Persistent pulmonary hypertension in the neonate: development of an animal model.

Abstract:

:Chronic intrauterine hypoxia was induced in third-trimester lamb fetuses by daily embolization of the maternal side of the placenta with nonradioactive microspheres. After delivery at term, the chronically hypoxic fetuses had significantly increased pulmonary artery pressures when compared to nonhypoxic control measurements. This preparation appears to be a satisfactory model for experimental study of persistent pulmonary hypertension in the neonate.

journal_name

Am J Obstet Gynecol

authors

Drummond WH,Bissonnette JM

doi

10.1016/0002-9378(78)90242-9

subject

Has Abstract

pub_date

1978-08-01 00:00:00

pages

761-3

issue

7

eissn

0002-9378

issn

1097-6868

pii

0002-9378(78)90242-9

journal_volume

131

pub_type

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