Abstract:
:Functional recovery after an experimental stroke can be assessed by multiple behavioral tests, however, there is no consensus about which test to use in long-term stroke recovery studies or whether the tests are affected by stroke surgery, post-operative care or behavioral compensation due to repeated testing. This review describes the tests most commonly used to assess motor and sensorimotor function, cognition and mood in stroke animals. Although it is difficult to predict the direction of future research, it may be possible to prevent false-positive results by selecting an appropriate task or a battery of tasks. It is also expected that the upcoming stroke recovery recommendations and the improved dialogue between academy, industry and healthcare professionals will further promote translational success.
journal_name
Behav Brain Resjournal_title
Behavioural brain researchauthors
Balkaya MG,Trueman RC,Boltze J,Corbett D,Jolkkonen Jdoi
10.1016/j.bbr.2017.07.039subject
Has Abstractpub_date
2018-10-15 00:00:00pages
161-171eissn
0166-4328issn
1872-7549pii
S0166-4328(17)30732-5journal_volume
352pub_type
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