Abstract：
:Synchronous averaging over time locked single-trial of event-related potential (ERP) is known as the simplest scheme to extract P300 component. This method assumes the P300 features are invariant through the time while they are affected by factors like brain fatigue and habitation. In this study, a new scheme is proposed termed as time-varying time-lag blind source separation (TT-BSS) which is upon the second order statistics of signal to separate P300 waveform from the background electroencephalogram (EEG) while it captures the time variation of P300 component. The time-lag parameter for all channels is determined by maximizing the correlation (similarity) between two successive trials. As the time-lag parameter is varying by time (trial to trial), an average is taken over the time-lag covariance matrices of all two consecutive trials. TT-BSS finally estimates a transform (separating matrix) by joint diagnolization of the covariance matrix of trials and the averaged covariance matrix of the time varying time-lag. To assess the proposed scheme, synthetic and real EEGs containing P300 are used. The EEG signals were collected from twenty schizophrenic and twenty age-matched normal subjects via 20 channels through the resting state and in presence of the oddball audio stimulus. Empirical achievements over the simulated and real EEGs imply on the superiority of TT-BSS in dynamic estimation of P300 characteristics compared to state-of-the-art counterparts such as constant time-lag BSS, constrained BSS and synchronous averaging.
journal_name
Comput Methods Programs Biomedjournal_title
Computer methods and programs in biomedicineauthors
Sabeti M,Boostani Rdoi
10.1016/j.cmpb.2017.04.014subject
Has Abstractpub_date
2017-07-01 00:00:00pages
95-102eissn
0169-2607issn
1872-7565pii
S0169-2607(16)31170-1journal_volume
145pub_type
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