Empyema hospitalizations increased in US children despite pneumococcal conjugate vaccine.

Abstract:

OBJECTIVE:To determine if the incidence of empyema among children in the United States has changed since the introduction of the pneumococcal conjugate vaccine in 2000. METHODS:We used the nationally representative Kids' Inpatient Database to estimate the annual total number of hospitalizations of children < or = 18 years of age that were associated with empyema in 1997, 2000,2003, and 2006 [corrected]. Using US Census data, estimated counts were converted into annual incidence rates per 100000 children. Incidence rates were compared between 1997 and later years to determine the impact of pneumococcal conjugate vaccine on hospitalization rates. RESULTS:During 2006, an estimated total of 2898 (95% confidence interval [CI]: 2532-3264) hospitalizations of children

journal_name

Pediatrics

journal_title

Pediatrics

authors

Li ST,Tancredi DJ

doi

10.1542/peds.2009-0184

subject

Has Abstract

pub_date

2010-01-01 00:00:00

pages

26-33

issue

1

eissn

0031-4005

issn

1098-4275

pii

peds.2009-0184

journal_volume

125

pub_type

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