,Kirk A,Currey HL

更新日期：1982-08-01 00:00:00

abstract：OBJECTIVES:Rheumatoid factor (RF) and anti-cyclic citrullinated protein/peptide antibodies (ACPA) are integrated in the 2010 American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) classification criteria for rheumatoid arthritis (RA). The objectives of this study were to evaluate the technical ...

journal_title：Annals of the rheumatic diseases

authors： Van Hoovels L,Jacobs J,Vander Cruyssen B,Van den Bremt S,Verschueren P,Bossuyt X

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:To determine the incremental cost-effectiveness ratios (ICERs) of two therapeutic regimens of infliximab for ankylosing spondylitis (AS). METHODS:230 patients with active AS who were participating in a randomised controlled trial comparing two infliximab infusion modalities-every 6 weeks (Q6) and on demand (...

journal_title：Annals of the rheumatic diseases

authors： Fautrel B,Benhamou M,Breban M,Roy C,Lenoir C,Trape G,Baleydier A,Ravaud P,Dougados M

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVE:To assess associations between joint-specific hand symptoms and self-reported and performance-based functional status. METHODS:Participants were from the population-based Johnston County Osteoarthritis Project. Symptoms in the distal interphalangeal (DIP), proximal interphalangeal (PIP), first carpometacarpa...

journal_title：Annals of the rheumatic diseases

authors： Elliott AL,Kraus VB,Fang F,Renner JB,Schwartz TA,Salazar A,Huguenin T,Hochberg MC,Helmick CG,Jordan JM

更新日期：2007-12-01 00:00:00

abstract：OBJECTIVE:To define the relationship between autoantigen citrullination and different peptidylarginine deiminase (PAD) enzymes in rheumatoid arthritis (RA). METHODS:Citrullinated autoantigens were identified by immunoblotting control and ionomycin-activated human primary neutrophil lysate with RA sera. Autoantigen ide...

journal_title：Annals of the rheumatic diseases

authors： Darrah E,Rosen A,Giles JT,Andrade F

更新日期：2012-01-01 00:00:00

abstract：:Arthralgias have previously been reported in association with acne fulminans, but the following case in the first report of osseous lesions associated with this disease. The destructive bony lesion was rapid in onset but self-limited. ...

journal_title：Annals of the rheumatic diseases

authors： Hunter LY,Hensinger RN

更新日期：1980-08-01 00:00:00

abstract：OBJECTIVE:To examine the effects of smoking on cartilage loss and pain at the knee in individuals with knee osteoarthritis. METHODS:159 men with symptomatic knee osteoarthritis who participated in a 30-month, prospective, natural history study of knee osteoarthritis were examined. The more symptomatic knee was imaged ...

journal_title：Annals of the rheumatic diseases

authors： Amin S,Niu J,Guermazi A,Grigoryan M,Hunter DJ,Clancy M,LaValley MP,Genant HK,Felson DT

更新日期：2007-01-01 00:00:00

abstract：:An attempt was made to ascertain whether intra-articular corticosteroids exert a harmful effect on primate cartilage. The knee joints of 10 Macaca irus monkeys were subjected to either one, two, or six injections of 20 mg methyl prednisolone or an equal number of control injections over a 12-week period. Minor degener...

journal_title：Annals of the rheumatic diseases

authors： Gibson T,Burry HC,Poswillo D,Glass J

更新日期：1977-02-01 00:00:00

abstract：BACKGROUND:Small studies have linked α1 antitrypsin (α1AT) deficiency to patients with antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV). OBJECTIVE:To test the validity and the mechanism of this association between α1AT and AAV. METHODS:The distribution of α1AT deficiency alleles Z and S was co...

journal_title：Annals of the rheumatic diseases

authors： Morris H,Morgan MD,Wood AM,Smith SW,Ekeowa UI,Herrmann K,Holle JU,Guillevin L,Lomas DA,Perez J,Pusey CD,Salama AD,Stockley R,Wieczorek S,McKnight AJ,Maxwell AP,Miranda E,Williams J,Savage CO,Harper L

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVE:To evaluate radiographic features of osteoarthritis (OA) to determine which is more closely associated with knee pain and hence might be used as a radiographic definition of OA in the community. To evaluate joint space width in normal subjects. METHODS:452 subjects from a case-control community study of knee...

journal_title：Annals of the rheumatic diseases

authors： Lanyon P,O'Reilly S,Jones A,Doherty M

更新日期：1998-10-01 00:00:00

abstract：OBJECTIVE:To evaluate the ability of ultrasound (US) to detect the presence and change of Achilles erosions in spondyloarthritis (SpA). METHODS:A blind prospective two-dimensional (2D) and three-dimensional (3D) US study of Achilles enthesis erosions in early SpA was undertaken. US examinations were performed at basel...

journal_title：Annals of the rheumatic diseases

authors： de Miguel E,Falcao S,Castillo C,Plasencia C,García M,Branco JC,Martín-Mola E

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Since approval of tocilizumab (TCZ) for treatment of rheumatoid arthritis (RA) and juvenile idiopathic arthritis (JIA), interleukin 6 (IL-6) pathway inhibition was evaluated in trials of TCZ and other agents targeting the IL-6 receptor and ligand in various RA populations and other inflammatory diseases. Thi...

journal_title：Annals of the rheumatic diseases

authors： Smolen JS,Schoels MM,Nishimoto N,Breedveld FC,Burmester GR,Dougados M,Emery P,Ferraccioli G,Gabay C,Gibofsky A,Gomez-Reino JJ,Jones G,Kvien TK,Murakami M,Betteridge N,Bingham CO 3rd,Bykerk V,Choy EH,Combe B,Cutolo M

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:To determine the serum levels of nucleosome in patients with systemic sclerosis (SSc) and relate the results to the clinical features of SSc. METHODS:Serum nucleosome levels in 91 patients with SSc were examined by ELISA. The expression of Toll-like receptor (TLR) 9 in T and B cells was quantified by flow cy...

journal_title：Annals of the rheumatic diseases

authors： Yoshizaki A,Taniguchi T,Saigusa R,Fukasawa T,Ebata S,Numajiri H,Nakamura K,Yamashita T,Takahashi T,Toyama T,Asano Y,Tedder TF,Sato S

更新日期：2016-10-01 00:00:00

abstract：:While rheumatoid-factor-producing haemolytic plaque-forming cells (RF--PFC) of the human peripheral blood were easily inhibited by cycloheximide, mouse spleen cells immune to sheep red cells (anti-SRC PFC) were inhibited only after prolonged preincubation in the drug. The RF--PFC were easily inhibited by propranolol, ...

journal_title：Annals of the rheumatic diseases

authors： Moore TL,Rose JE,Vaughan JH

更新日期：1979-06-01 00:00:00

abstract：OBJECTIVE:To evaluate the safety, efficacy and therapeutic mechanism of BI 655064, an antagonistic anti-CD40 monoclonal antibody, in patients with rheumatoid arthritis (RA) and an inadequate response to methotrexate (MTX-IR). METHODS:In total, 67 patients were randomised to receive weekly subcutaneous doses of 120 mg ...

journal_title：Annals of the rheumatic diseases

authors： Visvanathan S,Daniluk S,Ptaszyński R,Müller-Ladner U,Ramanujam M,Rosenstock B,Eleftheraki AG,Vinisko R,Petříková A,Kellner H,Dokoupilova E,Kwiatkowska B,Alten R,Schwabe C,Baum P,Joseph D,Fine JS,Padula SJ,Steffgen J

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVE:To assess the expression of ICAM1, VCAM1, E-selectin, CD44, and TNF alpha in labial salivary glands of patients with rheumatoid vasculitis. METHODS:Labial salivary glands from six patients with rheumatoid vasculitis before and after treatment, six aged matched rheumatoid arthritis patients without clinical e...

journal_title：Annals of the rheumatic diseases

authors： Flipo RM,Cardon T,Copin MC,Vandecandelaere M,Duquesnoy B,Janin A

更新日期：1997-01-01 00:00:00

abstract：OBJECTIVE:To develop and validate new classification criteria for adult and juvenile idiopathic inflammatory myopathies (IIM) and their major subgroups. METHODS:Candidate variables were assembled from published criteria and expert opinion using consensus methodology. Data were collected from 47 rheumatology, dermatolo...

journal_title：Annals of the rheumatic diseases

authors： Lundberg IE,Tjärnlund A,Bottai M,Werth VP,Pilkington C,Visser M,Alfredsson L,Amato AA,Barohn RJ,Liang MH,Singh JA,Aggarwal R,Arnardottir S,Chinoy H,Cooper RG,Dankó K,Dimachkie MM,Feldman BM,Torre IG,Gordon P,Hayas

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Oral glucosamine preparations are widely used as a treatment for osteoarthritis, purportedly functioning by a variety of mechanisms suggested by results of in vitro experiments, and generally using glucosamine concentrations well in excess of 100 micromol/l. OBJECTIVE:To use high performance liquid chromato...

journal_title：Annals of the rheumatic diseases

authors： Biggee BA,Blinn CM,McAlindon TE,Nuite M,Silbert JE

更新日期：2006-02-01 00:00:00

abstract：OBJECTIVE:To assess the safety and effectiveness of imatinib mesylate in the treatment of diffuse cutaneous systemic sclerosis (dcSSc). METHODS:In this phase IIa, open-label, single-arm clinical trial, 30 patients with dcSSc were treated with imatinib 400 mg daily. Patients were monitored monthly for safety assessment...

journal_title：Annals of the rheumatic diseases

authors： Spiera RF,Gordon JK,Mersten JN,Magro CM,Mehta M,Wildman HF,Kloiber S,Kirou KA,Lyman S,Crow MK

更新日期：2011-06-01 00:00:00