ESCRT-dependent degradation of ubiquitylated plasma membrane proteins in plants.

Abstract:

:To control the abundance of plasma membrane receptors and transporters is crucial for proper perception and response to extracellular signals from surrounding cells and the environment. Posttranslational modification of plasma membrane proteins, especially ubiquitin conjugation or ubiquitylation, is key for the determination of stability for many transmembrane proteins localized on the cell surface. The targeted degradation is ensured by a complex network of proteins among which the endosomal sorting complex required for transport (ESCRT) plays a central role. This review focuses on progresses made in recent years on the understanding of the function of the ESCRT machinery in the degradation of ubiquitylated plasma membrane proteins in plants.

journal_name

Curr Opin Plant Biol

authors

Isono E,Kalinowska K

doi

10.1016/j.pbi.2017.07.003

subject

Has Abstract

pub_date

2017-12-01 00:00:00

pages

49-55

eissn

1369-5266

issn

1879-0356

pii

S1369-5266(17)30087-0

journal_volume

40

pub_type

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