Impact of Janus kinase inhibitors on risk of cardiovascular events in patients with rheumatoid arthritis: systematic review and meta-analysis of randomised controlled trials.

abstract：OBJECTIVE:To study the association between the occurrence of peripheral arthritis and of acute anterior uveitis during the course of ankylosing spondylitis (AS). METHODS:Retrospective clinical follow up by both chart review and direct patient interview was performed on 271 individuals comprised of 222 local white and ...

journal_title：Annals of the rheumatic diseases

authors： Maksymowych WP,Chou CT,Russell AS

更新日期：1995-02-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that ankylosing spondylitis (AS) is a T helper cell type 2 polarised disease by quantifying the T cell cytokines interferon gamma (IFNgamma), interleukin 4 (IL4), tumour necrosis factor alpha (TNFalpha), and IL10 at the single cell level in patients with AS in comparison with healthy HL...

journal_title：Annals of the rheumatic diseases

authors： Rudwaleit M,Siegert S,Yin Z,Eick J,Thiel A,Radbruch A,Sieper J,Braun J

更新日期：2001-01-01 00:00:00

abstract：:Three patients are presented who sustained bilateral rupture of the Achilles tendon while on systemic steroid therapy for chest disease; a fourth patient with polymyalgia rheumatica on steroids is also presented. This is further evidence that tendon rupture can be a direct complication of steroid treatment. The Englis...

journal_title：Annals of the rheumatic diseases

authors： Haines JF

更新日期：1983-12-01 00:00:00

abstract：OBJECTIVES:Evidence suggests that doxycycline might have disease-modifying properties in osteoarthritis. However, the clinically relevant question as to whether doxycycline also modifies symptoms in knee osteoarthritis is unanswered. The objective of this study was to investigate the effectiveness of doxycycline on pai...

journal_title：Annals of the rheumatic diseases

authors： Snijders GF,van den Ende CH,van Riel PL,van den Hoogen FH,den Broeder AA,NOAC study group.

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVE:To investigate anti-apoptogenic mechanism of transforming growth factor beta1 (TGFbeta1) towards synovial cells. METHODS:Isolated synovial cells, treated or not with TGFbeta1, were cultured in the presence or absence of anti-Fas IgM, proteasome inhibitor Z-Leu-Leu-Leu-aldehyde (LLL-CHO), etoposide, or C2-cer...

journal_title：Annals of the rheumatic diseases

authors： Kawakami A,Urayama S,Yamasaki S,Hida A,Miyashita T,Kamachi M,Nakashima K,Tanaka F,Ida H,Kawabe Y,Aoyagi T,Furuichi I,Migita K,Origuchi T,Eguchi K

更新日期：2004-01-01 00:00:00

abstract：:The case is reported of a 41 year old white woman who developed systemic lupus erythematosus (SLE) seven years after primary Sjögren's syndrome and four years after the association of Sjögren's syndrome with Jaccoud's arthritis. The SLE was detected by a benign intracranial hypertension, which is a rare neuro-ophthalm...

journal_title：Annals of the rheumatic diseases

authors： Chevalier X,de Bandt M,Bourgeois P,Kahn MF

更新日期：1992-06-01 00:00:00

abstract：BACKGROUND:Analysis of salivary variables has frequently been proposed as a diagnostic tool for Sjögren's syndrome (SS). Because univocal salivary reference values are lacking, it is currently rather difficult to use sialometry and sialochemistry for diagnosing SS unless major changes have occurred in salivary secretio...

journal_title：Annals of the rheumatic diseases

authors： Kalk WW,Vissink A,Stegenga B,Bootsma H,Nieuw Amerongen AV,Kallenberg CG

更新日期：2002-02-01 00:00:00

abstract：OBJECTIVE:To develop and validate new classification criteria for adult and juvenile idiopathic inflammatory myopathies (IIM) and their major subgroups. METHODS:Candidate variables were assembled from published criteria and expert opinion using consensus methodology. Data were collected from 47 rheumatology, dermatolo...

journal_title：Annals of the rheumatic diseases

authors： Lundberg IE,Tjärnlund A,Bottai M,Werth VP,Pilkington C,Visser M,Alfredsson L,Amato AA,Barohn RJ,Liang MH,Singh JA,Aggarwal R,Arnardottir S,Chinoy H,Cooper RG,Dankó K,Dimachkie MM,Feldman BM,Torre IG,Gordon P,Hayas

更新日期：2017-12-01 00:00:00

abstract：:Defined antinuclear antibodies (ANA), such as antibodies to Ro/SS-A, La/SS-B, Sm, and nRNP, are often present in serum samples from patients with systemic lupus erythematosus (SLE) or other connective tissue diseases (CTD). Most data on associations between the presence of these antibodies and defined disease features...

journal_title：Annals of the rheumatic diseases

authors： Swaak AJ,Huysen V,Smeenk RJ

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:While it is now clear that paracetamol is ineffective for spinal pain, there is not consensus on the efficacy of non-steroidal anti-inflammatory drugs (NSAIDs) for this condition. We performed a systematic review with meta-analysis to determine the efficacy and safety of NSAIDs for spinal pain. METHODS:We s...

journal_title：Annals of the rheumatic diseases

authors： Machado GC,Maher CG,Ferreira PH,Day RO,Pinheiro MB,Ferreira ML

更新日期：2017-07-01 00:00:00

abstract：:One hundred consecutive admissions to an acute geriatric unit were examined for clinical and radiographic evidence of osteoarthritis (OA) and articular chondrocalcinosis (ACC). Thirty-four patients had ACC. This was age related, the prevalence rising from 15% in patients aged 65-74 years to 44% in patients over 84 yea...

journal_title：Annals of the rheumatic diseases

authors： Wilkins E,Dieppe P,Maddison P,Evison G

更新日期：1983-06-01 00:00:00

abstract：BACKGROUND:Soluble E-selectin (sE-selectin) is a marker of activation of vascular endothelium. OBJECTIVE:To examine serum levels of sE-selectin in a cohort of 85 patients with early rheumatoid arthritis (RA) followed up for five years. METHODS:sE-selectin levels were assessed annually using an enzyme linked immunosor...

journal_title：Annals of the rheumatic diseases

authors： Kuuliala A,Eberhardt K,Takala A,Kautiainen H,Repo H,Leirisalo-Repo M

更新日期：2002-03-01 00:00:00

abstract：:Hereditary deficiencies of early complement components have usually been associated with the development of rheumatic diseases like systemic lupus erythematosus (SLE), while terminal component deficiency is well known to predispose to recurrent neisserial infection. In contrast, only recently have patients been report...

journal_title：Annals of the rheumatic diseases

authors： Wisnieski JJ,Naff GB,Pensky J,Sorin SB

更新日期：1985-10-01 00:00:00

abstract：OBJECTIVES:To investigate the presence and functionality of oestrogen receptor alpha (ERalpha) in interleukin (IL)1beta-treated rabbit articular chondrocytes in culture, and to determine the mechanisms of 17beta oestradiol (E2) effects on IL1beta-induced inducible nitric oxide synthase (iNOS) expression. METHODS:The p...

journal_title：Annals of the rheumatic diseases

authors： Richette P,Dumontier MF,Tahiri K,Widerak M,Torre A,Benallaoua M,Rannou F,Corvol MT,Savouret JF

更新日期：2007-03-01 00:00:00

abstract：OBJECTIVE:High resolution ultrasound (HRUS) was used to investigate the effects of tumour necrosis factor alpha (TNFalpha) blockade on pannus formation and vascularisation of small finger joints in patients with active rheumatoid arthritis (RA). METHODS:Five patients with active RA were treated with etanercept, a solu...

journal_title：Annals of the rheumatic diseases

authors： Hau M,Kneitz C,Tony HP,Keberle M,Jahns R,Jenett M

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVES:To characterise optimal screening strategies for latent tuberculosis infection (LTBI) prior to the initiation of anti-tumour necrosis factor therapy. METHODS:Patients in 62 German rheumatology centres were evaluated for LTBI. Each patient was screened with a tuberculin skin test (TST) and one form of an int...

journal_title：Annals of the rheumatic diseases

authors： Kleinert S,Tony HP,Krueger K,Detert J,Mielke F,Rockwitz K,Schwenke R,Burmester GR,Diel R,Feuchtenberger M,Kneitz C

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVE:To elucidate factors involved in the arthritogenicity of bacterial cell walls. METHODS:For characterisation of an arthritogenic Eubacterium aerofaciens cell wall, peptidoglycan-polysaccharide (PG-PS) polymers were isolated by removing cell wall associated proteins (CWPs), PG and PS moieties were separated, a...

journal_title：Annals of the rheumatic diseases

authors： Zhang X,Rimpiläinen M,Simelyte E,Toivanen P

更新日期：2001-03-01 00:00:00

abstract：OBJECTIVE:To compare two plain radiographic methods for sensitivity to detect progression of patellofemoral osteoarthritis. METHODS:Two sets of paired skyline and lateral knee radiographs from 54 hospital referred patients (108 knees) with knee osteoarthritis were taken an average of 31 months apart (range 12-40). Fil...

journal_title：Annals of the rheumatic diseases

authors： Lanyon P,Jones A,Doherty M

更新日期：1996-12-01 00:00:00

abstract：:A 49 year old man is described with a polyarticular arthritis. Synovial fluid aspirated from the knee joint showed monosodium urate monohydrate and calcium pyrophosphate dihydrate by polarised light microscopy. Additionally, diphosphonate binding and scanning electron microscopy with energy dispersive analysis showed ...

journal_title：Annals of the rheumatic diseases

authors： Halverson PB,Ryan LM

更新日期：1988-10-01 00:00:00

abstract：OBJECTIVE:Calprotectin is a major leucocyte protein, shown to correlate well with laboratory and clinical assessments in several inflammatory rheumatic diseases, and large concentrations of calprotectin have been found in synovial fluid from patients with rheumatoid arthritis (RA). The objective of the present study wa...

journal_title：Annals of the rheumatic diseases

authors： Hammer HB,Odegard S,Fagerhol MK,Landewé R,van der Heijde D,Uhlig T,Mowinckel P,Kvien TK

更新日期：2007-08-01 00:00:00

abstract：:Only a minority (7/35, 20%) of synovial fluids from patients with rheumatoid arthritis (RA) and none from patients with other arthritides stimulated the oxidative response of polymorphonuclear leucocytes (PMNs). Superoxide anion generation was measured by superoxide dismutase inhibitable reduction of cytochrome c. The...

journal_title：Annals of the rheumatic diseases

authors： Dularay B,Badesha JS,Dieppe PA,Elson CJ

更新日期：1990-09-01 00:00:00

abstract：OBJECTIVES:To examine the long term prognosis in patients with fibromyalgia (FM). METHODS:Forty five of 70 patients who had participated in a three week trial six years earlier completed again the same questionnaires used previously. RESULTS:Most symptoms had remained stable. Pain had increased, but some aspects of q...

journal_title：Annals of the rheumatic diseases

authors： Baumgartner E,Finckh A,Cedraschi C,Vischer TL

更新日期：2002-07-01 00:00:00

abstract：OBJECTIVE:To investigate the role of CD8 cell subsets in the pathogenesis of rheumatoid arthritis (RA) and the phenotypes of T cells adherent or non-adherent to the target cells (endothelial cells and synovial cells) pre-treated with IL-1 beta. METHODS:The expression of S6F1 on CD8 cells and that of an activation mark...

journal_title：Annals of the rheumatic diseases

authors： Ueki Y,Eguchi K,Miyake S,Nagataki S,Tominaga Y

更新日期：1994-12-01 00:00:00

abstract：OBJECTIVE:To determine the association between changes in the delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) index over 2 years as a measure of cartilage proteoglycan concentration, with changes in cartilage thickness in the medial tibiofemoral compartment of knees in middle-aged women. METHODS:One hundred and...

journal_title：Annals of the rheumatic diseases

authors： Crema MD,Hunter DJ,Burstein D,Roemer FW,Li L,Eckstein F,Krishnan N,Hellio Le-Graverand MP,Guermazi A

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Bone erosion is a common manifestation of chronic tophaceous gout. OBJECTIVES:To investigate the effects of monosodium urate monohydrate (MSU) crystals on osteoblast viability and function. METHODS:The MTT assay and flow cytometry were used to assess osteoblast cell viability in the MC3T3-E1 and ST2 osteob...

journal_title：Annals of the rheumatic diseases

authors： Chhana A,Callon KE,Pool B,Naot D,Watson M,Gamble GD,McQueen FM,Cornish J,Dalbeth N

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVE:Based upon findings in juvenile idiopathic arthritis, the genetic contribution of the VTCN1 region to rheumatoid arthritis (RA) susceptibility and anticitrullinated protein antibody (ACPA) status was investigated. VTCN1 is known to play a pivotal role in regulation of the immune system and, in soluble form, h...

journal_title：Annals of the rheumatic diseases

authors： Daha NA,Lie BA,Trouw LA,Stoeken G,Schonkeren JJ,Ding B,Kvien TK,Schilham MW,Padyukov L,Huizinga TW,Toes R

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Progression of joint destruction in rheumatoid arthritis (RA) is partly heritable; knowledge of genetic factors may increase our understanding of the mechanisms underlying joint destruction. The activity of the Wnt/β-catenin pathway influences osteoblast differentiation. Dickkopf-1 (Dkk-1) and sclerostin (So...

journal_title：Annals of the rheumatic diseases

authors： de Rooy DP,Yeremenko NG,Wilson AG,Knevel R,Lindqvist E,Saxne T,Krabben A,Leijsma MK,Daha NA,Tsonaka S,Zhernakova A,Houwing-Duistermaat JJ,Huizinga TW,Toes RE,Baeten DL,Brouwer E,van der Helm-van Mil AH

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVES:To investigate whether anti-Saccharomyces cerevisiae antibodies (ASCA), a marker for Crohn's disease (CD), are present in spondyloarthropathies (SpA) and in the subgroups ankylosing spondylitis (AS), undifferentiated SpA (uSpA), and psoriatic arthritis (PsA), in comparison with healthy and inflammatory contr...

journal_title：Annals of the rheumatic diseases

authors： Hoffman IE,Demetter P,Peeters M,De Vos M,Mielants H,Veys EM,De Keyser F

更新日期：2003-05-01 00:00:00

abstract：AIMS:The aim of this work was to assess the feasibility of using dynamic contrast enhanced (DCE) MRI of bone marrow oedema, to compare it with conventional marrow oedema scoring systems, and to determine the effects of anti-tumour necrosis factor (TNF)alpha therapy. METHODS:The wrist and metacarpophalangeal (MCP) join...

journal_title：Annals of the rheumatic diseases

authors： Hodgson R,Grainger A,O'Connor P,Barnes T,Connolly S,Moots R

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:The pathogenesis of the early stages of hand osteoarthritis is poorly understood, but recent high-resolution magnetic resonance imaging (hrMRI) studies suggest that the joint ligaments have a major role in the phenotypic expression of the disease. OBJECTIVE:To combine hrMRI and cadaveric histological studie...

journal_title：Annals of the rheumatic diseases

authors： Tan AL,Toumi H,Benjamin M,Grainger AJ,Tanner SF,Emery P,McGonagle D

更新日期：2006-10-01 00:00:00