Abstract:
PRIMARY OBJECTIVE:To understand the temporal evolution of brain reorganization during recovery from stroke. RESEARCH DESIGN:A patient who suffered left middle cerebral artery stroke 9 months earlier was studied on three occasions, approximately 1 month apart. METHODS AND PROCEDURES:Brain activation was studied using functional Magnetic Resonance Imaging (fMRI). During each session, the patient performed a finger-to-thumb opposition task, which involved one bimanual and two unimanual conditions. Each condition consisted of overt movement of fingers and imagery of the same task. RESULTS:With recovery, greater recruitment was observed of the affected primary motor cortex (M1) and a decrease in activation of the unaffected M1 and supplementary motor area. In addition, the widespread activation of brain areas seen during the initial session changed to a more focused pattern of activation as the patient recovered. Imagery tasks resulted in similar brain activity as overt execution pointing to imagery as a potential tool for rehabilitation.
journal_name
Brain Injjournal_title
Brain injuryauthors
Nair DG,Fuchs A,Burkart S,Steinberg FL,Kelso JAdoi
10.1080/02699050500149858subject
Has Abstractpub_date
2005-12-01 00:00:00pages
1165-76issue
13eissn
0269-9052issn
1362-301Xpii
G43LQ37122170R08journal_volume
19pub_type
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