当前位置： SCI文献检索 > TRANSPLANTATION PROCEEDINGS期刊下所有文献 > Impact of Early Low-Grade Proteinuria and Allograft Dysfunction on Survival in Expanded Criteria Donor Kidney Transplant Recipients.

Impact of Early Low-Grade Proteinuria and Allograft Dysfunction on Survival in Expanded Criteria Donor Kidney Transplant Recipients.

Abstract：

INTRODUCTION:Recent studies have demonstrated a relationship between low-grade proteinuria and worse graft survival, but this has not been fully studied in expanded criteria donor (ECD) kidney transplant recipients. AIM:The aim of this study was to assess whether the combination of early low-grade proteinuria (<1 g/d) and allograft dysfunction at the third month post-transplantation predicts outcomes in terms of survival in ECD kidney transplant recipients. MATERIAL AND METHODS:We studied a cohort of 269 ECD kidney transplant recipients subdivided into 4 groups according to clinically relevant proteinuria (300 mg/d) and median creatinine (Cr; 1.7 mg/dL; interquartile range, 1.4-2.1 mg/dL) at the third month post-transplantation: Group A (Cr <1.7 mg/dL and proteinuria <300 mg/24 h; n = 97), Group B (Cr <1.7 mg/dL and proteinuria ≥300 mg/24 h; n = 38), Group C (Cr ≥1.7 mg/dL and proteinuria <300 mg/24 h; n = 79), and Group D (Cr ≥1.7 mg/dL and proteinuria ≥300 mg/24 h; n = 55). RESULTS:Death-censored graft survival was significantly lower in Group D compared with the rest (P < .007). Multivariate Cox regression analysis using fixed covariates showed that the combination of low-grade proteinuria and a lower estimated glomerular filtration rate (eGFR) as associated with graft failure (hazard rate [HR] 2.5, 95% confidence interval [CI], 1.09-5.97; P = .03). CONCLUSIONS:The early association of low-grade proteinuria and allograft dysfunction represents an important risk factor for graft loss in ECD kidney transplant recipients. Strategies to optimize renal function could improve the outcome in this specific population.

journal_name

Transplant Proc

journal_title

Transplantation proceedings

authors

López V,Cabello M,Ruíz-Esteban P,Sola E,Gutiérrez C,Jironda C,Burgos D,González-Molina M,Hernández D

doi

10.1016/j.transproceed.2015.08.045

subject

Has Abstract

pub_date

2015-11-01 00:00:00

pages

2611-4

issue

9

eissn

0041-1345

issn

1873-2623

pii

S0041-1345(15)00922-7

journal_volume

47

pub_type

杂志文章

相关文献

TRANSPLANTATION PROCEEDINGS文献大全
  • Experience with cyclosporine in the Canary Islands.

    abstract：:Cyclosporine (CsA) is currently the basis of most immunosuppressive protocols after solid organ transplantation. The introduction of Neoral, a new microemulsion formulation of CsA, and more recently a range of adjunctive immunosuppressants have further enhanced short-term efficacy and tolerability of CsA-based immunos...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章,评审

    doi：10.1016/j.transproceed.2003.12.030

    authors： Hernández D

    更新日期：2004-03-01 00:00:00

  • A new kidney allocation policy in Chile: computer-based simulations.

    abstract：INTRODUCTION:Kidney allocation should reach a balance between equity and efficiency. In Chile kidneys are allocated based on ABO matching, first to medical priorities and then according to a point scheme considering human leukocyte antigen (HLA) match (60%), waiting list time (20%), and panel-reactive antibodies (PRA; ...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2013.01.012

    authors： Domínguez J,Harrison R,Atal R,Muñoz F

    更新日期：2013-05-01 00:00:00

  • Multidrug-resistant gram-positive infections in patients with ventricular assist devices: the role of daptomycin.

    abstract：OBJECTIVES:The rate of infection in patients who require ventricular assist devices (VADs) is estimated at more than 35%. Infections with multidrug-resistant (MDR) organisms in VAD recipients present a high mortality rate. Daptomycin (Cubicin, Novartis, Nuremberg, Germany), a new cyclic lipopeptide antibiotic, is usefu...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2009.06.126

    authors： Beiras-Fernandez A,Kur F,Kiefer S,Sodian R,Schmoeckel M,Weis M,Reichart B,Weis F

    更新日期：2009-07-01 00:00:00

  • Prevalence and manifestations of tuberculosis in renal transplant recipients: a single-center experience in Thailand.

    abstract：:This retrospective review presented the prevalence and manifestations of tuberculosis among renal transplant recipients in our center between 1987 and mid 2007. The prevalence of tuberculosis was 5/151 (3.3%) recipients with a median age of 49 years (range = 38-55). The median time of diagnosis after transplantation w...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2008.06.020

    authors： Ruangkanchanasetr P,Natejumnong C,Kitpanich S,Chaiprasert A,Luesutthiviboon L,Supaporn T

    更新日期：2008-09-01 00:00:00

  • Elevated Monocyte Count and Loss of Renal Function in Renal Transplant Patients.

    abstract：BACKGROUND:Rejection is an important factor affecting graft function in renal transplant patients. Development of acute rejection even after induction treatment suggests that humoral and cellular immune systems are not the only mechanisms responsible for this event. The innate immune system can play roles in rejection....

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2020.02.176

    authors： Buberci R,Paydas S

    更新日期：2020-12-01 00:00:00

  • Severe rhabdomyolysis and acute renal failure in a kidney transplant patient treated with tacrolimus and chimaeric CD25 monoclonal antibody.

    abstract：:Recently observations of rhabdomyolysis in patients treated with tacrolimus have been reported. The authors present a kidney transplant patient who had an epileptic seizures, severe rhabdomyolysis, and acute renal failure. The patient was initially immunosuppressed with tacrolimus and chimeric CD25 monoclonal antibody...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2004.03.019

    authors： Fontana I,Ginevri F,Basile G,Beatini M,Bertocchi M,Bonifazio L,Saltalamacchia L,Ghinolfi D,Santori G,Valente R,Perfumo F,Valente U

    更新日期：2004-04-01 00:00:00

  • Increased expression of renin in chronic allograft nephropathy.

    abstract：BACKGROUND:Chronic allograft nephropathy (CAN) is the main cause of renal transplant failure in the first decade posttransplant. The precise pathogenetic mechanism for CAN is not completely understood. A possible role of renin-angiotensin system for CAN has been suggested through clinical observations that angiotensin-...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2005.05.001

    authors： Oka K,Moriyama T,Takahara S,Naruse M,Namba Y,Ichimaru N,Kyo M,Kokado Y,Okuyama A,Ito T,Imai E,Aozasa K

    更新日期：2005-06-01 00:00:00

  • Cerebral blood flow in fulminant hepatitis.

    abstract：:Fulminant hepatic failure (FHF) is often complicated with cerebral edema, intracranial hypertension, and coma. Cytotoxic and vasogenic factors have been recognized in the etiology of cerebral edema. One of the main causes seems to be the accumulation of glutamine in astrocytes, which is produced from ammonia and the e...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2006.01.040

    authors： Feltracco P,Serra E,Barbieri S,Tiberio I,Rizzi S,Salvaterra F

    更新日期：2006-04-01 00:00:00

  • Simultaneous Determination of Everolimus, Sirolimus, Tacrolimus, and Cyclosporine-A by Mass Spectrometry.

    abstract：:Measurement of immunosuppressive drug concentrations cyclosporine A (CyA), tacrolimus (TAC), sirolimus (SIR), and everolimus (EVE) in blood is an important application of therapeutic drug monitoring. These immunosuppressive agents are used in combined regimens and nowadays the liquid chromatography and tandem mass spe...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2020.01.077

    authors： Dinéia Perez J,Sanches Aragão D,Aparecida Ronchi F,Febba AC,Rosso CF,Tedesco-Silva Junior H,Medina de Abreu Pestana JO,Casarini DE

    更新日期：2020-06-01 00:00:00

  • Impact of the 2011 Great East Japan Earthquake on the resumption of alcohol consumption after living-donor liver transplantation for alcoholic cirrhosis: a report of two cases.

    abstract：:Alcoholic liver disease (ALD) is a leading indication for liver transplantation (LT) in Western countries. The rate of resumption of alcohol abuse is 7% to 95% after LT for ALD. A high prevalence of alcohol abuse has been observed in disaster-exposed populations; however, little is known about the association between ...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2013.09.048

    authors： Nakanishi C,Kawagishi N,Sato K,Miyagi S,Takeda I,Ohuchi N

    更新日期：2014-04-01 00:00:00

  • Liver transplantation from maastricht category 2 non-heart-beating donors: a source to increase the donor pool?

    abstract：INTRODUCTION:The demand for liver transplantation has increasingly exceeded the supply of cadaver donor organs. Non-heart-beating donors (NHBDs) may be an alternative to increase the cadaver donor pool. The outcome of 20 liver transplants from Maastricht category 2 NHBD was compared with that of 40 liver transplants fr...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2004.03.027

    authors： Otero A,Gómez-Gutiérrez M,Suárez F,Arnal F,Fernández-García A,Aguirrezabalaga J,García-Buitrón J,Alvarez J,Máñez R

    更新日期：2004-04-01 00:00:00

  • Early hepatic artery thrombosis after liver transplantation: diagnosis and treatment.

    abstract：BACKGROUND:Hepatic artery thrombosis (HAT) occurs in 3% to 9% of all liver transplantations with acute graft failure as a possible sequel. METHODS:Eleven episodes of HAT were identified among 256 orthotropic liver transplantations (whole, LDCT, split) performed on 253 patients between April 1993 and July 2006. HAT was...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2007.02.017

    authors： Nikeghbalian S,Kazemi K,Davari HR,Salahi H,Bahador A,Jalaeian H,Khosravi MB,Ghaffari S,Lahsaee M,Alizadeh M,Rasekhi AR,Nejatollahi SM,Malek-Hosseini SA

    更新日期：2007-05-01 00:00:00

  • Body image in kidney transplantation.

    abstract：INTRODUCTION:Psychologic disturbances are becoming more common in kidney transplantation, owing to effects of immunosuppressive therapy. In this study, we explored the incidence and specifity of psychopathology among kidney transplant patients. Twenty kidney transplant recipients underwent the Machover Draw-A-person te...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2010.03.071

    authors： De Pasquale C,Pistorio ML,Sorbello M,Parrinello L,Corona D,Gagliano M,Giuffrida G,Giaquinta A,Sinagra N,Zerbo D,Veroux P,Veroux M

    更新日期：2010-05-01 00:00:00

  • Anxiety, depression and emotional profile in renal transplant recipients and healthy subjects: a comparative study.

    abstract：BACKGROUND:Renal transplantation is a well established treatment for end-stage renal disease. However, recipients have been shown to develop emotional distress and affective disorders, such as anxiety and depression, associated with a compromised quality of life. Some accounts report an improvement of affective disorde...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2010.08.056

    authors： Pascazio L,Nardone IB,Clarici A,Enzmann G,Grignetti M,Panzetta GO,Vecchiet C

    更新日期：2010-11-01 00:00:00

  • Modified liver-free multivisceral transplantation for a metastatic small bowel neuroendocrine tumor: a case report.

    abstract：:Neuroendocrine tumors originating from the small bowel frequently metastasize to the lymph nodes and/or liver. Although surgical extirpation of the primary tumor and locoregional metastases epitomizes the management of patients with such tumors, this is not always possible with conventional surgical techniques. Nonres...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2015.01.007

    authors： Frilling A,Giele H,Vrakas G,Reddy S,Macedo R,Al-Nahhas A,Wasan H,Clift AK,Gondolesi GE,Vianna RM,Friend P,Vaidya A

    更新日期：2015-04-01 00:00:00

  • Differential gene expression profile of porcine livers subjected to warm ischemia alone.

    abstract：BACKGROUND:Livers exposed to warm ischemia (WI) are increasingly used for transplantation. The molecular mechanisms activated by WI alone (prior to procurement and transplantation) are not understood. To elucidate the pathways involved, we used microarrays to investigate the gene expression in porcine livers exposed to...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2011.09.028

    authors： Vekemans K,Balligand E,Liu Q,Heedfeld V,Wylin T,Monbaliu D,Pirenne J,van Pelt J

    更新日期：2011-11-01 00:00:00

  • Severe cardiac allograft dysfunction without endomyocardial biopsy signs of cellular rejection: incidence and management.

    abstract：:Acute dysfunction of cardiac allograft without evidence of cellular rejection is a potentially fatal complication of heart transplantation that suggests a humoral origin. In clinical practice, humoral rejection (HR) is suspected when there is evidence of severe allograft dysfunction but endomyocardial biopsy (EMB) sho...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2004.03.033

    authors： Veiga Barreiro A,Crespo Leiro M,Doménech García N,Paniagua MJ,Vázquez Martul E,González Cuesta M,Ramírez C,Juffé Stein A,Castro Beiras A

    更新日期：2004-04-01 00:00:00

  • Use of oral sildenafil in patients with irreversible pulmonary hypertension not eligible for heart transplantation.

    abstract：:Heart transplantation is contraindicated in patients with acute irreversible pulmonary hypertension (PH), but new drugs are opening up therapeutic possibilities. Sildenafil citrate is a nonselective pulmonary vasodilator that is being used in our hospital to treat several patients with PH and which has allowed the inc...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2005.02.013

    authors： Gómez-Moreno S,Lage E,Hernández A,Campos A,Cabezón S,Ordóñez A,Hinojosa R

    更新日期：2005-04-01 00:00:00

  • Irradiation is an early determinant of endothelial injury during hematopoietic stem cell transplantation.

    abstract：OBJECTIVE:We investigated the degree and the time course of endothelial injury in mice pretreated with lethal or reduced-intensity irradiation administered before transplantation. MATERIALS AND METHODS:Six- to eight-week-old female mice were randomly allocated into three groups: lethal-intensity irradiation (8.5 Gy, g...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2008.08.062

    authors： Zeng L,Yan Z,Wang L,Du B,Pan X,Xu K

    更新日期：2008-10-01 00:00:00

  • Brain Death: Is It a Misunderstood Concept Among Nursing Students in the South of Poland?

    abstract：BACKGROUND:The objective of the present study was to analyze the knowledge and acceptance of the brain death (BD) concept among nursing students. METHODS:The study was undertaken in the academic year of 2011 to 2012 in nursing students from the University of the South of Poland. The sample was carried out in compulsor...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2015.10.016

    authors： Mikla M,Ríos A,López-Navas A,Kasper M,Brzostek T,Martínez-Alarcón L,Ramis G,Ramírez P,López-Montesinos MJ

    更新日期：2015-11-01 00:00:00

  • Changes in Renal Function After Heart Transplantation.

    abstract：:Renal function after heart transplantation (HTx) typically follows a biphasic pattern and an initial decay within 1 to 2 years. Trajectory of renal function after HTx is less reported, especially in Asia. The aims of this cohort study were to describe the changes in HTx recipients' serum creatinine and estimated glome...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2018.02.196

    authors： Tsao CI,Ting M,Chou NK,Chi NH,Chen YS,Huang SC,Tsan CY,Wang CH,Yu HY,Shun CT,Wang SS

    更新日期：2018-11-01 00:00:00

  • Results of retransplantation for primary nonfunction in a single center.

    abstract：INTRODUCTION:Early graft dysfunction has a negative impact on allograft and patient survivals, evolving to retransplantation or death in the majority of cases. The outcome of a second liver transplant is usually worse than the first procedure. Considering the increasing number of recipients on the waiting list, and the...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2010.12.003

    authors： Coelho MP,Afonso RC,Hidalgo R,Felga G,Almeida MD,Della-Guardia B,Rezende MB,Meira-Filho SP,Ferraz-Neto BH

    更新日期：2011-01-01 00:00:00

  • Brain death caused by electric shock and organ donation in children.

    abstract：INTRODUCTION:There are still few publications about brain death caused by electric shock and the use of organs for donation in this situation. We sought to present our experience, with brain dead pediatric donors caused by electric shock. MATERIAL AND METHODS:Notification registers of potential donors were analyzed fr...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2007.01.033

    authors： Todeschini DP,Maito ED,Maldotti A,Moreira AL,Capaverde FB,Figueiredo FM,Oliveira DM,Costa MG,Hoelfmann N,Londero GG,Leães PE,Garcia VD

    更新日期：2007-03-01 00:00:00

  • The Course of Ulcerative Colitis After Pediatric Liver Transplantation for Sclerosing Cholangitis.

    abstract：BACKGROUND:Primary sclerosing cholangitis (PSC) and autoimmune sclerosing cholangitis (ASC) are often associated with ulcerative colitis (UC). The impact on the course of UC remains unclear, and up-to-date evidence in pediatric populations is scarce. The aim of the study was to analyze the course of UC in pediatric pat...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2020.09.011

    authors： Osiecki M,Kierkuś J,Pawłowska J,Woźniak M,Jankowska I,Teisseyre M,Dądalski M,Jarzębicka D,Stefanowicz M,Czubkowski P

    更新日期：2021-01-01 00:00:00

  • Galectin-1 in stable liver transplant recipients.

    abstract：INTRODUCTION:The achievement of a state of tolerance and minimization of the immunosuppressive load form part of the "Holy Grail" in solid organ transplantation. Galectin-1 recently has been described to be involved in the maintenance of a tolerant environment, but there is no evidence of its role in human liver transp...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2014.12.001

    authors： García MJ,Jurado F,San Segundo D,López-Hoyos M,Iruzubieta P,Llerena S,Casafont F,Arias M,Puente Á,Crespo J,Fábrega E

    更新日期：2015-01-01 00:00:00

  • Endoscopic management of urologic complications following renal transplantation: impact of ureteral anastomosis.

    abstract：OBJECTIVE:To evaluate the success of ureteral stent placement to treat or prepare for surgical treatment of urologic complications after renal transplantation, according to a type of ureteral anastomosis. PATIENT AND METHODS:From May 1989 to December 2006, we performed 703 kidney transplantations including 412 extrave...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2009.08.046

    authors： Tillou X,Raynal G,Demailly M,Hakami F,Saint F,Petit J

    更新日期：2009-10-01 00:00:00

  • Toxoplasmic Encephalitis Followed by Primary EBV-Associated Post-Transplant Lymphoproliferative Disorder of the Central Nervous System in a Patient Undergoing Allogeneic Hematopoietic Stem Cell Transplant: A Case Report.

    abstract：:Toxoplasmic encephalitis (TE) and post-transplant lymphoproliferative disorder of the central nervous system (CNS-PTLD) are major complications after allogeneic hematopoietic stem cell transplant (allo-SCT); both are fatal without timely diagnosis and disease-specific treatment. Differential diagnosis of TE and CNS-PT...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2020.08.002

    authors： Mayumi A,Yamashita T,Matsuda I,Hikosaka K,Fujino S,Norose K,Kato Y,Hirota S,Nakajima T,Ogawa H,Ikegame K

    更新日期：2020-11-01 00:00:00

  • It takes time after bilateral nephrectomy for better control of resistant hypertension in renal transplant patients.

    abstract：UNLABELLED:Severe resistant hypertension in end-stage renal disease patients has traditionally been an indication for bilateral nephrectomy (BN) before kidney transplantation. Nevertheless the influence of BN on successful control of hypertension has not been well documented. We sought to clarify the effect of BN on bl...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2010.04.014

    authors： Gawish AE,Donia F,Fathi T,Al-Mousawi M,Samhan M

    更新日期：2010-06-01 00:00:00

  • Susceptibility of porcine keratocytes to immune-mediated damage in xeno-related rejection.

    abstract：:We admixed cultured porcine keratocytes or corneal endothelial cells in the presence of human sera or peripheral blood mononuclear cells (PBMCs) for 4 to 72 hours to investigate their immune-related susceptibilities to xeno-related rejection. We evaluated complement deposition at 48 hours by flow cytometry after stain...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2007.12.024

    authors： Kim MK,Oh JY,Lee HI,Ko JH,Lee HJ,Lee JH,Wee WR

    更新日期：2008-03-01 00:00:00

  • Carbapenem-Resistant Klebsiella Pneumoniae Infections Early After Liver Transplantation: A Single-Center Experience.

    abstract：:The aims of this study were to define in a cohort of 310 liver transplant recipients, the incidence of post-liver transplantation (LT) non-carbapenem-resistant Klebsiella pneumoniae (CRKP) and CRKP infections, pre- and post-LT CRKP colonization, CRKP-associated mortality, and risk factors for non-CRKP and CRKP infecti...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2017.02.028

    authors： Mazza E,Prosperi M,Panzeri MF,Limuti R,Nichelatti M,De Gasperi A

    更新日期：2017-05-01 00:00:00