Abstract:
OBJECTIVE:To determine if the incidence of empyema among children in the United States has changed since the introduction of the pneumococcal conjugate vaccine in 2000.
METHODS:We used the nationally representative Kids' Inpatient Database to estimate the annual total number of hospitalizations of children < or = 18 years of age that were associated with empyema in 1997, 2000,2003, and 2006 [corrected]. Using US Census data, estimated counts were converted into annual incidence rates per 100000 children. Incidence rates were compared between 1997 and later years to determine the impact of pneumococcal conjugate vaccine on hospitalization rates.
RESULTS:During 2006, an estimated total of 2898 (95% confidence interval [CI]: 2532-3264) hospitalizations of children journal_name journal_title authors doi subject pub_date pages issue eissn issn pii journal_volume pub_type
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