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Mild forced treadmill exercise enhances spatial learning in the aged rat.

Abstract：

:This study addresses whether or not mild, forced treadmill exercise improves learning and increases neurotrophin levels in the basal forebrain (BF). Neurotrophin deficits in the BF have been implicated in Alzheimer's disease, and physical exercise increases neurotrophins. Aged rats exercised for 7 weeks found the hidden platform faster than controls (F(1, 10)=14.6, p<0.05), and swam shorter pathlengths (F(1, 10)=12.6, p<0.05), with no difference in swim speed. Neurotrophins did not differ.

journal_name

Behav Brain Res

journal_title

Behavioural brain research

authors

Albeck DS,Sano K,Prewitt GE,Dalton L

doi

10.1016/j.bbr.2005.11.008

subject

Has Abstract

pub_date

2006-04-03 00:00:00

pages

345-8

issue

2

eissn

0166-4328

issn

1872-7549

pii

S0166-4328(05)00487-0

journal_volume

168

pub_type

杂志文章

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