Abstract:
:Hexosaminidase, polyamines and lipid-bound sialic acid are a few tumour-associated markers which are significantly elevated both in urine and serum of patients with haematopoietic malignancy, in direct correlation to dedifferentiation. Our computer database incorporates these parameters and predicts the clinical response based on the baseline values of these tumour-associated markers. This completely menu-driven user-friendly database can be routinely applied in tumour management and can access a billion records. The results of our evaluation confirm that most clinical assessments by a physician working blind are in agreement with the computer prediction, thus encouraging the use of microcomputers in patient management.
journal_name
Comput Methods Programs Biomedjournal_title
Computer methods and programs in biomedicineauthors
Venkatanarayanan S,Nagarajan Bdoi
10.1016/0169-2607(90)90032-5subject
Has Abstractpub_date
1990-01-01 00:00:00pages
63-70issue
1eissn
0169-2607issn
1872-7565pii
0169-2607(90)90032-5journal_volume
31pub_type
杂志文章abstract:BACKGROUND AND OBJECTIVE:This paper presents an improved scheme able to perform accurate segmentation and classification of cancer nuclei in immunohistochemical (IHC) breast tissue images in order to provide quantitative evaluation of estrogen or progesterone (ER/PR) receptor status that will assist pathologists in can...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2018.08.005
更新日期:2018-10-01 00:00:00
abstract::Following the paper publication of practice guidelines for the management of febrile patients returning from the tropics, we constructed a consultation website that comprises a decision chart and specific diagnostic features providing medical diagnostic assistance to primary care physicians. We then integrated a resea...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2006.09.004
更新日期:2007-01-01 00:00:00
abstract::This paper presents a preprocessing technique for improving the classification of electroencephalographic (EEG) data in brain-computer interfaces (BCI) for the case of realistic measuring conditions, such as low signal-to-noise ratio (SNR), reduced number of measuring electrodes, and reduced amount of data used to tra...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2009.05.005
更新日期:2010-01-01 00:00:00
abstract::The noninvasive fetal electrocardiography is a source of more precise information on the fetal heart activity than the measurements based on Doppler ultrasound signals. However, the clinical diagnostic applications of this technique are limited by difficulty with successful detection of small amplitude fetal QRS compl...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2009.09.005
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Skin cancer is the commonest form of cancer in the worldwide population. Non-invasive and non-contact imaging modalities are being used for the screening of melanoma and other cutaneous malignancies to endorse early detection and prevention of the disease. Traditionally it has been a problem fo...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2019.06.018
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Dizziness is a major consequence of imbalance and vestibular dysfunction. Compared to surgery and drug treatments, balance training is non-invasive and more desired. However, training exercises are usually tedious and the assessment tool is insufficient to diagnose patient's severity rapidly. ...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2014.04.014
更新日期:2014-10-01 00:00:00
abstract::The urinary flow rates of normal individuals depend on the initial bladder volume in a non-linear fashion (J. Urol. 109 (1973) 874). A flow rate nomogram was developed by Siroky, Olsson and Krane, (J. Vol. 122 (1979) 665), taking the non-linear relationship into account, as an aid in the interpretation of urinary flow...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/0169-2607(93)90030-o
更新日期:1993-04-01 00:00:00
abstract::The purpose of this study was to evaluate the clinical efficacy of 3D reconstruction of the tracheobronchial system using spiral CT. A total of 25 patients with tracheobronchial abnormalities, stenosis (n = 21) and fistula with esophagus (n = 4), underwent a single breathhold spiral CT (5 mm collision, 5 mm)/s increme...
journal_title:Computer methods and programs in biomedicine
pub_type: 临床试验,杂志文章
doi:10.1016/s0169-2607(98)00053-4
更新日期:1998-08-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The detection of optic nerve head (ONH) in retinal fundus images plays a key role in identifying Diabetic Retinopathy (DR) as well as other abnormal conditions in eye examinations. This paper presents a method and its associated software towards the development of an Android smartphone app base...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2018.05.004
更新日期:2018-08-01 00:00:00
abstract::A software system was designed whose aim is to support everyday scientific research of physicians in different fields of medicine. DREAM is a shell-like tool which can be customized embedding in it the desirable structure of a particular medical problem. Various basic statistical analyses are provided along with the d...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/0169-2607(93)90001-2
更新日期:1993-06-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Shape prior models play a vital role for segmentation in medical image analysis. These models are most effective when shape variations can be captured by a parametric distribution, and sufficient training data is available. However, in the absence of these conditions, results are invariably muc...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2020.105760
更新日期:2020-09-24 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Hypokinetic dysarthria (HD) is a frequent speech disorder associated with idiopathic Parkinson's disease (PD). It affects all dimensions of speech production. One of the most common features of HD is dysprosody that is characterized by alterations of rhythm and speech rate, flat speech melody, ...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2015.12.011
更新日期:2016-04-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Early-phase virtual screening of candidate drug molecules plays a key role in pharmaceutical industry from data mining and machine learning to prevent adverse effects of the drugs. Computational classification methods can distinguish approved drugs from withdrawn ones. We focused on 6 data set...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2017.02.004
更新日期:2017-04-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:In clinical examinations and brain-computer interface (BCI) research, a short electroencephalogram (EEG) measurement time is ideal. The use of event-related potentials (ERPs) relies on both estimation accuracy and processing time. We tested a particle filter that uses a large number of particle...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2015.11.006
更新日期:2016-03-01 00:00:00
abstract::The analysis of human motion from video has been the object of interest for many application areas, these including surveillance, control, biomedical analysis, video annotation etc. This paper addresses the advances within this topic in relation to epilepsy, a domain where human motion is with no doubt one of the most...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章,评审
doi:10.1016/j.cmpb.2012.08.005
更新日期:2012-12-01 00:00:00
abstract::In this study, the virtual reality (VR) proprioception rehabilitation system was developed for stroke patients to use proprioception feedback in upper limb rehabilitation by blocking visual feedback. To evaluate its therapeutic effect, 10 stroke patients (onset>3 month) trained proprioception feedback rehabilitation f...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2013.09.006
更新日期:2014-01-01 00:00:00
abstract::In this article the development of a computer system for General Practice, ELIAS, is described. The use of the 4th-generation software toolkit AIDA proved to be very helpful in increasing the speed of development as well as the quality of the ELIAS software. The programming support that AIDA offered, not only in incre...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/0169-2607(87)90086-1
更新日期:1987-11-01 00:00:00
abstract::Patient survival is one of the most important measures of cancer patient care (the diagnosis and treatment of cancer). The optimal method for monitoring the progress of patient care across the full spectrum of provider settings is through the population-based study of cancer patient survival, which is only possible us...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2005.08.002
更新日期:2005-12-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:With ongoing interest in CNT nanofluids and materials in biotechnology, energy and environment, microelectronics, composite materials etc., the current investigation is carried out to analyze the effects of variable viscosity and thermal conductivity of CNT nanofluids flow driven by cilia indu...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2016.08.001
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The application of medical knowledge strongly affects the performance of intelligent diagnosis, and method of learning the weights of medical knowledge plays a substantial role in probabilistic graphical models (PGMs). The purpose of this study is to investigate a discriminative weight-learning...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2018.01.005
更新日期:2018-03-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:T-wave alternans (TWA) is a fluctuation of the ST-T complex occurring on an every-other-beat basis of the surface electrocardiogram (ECG). It has been shown to be an informative risk stratifier for sudden cardiac death, though the lack of gold standard to benchmark detection methods has promote...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2017.04.005
更新日期:2017-07-01 00:00:00
abstract:BACKGROUND:Diabetic retinopathy (DR) is one of the leading causes of blindness globally. Earlier detection and timely treatment of DR are desirable to reduce the incidence and progression of vision loss. Currently, deep learning (DL) approaches have offered better performance in detecting DR from retinal fundus images....
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2020.105320
更新日期:2020-07-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Changes in mechano-electrochemical properties of articular cartilage play an essential role in the majority of cartilage diseases. Despite of this importance, the specific effect of each parameter into tissue behavior remains still obscure. Parametric computational modeling of cartilage can pro...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2015.09.018
更新日期:2015-12-01 00:00:00
abstract::The use of a microcomputer in lung sound-analysis is described. The system was used experimentally in order to evaluate automated auscultation as a mean for improving the sensitivity of pulmonary health mass screening. The sound signals from four custom-made piezoelectric transducers, affixed at specific locations on ...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/0169-2607(93)90045-m
更新日期:1993-05-01 00:00:00
abstract::We discuss how vocal disorders can be post-corrected via a simple nonlinear noise reduction scheme. This work is motivated by the need of a better understanding of voice dysfunctions. This would entail a 2-fold advantage for affected patients: Physicians can perform better surgical interventions and on the other hand ...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/s0169-2607(01)00161-4
更新日期:2002-05-01 00:00:00
abstract:BACKGROUND:Breast cancer is the most common cancer affecting females worldwide. Breast cancer survivability prediction is challenging and a complex research task. Existing approaches engage statistical methods or supervised machine learning to assess/predict the survival prospects of patients. OBJECTIVE:The main objec...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2017.12.011
更新日期:2018-03-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Probabilistic topic models provide an unsupervised method for analyzing unstructured text. These models discover semantically coherent combinations of words (topics) that could be integrated in a clinical automatic summarization system for primary care physicians performing chart review. Howeve...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2015.10.014
更新日期:2016-02-01 00:00:00
abstract::Sleep-related breathing disorders are common in adults and they have a significant impact on vigilance and quality of life. Previous studies have shown the validity of the static-charge-sensitive bed (SCSB) in monitoring breathing abnormalities during sleep. A whole nights sleep study produces a signal with considerab...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/s0169-2607(99)00043-7
更新日期:2000-03-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Accurate segmentation of prostate and its zones constitute an essential preprocessing step for computer-aided diagnosis and detection system for prostate cancer (PCa) using diffusion-weighted imaging (DWI). However, low signal-to-noise ratio and high variability of prostate anatomic structures ...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2020.105572
更新日期:2020-11-01 00:00:00
abstract::A software package for the IBM PC computer is presented to facilitate the analysis of three-channel Lissajous' trajectories (3CLT) of auditory brainstem potentials. The program deals with 4-channel numeric or ASCII files, including three orthogonal X, Y, Z channels and standard vertex-mastoid on the stimulated side. T...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/0169-2607(90)90096-r
更新日期:1990-06-01 00:00:00