CT colonography: automated measurement of colonic polyps compared with manual techniques--human in vitro study.

Abstract:

PURPOSE:To prospectively investigate the relative accuracy and reproducibility of manual and automated computer software measurements by using polyps of known size in a human colectomy specimen. MATERIALS AND METHODS:Institutional review board approval was obtained for the study; written consent for use of the surgical specimen was obtained. A colectomy specimen containing 27 polyps from a 16-year-old male patient with familial adenomatous polyposis was insufflated, submerged in a container with solution, and scanned at four-section multi-detector row computed tomography (CT). A histopathologist measured the maximum dimension of all polyps in the opened specimen. Digital photographs and line drawings were produced to aid CT-histologic measurement correlation. A novice (radiographic technician) and an experienced (radiologist) observer independently estimated polyp diameter with three methods: manual two-dimensional (2D) and manual three-dimensional (3D) measurement with software calipers and automated measurement with software (automatic). Data were analyzed with paired t tests and Bland-Altman limits of agreement. RESULTS:Seven polyps (

journal_name

Radiology

journal_title

Radiology

authors

Taylor SA,Slater A,Halligan S,Honeyfield L,Roddie ME,Demeshski J,Amin H,Burling D

doi

10.1148/radiol.2421052068

subject

Has Abstract

pub_date

2007-01-01 00:00:00

pages

120-8

issue

1

eissn

0033-8419

issn

1527-1315

pii

2421052068

journal_volume

242

pub_type

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