Effects of verbenalin on prostatitis mouse model.

Abstract:

:The aim of this study was to observe the treatment characteristics of verbenalin on a prostatitis mouse model. Give Xiaozhiling injection in the prostate locally to make a prostatitis mouse model. High, medium and low doses of verbenalin were each given to different mouse groups. The amount of water was determined in 14th, 28th. The number of white cells and lecithin corpuscle density in prostatic fluid were determined. Morphological changes in the prostate, testis, epididymis and kidney were detected. Compared with the model control group, the mice treated with high, medium and low doses of verbenalin had significantly increased amounts of water, and prostate white blood cell count and prostate volume density (Vv) were decreased significantly, the density of lecithin corpuscle score increased, and pathologic prostatitis changes were significantly reduced. Pathological change in the testis was significantly reduced and the change in the epididymis was obviously reduced. The thymic cortex thickness and the number of lymphocytes increased significantly and could reduce the renal pathological changes in potential. Verbenalin has a good therapeutic effect on the prostatitis mouse model.

journal_name

Saudi J Biol Sci

authors

Miao M,Guo L,Yan X,Wang T,Li Z

doi

10.1016/j.sjbs.2015.10.006

subject

Has Abstract

pub_date

2016-01-01 00:00:00

pages

S148-57

issue

1

eissn

1319-562X

issn

2213-7106

pii

S1319-562X(15)00247-8

journal_volume

23

pub_type

杂志文章
  • In vitro alpha-amylase inhibition and in vivo antioxidant potential of Momordica dioica seeds in streptozotocin-induced oxidative stress in diabetic rats.

    abstract::Momordica dioica Roxb. Commonly known as "Kakora" in Telugu, is used in the Indian traditional system of medicine for the treatment of diabetes. The aim of this study was to investigate the antidiabetic activity of methanolic extract of M. dioica seeds (MEMD) in streptozotocin (STZ) induced diabetic rats. The in vitro...

    journal_title:Saudi journal of biological sciences

    pub_type: 杂志文章

    doi:10.1016/j.sjbs.2016.01.010

    authors: Rao PS,Mohan GK

    更新日期:2017-09-01 00:00:00

  • Antibiogram and phylogenetic diversity of enterotoxigenic Staphylococcus aureus strains from milk products and public health implications.

    abstract::Food poisoning caused by Staphylococcus aureus (S. aureus) toxins is considered one of the foremost public health threat that usually occurs through the ingestion of raw milk contaminated with staphylococcal enterotoxins. The current study spotlights on the prevalence, antibiogram and genetic diversity of S. aureus en...

    journal_title:Saudi journal of biological sciences

    pub_type: 杂志文章

    doi:10.1016/j.sjbs.2020.06.028

    authors: Abdeen EE,Mousa WS,Abdel Salam SY,Al-Maary KS,Mubarak AS,Moussa IM,Hemeg HA,Almuzaini AM,Alajaji AI,Alsubki RA,Elbehiry A

    更新日期:2020-08-01 00:00:00

  • An in vitro study of Ocimum sanctum as a chemotherapeutic agent on oral cancer cell-line.

    abstract::Oral squamous cell carcinoma (OSCC) is the most commom cancer in the world. If remain untreated for several years, it may be fatal. Hence, it is important to prevent and treat OSCC at an early stage. In this study the effect of aqueous and dry leaves extract of Ocimum sanctum was observed on Ca9-22 cell line, which is...

    journal_title:Saudi journal of biological sciences

    pub_type: 杂志文章

    doi:10.1016/j.sjbs.2020.11.030

    authors: Luke AM,Patnaik R,Kuriadom ST,Jaber M,Mathew S

    更新日期:2021-01-01 00:00:00

  • Histological and histochemical alterations in the liver induced by lead chronic toxicity.

    abstract::Adult males of the Wistar albino rats (Rattus norvegicus) were exposed to lead acetate trihydrate in drinking water (0.0%, 0.25%, 0.5%, 1% and 2% for 1-12 months) to investigate histological and histochemical alterations induced by lead intoxication in the liver. Chronic exposure to subtoxic concentrations of lead pro...

    journal_title:Saudi journal of biological sciences

    pub_type: 杂志文章

    doi:10.1016/j.sjbs.2011.12.005

    authors: Jarrar BM,Taib NT

    更新日期:2012-04-01 00:00:00

  • Effect of artemisinin on proliferation and apoptosis-related protein expression in vivo and in vitro.

    abstract::Artemisinin is the first-line drugs for the treatment of malaria. In recent years, a large number of reports showed that artemisinin exhibit anti-tumor activity. In this study, we used C6 glioma cells and rat C6 brain-glioma model to study anti-tumor activity of artemisinin in vivo and in vitro. We found that artemisi...

    journal_title:Saudi journal of biological sciences

    pub_type: 杂志文章

    doi:10.1016/j.sjbs.2018.04.003

    authors: Chen J,Zhang L,Hao M

    更新日期:2018-11-01 00:00:00

  • Diversity of purple nonsulfur bacteria in shrimp ponds with varying mercury levels.

    abstract::This research aimed to study the diversity of purple nonsulfur bacteria (PNSB) and to investigate the effect of Hg concentrations in shrimp ponds on PNSB diversity. Amplification of the pufM gene was detected in 13 and 10 samples of water and sediment collected from 16 shrimp ponds in Southern Thailand. In addition to...

    journal_title:Saudi journal of biological sciences

    pub_type: 杂志文章

    doi:10.1016/j.sjbs.2015.05.014

    authors: Mukkata K,Kantachote D,Wittayaweerasak B,Techkarnjanaruk S,Boonapatcharoen N

    更新日期:2016-07-01 00:00:00

  • Cytogenotoxic effects of Adenium obesum seeds extracts on breast cancer cells.

    abstract::The extracts prepared from various areal parts of the Adenium obesum (Forssk.) Roem. & Schult. (Family: Apocynaceae) including leaves, fruit and seeds ethanolic extracts and seed aqueous extract were evaluated against MCF-7 cells in order to investigate its potential of cytogenotoxicity and induction of apoptosis. The...

    journal_title:Saudi journal of biological sciences

    pub_type: 杂志文章

    doi:10.1016/j.sjbs.2018.12.014

    authors: Ali AQ,Farah MA,Abou-Tarboush FM,Al-Anazi KM,Ali MA,Lee J,Hailan WAQ,Mahmoud AH

    更新日期:2019-03-01 00:00:00

  • The extraction of different proteins in selenium enriched peanuts and their antioxidant properties.

    abstract::In this study, the selenium enriched peanuts and the different solubility proteins extracted from them were investigated. The dried defatted selenium enriched peanuts (SeP) powder (0.3147 μg/g) had a 2.5-fold higher mean total selenium concentration than general peanuts (GP) power (0.1233 μg/g). The SeP had higher con...

    journal_title:Saudi journal of biological sciences

    pub_type: 杂志文章

    doi:10.1016/j.sjbs.2015.08.007

    authors: Zhao P,Wang Y,Zhang Y,Guo T,Zhang Z,Zhang WJ,Zhang XG,Ashraf MA

    更新日期:2016-05-01 00:00:00

  • Impact of bio-fertilizers and different levels of cadmium on the growth, biochemical contents and lipid peroxidation of Plantago ovata Forsk.

    abstract::Plantago ovata Forsk. (isabgol) is a valuable medicinal plant; its seeds and shell have a significant role in pharmacy as a laxative compound. Increasing soil contamination with cadmium (Cd) is one of the major concerns and is responsible for toxic effects in plants. This investigation was aimed to analyze the role of...

    journal_title:Saudi journal of biological sciences

    pub_type: 杂志文章

    doi:10.1016/j.sjbs.2013.12.005

    authors: Haneef I,Faizan S,Perveen R,Kausar S

    更新日期:2014-09-01 00:00:00

  • Molecular and serotyping characterization of shiga toxogenic Escherichia coli associated with food collected from Saudi Arabia.

    abstract::Shiga toxin-producing Escherichia coli (STEC) strains are considered as one of the major food-borne disease agents in humans worldwide. STEC strains, also called verotoxin-producing E. coli strains. The objectives of the present study were serotyping and molecular characterization of shiga toxigenic E. coli associated...

    journal_title:Saudi journal of biological sciences

    pub_type: 杂志文章

    doi:10.1016/j.sjbs.2015.02.019

    authors: Al-Zogibi OG,Mohamed MI,Hessain AM,El-Jakee JK,Kabli SA

    更新日期:2015-07-01 00:00:00

  • A review on ethno-medicinal plants used in traditional medicine in the Kingdom of Saudi Arabia.

    abstract::The traditional medicine based on medicinal plants in the Kingdom of Arabia Saudia presents a strong relationship belonging to natural remedies, health, diet, and folk healing practice recognized by a specific culture. The aim of the current study is to carry out an ethnobotanical review on medicinal plants used in tr...

    journal_title:Saudi journal of biological sciences

    pub_type: 杂志文章,评审

    doi:10.1016/j.sjbs.2020.06.020

    authors: Ullah R,Alqahtani AS,Noman OMA,Alqahtani AM,Ibenmoussa S,Bourhia M

    更新日期:2020-10-01 00:00:00

  • Research of population with impulsive perturbations based on dynamics of a neutral delay equation and ecological quality system.

    abstract::This paper studies the global behaviors of a nonlinear autonomous neutral delay differential population model with impulsive perturbation. This model may be suitable for describing the dynamics of population with long larval and short adult phases. It is shown that the system may have global stability of the extinctio...

    journal_title:Saudi journal of biological sciences

    pub_type: 杂志文章

    doi:10.1016/j.sjbs.2015.10.018

    authors: Xiong W,Jiang H

    更新日期:2016-01-01 00:00:00

  • Nests of Marsh harrier (Circus aeruginosus L.) as refuges of potentially phytopathogenic and zoopathogenic fungi.

    abstract::Birds' nests may be refuges for various species of fungi including that which are potentially phytopathogenic and zoopathogenic. Among the 2449 isolates of fungi obtained from nests of Marsh harriers 96.8% belonged to filamentous fungi. In total, 37 genera were identified from 63 fungi species. Within the mycobiotas o...

    journal_title:Saudi journal of biological sciences

    pub_type: 杂志文章

    doi:10.1016/j.sjbs.2017.03.016

    authors: Kornillowicz-Kowalska T,Kitowski I

    更新日期:2018-01-01 00:00:00

  • Effects of Melothria maderaspatana leaf extract on antioxidant status in sham-operated and uninephrectomized DOCA-salt hypertensive rats.

    abstract::The present study was designed to investigate the antihypertensive and antioxidant effect of Melothria maderaspatana leaf extract (MME) on sham-operated and DOCA-salt (deoxycorticosterone acetate) induced hypertensive rats. Administration of DOCA-salt significantly increased the systolic (from 127 to 212 mm Hg) and di...

    journal_title:Saudi journal of biological sciences

    pub_type: 杂志文章

    doi:10.1016/j.sjbs.2010.05.002

    authors: Veeramani C,Aristatile B,Pushpavalli G,Pugalendi KV

    更新日期:2011-01-01 00:00:00

  • Effectiveness of five antidandruff cosmetic formulations against planktonic cells and biofilms of dermatophytes.

    abstract::This study aimed to investigate the in vitro antifungal effectiveness of five different formulations against dandruff and ringworm dermatophytes. Candida albicans was also included in our assays. Fungal susceptibility tests were performed with planktonic cells and biofilms of reference strains. Microbiological and phy...

    journal_title:Saudi journal of biological sciences

    pub_type: 杂志文章

    doi:10.1016/j.sjbs.2015.09.033

    authors: Dos Santos RM,Dias-Souza MV

    更新日期:2017-02-01 00:00:00

  • A report on the association of influenza B virus with respiratory tract infection of hospitalized children in Saudi Arabia.

    abstract::Influenza viruses are recognized as one of the major causes of respiratory tract infection in young children and elderly people throughout the world. In this report, influenza B virus was detected when 200 clinical samples of nasopharyngeal aspirates, collected from hospitalized children aged from one month to three y...

    journal_title:Saudi journal of biological sciences

    pub_type: 杂志文章

    doi:10.1016/j.sjbs.2009.10.008

    authors: Almajhdi FN

    更新日期:2009-10-01 00:00:00

  • Influence of bone mineral density in circulating adipokines among postmenopausal Arab women.

    abstract::Osteoporosis and osteopenia has a significant link with substantial fracture risk. Epidemiological data revealed a protective role of adipose tissue on bone biology in postmenopausal osteoporosis. The current study assessed the associations between select adipokines and bone mineral density (BMD) in postmenopausal wom...

    journal_title:Saudi journal of biological sciences

    pub_type: 杂志文章

    doi:10.1016/j.sjbs.2019.10.007

    authors: Ansari MGA,Hussain SD,Wani KA,Yakout SM,Al-Disi D,Alokail MS,Reginster JY,Al-Daghri NM

    更新日期:2020-01-01 00:00:00

  • Antifibrotic effects of crocin on thioacetamide-induced liver fibrosis in mice.

    abstract::Liver fibrosis is a major health concern that results in significant morbidity and mortality. Up-to-date, there is no standard treatment for fibrosis because of its complex pathogenesis. Crocin is one of the main nutraceuticals isolated from the stigma of Crocus sativus with antioxidant and anti-inflammatory activitie...

    journal_title:Saudi journal of biological sciences

    pub_type: 杂志文章

    doi:10.1016/j.sjbs.2016.10.007

    authors: Algandaby MM

    更新日期:2018-05-01 00:00:00

  • In vitro biocontrol activity of halotolerant Streptomyces aureofaciens K20: A potent antagonist against Macrophomina phaseolina (Tassi) Goid.

    abstract::A halotolerant actinobacterial strain isolated from salinity affected soil of Eastern Indo-Gangetic plains (IGP), Uttar Pradesh, India, was characterised for its antagonistic potential against Macrophomina phaseolina by dual-culture assay. It was shown to effectively inhibit the growth of M. phaseolina with an inhibit...

    journal_title:Saudi journal of biological sciences

    pub_type: 杂志文章

    doi:10.1016/j.sjbs.2015.12.004

    authors: Shrivastava P,Kumar R,Yandigeri MS

    更新日期:2017-01-01 00:00:00

  • Antibacterial substances from marine algae isolated from Jeddah coast of Red sea, Saudi Arabia.

    abstract::Marine algae are known to produce a wide variety of bioactive secondary metabolites and several compounds have been derived from them for prospective development of novel drugs by the pharmaceutical industries. However algae of the Red sea have not been adequately explored for their potential as a source of bioactive ...

    journal_title:Saudi journal of biological sciences

    pub_type: 杂志文章

    doi:10.1016/j.sjbs.2013.06.001

    authors: Al-Saif SS,Abdel-Raouf N,El-Wazanani HA,Aref IA

    更新日期:2014-01-01 00:00:00

  • The expression of macrophage migration inhibitory factor in the non-small cell lung cancer.

    abstract:Objective:The objective was to investigate the expression of macrophage migration inhibitory factor (MIF) in non-small cell lung cancer (NSCLC), as well as the effects of macrophage MIF on tumor cells. Methods:The human NSCLC cell strains H358 and H524 were selected as research objects. The Real-Time Polymerase Chain ...

    journal_title:Saudi journal of biological sciences

    pub_type: 杂志文章

    doi:10.1016/j.sjbs.2020.04.027

    authors: Zhang H,Duan J,Wu O

    更新日期:2020-06-01 00:00:00

  • Changes of nutritional status and the variations of serum indicators of patients with chronic kidney disease accompanied by hypothyroidism taking thyroid hormone replacement therapy as the therapeutic models.

    abstract::This study aimed to analyze the incidence of malnutrition in patients with chronic kidney disease (CKD) at stage III-IV accompanied by hypothyroidism and indicate the improvement in nutritional status and kidney disease of CKD patients after undergoing thyroid hormone replacement (THR) therapy as therapeutic models. T...

    journal_title:Saudi journal of biological sciences

    pub_type: 杂志文章

    doi:10.1016/j.sjbs.2019.09.023

    authors: Deng X,Tang C,Wu J,Han R,Fang F

    更新日期:2019-12-01 00:00:00

  • Chemical compositions and characteristics of organic compounds in propolis from Yemen.

    abstract::Propolis is a gummy material made by honeybees for protecting their hives from bacteria and fungi. The main objective of this study is to determine the chemical compositions and concentrations of organic compounds in the extractable organic matter (EOM) of propolis samples collected from four different regions in Yeme...

    journal_title:Saudi journal of biological sciences

    pub_type: 杂志文章

    doi:10.1016/j.sjbs.2016.12.012

    authors: Al-Ghamdi AA,Bayaqoob NIM,Rushdi AI,Alattal Y,Simoneit BRT,El-Mubarak AH,Al-Mutlaq KF

    更新日期:2017-07-01 00:00:00

  • Alleviation of cadmium stress in Solanum lycopersicum L. by arbuscular mycorrhizal fungi via induction of acquired systemic tolerance.

    abstract::Experiments were conducted to evaluate cadmium (Cd) stress-induced changes in growth, antioxidants and lipid composition of Solanum lycopersicum with and without arbuscular mycorrhizal fungi (AMF). Cadmium stress (50 μM) caused significant changes in the growth and physio-biochemical attributes studied. AMF mitigated ...

    journal_title:Saudi journal of biological sciences

    pub_type: 杂志文章

    doi:10.1016/j.sjbs.2015.11.002

    authors: Hashem A,Abd Allah EF,Alqarawi AA,Al Huqail AA,Egamberdieva D,Wirth S

    更新日期:2016-03-01 00:00:00

  • Demographic structure and stock status of Lethrinus lentjan in Saudi coastal waters of the Red Sea.

    abstract::Fishes of the family Lethrinidae form a considerable portion of the catch from both the Red Sea and the Arabian Gulf in Saudi Arabia, and the species Lethrinus lentjan (Lacepède, 1802) is one of the most important among these fishes. This study was conducted to evaluate the demographic structure coefficients, survival...

    journal_title:Saudi journal of biological sciences

    pub_type: 杂志文章

    doi:10.1016/j.sjbs.2020.06.003

    authors: Younis EM,Abdel-Warith AA,Al-Asgah NA,Gabr MH,Shamlol FS

    更新日期:2020-09-01 00:00:00

  • Inhibition of autophagy of Cajal mesenchymal cells by gavage of tong bian decoction based on the rat model of chronic transit constipation.

    abstract::The objective of this research was to study the effect of tong bian decoction on colon transport function of interstitial cells of Cajal (ICC) in chronic transit constipation (CTC) and the inhibition of autophagy of ICC, so as to achieve the free movement of the bowels. In this research, the experimental rats were div...

    journal_title:Saudi journal of biological sciences

    pub_type: 杂志文章

    doi:10.1016/j.sjbs.2019.11.040

    authors: Zhou X,Qian H,Zhang D,Zeng L

    更新日期:2020-02-01 00:00:00

  • Influence of premolar extraction or non-extraction orthodontic therapy on the angular changes of mandibular third molars.

    abstract:AIM:To compare the angular changes of the third molars relative to the occlusal plane and to the second molar long axis in extraction group and compare these changes with a non extraction group. MATERIALS AND METHODS:The study included pre and post treatment panoramic radiograph records of 90 subjects treated by first...

    journal_title:Saudi journal of biological sciences

    pub_type: 杂志文章

    doi:10.1016/j.sjbs.2016.02.006

    authors: Durgesh BH,Gowda KH,AlShahrani OA,Almalki AD,Almalki WD,Balharith MM,Motashesh NY,Alkheraif AA,Hashem MI

    更新日期:2016-11-01 00:00:00

  • Alkaline phosphatase and acid phosphatase levels in saliva and serum of patients with healthy periodontium, gingivitis, and periodontitis before and after scaling with root planing: A clinico-biochemical study.

    abstract::Periodontitis is commonly diagnosed based on clinical parameters. However, the analysis of a few unique biomarkers of the disease process present in the saliva and blood can further assist the estimation of the rate of disease progression. Aim:The present study attempted to correlate the alkaline phosphatase (ALP) an...

    journal_title:Saudi journal of biological sciences

    pub_type: 杂志文章

    doi:10.1016/j.sjbs.2020.10.016

    authors: Koppolu P,Sirisha S,Mishra A,Deshpande K,Lingam AS,Alotaibi DH,Saleh Alwahibi M,Penela S

    更新日期:2021-01-01 00:00:00

  • Morphological characteristics of worm lizard, Diplometopon zarudnyi (Squamata: Trogonophidae), in the central region of Saudi Arabia.

    abstract::We report morphometric data for 133 specimens of Diplometopon zarudnyi (Squamata: Trogonophidae) collected across its range within Riyadh province of Saudi Arabia. One-way analyses of variance revealed that differences exist in most characters. Snout-vent length and vent-tail length showed slight and inconsistent diff...

    journal_title:Saudi journal of biological sciences

    pub_type: 杂志文章

    doi:10.1016/j.sjbs.2016.12.003

    authors: Rudayni HA,Al-Sadoon MK,Paray BA

    更新日期:2017-05-01 00:00:00

  • Biosynthesis of silver nanoparticles by using of the marine brown alga Padina pavonia and their characterization.

    abstract::Silver nanoparticles (AgNPs) are gaining considerable importance due to their attractive physicochemical properties for many applications. In the present study, (Ag NPs) were synthesized by the reduction of aqueous solutions of silver nitrate (AgNO3) with powder and solvent extracts of Padina pavonia (brown algae). Th...

    journal_title:Saudi journal of biological sciences

    pub_type: 杂志文章

    doi:10.1016/j.sjbs.2018.01.007

    authors: Abdel-Raouf N,Al-Enazi NM,Ibraheem IBM,Alharbi RM,Alkhulaifi MM

    更新日期:2019-09-01 00:00:00