Abstract:
:Acute profound dystonia developed in three previously well infants who were found to have glutaryl-CoA dehydrogenase deficiency in cultured skin fibroblasts. Two patients had excessive urinary excretion of glutaric acid, but one did not. Neuroradiologic studies performed in all three patients at the onset of their illnesses revealed large CSF-containing spaces both within the sylvian fissures and anterior to the temporal lobes. Pathologic examination of the brain of one patient demonstrated cerebral and cerebellar atrophy, shrinkage of the putamen, and white matter vacuolation. Glutaric acidemia may be a common cause of acquired persistent dystonia or choreoathetosis in infancy.
journal_name
Pediatricsjournal_title
Pediatricsauthors
Bergman I,Finegold D,Gartner JC Jr,Zitelli BJ,Claassen D,Scarano J,Roe CR,Stanley C,Goodman SIsubject
Has Abstractpub_date
1989-02-01 00:00:00pages
228-34issue
2eissn
0031-4005issn
1098-4275journal_volume
83pub_type
杂志文章,评审相关文献
PEDIATRICS文献大全abstract::All cases of fluoride ingestion in children younger than 12 years old reported to the Rocky Mountain Poison Center between January 1 and December 31, 1986, were retrospectively reviewed. Eighty-seven cases were identified. Eighty-four cases involved accidental ingestion of dental fluoride products in the home (tablets...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1991-11-01 00:00:00
abstract::A study was done to assess the necessity of hospital care for poisoning episodes in children less than 5 years old and to evaluate the impact of a regional poison center on the use of emergency rooms for pediatric poisonings. Of the pediatric patients seen in emergency rooms for acute poisonings, 63% did not require t...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1983-08-01 00:00:00
abstract::Despite substantial progress, adolescents remain at high risk for human immunodeficiency virus (HIV) infection. Two independent random digit dial statewide Massachusetts surveys of 16- to 19-year-old persons conducted August through September 1986 and 1988 revealed that the proportion of teenagers who had discussed ac...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::Much of medical education remains teacher centered, as exemplified by the continued emphasis on lectures. Increasingly, however, the importance of the learner is being recognized and acknowledged in medical school curricula. The distinction between teaching and learning is also an issue for graduate medical education;...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1996-12-01 00:00:00
abstract::A family is described in which the father and three (and probably all four) of his children had a decreased capacity for the oxidation of medium-chain fatty acids. One of the children suddenly died at the age of 16 months following an episode of a rapidly deteriorating Reye syndrome-like illness with hypoketotic hypog...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1986-12-01 00:00:00
abstract:BACKGROUND:Identity formation and exploration of interpersonal relationships are important tasks that occur during adolescence. Transgender, gender diverse, and gender-nonconforming (TGNC) individuals must face these developmental milestones in the context of their transgender identity. Our aim with this article is to ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2020-007906
更新日期:2021-02-01 00:00:00
abstract:OBJECTIVE:The objective for this study was to characterize the impact and the safety of transporting neonates with known or suspected cardiac abnormalities. METHODS:We reviewed retrospectively the charts and computerized records of 192 admissions to a cardiac ICU in 2002. Patients were included when they were < 28 day...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2006-0719
更新日期:2006-09-01 00:00:00
abstract::To test the efficacy and safety of vitamin E in preventing retinopathy of prematurity, 287 infants with birth weights of less than 1.5 kg or gestational ages of less than 33 weeks were enrolled within 24 hours of birth in a randomized, double-masked trial of IV, followed by oral, placebo v tocopherol (adjusted to plas...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1987-04-01 00:00:00
abstract:OBJECTIVE:Our aim was to define the relationship of PaO(2) and pulse oxygen saturation values during routine clinical practice and to evaluate whether pulse oxygen saturation values between 85% and 93% were associated with PaO(2) levels of <40 mmHg. METHODS:Prospective comparison of PaO(2) and pulse oxygen saturation ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2007-0117
更新日期:2008-05-01 00:00:00
abstract::In the ideal situation, the evaluation for sepsis in the young infant should include collection of multiple blood cultures before the institution of antibiotics. Unfortunately, in some infants, it may not be possible to obtain more than a single blood culture at the time of initial evaluation. If this single culture u...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1990-08-01 00:00:00
abstract::Sedating children safely and effectively for minor laceration repair is a well-recognized clinical problem. A randomized, double-blind, and controlled study was conducted to evaluate the efficacy of intranasal midazolam for reducing stress during the suturing of lacerations in preschool children. Fifty-nine children w...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1993-03-01 00:00:00
abstract::Two types of waterbeds were developed to impart compensatory vestibular-proprioceptive stimulation to premature infants. Twenty-one infants ranging in gestational age from 27 to 34 weeks and birthweights from 1,050 to 1,920 gm were included in this pilot study. Assignment to experimental and control groups was made by...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1975-09-01 00:00:00
abstract:OBJECTIVES:In recent years there has been increasing emphasis on the mental health aspects of primary health care for children and adolescents. The Health Resources and Services Administration's Maternal and Child Health Bureau has contributed to efforts aimed at strengthening primary care not only in early identificat...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.99.4.e5
更新日期:1997-04-01 00:00:00
abstract::In Canada, 8% to 20% of infants are breast-fed by mothers who smoke. To determine whether breast-feeding increases infants' exposure to tobacco smoke products, urinary cotinine excretion was measured in 172 babies, 33 of whom were breast-fed. A milk sample was taken from the mothers who were breast-feeding, and cotini...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract:OBJECTIVE:To determine if the incidence of empyema among children in the United States has changed since the introduction of the pneumococcal conjugate vaccine in 2000. METHODS:We used the nationally representative Kids' Inpatient Database to estimate the annual total number of hospitalizations of children < or = 18 y...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2009-0184
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVE:Dental caries is a common, chronic disease of childhood. The impact of contemporary changes in beverage patterns, specifically decreased milk intakes and increased 100% juice and soda pop intakes, on dental caries in young children is unknown. We describe associations among caries experience and intakes of da...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.112.3.e184
更新日期:2003-09-01 00:00:00
abstract:BACKGROUND:Poor mental health is recognized as one of the greatest global burdens of disease. Maternal mental health is crucial for the optimal health of mothers and their children. We examined the effects of an Australian Nurse Home Visiting (NHV) program (right@home), offered to pregnant women experiencing adversity,...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2020-025361
更新日期:2021-02-01 00:00:00
abstract::In recent years, there have been significant advancements in our understanding of acute kidney injury (AKI) and its impact on outcomes across medicine. Research based on single-center cohorts suggests that neonatal AKI is very common and associated with poor outcomes. In this state-of-the-art review on neonatal AKI, w...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.2014-3819
更新日期:2015-08-01 00:00:00
abstract::A 4-year-old Jewish boy presented with dysuria, urinary dribbling, increased urinary frequency, and new onset of diurnal enuresis. An infiltrating solid mass involving the entire bladder wall was found. Biopsy revealed "tumor-forming" eosinophilic cystitis, a rare bladder lesion of unclear cause. Antitoxocariasis trea...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.108.6.e113
更新日期:2001-12-01 00:00:00
abstract::The interval from the beginning of the Q wave to the origin of the T wave (Q-oTc interval) and total and ionized serum calcium levels were measured in 27 full-term and 77 premature infants. The correlation between Q-oTc and total and ionized calcium levels was significant in both full-term and normal premature infants...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1978-06-01 00:00:00
abstract:BACKGROUND:Universal screening of sexually active adolescents for Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (GC) has been recommended in settings in which prevalence is 2% or greater. Although believed to be above 2%, the prevalence of CT and GC infection in private practice settings has not been clearly est...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.108.6.e103
更新日期:2001-12-01 00:00:00
abstract:OBJECTIVE:We investigated the relationship between prenatal exposure to dichlorodiphenyltrichloroethane (DDT) and dichlorodiphenyldichloroethylene (DDE) and neurodevelopment of Mexican farm-workers' children in California. METHODS:Participants from the Center for the Health Assessment of Mothers and Children of Salina...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2005-3117
更新日期:2006-07-01 00:00:00
abstract::This article is an examination of the nature and extent of the problem presented by medically uninsured children in the United States. First, the characteristics of the uninsured population are explored with a description of how age, family income, and employment status disproportionately affect families with children...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1990-05-01 00:00:00
abstract::: media-1vid110.1542/5972300121001PEDS-VA_2018-1771Video Abstract OBJECTIVES: To examine agreement between parent and adolescent reports of adolescents' suicidal thoughts and explore demographic and clinical factors associated with agreement in a large community sample. METHODS:Participants included 5137 adolescents ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2018-1771
更新日期:2019-02-01 00:00:00
abstract:OBJECTIVES:Patent ductus arteriosus (PDA) remains a challenging issue in very low birth weight (VLBW) infants, and its management varies widely. Our aim in this study was to document the natural course of ductus arteriosus in a cohort of VLBW infants who underwent conservative PDA management with no medical or surgical...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2016-4258
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVE:To determine correlates of sedentary behaviors in adolescents through the examination of psychosocial and environmental variables. METHOD:The study used a cross-sectional design to evaluate an ethnically diverse clinic-based sample of 878 adolescents who were 11 to 15 years old. Bivariate and multivariate an...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2004-1814
更新日期:2005-10-01 00:00:00
abstract::Adolescent and young adult (AYA) patients with cancer may face unique challenges if they and their families wish to participate in clinical oncology trials. Regulatory guidelines and funding requirements put in place to protect patients may actually raise barriers to enrollment in clinical trials. Hospital age guideli...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2014-0122H
更新日期:2014-06-01 00:00:00
abstract:OBJECTIVE:We measured physical activity changes among 10-year-old British children over 12 months and assessed biological and demographic determinants. METHODS:Physical activity was measured with accelerometers (counts per minute) over ≥3 days at baseline and 1 year later in a prospective study of 844 children (41.6% ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2010-0048
更新日期:2010-10-01 00:00:00
abstract:OBJECTIVE:To determine whether it is possible to develop feasible, valid, and reliable multisource feedback data for pediatricians. METHODS:Surveys with 40, 22, 38, and 37 items were developed for assessment of pediatricians by patients, co-workers, medical colleagues, and themselves, respectively, using 5-point scale...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2005-1403
更新日期:2006-03-01 00:00:00
abstract:OBJECTIVE:Many children with human immunodeficiency virus-1 (HIV-1) have chronic problems with growth and nutrition, yet limited information is available to identify infected children at high risk for growth abnormalities. Using data from the prospective, multicenter P2C2 HIV study, we evaluated the relationships betwe...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1542/peds.108.6.1287
更新日期:2001-12-01 00:00:00