Abstract:
PRIMARY OBJECTIVE:We aimed to assess the utility of bispectral index (BIS) monitoring to diagnose brain death (BD) in patients with severe traumatic brain injury (TBI). RESEARCH DESIGN AND METHODS:A prospective observational study was conducted for patients with severe TBI between 2012 and 2014. MAIN OUTCOMES AND RESULTS:This study included 62 patients with a mean age of 32.5 ± 10.5 years. Nine patients had BD on admission with a sustainable BIS value of 0. Fifty-three patients were not initially diagnosed with BD with BIS values of 2-56. Forty-four patients deteriorated to BD, and their respective BIS values progressively decreased to 0. Nine patients with mean BIS of 39.2 ± 9.0 recovered and were transferred to a specialized high dependency unit. BIS values showed positive correlation with the Glasgow Coma Score (GCS) on admission (r = 0.43, p = 0.001). Survivors had higher BIS values than those who were initially declared BD or those who died during the hospitalization course (p = 0.001). CONCLUSION:BIS values have a significant correlation with initial GCS and can assist in the early detection of BD in patients with severe acute TBI. Further larger studies are needed to support our findings.
journal_name
Brain Injjournal_title
Brain injuryauthors
Mahmood S,El-Menyar A,Shabana A,Mahmood I,Asim M,Abdelrahman H,Al-Thani Hdoi
10.1080/02699052.2017.1330966subject
Has Abstractpub_date
2017-01-01 00:00:00pages
1382-1386issue
10eissn
0269-9052issn
1362-301Xjournal_volume
31pub_type
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