Association of changes in delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) with changes in cartilage thickness in the medial tibiofemoral compartment of the knee: a 2 year follow-up study using 3.0 T MRI.

abstract：OBJECTIVE:To evaluate the role of interleukin 6 (IL-6) in the pathogenesis of bilateral erosive sacroiliitis in human tumour necrosis factor transgenic (hTNFtg) mice, an animal model of ankylosing spondylitis (AS). METHODS:Histological sections of the sacroiliac joints from hTNFtg and IL-6(-/-)hTNFtg mice were evaluat...

journal_title：Annals of the rheumatic diseases

authors： Hayer S,Niederreiter B,Nagelreiter I,Smolen J,Redlich K

更新日期：2010-07-01 00:00:00

abstract：:The presence of anergy and its relationship to malnutrition was investigated in patients with rheumatoid arthritis (RA) and in controls. A generalised reduction in delayed cutaneous hypersensitivity to 7 recall antigens were found in 104 RA patients compared with 67 controls. No measured of the disease was capable of ...

journal_title：Annals of the rheumatic diseases

authors： Emery P,Panayi G,Symmons D,Brown G

更新日期：1984-06-01 00:00:00

abstract：OBJECTIVE:To compare median nerve conduction velocity measured using a new, portable electroneurometer with measurements made using conventional hospital nerve conduction apparatus. METHODS:Twenty five patients were studied who were consecutively referred to a hospital neurophysiology department with a clinical diagno...

journal_title：Annals of the rheumatic diseases

authors： Dunne CA,Thompson PW,Cole J,Dunning J,Martyn CN,Coggon D,Cooper C

更新日期：1996-06-01 00:00:00

abstract：OBJECTIVES:To estimate the incidence of postinfectious joint complaints after Campylobacter jejuni/coli enteritis compared with enteritis caused by enterotoxigenic E coli (ETEC). To compare gastrointestinal symptoms, antibiotic treatment, and antibody levels among patients with and without joint symptoms. METHOD:Quest...

journal_title：Annals of the rheumatic diseases

authors： Locht H,Krogfelt KA

更新日期：2002-05-01 00:00:00

abstract：OBJECTIVE:Etanercept monotherapy has been studied and approved for treatment of polyarticular juvenile idiopathic arthritis (JIA). The following study evaluates the safety and efficacy of combination therapy of etanercept and methotrexate compared to etanercept monotherapy in JIA. METHODS:We perfomed an open, non-rand...

journal_title：Annals of the rheumatic diseases

authors： Horneff G,De Bock F,Foeldvari I,Girschick HJ,Michels H,Moebius D,Schmeling H,German and Austrian Paediatric Rheumatology Collaborative Study Group.

更新日期：2009-04-01 00:00:00

abstract：:Polyclonal anticardiolipin antibodies purified from pooled serum samples of patients with systemic lupus erythematosus were shown to have inhibitory effects on cultured normal rat brain astrocytes (RBA-1 cells). Anticardiolipin antibodies at concentrations from 50 to 200 micrograms/ml inhibited the [3H]thymidine incor...

journal_title：Annals of the rheumatic diseases

authors： Sun KH,Liu WT,Tsai CY,Liao TS,Lin WM,Yu CL

更新日期：1992-06-01 00:00:00

abstract：BACKGROUND:PATIENTS with rheumatoid arthritis (RA) are at increased risk of developing comorbid conditions. OBJECTIVES:To evaluate the prevalence of comorbidities and compare their management in RA patients from different countries worldwide. METHODS: STUDY DESIGN:international, cross-sectional. PATIENTS:consecutiv...

journal_title：Annals of the rheumatic diseases

authors： Dougados M,Soubrier M,Antunez A,Balint P,Balsa A,Buch MH,Casado G,Detert J,El-Zorkany B,Emery P,Hajjaj-Hassouni N,Harigai M,Luo SF,Kurucz R,Maciel G,Mola EM,Montecucco CM,McInnes I,Radner H,Smolen JS,Song YW,Von

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To study maternal and fetal outcome of pregnancy in patients with lupus who were exposed to hydroxychloroquine (HCQ). METHODS:The case records of women (n = 33) exposed to HCQ during their pregnancies (n = 36) and of 53 control patients from a single lupus pregnancy centre were reviewed to determine lupus ac...

journal_title：Annals of the rheumatic diseases

authors： Buchanan NM,Toubi E,Khamashta MA,Lima F,Kerslake S,Hughes GR

更新日期：1996-07-01 00:00:00

abstract：BACKGROUND:Several studies have reported an association between the presence of the shared epitope (SE) and susceptibility to rheumatoid arthritis (RA). Recent studies have shown that certain HLA-DRB1 alleles in combination with predisposing DQB1 and DQA1 alleles may protect against the development of RA. This model is...

journal_title：Annals of the rheumatic diseases

authors： Molenaar ET,Voskuyl AE,van der Horst-Bruinsma IE,Schreuder GM,Zanelli E,Dijkmans BA

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:High rheumatoid arthritis (RA) disease activity during pregnancy is associated with a lower birth weight. Active RA is characterised by high circulating levels of cytokines, which can mediate placental growth and remodelling. OBJECTIVES:To assess the influence of maternal serum cytokine levels on birth weig...

journal_title：Annals of the rheumatic diseases

authors： de Steenwinkel FD,Hokken-Koelega AC,de Man YA,de Rijke YB,de Ridder MA,Hazes JM,Dolhain RJ

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:To investigate the sympathetic and parasympathetic cardiovascular function in primary Sjögren's syndrome (SS) and to investigate the possible relation with ocular dryness. METHODS:41 (40 women) patients with primary SS, mean age 50 years (range 20-80) with a mean disease duration of eight years (range 1-30),...

journal_title：Annals of the rheumatic diseases

authors： Barendregt PJ,van Den Meiracker AH,Markusse HM,Tulen JH,Boomsma F,van Der Heijde GL,Veld AJ

更新日期：1999-12-01 00:00:00

abstract：OBJECTIVES:To describe patients with autoimmune inflammatory rheumatic diseases (AIRD) who had COVID-19 disease; to compare patients who required hospital admission with those who did not and assess risk factors for hospital admission related to COVID-19. METHODS:An observational longitudinal study was conducted durin...

journal_title：Annals of the rheumatic diseases

authors： Freites Nuñez DD,Leon L,Mucientes A,Rodriguez-Rodriguez L,Font Urgelles J,Madrid García A,Colomer JI,Jover JA,Fernandez-Gutierrez B,Abasolo L

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:Based upon findings in juvenile idiopathic arthritis, the genetic contribution of the VTCN1 region to rheumatoid arthritis (RA) susceptibility and anticitrullinated protein antibody (ACPA) status was investigated. VTCN1 is known to play a pivotal role in regulation of the immune system and, in soluble form, h...

journal_title：Annals of the rheumatic diseases

authors： Daha NA,Lie BA,Trouw LA,Stoeken G,Schonkeren JJ,Ding B,Kvien TK,Schilham MW,Padyukov L,Huizinga TW,Toes R

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVES:To determine concentrations of chondroitin sulphate (CS) and keratan sulphate (KS) epitopes, glycosaminoglycans (GAGs) and hyaluronan (HA) in knee synovial fluid (SF) from normal subjects and patients with osteoarthritis (OA) or rheumatoid arthritis (RA), to test whether these variables may be used as marker...

journal_title：Annals of the rheumatic diseases

authors： Belcher C,Yaqub R,Fawthrop F,Bayliss M,Doherty M

更新日期：1997-05-01 00:00:00

abstract：OBJECTIVE:To assess sensory function in skin overlying the joints of patients with rheumatoid arthritis, in relation to the pain and tenderness which commonly arises in structures not directly involved in the inflammatory process. METHODS:An intradermal injection of capsaicin 0.05 microgram in 10 microliters was made ...

journal_title：Annals of the rheumatic diseases

authors： Jolliffe VA,Anand P,Kidd BL

更新日期：1995-04-01 00:00:00

abstract：OBJECTIVE:To study immunological markers and compare these markers with standard measures for the clinical and immunological follow up of vasculitis activity in hepatitis C virus (HCV) associated cryoglobulinaemic vasculitis (CV). METHODS:Serial serum samples from eight patients with newly diagnosed HCV associated CV ...

journal_title：Annals of the rheumatic diseases

authors： Lamprecht P,Moosig F,Gause A,Herlyn K,Csernok E,Hansen H,Gross WL

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:Certain sequences present in the hypervariable region of human leucocyte antigen (HLA)-DRB1 known as the shared epitope (SE) are hypothesised to increase the risk of rheumatoid arthritis (RA), whereas alleles encoding aspartic acid at position 70 (D70 alleles) may have a protective effect. METHODS:Patient H...

journal_title：Annals of the rheumatic diseases

authors： Shadick NA,Heller JE,Weinblatt ME,Maher NE,Cui J,Ginsburg G,Coblyn J,Anderson R,Solomon DH,Roubenoff R,Parker A

更新日期：2007-11-01 00:00:00

abstract：:Two British secondary schools (one a specialist music school) were surveyed to assess the prevalence of upper limb pain among specialist music students compared with students in a regular school setting. Female students tended to report pain more often than male students, but for both significantly higher prevalence w...

journal_title：Annals of the rheumatic diseases

authors： Fry HJ,Rowley GL

更新日期：1989-12-01 00:00:00

abstract：:Two patients are described with severe and progressive rheumatoid arthritis in whom methotrexate was reintroduced despite previous methotrexate related pneumonitis. In both patients a marked improvement in disease control occurred without a recurrence of the pneumonitis. ...

journal_title：Annals of the rheumatic diseases

authors： Cook NJ,Carroll GJ

更新日期：1992-02-01 00:00:00

abstract：:The possible contribution of immunological mechanisms in the development of Libman-Sacks endocarditis was studied in 2 patients with systemic lupus erythematosus who underwent aortic valve replacement. Sections of verrucous lesions, stained with haematoxylin and eosin, showed three apparently distinct zones: an outer ...

journal_title：Annals of the rheumatic diseases

authors： Shapiro RF,Gamble CN,Wiesner KB,Castles JJ,Wolf AW,Hurley EJ,Salel AF

更新日期：1977-12-01 00:00:00

abstract：:Concanavalin-A-induced T-suppressor cell activity was decreased in spleen cell suspensions from Lewis rats with adjuvant arthritis. This decreased activity was evident on day 10 after the induction of the disease, just before the development of the polyarthritic lesions, and persisted during the period of active infla...

journal_title：Annals of the rheumatic diseases

authors： Binderup L

更新日期：1983-12-01 00:00:00

abstract：:Twenty seven patients with primary or possible Sjögren's syndrome with neurological manifestations were compared immunologically with 21 patients with Sjögren's syndrome with an intact nervous system. Patients with Sjögren's syndrome were divided into seropositive and seronegative subgroups with respect to the occurre...

journal_title：Annals of the rheumatic diseases

authors： Hietaharju A,Korpela M,Ilonen J,Frey H

更新日期：1992-04-01 00:00:00

abstract：OBJECTIVES:To analyse the association between chondrocalcinosis and osteoarthritis (OA) of the hands and knees in an unselected elderly rural population. METHODS:A community based cross sectional study was performed in individuals randomly selected from a previous epidemiological survey on the prevalence of chondrocal...

journal_title：Annals of the rheumatic diseases

authors： Sanmarti R,Kanterewicz E,Pladevall M,Pañella D,Tarradellas JB,Gomez JM

更新日期：1996-01-01 00:00:00

abstract：OBJECTIVES:Previous evidence suggests the role of psychological stress in triggering the onset of autoimmunity. We aimed to investigate whether stress following major and minor life events could precede the onset of primary Sjögren's syndrome (pSS). The role of coping strategies and social support, as compensating buff...

journal_title：Annals of the rheumatic diseases

authors： Karaiskos D,Mavragani CP,Makaroni S,Zinzaras E,Voulgarelis M,Rabavilas A,Moutsopoulos HM

更新日期：2009-01-01 00:00:00

abstract：:The early changes (five weeks) in the structure of newly synthesised and endogenous articular cartilage sulphated proteoglycans were studied in lapine IgG induced experimental immune synovitis. Rabbits with immune synovitis (IS-IgG) were compared with animals with a developed hypersensitivity to IgG (I-IgG) and with n...

journal_title：Annals of the rheumatic diseases

authors： Malemud CJ,Yoo JU,Goldberg VM,Kresina TF

更新日期：1987-07-01 00:00:00

abstract：:An acute inflammatory arthritis has been induced in 76% of rats injected intradermally with native bovine type II collagen emulsified in Freund's complete (CFA) or incomplete (ICFA) adjuvant. The arthritis became chronic in 14 out of 31 rats, and ear and tail lesions were noted in some rats. No arthritis was induced b...

journal_title：Annals of the rheumatic diseases

authors： Morgan K,Clague RB,Shaw MJ,Holt PJ

更新日期：1980-06-01 00:00:00

abstract：:Previous work has suggested that prior poor reproductive outcome may be a risk factor in rheumatoid arthritis (RA). A case-control study of 195 women with RA and 462 control women from two different sources is presented here. No increase in rates of spontaneous abortion was seen in the women with RA; indeed a protecti...

journal_title：Annals of the rheumatic diseases

authors： Spector TD,Silman AJ

更新日期：1990-01-01 00:00:00

abstract：QUESTION:Which is the best strategy to achieve (drug-free) inactive disease in juvenile idiopathic arthritis (JIA)? METHODS:In a randomised, single-blinded, study in disease-modifying anti-rheumatic drug (DMARD)-naive patients with JIA, three treatment-strategies were compared: (1) sequential DMARD-monotherapy (sulfas...

journal_title：Annals of the rheumatic diseases

authors： Hissink Muller P,Brinkman DMC,Schonenberg-Meinema D,van den Bosch WB,Koopman-Keemink Y,Brederije ICJ,Bekkering PW,Kuijpers TW,Van Rossum M,van Suijlekom-Smit LWA,van den Berg JM,Boehringer S,Allaart CF,Ten Cate R

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Although natural regulatory T cells (nTregs) can suppress osteoclastogenesis, the role of TGF-β-induced CD4+Foxp3+ Tregs (iTregs) in osteoclastogenesis remains unknown. OBJECTIVE:To determine the effects of iTregs on osteoclastogenesis in vitro and on bone erosion in vivo in collagen-induced arthritis (CIA)...

journal_title：Annals of the rheumatic diseases

authors： Kong N,Lan Q,Su W,Chen M,Wang J,Yang Z,Park R,Dagliyan G,Conti PS,Brand D,Liu Z,Stohl W,Zou H,Zheng SG

更新日期：2012-09-01 00:00:00

abstract：:This paper reports the spontaneous development of synovitis in 'Old English' rabbits concurrent with serum IgM rheumatoid factor. Female rabbits developed lesions at a higher incidence than males (42% compared with 17%) and the pathology was of a more severe nature. In the female rabbits synovitis was associated with ...

journal_title：Annals of the rheumatic diseases

authors： Hanglow AC,Welsh CJ,Conn P,Thomas DS,Coombs RR

更新日期：1986-04-01 00:00:00