[Current pharmacotherapy of Parkinson's disease].

Abstract:

:Parkinson's disease (PD) is one of the most common neurodegenerative disorders. The morbidity is about 1-2 of 1000 under 65 years, but it increases to 1-2 of 100 in the population over 65 years. PD became the model of degenerative disorders either concerning the etiopathogenesis or the therapeutic possibilities. Recently the therapy is focused mostly on pharmaceutics, although the treatment of PD is complex. The new drugs improve the quality of life, and there is some evidence that some of them may slow down the progression of the disease. These drugs may provide a neuroprotective therapy, and so a better life expectancy.

journal_name

Orv Hetil

journal_title

Orvosi hetilap

authors

Takáts A

subject

Has Abstract

pub_date

2000-03-05 00:00:00

pages

483-8

issue

10

eissn

0030-6002

issn

1788-6120

journal_volume

141

pub_type

杂志文章,评审
  • [The hypertensive role of corticosteroids in the light of adenoma of the adrenal cortex].

    abstract::Corticosteroid-dependent hypertension can be cured by surgical removal of steroid-producing adrenocortical adenomas or, in case of other etiopathologic factors, specific drug therapy may be introduced for preventing irreversible complications of the hypertension process. In most cases, corticosteroid-dependent hyperte...

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    doi:

    authors: Gláz E

    更新日期:1989-05-28 00:00:00

  • [Changes in the innervation of the taste buds in diabetic rats].

    abstract:INTRODUCTION:Abnormal sensations such as pain and impairment of taste are symptoms of approximately 10% of patients having diabetes mellitus. AIM:The aim of the study was to investigate and quantify the different neuropeptide containing nerve fibres in the vallate papilla of the diabetic rat. METHODS:Immunohistochemi...

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    doi:10.1556/OH.2013.29570

    authors: Hevér H,Altdorfer K,Zelles T,Batbayar B,Fehér E

    更新日期:2013-03-24 00:00:00

  • [Epidemiology, risk factors and molecular pathogenesis of primary liver cancer].

    abstract::Primary liver cancer is the fifth most common cancer worldwide. Hepatocellular carcinoma accounts for 85-90% of primary liver cancers. Distribution of hepatocellular carcinoma shows variations among geographic regions and ethnic groups. Males have higher liver cancer rates than females. Hepatocellular carcinoma occurs...

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    doi:10.1556/OH.2008.28313

    authors: Hagymási K,Tulassay Z

    更新日期:2008-03-23 00:00:00

  • [Clinico-pathological and orthopedic-surgical aspects of essential osteolysis (Gorham disease)].

    abstract::Authors present two cases. One of their patient was followed for 30 years. They discuss the pathological characters and diagnostic difficulties of the disease. They have observed that with radical operations of--according to necessity--serial surgical interventions the outcome of patients can be properly controlled ag...

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    pub_type: 杂志文章

    doi:

    authors: Riskó T,Bély M,Lakatos J

    更新日期:1993-04-04 00:00:00

  • [Experience with only preoperative radiotherapy of non-metastatic rectal tumours].

    abstract:INTRODUCTION:It is an accepted fact that the local recurrence rate can be decreased up to 50% for the metastatic rectum tumours irradiated only preoperatively. MATERIALS AND METHODS:181 patients having rectum tumour were irradiated preoperatively with 36 or 40 Gy between 1990 and 2001. The classification was made acco...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:10.1556/OH.2007.28045

    authors: Patyánik M,Solymosi N,Bégányi N,Sinkó D,Mayer A

    更新日期:2007-09-02 00:00:00

  • [Antihypertensive drug trials also reveal renoprotective effects].

    abstract::The author analyzes the applicability of the renin-angiotensin system blocking drugs in patients with chronic kidney disease emphasizing their renoprotective (blood pressure and albuminuria lowering) and cardiovascular risk decreasing effects. As opposed to a previously-published statement, the author believes that th...

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    pub_type: 杂志文章

    doi:10.1556/OH.2013.29609

    authors: Kiss I

    更新日期:2013-05-12 00:00:00

  • [Pharmacokinetic analysis of high-dose methotrexate treatments in children with hematologic malignancies].

    abstract:UNLABELLED:Monitoring the pharmacokinetic parameters of different anticancer drugs is necessary because they might have several side effects. AIM:Pharmacokinetic and toxicity evaluation of high-dose methotrexate treatments in children with acute lymphoblastic leukemia. PATIENTS AND METHODS:43 children (28 boys, 15 gi...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:10.1556/OH.2011.29143

    authors: Csordás K,Eipel O,Hegyi M,Csóka M,Pap E,Kovács G

    更新日期:2011-10-02 00:00:00

  • [Nicolau syndrome after ketazon injection].

    abstract::Nicolau syndrome is a rare complication, which occurs after intramuscular injections of various drugs, particularly antirheumatic drugs. During one year, the authors observed this syndrome in three patients, who had received intramuscular injections of Ketazon. The aetiology of the syndrome is not yet known, but it is...

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    pub_type: 杂志文章

    doi:

    authors: Varga L,Asztalos L

    更新日期:1990-05-27 00:00:00

  • [Determination of serum semicarbazide-sensitive amine oxidase activity in diabetic retinopathy in type-2 diabetes].

    abstract:INTRODUCTION:Recent data suggest that the copper-containing semicarbazide-sensitive amine oxidase enzyme (SSAO) may play a role in vascular endothelial damage through conversion of certain endogenous monoamines, like methylamine into cytotoxic aldehydes, hydrogen peroxide and ammonia. SSAO is present in various human t...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:

    authors: Dura E,Mészáros Z,Salacz G,Magyar K,Romics L,Karádi I

    更新日期:2002-11-24 00:00:00

  • [Neurovesical dysfunction in children with anorectal malformations].

    abstract::Chronic renal failure remain the most significant cause of morbidity and mortality in patients with anorectal malformation. The urological anomalies associated with anorectal malformations are not only anatomical, but also functional, the latter being related to congenital neurovesical dysfunction. The neurovesical dy...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:

    authors: Bán G,Németh P,Túri S

    更新日期:2006-08-27 00:00:00

  • [Arrhytmogenic right ventricle--prognostic significance of exercise test].

    abstract:UNLABELLED:The authors summarize the present knowledge on arrhythmogenic right ventricular cardiomyopathy/dysplasia. Limited data are available about natural history of asymptomatic patients with arrhythmogenic right ventricle cardiomyopathy/dysplasia, who have a ventricular tachycardia during exercise test. A 25-year ...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:10.1556/OH.2010.28995

    authors: Jánosi A,Vágó H,Hubay M

    更新日期:2010-12-26 00:00:00

  • [Cardiovascular prevention with peripheral artery disease].

    abstract::Peripheral artery disease is a global disease. When present, the occurrence of cardiovascular events and death rises. Patients suffering from peripheral artery disease belong to the high CV risk category. Based on the prevention recommendations when PAD is present, treatments with and without medicine are equally nece...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:10.1556/OH.2007.28128

    authors: Vértes A

    更新日期:2007-07-15 00:00:00

  • [Characteristics of cellular infiltration in rejected renal grafts].

    abstract::The composition of the cellular infiltrate in 42 needle and wedge biopsies of transplanted kidneys was investigated immunohistochemically. The various inflammatory cell populations were examined in different rejection types and cyclosporin-A nephrotoxicity (CsAN) as well as in different locations in the graft (perivas...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:

    authors: Nádasdy T,Krenács T,Kalmár-Nagy K,Csajbók E,Boda K,Ormos J

    更新日期:1990-01-28 00:00:00

  • [Dietary survey in Hungary, 2003-2004].

    abstract::The third Hungarian national dietary survey was conducted in 2003-2004. This publication describes the first part of the energy and nutrient intake findings in a sample consisting of a population of 1179 persons over 19 years of age (energy and macro nutrients). Energy and nutrient intake values were calculated based ...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:

    authors: Rodler I,Bíró L,Greiner E,Zajkás G,Szórád I,Varga A,Domonkos A,Agoston H,Balázs A,Mozsáry E,Vitrai J,Hermann D,Boros J,Németh R,Kéki Z

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  • [Clinical experience with surgical management of atrial myxoma].

    abstract::Clinical data (symptoms, diagnostic tools, surgical and histological findings, postoperative course and present status) of 26 patients with cardiac myxomas were reviewed. All myxomas were of left atrial localization. The diagnosis was confirmed by cardiac catheterization and angiography (until late seventies) and echo...

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    pub_type: 杂志文章

    doi:

    authors: Simonfalvi I,Tomcsányi I,Somogyi A,Nagy E,Busman C,Tarr F,Lónyai T

    更新日期:1999-05-16 00:00:00

  • [Anesthesiologic and intensive care requirements in liver transplantation].

    abstract::The complex anaesthesia and intensive care of liver transplantation require special instruments beside expert's knowledge. We monitorize the haemodynamics invasively during the operation and immediately afterward. In the later period of intensive care we prefer the noninvasive haemodynamic monitoring techniques. The t...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:

    authors: Bobek I,Járay J,Perner F

    更新日期:1996-10-20 00:00:00

  • [Initial experiences with 123-Iodine-IBZM neuroreceptor scintigraphy in extrapyramidal disorders].

    abstract::The receptor scintigraphy of the dopaminergic system of the brain is of interest in the evaluation of movement disorders. The 123I-IBZM is a radiopharmaceutical with affinity predominantly to postsynaptic D2 receptors. The aim of this study was to evaluate the role of IBZM SPECT investigations in the differentiation o...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:

    authors: Pávics L,Dibó G,Ambrus E,Séra T,Vécsei L,Csernay L

    更新日期:2000-05-14 00:00:00

  • [Changes in the left ventricular diastolic function in acute myocardial infarction].

    abstract::Changes of left ventricular systolic function in acute myocardial infarction are well known. However, diastolic function may also have a role for patients' symptoms and prognosis. The purpose of this study was to evaluate changes of diastolic function non-invazively and to delineate the relation between systolic and d...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:

    authors: Temesvári A,Kaare S

    更新日期:1996-02-25 00:00:00

  • [Minimally invasive interventions in the treatment of pancreatic diseases].

    abstract::We have used minimal invasive therapy in the treatment of pancreatic diseases for a long time. CT and/or ultrasound guided techniques have been used for the treatment of pancreatic pseudocysts for more than 20 years. The development of technology has also made an opportunity for the extensive use of laparoscopic surge...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:10.1556/OH.2008.28484

    authors: Winternitz T

    更新日期:2008-11-30 00:00:00

  • [Immunohistologic changes of the intestinal mucosa in chronic inflammatory bowel diseases].

    abstract::In the pathogenesis of inflammatory bowel disease abnormally increased immune reactions in the intestinal mucosa play a basic role. The revealing of these reactions was facilitated by the rapidly spreading immunohistological methods in last decades. This review discusses in detail the characteristic distribution of ly...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:

    authors: Arató A

    更新日期:2002-12-08 00:00:00

  • Extracorporeal irradiation: biological reconstruction following tumor resection with a large bone defect

    abstract::Összefoglaló. A malignus csonttumorok sebészi ellátása során kialakuló szegmentális csontdefektusok pótlása fontos szempont a végtagmegtartó sebészetben. Felnőttkorban a megoldás rendszerint tumorprotézis beültetése, 10 évesnél fiatalabb gyermekeknél azonban ez nehezen alkalmazható módszer a kis csontméret és az igen ...

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    doi:10.1556/650.2020.31767

    authors: Perlaky T,Kiss J,Szalay K,Maysam MA,Ágoston P,Szendrői M

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  • [Corneal transplantation in Hungary. Data of the National Keratoplasty Registry 1992-1996].

    abstract::Upon the request of the National Transplantation Committee a nationwide keratoplasty register is functioning at the Department of Ophtalmology, University Medical School of Debrecen. Since then at the end of each year we collected data from the University Departments and Hospitals performing corneal transplantation co...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:

    authors: Berta A,Facskó A,Kelenhegyi C,Módis L

    更新日期:1997-06-29 00:00:00

  • [Experience with the surgical management of rupture of the capsule and ligament of the acromioclavicular joint].

    abstract::Evaluating the surgical results obtained with 74 cases of acromioclavicular dislocation the authors review the problems of diagnostics and surgical treatment of the injury. It is pointed out that the restoration of the functional anatomical condition--and simultaneously the reduction of the number of posttraumatic com...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:

    authors: Sánta S,Varga Z,Antal S

    更新日期:1989-07-16 00:00:00

  • [Esophageal dilatation using the Savary-Gilliard sound set].

    abstract::Authors present a method of esophageal dilatation and report their experiences. The place of esophageal dilatation among other therapeutic approaches of esophageal stricture is discussed. The advantage of Savary-Gilliard bougies and guide wire and its applications are presented. During one and a half year 218 esophage...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:

    authors: Szendrényi V,Lázár G,Oláh T,Horváth Ors P

    更新日期:1992-11-15 00:00:00

  • [First detection of human metapneumovirus in a child with respiratory syndrome in Hungary].

    abstract:INTRODUCTION:Human metapneumovirus was identified in 2001 as a respiratory-tract pathogen that has been classified as a new genera in family Paramyxoviridae. AIMS:Molecular detection of human metapneumovirus in Hungary. MATERIALS AND METHODS:Human metapneumovirus was identified in nasopharyngeal aspirate amplificatio...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:

    authors: Reuter G,Szabó H,Székely G,Gyurkovits K,György S

    更新日期:2006-12-03 00:00:00

  • [Role of blood glucose in prediction of cardiovascular risk].

    abstract::Increased cardiovascular risk in diabetes mellitus has been well-documented. In contrast, it is not widely known, that the relation between degree of hyperglycemia and mortality of diabetics or nondiabetics with acute coronary syndromes (ACS) shows a positive correlation. Insulin treatment significantly improves survi...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:

    authors: Simon K,Szépvölgyi A,Dobó E,Szabó A

    更新日期:2006-01-22 00:00:00

  • [Helicobacter pylori in benign gastroduodenal diseases].

    abstract::(A light- and electronmicroscopic study). We have examined the occurrence of Helicobacter pylori (HP) in 2937 gastric antral biopsy specimens from 979 patients with upper gastrointestinal symptoms. The incidence of HP proved to be 50.5%. The endoscopic diagnoses were: gastritis (62 cases), gastric erosion (425), gastr...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:

    authors: Joós A,Németh A,Zsolnay G,Kövári E,Papp J

    更新日期:1995-04-02 00:00:00

  • [Long-term follow-up after tympanostomy tube insertion in children with serous otitis media].

    abstract:INTRODUCTION:The authors report about the efficacy of inserted tympanostomy tube in children with serous otitis media. AIM:The aim of the authors was to assess the status of eardrum, the function of Eustachian tube and hearing level 10 years after the use of tympanostomy tube. METHOD:Patients filled out a questionnai...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:10.1556/650.2015.30291

    authors: Fekete-Szabó G,Kiss F,Rovó L

    更新日期:2015-11-15 00:00:00

  • [Stem cell therapy in cardiovascular diseases].

    abstract::Myocardial infarction is the leading cause of congestive heart failure in the industrialized world. Current treatments fail to address the underlying scarring and cell loss, which are the causes of ischaemic heart failure. Recent interest has focused on stem cells, which are undifferentiated and pluripotent cells that...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:

    authors: Vértesaljai M,Piróth Z,Fontos G,Andréka G,Font G,Szánthó G,Réti M,Masszi T,Andréka P

    更新日期:2005-11-20 00:00:00

  • [The role of adhesion molecules in atherosclerosis and diabetes mellitus].

    abstract::Adhesion of circulating cells to the vascular endothelium is an early step in the development of atherosclerosis. Diabetic patients have a 2-4 fold increased risk for the development of atherosclerosis. Expression of adhesion molecules is increased in diabetes. These molecules may contribute to accelerated atheroscler...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:

    authors: Gaál Z,Ruzicska E,Valenta B,Somogyi A

    更新日期:2000-11-12 00:00:00