Abstract:
:Heart and blood vessel disease are one of the leading causes of death, so their prevention and therapy are very important. In the present study the effects of magnesium chloride, magnesium orotate and orotic acid were tested. New Zealand rabbits were fed with enriched (2%) cholesterol diet during 112 days: starting with day 56 all rabbits were treated with MgCl2, Mg-orotate or orotic acid (orally). Aortas, coronaries, renal and femoral arteries were removed and evaluated by morphological and morphometric methods. Atherosclerotic alterations in each vessel could be influenced moderately by Mg-chloride, quite well by orotic acid and excellently by Mg-orotate. From these results one can conclude that orotic acid and Mg-orotate have a beneficial effect in the prevention and therapy of heart and vessels diseases.
journal_name
Orv Hetiljournal_title
Orvosi hetilapauthors
Jellinek H,Takács Esubject
Has Abstractpub_date
1997-09-07 00:00:00pages
2276-80issue
36 Suppl 2eissn
0030-6002issn
1788-6120journal_volume
138pub_type
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