Abstract:
:In the last 10 years, resistance in Gram-negative bacteria has been increasing. The present study was designed to evaluate the in vitro antibacterial activities of the methanol extracts of six Cameroonian medicinal plants Albizia adianthifolia, Alchornea laxiflora, Boerhavia diffusa, Combretum hispidum, Laportea ovalifolia and Scoparia dulcis against a panel of 15 multidrug resistant Gram-negative bacterial strains. The broth microdilution was used to determine the minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) of the extracts. The preliminary phytochemical screening of the extracts was conducted according to the reference qualitative phytochemical methods. Results showed that all extracts contained compounds belonging to the classes of polyphenols and triterpenes, other classes of chemicals being selectively distributed. The best antibacterial activities were recorded with bark and root extracts of A. adianthifolia as well as with L. ovalifolia extract, with MIC values ranging from 64 to 1024 μg/mL on 93.3% of the fifteen tested bacteria. The lowest MIC value of 64 μg/mL was recorded with A. laxiflora bark extract against Enterobacter aerogenes EA289. Finally, the results of this study provide evidence of the antibacterial activity of the tested plants and suggest their possible use in the control of multidrug resistant phenotypes.
journal_name
Saudi J Biol Scijournal_title
Saudi journal of biological sciencesauthors
Tchinda CF,Voukeng IK,Beng VP,Kuete Vdoi
10.1016/j.sjbs.2016.01.033subject
Has Abstractpub_date
2017-05-01 00:00:00pages
950-955issue
4eissn
1319-562Xissn
2213-7106pii
S1319-562X(16)00035-8journal_volume
24pub_type
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journal_title:Saudi journal of biological sciences
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journal_title:Saudi journal of biological sciences
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journal_title:Saudi journal of biological sciences
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journal_title:Saudi journal of biological sciences
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journal_title:Saudi journal of biological sciences
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journal_title:Saudi journal of biological sciences
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journal_title:Saudi journal of biological sciences
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journal_title:Saudi journal of biological sciences
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journal_title:Saudi journal of biological sciences
pub_type: 杂志文章
doi:10.1016/j.sjbs.2011.02.004
更新日期:2011-07-01 00:00:00
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journal_title:Saudi journal of biological sciences
pub_type: 杂志文章
doi:10.1016/j.sjbs.2016.09.015
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journal_title:Saudi journal of biological sciences
pub_type: 杂志文章
doi:10.1016/j.sjbs.2015.09.020
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journal_title:Saudi journal of biological sciences
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更新日期:2021-01-01 00:00:00
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journal_title:Saudi journal of biological sciences
pub_type: 杂志文章
doi:10.1016/j.sjbs.2015.07.001
更新日期:2016-09-01 00:00:00
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journal_title:Saudi journal of biological sciences
pub_type: 杂志文章
doi:10.1016/j.sjbs.2016.01.010
更新日期:2017-09-01 00:00:00
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journal_title:Saudi journal of biological sciences
pub_type: 杂志文章
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journal_title:Saudi journal of biological sciences
pub_type: 杂志文章
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更新日期:2014-09-01 00:00:00
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journal_title:Saudi journal of biological sciences
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更新日期:2012-01-01 00:00:00
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journal_title:Saudi journal of biological sciences
pub_type: 杂志文章
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更新日期:2015-01-01 00:00:00
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journal_title:Saudi journal of biological sciences
pub_type: 杂志文章
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journal_title:Saudi journal of biological sciences
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更新日期:2020-01-01 00:00:00
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journal_title:Saudi journal of biological sciences
pub_type: 杂志文章
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更新日期:2017-12-01 00:00:00
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