Thyroid gland: US in patients with Hodgkin disease treated with radiation therapy in childhood.

Abstract:

:The authors retrospectively assessed with sonography the prevalence of thyroid gland abnormalities in 30 patients who underwent radiation therapy for Hodgkin disease between 1962 and 1984. Doses ranged from 3,000 to 4,500 rad (3,000-4,500 cGy). Abnormalities were found in the sonograms of 24 patients and included unilateral (n = 6) or bilateral (n = 2) atrophy; multiple hypoechoic lesions smaller than 0.75 cm (n = 18); and dominant cystic (n = 2), solid (n = 3), or complex lesions (n = 4) larger than 0.75 cm. The risk of development of an abnormality increased as the time from irradiation increased and was comparable between patients who did and did not receive chemotherapy as part of the treatment regimen. Although the pathologic correlates of the various abnormalities seen on sonograms may differ, the findings indicate a need for long-term follow-up of patients who underwent cervical irradiation for Hodgkin disease.

journal_name

Radiology

journal_title

Radiology

authors

Stewart RR,David CL,Eftekhari F,Ried HL,Fuller LM,Fornage BD

doi

10.1148/radiology.172.1.2662250

subject

Has Abstract

pub_date

1989-07-01 00:00:00

pages

159-63

issue

1

eissn

0033-8419

issn

1527-1315

journal_volume

172

pub_type

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