Abstract:
INTRODUCTION:Oxidative-nitrative stress and poly(ADP-ribose) polymerase activation observed in gestational diabetes may play role in the increased cardiovascular risk in later life. AIM:The present study aimed to examine the influence of the severity of previous gestational diabetes (insulin need) on vascular function three years after delivery. Furthermore, the authors investigated the relation of vascular function with oxidative-nitrative stress and poly(ADP-ribose) polymerase activation. METHOD:Macrovascular function was measured by applanation tonometry; microvascular reactivity was assessed by provocation tests during Laser-Doppler flowmetry in 40 women who had gestational diabetes 3 years before the study. Oxidative-nitrative stress and poly(ADP-ribose) polymerase activity in blood components were determined by colorimetry and immunohistochemistry. RESULTS:Three years after insulin treated gestational diabetes impaired microvascular function and increased oxidative stress was observed compared to mild cases. CONCLUSIONS:The severity of previous gestational diabetes affects microvascular dysfunction that is accompanied by elevated oxidative stress. Nitrative stress and poly(ADP-ribose) polymerase activity correlates with certain vascular factors not related to the severity of the disease.
journal_name
Orv Hetiljournal_title
Orvosi hetilapauthors
Horváth EM,Mágenheim R,Domján BA,Ferencz V,Tänczer T,Szabó E,Benkő R,Szabó C,Tabák Á,Somogyi Adoi
10.1556/650.2015.30307subject
Has Abstractpub_date
2015-11-22 00:00:00pages
1932-6issue
47eissn
0030-6002issn
1788-6120journal_volume
156pub_type
杂志文章相关文献
ORVOSI HETILAP文献大全abstract::The authors report a total of 62 middle and low third rectal cancer cases operated on by total mesorectal excision by the method of Heald. The oncological basis of this procedure is the horizontal regional metastatization of rectal cancer. The total mesorectal excision facilitates, the low anterior resections and pres...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:2000-02-20 00:00:00
abstract::Acute porphyrias are caused by the inherited decreased activity of the enzymes of the heme biosynthesis pathway. Depending on the affected enzyme there are 4 types of them: acute intermittent porphyria, porphyria variegata, coproporphyria and delta-aminolevulinic acid dehydratase deficient porphyria, listed in order o...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:
更新日期:2003-05-11 00:00:00
abstract::Introduction: Autologous hemopoietic stem cell transplantation remains a promising therapy in certain malignant and non-malignant conditions. The procedure, however, will increase the risk of complications, most notably early and late infections. Aim: To analyze the frequency and spectrum of pathogens in early (<+100 ...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/650.2020.31638
更新日期:2020-01-01 00:00:00
abstract:UNLABELLED:Monitoring the pharmacokinetic parameters of different anticancer drugs is necessary because they might have several side effects. AIM:Pharmacokinetic and toxicity evaluation of high-dose methotrexate treatments in children with acute lymphoblastic leukemia. PATIENTS AND METHODS:43 children (28 boys, 15 gi...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/OH.2011.29143
更新日期:2011-10-02 00:00:00
abstract::Heart and blood vessel disease are one of the leading causes of death, so their prevention and therapy are very important. In the present study the effects of magnesium chloride, magnesium orotate and orotic acid were tested. New Zealand rabbits were fed with enriched (2%) cholesterol diet during 112 days: starting wi...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1997-09-07 00:00:00
abstract:INTRODUCTION:In the last few years the rapid development of flexible endoscopies has opened new possibilities in minimal invasive procedures. With the help of these techniques the exposure, the risk of complications and the healing period of the patient might be reduced. One of these procedures is the transgastric inte...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/OH.2007.27889
更新日期:2007-01-28 00:00:00
abstract::The Curling's ulcer is a special form of the stress ulcers which occurs in the stomach and duodenum in 2.0-25%. It's pathogenesis is unknown even though it is clearly related to larger burns poor early treatment and septic complications. Since the institution of routine prophylaxis of H2 receptor antagonists and antac...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1991-02-24 00:00:00
abstract::According to the Semmelweis Plan for Saving Health Care, "the capacity of the national network of intensive care units in Hungary is one but not the only bottleneck of emergency care at present". Author shows on the basis of data reported to the health insurance that not on a single calendar day more than 75% of beds ...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/OH.2011.29137
更新日期:2011-06-12 00:00:00
abstract::Introduction: Subtotal petrosectomy (STP) has been known for decades and it is considered being on the borderline between ear and skull-base surgery. Due to its excessive radicalism and adverse effects on hearing, it has been a forgotten surgical technique until recently. Over the last decade, due to its many benefits...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/650.2020.31691
更新日期:2020-04-01 00:00:00
abstract::The EOS™ X-ray machine, based on a Nobel prize-winning invention in Physics in the field of particle detection, is capable of simultaneously capturing biplanar X-ray images by slot scanning of the whole body in an upright, physiological load-bearing position, using ultra low radiation doses. The simultaneous capture o...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:10.1556/OH.2012.29312
更新日期:2012-02-26 00:00:00
abstract::Rehabilitation of the patients following open heart surgery is strongly influenced by the psychological conditions. Depression plays a crucial negative role in this process. Depression score was measured in patients taking part in the rehabilitation course of our institute last year (1998), 6 weeks after discharge fro...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:2001-10-14 00:00:00
abstract::The biological mechanisms, ecological and observational studies indicate increased morbidity and mortality in vitamin D deficiency, while the controlled, randomized supplementation trials - carried out mostly in vitamin D deficient patients - have shown no or some marginal benefits, mostly in preventing institutionali...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:10.1556/650.2016.30419
更新日期:2016-07-01 00:00:00
abstract::In their earlier work the authors reviewed some methods, which appeared to be suitable for monitoring the redox-status of the human organism and, therefore, may be applied under routine clinical laboratory circumstances. This possibility can lead to a new perspective to set up epidemiological studies in different popu...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:
更新日期:2003-11-23 00:00:00
abstract::The authors have found 244 clavicle fractures during 4131 vaginal delivery (5.91%). Both clavicles of three newborns have fractured. The incidence of fracture had relation to weight of newborns, to weakness of pains and to vacuum extraction. The Apgar score of the newborns with fractured clavicle was not less, than on...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:
更新日期:1991-12-01 00:00:00
abstract::During conception (fusion of maternal and paternal germ cells) a new entity is formed, which has individual structure and functions. From its gene-pool (genome) epigenetic regulation selects those genes which are durably or acutely working, supplying a theoretically lifelong program. However, this program could be cha...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/650.2020.31764
更新日期:2020-06-01 00:00:00
abstract:INTRODUCTION:Metal elements and their excess intake have significant influence on general health. AIM:There is only little information how Far Eastern herbs resemble European's regarding their purity and essential metal element content. The aim of the authors was to determine metal elements in different Chinese and Eu...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/650.2015.30193
更新日期:2015-08-02 00:00:00
abstract::Introduction: Previous data showed bacterial infections among diabetic patients to be more serious and frequent, with higher mortality rates in comparison with non-diabetics. Recent investigations, however, are contradictory. Aim: The goal of our prospective, observational study was to compare patients hospitalized on...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/650.2019.31508
更新日期:2019-10-01 00:00:00
abstract::Since its introduction in 1976, the impact factor is permanently a subject of both criticism and glorification. This paper gives an overview on what actually the reservations and objections attack. A closer look often reveals that the criticisms are not against the specific substantial features of the impact factor. T...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/650.2015.30212
更新日期:2015-06-28 00:00:00
abstract:INTRODUCTION:The price and complication rates of pump models applied in the treatment of intractable ascites are significantly high. The development of a more simple, cheaper technique--using the biologically given venous valves--the saphenoperitoneal shunts became essential. TECHNIQUE AND RESULTS:In authors' departme...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:2004-02-29 00:00:00
abstract:INTRODUCTION:Chronic pelvic pain is a very common disease in women. As a final and life-long solution laparoscopic sacrouterine nerve ablation (LUNA) is generally used in the daily practice. OBJECTIVE:To investigate the effectiveness of LUNA by evaluating their results. PATIENTS AND METHODS:Authors performed sacroute...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:2003-02-02 00:00:00
abstract::Biologic response modifiers. Biologic response modifiers such as IFN-alpha, retinoids and extracorporeal photopheresis have been widely used in the treatment of cutaneous lymphoma. The novel treatment modalities like cytokine therapies, monoclonal antibodies and fusion proteins have been used only in limited number of...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:
更新日期:2005-06-05 00:00:00
abstract::Clinical data on the risk factors, incidence, consequences and current treatment options of venous thromboembolism are reviewed. Current guidelines advise anticoagulant treatment for a few weeks or months in immobilized patients treated in hospital, and after major surgery. The initial treatment is based on heparin, f...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/OH.2011.29140
更新日期:2011-06-19 00:00:00
abstract::Parkinson's disease (PD) is one of the most common neurodegenerative disorders. The morbidity is about 1-2 of 1000 under 65 years, but it increases to 1-2 of 100 in the population over 65 years. PD became the model of degenerative disorders either concerning the etiopathogenesis or the therapeutic possibilities. Recen...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:
更新日期:2000-03-05 00:00:00
abstract::The effect of Vitamin E treatment was studied in experimental hyperlipidaemia. The male Wistar rats got control diet and parallel fat rich diet contained 2% cholesterol, 0.5% cholic acid and 20% sunflower oil added into LATI food during 9 days. The treated hyperlipidemic animals got vitamin E for 9 days in daily 8.56 ...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1993-08-08 00:00:00
abstract::Since the eighties of the last century hormone content was justified in immune cells (lymphocytes, granulocytes, monocytes, macrophages and mast cells), which produce, store and secrete these hormones. Although the amount of these materials in immune cells is relatively small, the mass of the producers (immune cells) ...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:10.1556/OH.2011.29122
更新日期:2011-05-15 00:00:00
abstract::The authors present the case of a 29-year-old female with stab wound to the abdomen. After the initial fluid resuscitation and preliminary radiographic examinations immediate laparotomy was indicated due to hypovolaemic circulatory collapse. Splenectomy and gastric suture were necessary. Following the urgent intervent...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/OH.2007.28044
更新日期:2007-08-12 00:00:00
abstract::The prevalence of hepatitis C virus infection among patients on hemodialysis is about ten times higher than in the normal population. The infection can induce chronic glomerulonephritis, as an extrahepatic manifestation, which can lead to end stage renal disease. However, in the majority of the patients hepatitis C vi...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:10.1556/OH.2007.28007
更新日期:2007-03-18 00:00:00
abstract::The beneficial effect achieved by the treatment of endothelial dysfunction in chronic cardiovascular diseases is already an evidence belonging to the basic treatment of the disease. Given the fact that the vascular system is uniform and consubstantial both physiologically, pathophysiologically and in terms of therapy,...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:10.1556/OH.2008.28237
更新日期:2008-01-20 00:00:00
abstract:INTRODUCTION:Heterotaxy syndrome (Ivemark syndrome, or asplenia-polysplenia syndrome) is a heterogeneous group of disease with disturbed body symmetry and malposition of internal organs. Heterotaxy syndrome is caused by the disturbance of the left/right axis in the early embryonic period. AIM OF THE STUDY:The most fre...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:
更新日期:2002-02-10 00:00:00
abstract::The author discusses about non-usual application of Cu containing intrauterine contraceptive device. An oophoropexy was performed on a 19 years old female suffering from Hodgkin disease. A Cu intrauterine contraceptive device was introduced into the uterine cavity to help in localising the radiological treatment. The ...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1989-02-26 00:00:00