[Morphological aspects of the effect of magnesium orotate therapy on changes in the vascular walls induced by cholesterol-rich diet].

Abstract:

:Heart and blood vessel disease are one of the leading causes of death, so their prevention and therapy are very important. In the present study the effects of magnesium chloride, magnesium orotate and orotic acid were tested. New Zealand rabbits were fed with enriched (2%) cholesterol diet during 112 days: starting with day 56 all rabbits were treated with MgCl2, Mg-orotate or orotic acid (orally). Aortas, coronaries, renal and femoral arteries were removed and evaluated by morphological and morphometric methods. Atherosclerotic alterations in each vessel could be influenced moderately by Mg-chloride, quite well by orotic acid and excellently by Mg-orotate. From these results one can conclude that orotic acid and Mg-orotate have a beneficial effect in the prevention and therapy of heart and vessels diseases.

journal_name

Orv Hetil

journal_title

Orvosi hetilap

authors

Jellinek H,Takács E

subject

Has Abstract

pub_date

1997-09-07 00:00:00

pages

2276-80

issue

36 Suppl 2

eissn

0030-6002

issn

1788-6120

journal_volume

138

pub_type

杂志文章
  • [Management of injuries of the artificial esophagus].

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    doi:

    authors: Oláh T,Horváth Ors P

    更新日期:1990-05-27 00:00:00

  • [Idiopathic hypercalciuria in childhood].

    abstract::This review describes the supposed mechanisms leading to idiopathic hypercalciuria (IHU) in childhood, further the diagnostic criteria and the proposed treatment modalities are discussed. IHU is not only one of the main causes of renal stone disease in children but it's also at the origin of the postglomerular haematu...

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    pub_type: 杂志文章,评审

    doi:

    authors: Reusz G

    更新日期:1998-12-06 00:00:00

  • [Comparison of the effect of multidrug resistance modifiers on prostate cancer, mouse lymphoma and colon cancer cells].

    abstract:INTRODUCTION:The reason for unsuccessful tumor chemotherapy is related to multidrug resistance. An important factor is the overexpression of efflux pumps, such as P-glycoprotein. AIM:Amino- and amide-substituted steroid compounds and phenothiazine derivatives were investigated in tumor models in vitro. METHOD:The inh...

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    doi:10.1556/650.2016.30536

    authors: Csonka Á

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  • [The clinical relevance of experimental acute pancreatitis models].

    abstract::The clinical diagnostics and therapeutic standards applied in the routine management of human acute pancreatitis are based on the results of animal experiments and human studies performed in the past several decades. During this time period, a number of experimental acute pancreatitis models have been developed, which...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:10.1556/OH.2008.28464

    authors: Takács T,Szabolcs A,Biczó G,Hegyi P,Rakonczay Z

    更新日期:2008-10-19 00:00:00

  • [Dissolving anxiety as an essential ingredient for any therapy].

    abstract::Anxiety frequently develops in human life and it is usually useful for the organism. Anxiety helps accomodation to the social environment, however, it may be harmful when it is intensive and long-lasting. It can also cause psychosomatic diseases. Anxiety may present itself as mild or moderate stress, psychosomatic dis...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:10.1556/OH.2014.29925

    authors: Radics J

    更新日期:2014-06-01 00:00:00

  • [Transgastric gastro-jejunal anastomosis with flexible endoscope on a biosynthetic model].

    abstract:INTRODUCTION:In the last few years the rapid development of flexible endoscopies has opened new possibilities in minimal invasive procedures. With the help of these techniques the exposure, the risk of complications and the healing period of the patient might be reduced. One of these procedures is the transgastric inte...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:10.1556/OH.2007.27889

    authors: Lukovich P,Kádár B,Jónás A,Sadatakhavi M,Váradi G,Tari K,Kupcsulik P

    更新日期:2007-01-28 00:00:00

  • [Oily contrast medium used for chemoembolization in the palliative treatment of extensive inoperable primary hepatocellular carcinomas].

    abstract::Transcatheter arterial oily chemoembolization using cytostatics mixed with lymphographic contrast agent with or without Gelfoam embolization seems currently to be the most suitable treatment for unresectable hepatocellular carcinomas (HCC). 5 patients with inoperable, biopsy proven huge HCC (average size 404 cm2) were...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:

    authors: Kónya A,Vigváry Z

    更新日期:1994-01-30 00:00:00

  • [Prediction of the disease course in inflammatory bowel diseases].

    abstract::Clinical presentation at diagnosis and disease course of both Crohn's disease (CD) and ulcerative colitis (UC) are heterogeneous and variable over time. During follow up, intestinal strictures or perforation may eventually develop at most patients with CD, and significant number of patients will undergo surgery. Much ...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:10.1556/OH.2010.28813

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    更新日期:2010-02-21 00:00:00

  • [Acute pancreatitis: recent advances in understanding its pathophysiology].

    abstract::This article reviews the recent changes in the understanding of acute pancreatitis pathophysiology emphasizing results deriving from the more detailed comprehension of the local and systemic aspects of the inflammatory process. The authors briefly discuss those theories that have been influencing the basic philosophie...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:

    authors: Telek G,Fehér J,Jakab F,Claude R

    更新日期:2000-02-06 00:00:00

  • [Primary liver cancer following prolonged use of contraceptive drugs].

    abstract::The authors have observed cancer of the liver without cirrhosis, in a woman aged 32. The disease manifested itself immediately after childbirth and provoked death 3 months after the delivery. Before her pregnancy, the patient had been taking Infecundin for 7 years. The pregnancy went to term without any difficulty....

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:

    authors: Balázs M,Gergely R,Winkler G

    更新日期:1977-02-06 00:00:00

  • [Frequency of hyperhomocysteinemia in hemodialysis patients with folic acid supplementation].

    abstract:BACKGROUND:It is known that hyperhomocystinemia is an independent risk factor for development of atherosclerosis. In end stage renal disease the frequency of hyperhomocystinemia is much greater than in normal populations. AIM:In this study homocystein (Hcy), folic acid and vitamin B12 concentrations were determined in...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:

    authors: Kárpáti I,Balla J,Szóke G,Bereczky Z,Páll D,Ben T,Toma K,Katona E,Mohácsi A,Paragh G,Varga Z,Kakuk G,Muszbek L

    更新日期:2002-07-07 00:00:00

  • [Improving of muscle mass and force in rehabilitation of heart-lung patients. Aerobic interval training, resistance-exercises, excentric exercises, vibration].

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    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:

    authors: Apor P,Tihanyi J,Borka P

    更新日期:2005-09-18 00:00:00

  • [Postural tachycardia syndrome].

    abstract::Erect posture could be a source of diverse chronic symptoms usually referred as orthostasis intolerance. Increasing number of patients suffering from orthostatic syndromes is recognized. Characterization and distinction of these orthostatic syndromes are based on the clinical presentation; including the typical histor...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:

    authors: Makai A,Tahin T,Simor T,Csanádi Z,Rudas L

    更新日期:2005-03-13 00:00:00

  • [Influence of diabetes mellitus on cerebral ischemia and reperfusion injury].

    abstract::Cerebral ischemia, caused by disturbance of the blood supply to the brain, is a major cause of death in our days. Diabetes mellitus exacerbates neuronal death induced by an ischemic insult. It is important to characterize the underlying mechanism of the cell damage in order to design therapeutic agents. The purpose of...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:

    authors: Murányi M,Lacza Z

    更新日期:2006-10-01 00:00:00

  • [Myopathy associated with respiratory insufficiency: diagnostic difficulties in adult-onset Pompe disease].

    abstract:INTRODUCTION:Adult-onset acid maltase deficiency myopathy is a rare lysosomal storage disease with an autosomal recessive pattern of inheritance. The disease can be manifested with respiratory insufficiency and fatigue. METHODS:A case of a 45-year-old male patient is presented, and difficulty in diagnosis is discussed...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:

    authors: Merkli H,Pál E,Nagy F,Horváth R,Várdi VK,Komoly S,Illés Z

    更新日期:2006-07-30 00:00:00

  • [Changes in the evaluation and treatment of benign prostatic hypertrophy].

    abstract::The benign prostatic hyperplasia (BPH) is regarded as a widespread disease "potentially prevalent among the masses" owing to the increase of men's age. Morbidity rises from the age of 50, it runs up to 80-85% and causes symptoms in 40-60% that must be treated. Research and technical development have resulted important...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:

    authors: Wabrosch G,Vanik M

    更新日期:1993-10-31 00:00:00

  • [Polymyositis-dermatomyositis recognized during the follow-up of a patient with type 2 diabetes].

    abstract::Polymyositis-dermatomyositis is a rare systemic autoimmune disease which belongs to the class of idiopathic inflammatory myopathies. The disease exhibits high inter-individual variability, but chronic myositis is a common feature. As different manifestations often appear in atypical forms, establishing the precise dia...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:10.1556/OH.2012.29300

    authors: Samer F,Csóka M,Dankó K

    更新日期:2012-03-25 00:00:00

  • [Pulsatile gonadotropin releasing hormone treatment following previous ovarian hyperstimulation].

    abstract::Physiological follicular maturation was achieved by pulsatile gonadotrophin releasing hormone treatment in ovarian hyperstimulatory cases induced previously by other ovulation induction methods (clomiphene, clomiphene + hCG, clomiphene + hMG + hCG). The follicular development was detected by vaginal ultrasound examina...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:

    authors: Koloszár S,Bártfai G

    更新日期:1993-07-11 00:00:00

  • [Management of Oddi sphincter dyskinesis. Results of drug therapy and sphincterotomy].

    abstract:UNLABELLED:In a retrospective evaluation, the outcome of the long term treatment of the sphincter of Oddi dyskinesia (OD, type III. dysfunction) has been analysed. PATIENTS AND METHOD:Therapeutic results of 64 cholecystectomised patients with OD were evaluated by means of regular follow-up and questionnaire filled in ...

    journal_title:Orvosi hetilap

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Döbrönte Z,Simon L,Patai A

    更新日期:1995-10-01 00:00:00

  • [The severity of gestational diabetes mellitus affects microvascular dysfunction measured three years after pregnancy that may be related to increased oxidative stress].

    abstract:INTRODUCTION:Oxidative-nitrative stress and poly(ADP-ribose) polymerase activation observed in gestational diabetes may play role in the increased cardiovascular risk in later life. AIM:The present study aimed to examine the influence of the severity of previous gestational diabetes (insulin need) on vascular function...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:10.1556/650.2015.30307

    authors: Horváth EM,Mágenheim R,Domján BA,Ferencz V,Tänczer T,Szabó E,Benkő R,Szabó C,Tabák Á,Somogyi A

    更新日期:2015-11-22 00:00:00

  • Standardized measurement in uterine ultrasonography

    abstract::Összefoglaló. Bevezetés: Jelenleg a méh méretének pontos megítélése meglehetősen szubjektív, az azt leíró ultrahangleletek igen nagy eltérést mutatnak. Számos klinikai szituációban azonban nagyon fontos az eltérések méretének, elhelyezkedésének, meghatározott anatómiai pontokhoz való viszonyának pontos leírása. Célkit...

    journal_title:Orvosi hetilap

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    doi:10.1556/650.2020.31929

    authors: Kovács KS,Kovács AR,Harangi B,Lampé R,Török P

    更新日期:2020-11-29 00:00:00

  • [Risk-based prediabetes screening in a rural general practice - oral glucose tolerance test or glycated hemoglobin?]

    abstract::Introduction and aim: The aim of this study was to implement a two-stage diabetes screening programme in a severely disadvantaged municipality. In the first stage, diabetes risk assessment was carried out in the 18 to 75 age group, followed by screening of the high risk population for potential carbohydrate metabolism...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:10.1556/650.2019.31573

    authors: Galvács H,Szabó J,Balogh Z

    更新日期:2019-12-01 00:00:00

  • [Pulmonary infections following solid organ transplantation].

    abstract::Solid organ transplantation is the standard of care for selected patients with severe vital organ dysfunction. The need for immunosuppression to prevent organ rejection is a common characteristic of recipients. Immunosuppression increases the risk of infections, especially with low virulence opportunistic pathogens. I...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:10.1556/OH.2012.29395

    authors: Müller V,Kováts Z,Horváth G

    更新日期:2012-06-10 00:00:00

  • [Genetic evaluation of mental retardation].

    abstract::About 3% of the population is mentally retarded. Due to the progress in medical genetics, congenital origin of disability may be explored in an increasing number of affected children, however, the etiology can still not be determined in a large proportion of the cases, although this would be indispensable for a ration...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:

    authors: Méhes K,Kosztolányi G

    更新日期:1998-02-15 00:00:00

  • [First decade of post-genomic era. Hopes, disappointments, new answers].

    abstract::The first decade after the announcement of the draft sequence of human genome has brought spectacular advances in basic science, however, the fact that human health did not benefit that much caused disappointment, as well. In order to explore the causes of the absence of revolution in medicine, beside the extension of...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:10.1556/OH.2010.29014

    authors: Kosztolányi G

    更新日期:2010-12-19 00:00:00

  • [Antioxidant effect of vitamin E in experimental hyperlipidemia].

    abstract::The effect of Vitamin E treatment was studied in experimental hyperlipidaemia. The male Wistar rats got control diet and parallel fat rich diet contained 2% cholesterol, 0.5% cholic acid and 20% sunflower oil added into LATI food during 9 days. The treated hyperlipidemic animals got vitamin E for 9 days in daily 8.56 ...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:

    authors: Horváth EM,Blázovics A,Kemény T,Vásárhelyi B,Weinbrenner Z,Fehér J

    更新日期:1993-08-08 00:00:00

  • [Experience with gestodene-containing hormonal contraceptive].

    abstract::An oral contraceptive containing gestodene (Minulet) was examined in collaborating with the Richter-Wyeth Pharmaceutical Factory. The authors present their experiences of monitoring of 591 cycles of a hundred women between 18 and 35 years of age. There were no pregnancy and severe side effects during that period. Irre...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:

    authors: Szabó L,Nagy K,Godó G

    更新日期:1998-03-01 00:00:00

  • [Cardiovascular disease-related serum lipid parameters in a Hungarian subpopulation].

    abstract::The blood samples of 229 volunteers (100 men, aged 35-59 y and 129 women, aged 35-54 y) were randomly selected and analysed for serum lipids (triglyceride, total, HDL- and LDL-cholesterol), apolipoproteins (apolipoprotein A1, A2 and B) and Lp(a). The mean serum level of triglyceride was in the high risk category in ma...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:

    authors: Szépvölgyi J,Kravják BE,Bíró L,Nagy K,Bíró G,Antal M

    更新日期:1997-08-10 00:00:00

  • [Neurovesical dysfunction in children with anorectal malformations].

    abstract::Chronic renal failure remain the most significant cause of morbidity and mortality in patients with anorectal malformation. The urological anomalies associated with anorectal malformations are not only anatomical, but also functional, the latter being related to congenital neurovesical dysfunction. The neurovesical dy...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:

    authors: Bán G,Németh P,Túri S

    更新日期:2006-08-27 00:00:00

  • [Gastric and duodenal intramural hematoma: report of two cases].

    abstract::Two cases of intramural hematoma arising in the duodenum and the stomach are reported. Both patients were male, aged 40 and 58 years, and suffered from chronic pancreatitis. Hematoma of the duodenal wall may have resulted from the acute exacerbation of the chronic pancreatitis in the first patient. As to the second ca...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:

    authors: Dibuz M,Szabó T,Monoki E,Nagymélykuti L,Illyés M,Varga E,Csípö L

    更新日期:1998-12-06 00:00:00