Metabolic inhibition of plaque-forming cells: comparison of human rheumatoid-factor-producing cells with mouse anti-sheep erythrocyte-producing cells.

abstract：OBJECTIVE:Antiphospholipid antibody (aPL) specificity for aPL-related events was evaluated in systemic lupus erythematosus (SLE). METHODS:A study was carried out on 105 patients affected with SLE comparing the prevalence of lupus anticoagulant (LA) and IgG and IgM anticardiolipin antibodies (aCL) between patients with...

journal_title：Annals of the rheumatic diseases

authors： Ghirardello A,Doria A,Ruffatti A,Rigoli AM,Vesco P,Calligaro A,Gambari PF

更新日期：1994-02-01 00:00:00

abstract：:The relation of habitual knuckle cracking to osteoarthrosis with functional impairment of the hand has long been considered an old wives' tale without experimental support. The mechanical sequelae of knuckle cracking have been shown to produce the rapid release of energy in the form of sudden vibratory energy, much li...

journal_title：Annals of the rheumatic diseases

authors： Castellanos J,Axelrod D

更新日期：1990-05-01 00:00:00

abstract：:We have compared the distribution of histocompatibility antigens of 22 Turkish and 14 British patients with Behçet's disease with those of their respective controls. There was a strong association of B5, specifically its Bw51 split, with the disease. A modest increase in the incidence of HLA B27 was noted in British p...

journal_title：Annals of the rheumatic diseases

authors： Yazici H,Chamberlain MA,Schreuder I,D'Amaro J,Muftuoglu M

更新日期：1980-08-01 00:00:00

abstract：:Published case reports of chloroquine retinopathy rarely include details of daily dosage, but 30 reports where this information was available included 78 patients who developed impaired visual acuity an 13 had received daily doses of 250 mg or less. Eleven cases of ocular toxicity attributed to chloroquine were report...

journal_title：Annals of the rheumatic diseases

authors： Marks JS

更新日期：1982-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The Fc receptor-like 3 (FCRL3) gene -169T>C single nucleotide polymorphism (SNP) has been reported to be associated with several autoimmune diseases (AIDs) in Japanese populations. However, association results in other populations have been conflicting. Therefore, we investigated this SNP in a...

journal_title：Annals of the rheumatic diseases

authors： Eike MC,Nordang GB,Karlsen TH,Boberg KM,Vatn MH,IBSEN study group.,Dahl-Jørgensen K,Rønningen KS,Joner G,Flatø B,Bergquist A,Thorsby E,Førre O,Kvien TK,Undlien DE,Lie BA

更新日期：2008-09-01 00:00:00

abstract：:Using an in vitro system of cell migration from glass capillary tubes, the nonsteroidal, anti-inflammatory agents sodium salicylate, aspirin, ibuprofen, phenylbutazone, and indomethacin were shown to inhibit the migration of human peripheral leucocytes in a dose-related manner. This drug action was not confined to one...

journal_title：Annals of the rheumatic diseases

authors： Brown KA,Collins AJ

更新日期：1977-06-01 00:00:00

abstract：:The serological diagnosis of juvenile rheumatoid arthritis (JRA) is difficult, with only 7-10% of patients 19S IgM rheumatoid factor positive. About 60-70% of patients are positive for hidden 19S IgM rheumatoid factor, but this test requires serum separation and is not available in most laboratories. Antiperinuclear f...

journal_title：Annals of the rheumatic diseases

authors： Nesher G,Moore TL,Grisanti MW,el-Najdawi E,Osborn TG

更新日期：1992-03-01 00:00:00

abstract：:Purified peripheral blood polymorphonuclear leucocytes (PMNs) from patients with rheumatoid arthritis (RA) have been found to differ from purified PMNs from normal subjects in ways that are consistent with their prior activation. However, it is currently contentious whether activated PMNs really circulate in patients ...

journal_title：Annals of the rheumatic diseases

authors： McCarthy DA,Bernhagen J,Taylor MJ,Hamblin AS,James I,Thompson PW,Perry JD

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:Validation of responsiveness and discriminative power of the World Health Organisation/International League of Associations for Rheumatology (WHO/ILAR) core set, the American College of Rheumatology (ACR), and European League for Rheumatology (EULAR) criteria for improvement/response, and other single and com...

journal_title：Annals of the rheumatic diseases

authors： Verhoeven AC,Boers M,van Der Linden S

更新日期：2000-12-01 00:00:00

abstract：OBJECTIVE:High serum interferon α (IFNα) activity is a heritable risk factor for systemic lupus erythematosus (SLE). Auto-antibodies found in SLE form immune complexes which can stimulate IFNα production by activating endosomal Toll-like receptors and interferon regulatory factors (IRFs), including IRF5. Genetic variat...

journal_title：Annals of the rheumatic diseases

authors： Niewold TB,Kelly JA,Kariuki SN,Franek BS,Kumar AA,Kaufman KM,Thomas K,Walker D,Kamp S,Frost JM,Wong AK,Merrill JT,Alarcón-Riquelme ME,Tikly M,Ramsey-Goldman R,Reveille JD,Petri MA,Edberg JC,Kimberly RP,Alarcón GS,

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVES:To study the reliability and construct validity of ultrasound in interphalangeal finger joints affected by erosive osteoarthritis (EOA) and non-EOA with MRI as the reference method. METHODS:252 joints were examined by ultrasound, conventional radiography and clinical examination. Ultrasound was performed us...

journal_title：Annals of the rheumatic diseases

authors： Wittoek R,Jans L,Lambrecht V,Carron P,Verstraete K,Verbruggen G

更新日期：2011-02-01 00:00:00

abstract：:The effects of fasting for 7 days were investigated in 13 patients with rheumatoid arthritis (RA) in comparison with a control regimen in a cross-over trial. The effects of fasting on clinical performance and blood neutrophil functions were studied. During fasting, with a mean weight loss of 5.1 kg, clinical inflammat...

journal_title：Annals of the rheumatic diseases

authors： Udén AM,Trang L,Venizelos N,Palmblad J

更新日期：1983-02-01 00:00:00

abstract：OBJECTIVE:Ankylosing spondylitis (AS) and periodontal disease (PD) are characterised by dysregulation of the host inflammatory response, resulting in soft and hard connective tissue destruction. AS has been related to other inflammatory diseases, however, there is a paucity of data on whether AS is associated with infl...

journal_title：Annals of the rheumatic diseases

authors： Pischon N,Pischon T,Gülmez E,Kröger J,Purucker P,Kleber BM,Landau H,Jost-Brinkmann PG,Schlattmann P,Zernicke J,Burmester GR,Bernimoulin JP,Buttgereit F,Detert J

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVES:To evaluate the risk of septic arthritis (SA) in patients with rheumatoid arthritis (RA) treated with anti-tumour necrosis factor (TNF) therapy. METHODS:Using data from the British Society for Rheumatology Biologics Register, a prospective observational study, the authors compared the risk of SA between 11 ...

journal_title：Annals of the rheumatic diseases

authors： Galloway JB,Hyrich KL,Mercer LK,Dixon WG,Ustianowski AP,Helbert M,Watson KD,Lunt M,Symmons DP,BSR Biologics Register.

更新日期：2011-10-01 00:00:00

abstract：:The case is reported of a 41 year old white woman who developed systemic lupus erythematosus (SLE) seven years after primary Sjögren's syndrome and four years after the association of Sjögren's syndrome with Jaccoud's arthritis. The SLE was detected by a benign intracranial hypertension, which is a rare neuro-ophthalm...

journal_title：Annals of the rheumatic diseases

authors： Chevalier X,de Bandt M,Bourgeois P,Kahn MF

更新日期：1992-06-01 00:00:00

abstract：:Ten patients (8 female, 2 male) with systemic lupus erythematosus (SLE) were entered into an open trial with the anabolic steroid 19-nortestosterone (19-nor). Their clinical condition did not improve, nor were significant changes observed in the majority of laboratory data. However, overall the platelet count rose, an...

journal_title：Annals of the rheumatic diseases

authors： Hazelton RA,McCruden AB,Sturrock RD,Stimson WH

更新日期：1983-04-01 00:00:00

abstract：OBJECTIVE:The eumusc.net project is an initiative founded by the European Community and the European League Against Rheumatism. One aim of the project was to facilitate equal standards for musculoskeletal health across Europe. The aim of this work-package was to develop patient-centred and consensus based standards of ...

journal_title：Annals of the rheumatic diseases

authors： Stoffer MA,Smolen JS,Woolf A,Ambrozic A,Berghea F,Boonen A,Bosworth A,Carmona L,Dougados M,de Wit M,Erwin J,Fialka-Moser V,Ionescu R,Keenan AM,Loza E,Moe RH,Greiff R,Olejnik P,Petersson IF,Rat AC,Rozman B,Strömb

更新日期：2015-06-01 00:00:00

abstract：OBJECTIVES:To determine concentrations of chondroitin sulphate (CS) and keratan sulphate (KS) epitopes, glycosaminoglycans (GAGs) and hyaluronan (HA) in knee synovial fluid (SF) from normal subjects and patients with osteoarthritis (OA) or rheumatoid arthritis (RA), to test whether these variables may be used as marker...

journal_title：Annals of the rheumatic diseases

authors： Belcher C,Yaqub R,Fawthrop F,Bayliss M,Doherty M

更新日期：1997-05-01 00:00:00

abstract：OBJECTIVE:To determine the significance of quantitative levels of antibodies to cyclic citrullinated peptides (anti-CCP) in a population of patients with rheumatoid arthritis (RA). METHODS:A total of 241 consecutive sera from patients with RA sent from a large rheumatology clinic for laboratory testing were selected f...

journal_title：Annals of the rheumatic diseases

authors： Lee DM,Phillips R,Hagan EM,Chibnik LB,Costenbader KH,Schur PH

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVES:To assess the risk of losing remission, low disease activity (LDA) or radiographic progression in the case of (1) discontinuing or (2) tapering doses of biological disease-modifying antirheumatic drugs (bDMARDs) compared with continuation of the initial treatment regimen in rheumatoid arthritis (RA) patients...

journal_title：Annals of the rheumatic diseases

authors： Henaux S,Ruyssen-Witrand A,Cantagrel A,Barnetche T,Fautrel B,Filippi N,Lukas C,Raffeiner B,Rossini M,Degboé Y,Constantin A

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVES:To investigate the efficacy and safety of peficitinib, an oral Janus kinase inhibitor, in patients with rheumatoid arthritis (RA). METHODS:In this double-blind phase III study, patients with RA and an inadequate response to prior disease-modifying anti-rheumatic drugs (DMARDs) were randomised to peficitinib...

journal_title：Annals of the rheumatic diseases

authors： Tanaka Y,Takeuchi T,Tanaka S,Kawakami A,Iwasaki M,Song YW,Chen YH,Wei JC,Lee SH,Rokuda M,Izutsu H,Ushijima S,Kaneko Y,Akazawa R,Shiomi T,Yamada E

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVES:Systemic lupus erythematosus (SLE) is a serious multisystem autoimmune disease, mediated by disrupted B cell quiescence and typically treated with glucocorticoids. We studied whether B cells in SLE are regulated by the glucocorticoid-induced leucine zipper (GILZ) protein, an endogenous mediator of anti-infla...

journal_title：Annals of the rheumatic diseases

authors： Jones SA,Toh AE,Odobasic D,Oudin MA,Cheng Q,Lee JP,White SJ,Russ BE,Infantino S,Light A,Tarlinton DM,Harris J,Morand EF

更新日期：2016-04-01 00:00:00

abstract：:Thirty-three patients with early peripheral synovitis were followed up for two to four years in order to study the relationship between fluctuations in rheumatoid factor (RF) levels and indices of clinical activity. Twenty-eight of these patients developed classical/definite rheumatoid arthritis (RA). Seventeen patien...

journal_title：Annals of the rheumatic diseases

authors： Withrington RH,Teitsson I,Valdimarsson H,Seifert MH

更新日期：1984-10-01 00:00:00

abstract：BACKGROUND:Progression of joint destruction in rheumatoid arthritis (RA) is partly heritable; knowledge of genetic factors may increase our understanding of the mechanisms underlying joint destruction. The activity of the Wnt/β-catenin pathway influences osteoblast differentiation. Dickkopf-1 (Dkk-1) and sclerostin (So...

journal_title：Annals of the rheumatic diseases

authors： de Rooy DP,Yeremenko NG,Wilson AG,Knevel R,Lindqvist E,Saxne T,Krabben A,Leijsma MK,Daha NA,Tsonaka S,Zhernakova A,Houwing-Duistermaat JJ,Huizinga TW,Toes RE,Baeten DL,Brouwer E,van der Helm-van Mil AH

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:To investigate the possibility of drug-free remission in patients with psoriatic arthritis (PsA) in continuous remission. METHODS:Prospective observational study in disease-modifying antirheumatic drug (DMARD)-treated PsA patients in continuous disease remission (no musculoskeletal symptoms, no or minimal sk...

journal_title：Annals of the rheumatic diseases

authors： Araujo EG,Finzel S,Englbrecht M,Schreiber DA,Faustini F,Hueber A,Nas K,Rech J,Schett G

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Primary Sjögren's syndrome (pSS) is a systemic autoimmune disease characterised by aberrant B cell hyperactivation, whose mechanism is partially understood. METHODS:We performed whole transcriptome sequencing of B cells from three pSS patients and three matched healthy controls (HC). Differentially expressi...

journal_title：Annals of the rheumatic diseases

authors： Sun JL,Zhang HZ,Liu SY,Lian CF,Chen ZL,Shao TH,Zhang S,Zhao LL,He CM,Wang M,Zhang W,Chen H,Zhang FC

更新日期：2020-04-01 00:00:00

abstract：OBJECTIVE:Rheumatoid arthritis (RA) accompanies infiltration and activation of monocytes in inflamed joints. We investigated dominant alterations of RA monocytes in bone marrow (BM), blood and inflamed joints. METHODS:CD14+ cells from BM and peripheral blood (PB) of patients with RA and osteoarthritis (OA) were profil...

journal_title：Annals of the rheumatic diseases

authors： Smiljanovic B,Radzikowska A,Kuca-Warnawin E,Kurowska W,Grün JR,Stuhlmüller B,Bonin M,Schulte-Wrede U,Sörensen T,Kyogoku C,Bruns A,Hermann S,Ohrndorf S,Aupperle K,Backhaus M,Burmester GR,Radbruch A,Grützkau A,Maslinski

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVES:To study the role of two COL2A1 single nucleotide polymorphisms (rs3737548 and rs2276455) and their haplotypes in individual susceptibility to osteoarthritis (OA) of the hand in Finnish women. METHODS:Bilateral hand radiographs of 543 Finnish female dentists and teachers aged 45-63 years were examined and c...

journal_title：Annals of the rheumatic diseases

authors： Hämäläinen S,Solovieva S,Hirvonen A,Vehmas T,Takala EP,Riihimäki H,Leino-Arjas P

更新日期：2009-10-01 00:00:00

abstract：:The prostaglandin E (PGE) level in the knee joint fluid was determined by radioimmunoassay before and after anti-inflammatory therapy with flurbiprofen in 8 patients with rheumatoid arthritis (RA) and 4 patients with osteoarthritis (OA). The level of PGE in RA joint fluids before the anti-inflammatory treatment was 9....

journal_title：Annals of the rheumatic diseases

authors： Tokunaga M,Ohuchi K,Yoshizawa S,Tsurufuji S,Rikimaru A,Wakamatsu E

更新日期：1981-10-01 00:00:00

abstract：OBJECTIVE:To determine the occurrence and clinical characteristics of reactive arthritis (ReA) after an outbreak of Yersinia pseudotuberculosis serotype O:3 infection. METHODS:From 15 October to 6 November 1998, a widespread outbreak of Y pseudotuberculosis serotype O:3 occurred in Finland. A questionnaire on musculos...

journal_title：Annals of the rheumatic diseases

authors： Hannu T,Mattila L,Nuorti JP,Ruutu P,Mikkola J,Siitonen A,Leirisalo-Repo M

更新日期：2003-09-01 00:00:00