Abstract:
:Biologic response modifiers. Biologic response modifiers such as IFN-alpha, retinoids and extracorporeal photopheresis have been widely used in the treatment of cutaneous lymphoma. The novel treatment modalities like cytokine therapies, monoclonal antibodies and fusion proteins have been used only in limited number of patients with therapy refractory diseases, in advanced stages. The treatment responses of novel cytokine therapies, IFN-gamma, IL-2 and IL-12, are encouraging. Anti- CD52 monoclonal antibody treatment resulted in complete or partial remission in both mycosis fungoides and Sezary syndrome, however serious infectious complications hinder the wide-range usage. DAB 389IL-2 fusion protein-consisting of the toxic portion of diphtheria toxin and the IL-2 sequence has been used for advanced stages of CTCL. RXR retinoids are effective treatment for both early and advanced stages, in form of monotherapy or in combination treatment.
journal_name
Orv Hetiljournal_title
Orvosi hetilapauthors
Marschalkó Msubject
Has Abstractpub_date
2005-06-05 00:00:00pages
1251-5issue
23eissn
0030-6002issn
1788-6120journal_volume
146pub_type
杂志文章,评审相关文献
ORVOSI HETILAP文献大全abstract:INTRODUCTION:Extension of electrocardiographic monitoring via loop recorder implantation may increase the diagnostic yield of syncope work-up. AIM:In this retrospective observational study, the authors wanted to evaluate the diagnostic performance of implantable loop recorder in the everyday clinical practice. METHOD...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/OH.2015.30124
更新日期:2015-04-01 00:00:00
abstract::Therapeutic exercises are the broadest and most challenging parts of physiotherapy which have developed significantly during the last few decades. Their implication is necessary for the treatment of impairments and activities affecting especially the musculoskeletal system. In addition, therapeutic exercises, includin...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:10.1556/OH.2013.29761
更新日期:2013-12-01 00:00:00
abstract::Follicular lymphoma is one of the most common indolent nodal non-Hodgkin's lymphomas. The follicular lymphoma should be differentiated from other nodal non-germinal centre derived lymphomas. Since bcl-2 gene translocation can be detected in 80-90% of the cases, it could be used for the confirmation of the diagnosis, m...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:
更新日期:2003-11-16 00:00:00
abstract::The clinical diagnostics and therapeutic standards applied in the routine management of human acute pancreatitis are based on the results of animal experiments and human studies performed in the past several decades. During this time period, a number of experimental acute pancreatitis models have been developed, which...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:10.1556/OH.2008.28464
更新日期:2008-10-19 00:00:00
abstract::Type 2 diabetes is a progressive disease and its consequence is the gradual decrease of endogenous insulin secretion to a very low level. Beyond this point, without insulin it is not possible to achieve proper metabolic compensation. The authors are trying to explain why the insulin therapy is often delayed in type 2 ...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/650.2019.31269
更新日期:2019-01-01 00:00:00
abstract::Introduction: Recently published unfavourable results of endoscopic radical surgery for early-stage cervical cancer compared to open surgery raises the need for auditing treatment results of endoscopic staging surgery for endometrial cancer. Aim: Comparison of progression-free and overall survival (PFS and OS) between...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/650.2020.31675
更新日期:2020-03-01 00:00:00
abstract::Clinical data (symptoms, diagnostic tools, surgical and histological findings, postoperative course and present status) of 26 patients with cardiac myxomas were reviewed. All myxomas were of left atrial localization. The diagnosis was confirmed by cardiac catheterization and angiography (until late seventies) and echo...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1999-05-16 00:00:00
abstract::Since the eighties of the last century hormone content was justified in immune cells (lymphocytes, granulocytes, monocytes, macrophages and mast cells), which produce, store and secrete these hormones. Although the amount of these materials in immune cells is relatively small, the mass of the producers (immune cells) ...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:10.1556/OH.2011.29122
更新日期:2011-05-15 00:00:00
abstract::In the past few years, ultrasonography has become the most widespread and easily available diagnostic procedure in gynecological practice. the high-frequency transvaginal probe provides a detailed visualization of the reproductive organs and the urinary bladder. however, in spite of this generally applied examination ...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:2005-02-27 00:00:00
abstract::The Hungarian primary care quality indicator system has been introduced in 2009, and has been continuously developed since then. The system offers extra financing for family physicians who are achieving the expected levels of indicators. There are currently 16 indicators for adult and mixed practices and 8 indicators ...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:10.1556/650.2016.30378
更新日期:2016-02-28 00:00:00
abstract::According to epidemiological studies, the prevalence of pituitary adenomas is 16.5% and the majority of them are "incidentalomas". The symptoms of pituitary disorders are often non-specific; disturbances of pituitary function, compression symptoms, hypophysis apoplexy or accidental findings may help the diagnosis. The...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:10.1556/OH.2009.28584
更新日期:2009-09-27 00:00:00
abstract::Clinical examination of potential tubal disease is an essential part of the investigation of infertility. Proximal tubal occlusion accounts for 10-25% of tubal factor infertility. Authors review the history, methods and value of the relevant diagnostic and therapeutic procedures of proximal tubal occlusion, as well as...
journal_title:Orvosi hetilap
pub_type: 历史文章,杂志文章
doi:10.1556/OH.2010.28834
更新日期:2010-07-04 00:00:00
abstract::151 members of 10 affected families with FAP have been registered at the authors' regional polyposis registry, among them 51 FAP patients were verified histologically. The disorder is autosomal dominant thus the chance for the inheritance of the mutated allele is fifty percent in the offspring of an affected patient. ...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:
更新日期:1997-12-14 00:00:00
abstract::In the past decade several novel findings point to the critical role of the skeleton in several homeostatic processes, including energy balance. The connection begins in the bone marrow with lineage allocation of mesenchymal stem cells to adipocytes or osteoblasts. Osteoblasts and adipocytes produce factors affecting ...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:10.1556/OH.2011.29147
更新日期:2011-07-17 00:00:00
abstract::The relative rarity of urogenital sinus and cloacal anomalies, the wide range of their anatomical variants furthermore the number of different surgical options makes the successful management of a child with such urogenital abnormality one of the greatest challenges to the paediatric surgeon. Based on their own experi...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:
更新日期:1995-08-27 00:00:00
abstract::Two cases of rare, benignant gastric tumors are reported. The suggest that while in the diagnosis of tumors with a mucous membrane involvement endoscopy has doubtless a leading role, tumors not infiltrating the mucous membrane are usually better recognizable by radiological (ultrasonography, computer tomography and do...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1999-11-07 00:00:00
abstract::This article reviews the recent changes in the understanding of acute pancreatitis pathophysiology emphasizing results deriving from the more detailed comprehension of the local and systemic aspects of the inflammatory process. The authors briefly discuss those theories that have been influencing the basic philosophie...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:
更新日期:2000-02-06 00:00:00
abstract::Bilateral renal artery stenosis was diagnosed noninvasively in the 17th gestational week, in a chronically hypertensive pregnant woman, by renal artery duplex ultrasound examination, MRI and MR angiography. Continuous monitoring of the mother and the fetus was performed. Blood pressure was stabilized by complex antihy...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1997-08-31 00:00:00
abstract::The author discusses about non-usual application of Cu containing intrauterine contraceptive device. An oophoropexy was performed on a 19 years old female suffering from Hodgkin disease. A Cu intrauterine contraceptive device was introduced into the uterine cavity to help in localising the radiological treatment. The ...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1989-02-26 00:00:00
abstract::Malignant and other chronic diseases cause the death of 2.5 million people in Europe annually. It is anticipated that this number will grow due to the aging of the European population. The death of a significant proportion of patients having progressive chronic disease is preceded by an extended end of life stadium. I...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:10.1556/650.2015.30272
更新日期:2015-10-18 00:00:00
abstract::Functional dyspepsia is a clinical syndrome defined by chronic or recurrent pain or discomfort in the upper abdomen of unknown origin. Dyspepsia is a very common condition, with a high prevalence in the general population. The multifactorial pathogenesis of dyspeptic symptoms is poorly defined. However, several factor...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:
更新日期:2004-04-04 00:00:00
abstract::The authors present a case report of a 13.5 yrs old girl. The first manifestation of her diabetes was the sudden decrease of her vision due to bilateral cataract. There was no report of perinatal of actual infection, previous trauma, radiation exposure or drug consumption. She was hypermetropic, for that she regularly...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1999-08-29 00:00:00
abstract::Vaccination is the main strategy to control severe dehydrating gastroenteritis caused by rotaviruses in early childhood. The availability of new generation rotavirus vaccines has led to an intensification of strain surveillance worldwide, in part, to gauge the impact of the possible vaccine-driven immune selection of ...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/OH.2009.28690
更新日期:2009-08-02 00:00:00
abstract::The authors discuss the role of nuclear medicine techniques in the modern diagnostics of breast cancer, including the methods currently used in Hungary and the future possibilities. ...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:10.1556/OH.2012.29256
更新日期:2012-01-08 00:00:00
abstract::Authors analysed 25 colorectal cancer lung metastases. Among them were 13 male 12 female. Ages ranged from 45 to 70 years. The lung nodules were discovered without any symptoms in 19 cases. The disease was localized on the right in 16 patients, in 7 on the left side and 2 others were bilateral. There were 19 solitary ...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1995-01-29 00:00:00
abstract::The redox homeostasis of patients with inflammatory bowel disease is not balanced because of malnutrition and malabsorption. The seriousness of this illness often hinders the intake and use of bioactive agents. We have just a small amount of knowledge about how patients can get access to these important materials. The...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:2006-06-11 00:00:00
abstract::The authors present the computer dynamic pedobarographic analyse method of the diabetic foot with case reports. The diabetic foot is described in the literature by interdisciplinar teams, and the authors recommend this method in the identification of the high pressure areas of the foot. By this way the orthotic specia...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1995-07-02 00:00:00
abstract::Myotonic dystrophy is one of the most common, autosomal dominantly inherited adult-onset muscle disorders. Two types of the disease are known: type 1 is characterized by distal weakness and myotonia, but type 2 is associated with proximal weakness and milder clinical course. It is also called as Steinert Disease, whic...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/650.2019.31505
更新日期:2019-09-01 00:00:00
abstract::The authors detected Epstein-Barr virus (EBV) virus capsid (VCA) antibodies of IgM and IgG type together with EBNA and heterophil antibodies in the sera collected from 1882 unselected patients without infectious mononucleosis. Out of them IgM type antibodies were found in 123 cases and in an additional group of 30 pat...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1996-07-28 00:00:00
abstract::Five patients suffering from transient myocardial ischemia of the newborn are discussed. The role of two-dimensional doppler-echocardiography is emphasized in establishing the diagnosis. Tricuspid insufficiency due to perinatal asphyxia can be detected easier by ultrasound than by any other cardiac examination. Cardia...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1991-02-03 00:00:00