Decreased T-suppressor cell activity in rats with adjuvant arthritis.

abstract：OBJECTIVE:To determine whether occurrence, characteristics, and progression of systemic lupus erythematosus (SLE) are associated with polymorphism of the mannose binding lectin (MBL) gene and with serum MBL concentration. METHODS:Codon 54 MBL gene polymorphism of 147 patients with SLE and 160 healthy controls was dete...

journal_title：Annals of the rheumatic diseases

authors： Takahashi R,Tsutsumi A,Ohtani K,Muraki Y,Goto D,Matsumoto I,Wakamiya N,Sumida T

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVES:To characterise renal tissue metabolic pathway gene expression in different forms of glomerulonephritis. METHODS:Patients with nephrotic syndrome (NS), antineutrophil cytoplasmic antibody-associated vasculitis (AAV), systemic lupus erythematosus (SLE) and healthy living donors (LD) were studied. Clinically ...

journal_title：Annals of the rheumatic diseases

authors： Grayson PC,Eddy S,Taroni JN,Lightfoot YL,Mariani L,Parikh H,Lindenmeyer MT,Ju W,Greene CS,Godfrey B,Cohen CD,Krischer J,Kretzler M,Merkel PA,Vasculitis Clinical Research Consortium, the European Renal cDNA Bank cohort, and th

更新日期：2018-08-01 00:00:00

abstract：PURPOSE:To assess risk of cartilage loss in the tibiofemoral joint in relation to baseline damage severity, and to analyse the association of nearby pathologic findings on the risk of subsequent cartilage loss. METHODS:The Multicenter Osteoarthritis Study is a longitudinal study of individuals with or at high risk for...

journal_title：Annals of the rheumatic diseases

authors： Roemer FW,Felson DT,Wang K,Crema MD,Neogi T,Zhang Y,Nevitt MC,Marra MD,Lewis CE,Torner J,Guermazi A,MOST study investigators.

更新日期：2013-06-01 00:00:00

abstract：:Thirty-three patients with early peripheral synovitis were followed up for two to four years in order to study the relationship between fluctuations in rheumatoid factor (RF) levels and indices of clinical activity. Twenty-eight of these patients developed classical/definite rheumatoid arthritis (RA). Seventeen patien...

journal_title：Annals of the rheumatic diseases

authors： Withrington RH,Teitsson I,Valdimarsson H,Seifert MH

更新日期：1984-10-01 00:00:00

abstract：OBJECTIVES:To describe presentation and outcome of patients with scleroderma renal crisis (SRC). METHODS:SRC was defined as rapidly progressive oliguric renal insufficiency and/or rapidly progressive arterial hypertension occurring during the course of systemic sclerosis (SSc). Chronic dialysis-free survival was analy...

journal_title：Annals of the rheumatic diseases

authors： Teixeira L,Mouthon L,Mahr A,Berezné A,Agard C,Mehrenberger M,Noël LH,Trolliet P,Frances C,Cabane J,Guillevin L,Group Français de Recherche sur le Sclérodermie (GFRS).

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Anti-citrullinated protein antibodies (ACPAs) are the hallmark of rheumatoid arthritis (RA). Protein citrullination is believed to drive autoantigen selection in RA. Nonetheless, several autoantigens in RA are targeted as native (unmodified) proteins. Here, the study of hnRNP A2/B1 (RA33) provides a framewor...

journal_title：Annals of the rheumatic diseases

authors： Konig MF,Giles JT,Nigrovic PA,Andrade F

更新日期：2016-11-01 00:00:00

abstract：:Hereditary deficiencies of early complement components have usually been associated with the development of rheumatic diseases like systemic lupus erythematosus (SLE), while terminal component deficiency is well known to predispose to recurrent neisserial infection. In contrast, only recently have patients been report...

journal_title：Annals of the rheumatic diseases

authors： Wisnieski JJ,Naff GB,Pensky J,Sorin SB

更新日期：1985-10-01 00:00:00

abstract：OBJECTIVES:Symptomatic knee osteoarthritis (OA) is a common disabling condition. Attention has tended to focus on the tibiofemoral joint (TFJ). However, there is evidence that the patellofemoral joint (PFJ) is involved in many cases, but its place in the sequence of development and progression of knee OA is unclear. Th...

journal_title：Annals of the rheumatic diseases

authors： Duncan R,Peat G,Thomas E,Hay EM,Croft P

更新日期：2011-11-01 00:00:00

abstract：:The case presented is of a patient with migratory polyarthritis and serological evidence of a recent streptococcal infection, consistent with the diagnosis of acute rheumatic fever, who in addition had multisystem disease manifestations. This case supports the concept that the sequelae of streptococcal infection can e...

journal_title：Annals of the rheumatic diseases

authors： Livneh A,Sharma K,Sewell KL,Keiser HD

更新日期：1991-05-01 00:00:00

abstract：OBJECTIVE:To study the association between silica exposure, separately as well as combined with smoking, and the risk of developing rheumatoid arthritis (RA) with or without the presence of antibodies against citrullinated peptide antigens (ACPA). METHODS:This Swedish population based case-control study analysed 577 i...

journal_title：Annals of the rheumatic diseases

authors： Stolt P,Yahya A,Bengtsson C,Källberg H,Rönnelid J,Lundberg I,Klareskog L,Alfredsson L,EIRA Study Group.

更新日期：2010-06-01 00:00:00

abstract：:The aim of this report was to propose a definition for erosive disease in the context of inflammatory arthritis in light of the 2010 American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) rheumatoid arthritis (RA) criteria for use in clinical practice and studies. A EULAR task force was form...

journal_title：Annals of the rheumatic diseases

authors： van der Heijde D,van der Helm-van Mil AH,Aletaha D,Bingham CO,Burmester GR,Dougados M,Emery P,Felson D,Knevel R,Kvien TK,Landewé RB,Lukas C,McInnes I,Silman AJ,Smolen JS,Stanislawska-Biernat E,Zink A,Combe B

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Cancellous bone from patients with osteoarthritis (OA) has been reported to be undermineralised and that from patients with osteoporosis (OP) is more liable to fracture. Changes in the mineral component might be implicated in these processes. OBJECTIVES:To investigate the thermal stability and the mineral s...

journal_title：Annals of the rheumatic diseases

authors： Mkukuma LD,Imrie CT,Skakle JM,Hukins DW,Aspden RM

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVE:Although genome-wide association studies (GWAS) have identified approximately 100 loci for rheumatoid arthritis (RA), the disease mechanisms are not completely understood. We evaluated the pathogenesis of RA by focusing on rare coding variants. METHODS:The coding regions of 98 candidate genes identified by G...

journal_title：Annals of the rheumatic diseases

authors： Motegi T,Kochi Y,Matsuda K,Kubo M,Yamamoto K,Momozawa Y

更新日期：2019-08-01 00:00:00

abstract：OBJECTIVE:To assess the incremental diagnostic value of spine MRI evaluated separately from and combined with sacroiliac joint (SIJ) MRI in non-radiographic axial spondyloarthritis (nr-axSpA) compared with SIJ MRI alone. METHODS:The study sample comprised two independent cohorts A/B of 130 consecutive patients aged ≤5...

journal_title：Annals of the rheumatic diseases

authors： Weber U,Zubler V,Zhao Z,Lambert RG,Chan SM,Pedersen SJ,Østergaard M,Rufibach K,Maksymowych WP

更新日期：2015-06-01 00:00:00

abstract：:Pulmonary hypertension in systemic lupus erythematosus (SLE) is rare in the absence of parenchymal lung disease. We report such a case, which was complicated by the subsequent development of a left recurrent laryngeal nerve palsy, and in which there was a strong family history of SLE. ...

journal_title：Annals of the rheumatic diseases

authors： Aszkenasy OM,Clarke TJ,Hickling P,Marshall AJ

更新日期：1987-03-01 00:00:00

abstract：:The radiographic changes of ankylosing spondylitis were studied in 50 females and 82 males. There was a tendency for the males to have more severe arthritic changes in the sacroiliac joints than the females, but the difference did not reach statistical significance. Males significantly more often had radiological invo...

journal_title：Annals of the rheumatic diseases

authors： Gran JT,Husby G,Hordvik M,Størmer J,Romberg-Andersen O

更新日期：1984-08-01 00:00:00

abstract：OBJECTIVES:To evaluate the risk of septic arthritis (SA) in patients with rheumatoid arthritis (RA) treated with anti-tumour necrosis factor (TNF) therapy. METHODS:Using data from the British Society for Rheumatology Biologics Register, a prospective observational study, the authors compared the risk of SA between 11 ...

journal_title：Annals of the rheumatic diseases

authors： Galloway JB,Hyrich KL,Mercer LK,Dixon WG,Ustianowski AP,Helbert M,Watson KD,Lunt M,Symmons DP,BSR Biologics Register.

更新日期：2011-10-01 00:00:00

abstract：:To identify the local factors in cartilage that are responsible for the induction of pannus invasion, a 14 day organ culture study in which rheumatoid synovium was grown in contact with cartilage pieces was carried out. Rheumatoid synovium preferentially extended over hyaluronidase treated cartilage pieces, but detach...

journal_title：Annals of the rheumatic diseases

authors： Shiozawa S,Yoshihara R,Kuroki Y,Fujita T,Shiozawa K,Imura S

更新日期：1992-07-01 00:00:00

abstract：:A patient with systemic lupus erythematosus who developed pneumococcal epiglottitis is described and the literature reviewed. This infection is extremely rare in adults, and only 10 cases, none of them with SLE, have so far been reported. Epiglottitis is usually caused by Haemophilus influenzae. However, in immunocomp...

journal_title：Annals of the rheumatic diseases

authors： Shalit M,Gross DJ,Levo Y

更新日期：1982-12-01 00:00:00

abstract：OBJECTIVES:To assess the prevalence and patterns of cardiac abnormalities as detected by cardiac magnetic resonance imaging (MRI) in systemic sclerosis (SSc). METHODS:Fifty-two consecutive patients with SSc underwent cardiac MRI to determine morphological, functional, perfusion at rest and delayed enhancement abnormal...

journal_title：Annals of the rheumatic diseases

authors： Hachulla AL,Launay D,Gaxotte V,de Groote P,Lamblin N,Devos P,Hatron PY,Beregi JP,Hachulla E

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVES:Annual echocardiography screening is widely used in scleroderma, but the utility of longitudinal assessment is unknown. We evaluated whether change in right ventricular systolic pressure (RVSP) was a risk factor for mortality and development of pulmonary arterial hypertension (PAH) in a cohort of scleroderma...

journal_title：Annals of the rheumatic diseases

authors： Shah AA,Chung SE,Wigley FM,Wise RA,Hummers LK

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Human leucocyte antigen (HLA) genes predict disease severity in psoriasis (HLA-Cw6) and rheumatoid arthritis (shared epitope (SE)), but the situation is unclear for psoriatic arthritis (PsA). AIM:To determine the association of the HLA-Cw6 and HLA-DRB1 gene with disease severity in a large UK cohort with Ps...

journal_title：Annals of the rheumatic diseases

authors： Ho PY,Barton A,Worthington J,Thomson W,Silman AJ,Bruce IN

更新日期：2007-06-01 00:00:00

abstract：:A 17-year-old female patient with systemic lupus erythematosus (SLE) developed chronic tophaceous gout, chondrocalcinosis and articular capsule calcification in several joints. Analysis of synovial fluid and tophi revealed the coexistence of monosodium urate, calcium pyrophosphate, hydroxyapatite, and cholesterol crys...

journal_title：Annals of the rheumatic diseases

authors： Rodríguez MA,Paul H,Abadí I,Bravo JR,Armas P

更新日期：1984-06-01 00:00:00

abstract：:Polymorphonuclear leucocytes (PMNs), which predominate in inflammatory synovial fluid, can degrade cartilage. This was measured by a novel in vitro model; PMNs were incubated for up to one hour with 2 or 3 microns sections of cartilage and the glycosaminoglycan loss determined by microdensitometry after alcian blue st...

journal_title：Annals of the rheumatic diseases

authors： Moore AR,Iwamura H,Larbre JP,Scott DL,Willoughby DA

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVES:Systemic sclerosis (SSc) is a rare disease requiring multicentre collaboration to reveal comprehensive details of disease-related causes for morbidity and mortality. METHODS:The European League Against Rheumatism (EULAR) Scleroderma Trials and Research (EUSTAR) group initiated a database to prospectively ga...

journal_title：Annals of the rheumatic diseases

authors： Meier FM,Frommer KW,Dinser R,Walker UA,Czirjak L,Denton CP,Allanore Y,Distler O,Riemekasten G,Valentini G,Müller-Ladner U,EUSTAR Co-authors.

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Chondromalacia patellae is a potentially disabling disorder characterised by features of patellar cartilage degradation. OBJECTIVE:To evaluate markers of cartilage and bone turnover in patients with chondromalacia patellae. METHODS:18 patients with chondromalacia patellae were studied. Serum cartilage olig...

journal_title：Annals of the rheumatic diseases

authors： Murphy E,FitzGerald O,Saxne T,Bresnihan B

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:Increased apoptosis may induce autoimmune conditions. Apoptosis is induced by binding of death receptor ligands, members of the tumour necrosis factor (TNF) superfamily, to their cognate receptors. The Fas-Fas ligand pathway has been studied extensively in relation to systemic lupus erythematosus (SLE). Howe...

journal_title：Annals of the rheumatic diseases

authors： Lub-de Hooge MN,de Vries EG,de Jong S,Bijl M

更新日期：2005-06-01 00:00:00

abstract：:A method is described for evaluating the progress of patients with back pain. Various symptoms were scored on analogue scales and spinal motion was measured by various techniques. These data were integrated to make subjective and objective indices respectively. Reasonable reproducibility of the measurements was obtain...

journal_title：Annals of the rheumatic diseases

authors： Million R,Nilsen KH,Jayson MI,Baker RD

更新日期：1981-10-01 00:00:00

abstract：:In a search for aspects of behaviour related to oral contraceptive use which might explain the favourable effect of oral contraception on the onset of rheumatoid arthritis (RA), cigarette smoking and alcohol consumption were studied as possible risk factors. Information on cigarette smoking and alcohol consumption was...

journal_title：Annals of the rheumatic diseases

authors： Hazes JM,Dijkmans BA,Vandenbroucke JP,de Vries RR,Cats A

更新日期：1990-12-01 00:00:00

abstract：:A 35 year old woman presented with headache and fever. Computed brain tomography showed diffuse low attenuation in the cerebral white matter. Several months later, serological tests for systemic lupus erythematosus (SLE) became positive. In spite of immunosuppressive therapy she relapsed after six months of treatment,...

journal_title：Annals of the rheumatic diseases

authors： Boulter M,Brink A,Mathias C,Peart S,Stevens J,Stewart G,Unwin R

更新日期：1987-02-01 00:00:00