Primary Sjögren's syndrome preceding the presentation of systemic lupus erythematosus as a benign intracranial hypertension syndrome.

abstract：:The regression of small rheumatoid nodules was noted in four patients after starting sulphasalazine therapy. This coincided with an improvement in synovitis and also falls in erythrocyte sedimentation rate (ESR) and C reactive protein (CRP). The relation between the nodule regression and the sulphasalazine therapy is ...

journal_title：Annals of the rheumatic diseases

authors： Englert HJ,Hughes GR,Walport MJ

更新日期：1987-03-01 00:00:00

abstract：PURPOSE:IL-23 has been shown to be involved in the pathogenesis of Behcet's disease (BD) through promoting IL-17 production. This study examined whether IL-23R polymorphisms were associated with susceptibility to this disease in a Chinese Han population. METHODS:Four single-nucleotide polymorphisms (SNP), rs7517847, r...

journal_title：Annals of the rheumatic diseases

authors： Jiang Z,Yang P,Hou S,Du L,Xie L,Zhou H,Kijlstra A

更新日期：2010-07-01 00:00:00

abstract：OBJECTIVES:The severity of joint destruction is highly variable between rheumatoid arthritis (RA) patients. The majority of its heritability is still unexplained. Several autoimmune diseases share genetic risk variants that may also influence disease progression. We aimed to identify genetic risk factors for the severi...

journal_title：Annals of the rheumatic diseases

authors： de Rooy DP,Zhernakova A,Tsonaka R,Willemze A,Kurreeman BA,Trynka G,van Toorn L,Toes RE,Huizinga TW,Houwing-Duistermaat JJ,Gregersen PK,van der Helm-van Mil AH

更新日期：2014-06-01 00:00:00

abstract：:The case is described of a 57 year old woman with polyarthritis fulfilling the 1987 revised criteria of the American Rheumatism Association for rheumatoid arthritis, accompanied by clinical carrier state infection of HTLV-I. Anti-HTLV-I IgM antibodies were detected by western blot analysis in her synovial fluid and se...

journal_title：Annals of the rheumatic diseases

authors： Ijichi S,Matsuda T,Maruyama I,Izumihara T,Kojima K,Niimura T,Maruyama Y,Sonoda S,Yoshida A,Osame M

更新日期：1990-09-01 00:00:00

abstract：:A patient with systemic lupus erythematosus who developed pneumococcal epiglottitis is described and the literature reviewed. This infection is extremely rare in adults, and only 10 cases, none of them with SLE, have so far been reported. Epiglottitis is usually caused by Haemophilus influenzae. However, in immunocomp...

journal_title：Annals of the rheumatic diseases

authors： Shalit M,Gross DJ,Levo Y

更新日期：1982-12-01 00:00:00

abstract：:A 46 year old man presented with a growing mass over his wrist. Erosions of the triquetrum and hamate were present radiographically. Magnetic resonance imaging (MRI) showed a solid mass arising from the extensor carpi ulnaris tendon, which was T(1) hypointense and isointense, T(2) hypointense, and bloomed on gradient ...

journal_title：Annals of the rheumatic diseases

authors： Peh WC,Shek TW,Ip WY

更新日期：2001-06-01 00:00:00

abstract：BACKGROUND:Human leucocyte antigen (HLA) genes predict disease severity in psoriasis (HLA-Cw6) and rheumatoid arthritis (shared epitope (SE)), but the situation is unclear for psoriatic arthritis (PsA). AIM:To determine the association of the HLA-Cw6 and HLA-DRB1 gene with disease severity in a large UK cohort with Ps...

journal_title：Annals of the rheumatic diseases

authors： Ho PY,Barton A,Worthington J,Thomson W,Silman AJ,Bruce IN

更新日期：2007-06-01 00:00:00

abstract：:An explant method for the isolation of fibroblasts from adult human tendon is described. Cells were successfully isolated from 22 out of 27 common biceps tendons obtained from cadaveric donors (age range 11-83 years). The fibroblasts could be maintained in culture using standard methods and morphologically resembled t...

journal_title：Annals of the rheumatic diseases

authors： Chard MD,Wright JK,Hazleman BL

更新日期：1987-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy and safety of adding sulfasalazine to leflunomide treatment compared with switching to sulfasalazine alone in patients with RA with an inadequate response to leflunomide monotherapy. METHODS:Patients with active RA ((DAS28) >3.2) who were enrolled in the first open label phase of the...

journal_title：Annals of the rheumatic diseases

authors： Dougados M,Emery P,Lemmel EM,Zerbini CA,Brin S,van Riel P

更新日期：2005-01-01 00:00:00

abstract：:Osteotomies on 101 knees in 79 patients were assessed either prospectively or retrospectively. High tibial osteotomy was performed in 54 knees (27 with rheumatoid arthritis (RA) and 27 with osteoarthrosis (OA)) and double (tibiofemoral) osteotomy in 47 knees (25 RA and 22 OA), and were assessed prospectively in 46 and...

journal_title：Annals of the rheumatic diseases

authors： Iveson JM,Longton EB,Wright V

更新日期：1977-08-01 00:00:00

abstract：BACKGROUND:Mast cells have been implicated in the pathogenesis of arthritis, but elucidation of their precise role has been hampered by a lack of efficient and selective inhibitors of their function. OBJECTIVE:To elucidate the role of mast cells in the pathogenesis of rheumatoid arthritis (RA) and to assess whether ap...

journal_title：Annals of the rheumatic diseases

authors： Juurikivi A,Sandler C,Lindstedt KA,Kovanen PT,Juutilainen T,Leskinen MJ,Mäki T,Eklund KK

更新日期：2005-08-01 00:00:00

abstract：OBJECTIVE:To investigate the association between baseline serum adipokines levels-leptin, adiponectin and resistin-and long-term progression of hand osteoarthritis (HOA). METHODS:Baseline and 6-year radiographs of 164 patients (mean age 60 years, 81% women) with HOA (defined as a Kellgren and Lawrence score ≥2 in at l...

journal_title：Annals of the rheumatic diseases

authors： Yusuf E,Ioan-Facsinay A,Bijsterbosch J,Klein-Wieringa I,Kwekkeboom J,Slagboom PE,Huizinga TW,Kloppenburg M

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVES:MRI scoring systems for hand osteoarthritis (HOA) are currently not available. The present work proposes the Oslo HOA MRI (OHOA-MRI) score and examines the intrareader and inter-reader reliability. METHODS:Relevant HOA features were included in the initial version of the OHOA-MRI score after literature revi...

journal_title：Annals of the rheumatic diseases

authors： Haugen IK,Lillegraven S,Slatkowsky-Christensen B,Haavardsholm EA,Sesseng S,Kvien TK,van der Heijde D,Bøyesen P

更新日期：2011-06-01 00:00:00

abstract：:Current drug development programs produce high quality data on the efficacy of new drugs, substantial data on safety, but little data on actual applicability of the new product compared to standard of care. After successful registration and launch, such data require years to accumulate and often remain incomplete. Thi...

journal_title：Annals of the rheumatic diseases

authors： Boers M

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:The study aim was to examine the B lymphocyte stimulator (BLyS) receptor-ligand system in hepatitis C virus (HCV)-induced B lymphocyte clonal disorders. METHODS:94 patients with chronic HCV (including 35 with HCV+ mixed cryoglobulinaemia (MC)-vasculitis and nine with HCV+ B cell non-Hodgkin's lymphoma (B-NHL...

journal_title：Annals of the rheumatic diseases

authors： Landau DA,Rosenzwajg M,Saadoun D,Klatzmann D,Cacoub P

更新日期：2009-03-01 00:00:00

abstract：:Four patients with Neisseria meningitidis infection complicated by arthritis are described. Three patients had an acute polyarthritis which responded quickly to antimicrobial therapy. A fourth patient developed a prolonged arthritis which occurred after the initial infection had been successfully treated. Tenosynoviti...

journal_title：Annals of the rheumatic diseases

authors： Kidd BL,Hart HH,Grigor RR

更新日期：1985-11-01 00:00:00

abstract：OBJECTIVES:To compare patterns of arteriographic lesions of the aorta and primary branches in patients with Takayasu's arteritis (TAK) and giant cell arteritis (GCA). METHODS:Patients were selected from two North American cohorts of TAK and GCA. The frequency of arteriographic lesions was calculated for 15 large arter...

journal_title：Annals of the rheumatic diseases

authors： Grayson PC,Maksimowicz-McKinnon K,Clark TM,Tomasson G,Cuthbertson D,Carette S,Khalidi NA,Langford CA,Monach PA,Seo P,Warrington KJ,Ytterberg SR,Hoffman GS,Merkel PA,Vasculitis Clinical Research Consortium.

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVE:To determine whether occurrence, characteristics, and progression of systemic lupus erythematosus (SLE) are associated with polymorphism of the mannose binding lectin (MBL) gene and with serum MBL concentration. METHODS:Codon 54 MBL gene polymorphism of 147 patients with SLE and 160 healthy controls was dete...

journal_title：Annals of the rheumatic diseases

authors： Takahashi R,Tsutsumi A,Ohtani K,Muraki Y,Goto D,Matsumoto I,Wakamiya N,Sumida T

更新日期：2005-02-01 00:00:00

abstract：:A three phase study was designed to define further the sensitivity and specificity of symptomatic salicylate ototoxicity (primarily tinnitus) for serum salicylate concentrations. In phase one 260 patients with osteoarthritis and 112 with rheumatoid arthritis, none taking salicylates, were interviewed about their ear s...

journal_title：Annals of the rheumatic diseases

authors： Halla JT,Atchison SL,Hardin JG

更新日期：1991-10-01 00:00:00

abstract：BACKGROUND:PATIENTS with rheumatoid arthritis (RA) are at increased risk of developing comorbid conditions. OBJECTIVES:To evaluate the prevalence of comorbidities and compare their management in RA patients from different countries worldwide. METHODS: STUDY DESIGN:international, cross-sectional. PATIENTS:consecutiv...

journal_title：Annals of the rheumatic diseases

authors： Dougados M,Soubrier M,Antunez A,Balint P,Balsa A,Buch MH,Casado G,Detert J,El-Zorkany B,Emery P,Hajjaj-Hassouni N,Harigai M,Luo SF,Kurucz R,Maciel G,Mola EM,Montecucco CM,McInnes I,Radner H,Smolen JS,Song YW,Von

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To better understand the characteristics of synoviocytes located in the rheumatoid arthritis (RA) pannus. METHODS:One cell line, termed PSC, was cloned from RA pannus lesions. Phenotypic analysis was done by contrast microscopy, indirect immunostaining, and safranin O staining. Transcription of several proto...

journal_title：Annals of the rheumatic diseases

authors： Xue C,Takahashi M,Hasunuma T,Aono H,Yamamoto K,Yoshino S,Sumida T,Nishioka K

更新日期：1997-04-01 00:00:00

abstract：:False positive results were obtained for HIV tests in two men with active systemic lupus erythematosus (SLE) who were suspected of being infected with HIV because of fever, weight loss, lymphadenopathy, and inflammatory myopathy. Enzyme linked immunosorbent assays (ELISAs) for HIV were twice positive when tested three...

journal_title：Annals of the rheumatic diseases

authors： Esteva MH,Blasini AM,Ogly D,Rodríguez MA

更新日期：1992-09-01 00:00:00

abstract：:A patient with systemic lupus erythematosus was first diagnosed after she had developed the Budd-Chiari syndrome. We believe that the Budd-Chiari syndrome was part of her tendency for thrombosis, induced by the presence of a lupus anticoagulant. The association between enhanced thrombosis and the lupus anticoagulant i...

journal_title：Annals of the rheumatic diseases

authors： Averbuch M,Levo Y

更新日期：1986-05-01 00:00:00

abstract：OBJECTIVES:The balance between interferon gamma (IFN gamma) and interleukin 4 (IL4) producing T cells (T1 and T2 cells) seems to be of importance in many (auto)immune disorders. In general, T1 cell activity is important in cellular immunity whereas T2 cell activity plays a part in humoral responses. T1 cell activity pr...

journal_title：Annals of the rheumatic diseases

authors： Verhoef CM,van Roon JA,Vianen ME,Bruijnzeel-Koomen CA,Lafeber FP,Bijlsma JW

更新日期：1998-05-01 00:00:00

abstract：OBJECTIVES:The aim of this pilot study was to compare clinical examination (CE) and ultrasound (US) with high field MRI (as the reference standard) for the detection of rearfoot and midtarsal joint synovitis and secondly tenosynovitis of the ankle tendons in patients with established rheumatoid arthritis (RA). METHODS...

journal_title：Annals of the rheumatic diseases

authors： Wakefield RJ,Freeston JE,O'Connor P,Reay N,Budgen A,Hensor EM,Helliwell PS,Emery P,Woodburn J

更新日期：2008-12-01 00:00:00

abstract：:Free thiomalate is measureable in the plasma and urine of patients with rheumatoid arthritis receiving sodium aurothiomalate (Myocrisin). Plasma concentrations and urinary excretion of free thiomalate were measured in 8 patients by high-performance liquid chromatography and electrochemical detection. After an initial ...

journal_title：Annals of the rheumatic diseases

authors： Rudge SR,Perrett D,Swannell AJ

更新日期：1984-02-01 00:00:00

abstract：:The complement system plays a major role in the autoimmune disease, systemic lupus erythematosus (SLE). However, the role of complement in SLE is complex since it may both prevent and exacerbate the disease. In this review, we explore the latest findings in complement-focused research in SLE. C1q deficiency is the str...

journal_title：Annals of the rheumatic diseases

authors： Leffler J,Bengtsson AA,Blom AM

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVES:Immune checkpoint inhibitors (ICIs) targeting cytotoxic T-lymphocyte-associated protein 4 and programmed cell death protein 1 (PD-1) have demonstrated improved survival for multiple cancers. However, these new drug classes have led to increased immune-related adverse events (IrAE). Rheumatic IrAEs have not b...

journal_title：Annals of the rheumatic diseases

authors： Belkhir R,Burel SL,Dunogeant L,Marabelle A,Hollebecque A,Besse B,Leary A,Voisin AL,Pontoizeau C,Coutte L,Pertuiset E,Mouterde G,Fain O,Lambotte O,Mariette X

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:A disease activity-guided dose optimisation strategy of adalimumab or etanercept (TNFi (tumour necrosis factor inhibitors)) has shown to be non-inferior in maintaining disease control in patients with rheumatoid arthritis (RA) compared with usual care. However, the cost-effectiveness of this strategy is stil...

journal_title：Annals of the rheumatic diseases

authors： Kievit W,van Herwaarden N,van den Hoogen FH,van Vollenhoven RF,Bijlsma JW,van den Bemt BJ,van der Maas A,den Broeder AA

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVE:To investigate the long-term effects of induction therapy with adalimumab (ADA) plus methotrexate (MTX) in comparison with placebo (PBO) plus MTX in DMARD-naïve patients with active early rheumatoid arthritis (RA). METHODS:Patients with active early RA (disease duration of ≤12 months) were randomly assigned ...

journal_title：Annals of the rheumatic diseases

authors： Detert J,Bastian H,Listing J,Weiß A,Wassenberg S,Liebhaber A,Rockwitz K,Alten R,Krüger K,Rau R,Simon C,Gremmelsbacher E,Braun T,Marsmann B,Höhne-Zimmer V,Egerer K,Buttgereit F,Burmester GR

更新日期：2013-06-01 00:00:00