当前位置： SCI文献检索 > SAUDI JOURNAL OF BIOLOGICAL SCIENCES期刊下所有文献 > Effect of artemisinin on proliferation and apoptosis-related protein expression in vivo and in vitro.

Effect of artemisinin on proliferation and apoptosis-related protein expression in vivo and in vitro.

Abstract：

:Artemisinin is the first-line drugs for the treatment of malaria. In recent years, a large number of reports showed that artemisinin exhibit anti-tumor activity. In this study, we used C6 glioma cells and rat C6 brain-glioma model to study anti-tumor activity of artemisinin in vivo and in vitro. We found that artemisinin inhibited the proliferation in C6 cells and induced cell cycle arrest and a caspase-3-dependent cell apoptosis. It also inhibited the growth of C6 brain-glioma in vivo and enhanced living state of rat brain-glioma model. These results suggested that artemisinin had significant anti-tumor activities on C6 cells both in vitro and in vivo. Artemisinin might be exploited as a promising clinical anti-cancer drug in future.

journal_name

Saudi J Biol Sci

journal_title

Saudi journal of biological sciences

authors

Chen J,Zhang L,Hao M

doi

10.1016/j.sjbs.2018.04.003

subject

Has Abstract

pub_date

2018-11-01 00:00:00

pages

1488-1493

issue

7

eissn

1319-562X

issn

2213-7106

pii

S1319-562X(18)30086-X

journal_volume

25

pub_type

杂志文章

相关文献

SAUDI JOURNAL OF BIOLOGICAL SCIENCES文献大全
  • Cytogenotoxic effects of Adenium obesum seeds extracts on breast cancer cells.

    abstract：:The extracts prepared from various areal parts of the Adenium obesum (Forssk.) Roem. & Schult. (Family: Apocynaceae) including leaves, fruit and seeds ethanolic extracts and seed aqueous extract were evaluated against MCF-7 cells in order to investigate its potential of cytogenotoxicity and induction of apoptosis. The...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2018.12.014

    authors： Ali AQ,Farah MA,Abou-Tarboush FM,Al-Anazi KM,Ali MA,Lee J,Hailan WAQ,Mahmoud AH

    更新日期：2019-03-01 00:00:00

  • Free radical scavenging activity, total phenolic content, total antioxidant status, and total oxidant status of endemic Thermopsis turcica.

    abstract：:Thermopsis turcica, endemic to Turkey, is in danger of extinction. Studies on this species are very few due to the fact that it was only discovered in 1983 and grows in a small circumscribed area in Turkey. In this study, free radical scavenging activity, total phenolic content, total oxidant status (TOS), and total a...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2013.02.003

    authors： Aksoy L,Kolay E,Ağılönü Y,Aslan Z,Kargıoğlu M

    更新日期：2013-07-01 00:00:00

  • Prediction of complex super-secondary structure βαβ motifs based on combined features.

    abstract：:Prediction of a complex super-secondary structure is a key step in the study of tertiary structures of proteins. The strand-loop-helix-loop-strand (βαβ) motif is an important complex super-secondary structure in proteins. Many functional sites and active sites often occur in polypeptides of βαβ motifs. Therefore, the ...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2015.10.005

    authors： Sun L,Hu X,Li S,Jiang Z,Li K

    更新日期：2016-01-01 00:00:00

  • Assessing risks of pesticides targeting lepidopteran pests in cruciferous ecosystems to eggs parasitoid, Trichogramma brassicae (Bezdenko).

    abstract：:Lethal and sub lethal effects of fresh and old residues of azadirachtin, spinosad, Bacillus thuringiensis var. kurstaki (Bt var. k), and deltamethrin, were evaluated at their recommended field doses against adult and immature stages of Trichogramma brassicae under in vitro conditions. The experiments were carried out ...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2016.04.007

    authors： Thubru DP,Firake DM,Behere GT

    更新日期：2018-05-01 00:00:00

  • Legume genomics and transcriptomics: From classic breeding to modern technologies.

    abstract：:Legumes are essential and play a significant role in maintaining food standards and augmenting physiochemical soil properties through the biological nitrogen fixation process. Biotic and abiotic factors are the main factors limiting legume production. Classical breeding methodologies have been explored extensively abo...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章,评审

    doi：10.1016/j.sjbs.2019.11.018

    authors： Afzal M,Alghamdi SS,Migdadi HH,Khan MA,Nurmansyah,Mirza SB,El-Harty E

    更新日期：2020-01-01 00:00:00

  • A review on ethno-medicinal plants used in traditional medicine in the Kingdom of Saudi Arabia.

    abstract：:The traditional medicine based on medicinal plants in the Kingdom of Arabia Saudia presents a strong relationship belonging to natural remedies, health, diet, and folk healing practice recognized by a specific culture. The aim of the current study is to carry out an ethnobotanical review on medicinal plants used in tr...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章,评审

    doi：10.1016/j.sjbs.2020.06.020

    authors： Ullah R,Alqahtani AS,Noman OMA,Alqahtani AM,Ibenmoussa S,Bourhia M

    更新日期：2020-10-01 00:00:00

  • Neurophysiological study on possible protective and therapeutic effects of Sidr (Zizyphus spina-christi L.) leaf extract in male albino rats treated with pentylenetetrazol.

    abstract：:In this study, anti-convulsant effect of Sidr leaf extract was examined by using pentylenetetrazol (PTZ) model on male albino rat by evaluating the changes in norepinephrine (NE), dopamine (DA) and serotonin (5-HT) contents in different brain regions (cerebellum, brainstem, striatum, cerebral cortex, hypothalamus and ...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2010.05.003

    authors： Waggas AM,Al-Hasani RH

    更新日期：2010-10-01 00:00:00

  • In vitro biological properties of Streptomyces cangkringensis isolated from the floral rhizosphere regions.

    abstract：:This context was investigated to determine in vitro antimicrobial, antioxidative, and anticancer traits of crude ethyl acetate extract of Streptomyces cangkringensis strain TSAS 04 isolated from soil sample of rhizosphere regions. The antimicrobial activity of ethyl acetate extract of strain TSAS 04 was determined aga...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2020.09.035

    authors： Saraswathi K,Mahalakshmi S,Khusro A,Arumugam P,Khaloud Mohammed A,Alkufeidy RM

    更新日期：2020-12-01 00:00:00

  • Self-medication and antibiotic resistance: Crisis, current challenges, and prevention.

    abstract：:The present study aims to explore the crisis of antibiotic resistance and discover more about the current challenges related to self-medication. The current challenges related to antibiotic resistance are unique and differ from the challenges of the past since new bacterial pathogens are involved and continue to evolv...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章,评审

    doi：10.1016/j.sjbs.2017.01.004

    authors： Rather IA,Kim BC,Bajpai VK,Park YH

    更新日期：2017-05-01 00:00:00

  • Bioinformatics analysis of ubiquitin expression protein gene from Heterodera latipons.

    abstract：:Ubiquitin expression protein DNA clone (Hl-UBI) was isolated from Heterodera latipons collected from North Jordan. Its sequence of 285 nucleotides was also determined and deposited in the GeneBank. The 285-bp open reading frame coded for 76-amino acid protein having two domains; the ubiquitin domain and the C terminal...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2018.06.005

    authors： Al-Banna L,Sadder MT,Lafi HA,Dawabah AAM,Al-Nadhari SN

    更新日期：2019-11-01 00:00:00

  • Impact of raking and baling patterns on alfalfa hay dry matter and quality losses.

    abstract：:A field study was conducted to investigate the impact of different patterns of raking and baling operations on the dry matter (DM) and quality losses of the produced alfalfa (Medicago sativa) hay. The experimental work was carried out on a 50 ha center pivot irrigated alfalfa field in a commercial farm located in the ...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2018.02.009

    authors： Al-Gaadi KA

    更新日期：2018-09-01 00:00:00

  • Impact of bio-fertilizers and different levels of cadmium on the growth, biochemical contents and lipid peroxidation of Plantago ovata Forsk.

    abstract：:Plantago ovata Forsk. (isabgol) is a valuable medicinal plant; its seeds and shell have a significant role in pharmacy as a laxative compound. Increasing soil contamination with cadmium (Cd) is one of the major concerns and is responsible for toxic effects in plants. This investigation was aimed to analyze the role of...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2013.12.005

    authors： Haneef I,Faizan S,Perveen R,Kausar S

    更新日期：2014-09-01 00:00:00

  • Reverse transcription loop-mediated isothermal amplification to rapidly detect Rice ragged stunt virus.

    abstract：:Rice ragged stunt virus (RRSV) is a very important virus that infects rice and causes serious yield losses in Asian countries and other major rice planting areas. Thus, it is urgent to establish an efficient and practical approach for identification and diagnosis in the field. Our results indicated that reverse transc...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2016.02.024

    authors： Lai D,Zhang Y,Huang Q,Yin G,Pennerman KK,Liu Z,Guo A

    更新日期：2018-12-01 00:00:00

  • Evaluation of edible mushroom Oudemansiella canarii cultivation on different lignocellulosic substrates.

    abstract：:In this study, the mycelial growth rate, mycelial colonization time, yield, and biological efficiency of the edible mushroom Oudemansiella canarii were determined, and the effects of different substrate combinations on productivity, chemical contents and amino acids were evaluated. Lignocellulosic wastes, such as cott...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2015.07.001

    authors： Xu F,Li Z,Liu Y,Rong C,Wang S

    更新日期：2016-09-01 00:00:00

  • D-Pinitol treatment induced the apoptosis in human leukemia MOLT-4 cells by improved apoptotic signaling pathway.

    abstract：:Cancer is still remain as a global burden with the 18.1 million and 9.6 million new cases and mortlities, respectively estimated globally. Leukemia may arise at all ages varied from the infants to elders. In this exploration, we planned to evaluate the antiproliferative effect of D-pinitol on human leukemia MOLT-4 cel...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2020.06.034

    authors： Yao X,Shi K,Yang Y,Gu X,Tan W,Wang Q,Gao X,Priya Veeraraghavan V,Mohan SK,Jin S

    更新日期：2020-08-01 00:00:00

  • Bioaccumulation of lead nitrate in tissues and its effects on hematological and biochemical parameters of Clarias gariepinus.

    abstract：:Clarias gariepinus, weighing 119.18 ± 5.21 g, were exposed to 0%, 20%, 40%, and 60% of the LC50 lead nitrate, Pb(NO3)2, which represents the following treatments 0 (control), 16, 32, and 48 mg/l, respectively, for a period of 10 and 20 days. The results showed that the bioaccumulation of Pb(NO3)2 in gills were signifi...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2020.01.015

    authors： Abdel-Warith AA,Younis EMI,Al-Asgah NA,Rady AM,Allam HY

    更新日期：2020-03-01 00:00:00

  • Bacillus subtilis: A plant-growth promoting rhizobacterium that also impacts biotic stress.

    abstract：:Plants encounter many biotic agents, such as viruses, bacteria, nematodes, weeds, and arachnids. These entities induce biotic stress in their hosts by disrupting normal metabolism, and as a result, limit plant growth and/or are the cause of plant mortality. Some biotic agents, however, interact symbiotically or synerg...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章,评审

    doi：10.1016/j.sjbs.2019.05.004

    authors： Hashem A,Tabassum B,Fathi Abd Allah E

    更新日期：2019-09-01 00:00:00

  • Chemical signals and their regulations on the plant growth and water use efficiency of cotton seedlings under partial root-zone drying and different nitrogen applications.

    abstract：:Partial root-zone drying during irrigation (PRD) has been shown effective in enhancing plant water use efficiency (WUE), however, the roles of chemical signals from root and shoot that are involved and the possible interactions affected by nitrogen nutrition are not clear. Pot-grown cotton (Gossypium spp.) seedlings w...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2017.01.015

    authors： Li W,Jia L,Wang L

    更新日期：2017-03-01 00:00:00

  • Effect of chlorpyrifos on healing of cutaneous leishmaniasis lesions after treatment with Pentostam(®).

    abstract：:The insecticide chlorpyrifos (CPF) is widely used in the Kingdom of Saudi Arabia (KSA) to control agricultural pests. The present work is a preliminary investigation of the effect of CPF on healing of cutaneous leishmaniasis (CL) lesions, caused by Leishmania major in farmers exposed to this insecticide, after treatme...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2009.07.005

    authors： Al-Dawood AN,Al-Ghazal RA,Al-Jaser MH,Khalil GM

    更新日期：2009-07-01 00:00:00

  • Methicillin-resistant Staphylococcus aureus (MRSA) screening of hospital dental clinic surfaces.

    abstract：:We assessed the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) strains on surfaces of hospital dental clinics. Specimens were obtained from 5 clinically symptoms-free patients of five different specialties clinics (Implantology, Pediatric Dentistry, Prosthetics, Restorative Dentistry, and Oral Medici...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2018.03.006

    authors： Faden A

    更新日期：2019-11-01 00:00:00

  • Interaction between Meloidogyne incognita and Rhizoctonia solani on green beans.

    abstract：:The interaction between Meloidogyne incognita (race 2) and Rhizoctonia solani (AG 4) in a root rot disease complex of green beans (Phaseolus vulgaris) was examined in a greenhouse pot experiment. Three week-old seedlings (cv. Contender) were inoculated with the nematode and/or the fungus in different combinations and ...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2015.04.008

    authors： Al-Hazmi AS,Al-Nadary SN

    更新日期：2015-09-01 00:00:00

  • Molecular cloning and characterization of rosmarinic acid biosynthetic genes and rosmarinic acid accumulation in Ocimum basilicum L.

    abstract：:We have aimed to investigate the expression of genes related to rosmarinic acid (RA) synthesis and rosmarinic acid content in 2 Ocimum basilicum cultivars, green (cinnamon) and purple (red rubin) basil. Specifically, genes related to rosmarinic acid biosynthesis were cloned and characterized for O. basilicum. We obtai...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2017.03.010

    authors： Kwon DY,Li X,Kim JK,Park SU

    更新日期：2019-03-01 00:00:00

  • Responses of Corpuscles of Stannius to intra-peritoneal vitamin-D3 administration in teleost Labeo rohita (Hamilton, 1822) reared in water with two different levels of calcium concentration.

    abstract：:This study assessed the responses of vitamin-D3 intraperitoneally injected to Rohu, Labeo rohita @ of 0 IU/kg bw (only solvent), 100 IU/kg bw and 500 IU/kg bw reared in 20 and 40 ppm of calcium (Ca) enriched water. The cellular changes in Corpuscles of Stannius (CS) gland, serum Ca, and inorganic phosphate (Pi) level ...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2020.07.033

    authors： Sivagurunathan U,Srivastava PP,Gupta S,Krishna G

    更新日期：2020-12-01 00:00:00

  • Antibiogram and phylogenetic diversity of enterotoxigenic Staphylococcus aureus strains from milk products and public health implications.

    abstract：:Food poisoning caused by Staphylococcus aureus (S. aureus) toxins is considered one of the foremost public health threat that usually occurs through the ingestion of raw milk contaminated with staphylococcal enterotoxins. The current study spotlights on the prevalence, antibiogram and genetic diversity of S. aureus en...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2020.06.028

    authors： Abdeen EE,Mousa WS,Abdel Salam SY,Al-Maary KS,Mubarak AS,Moussa IM,Hemeg HA,Almuzaini AM,Alajaji AI,Alsubki RA,Elbehiry A

    更新日期：2020-08-01 00:00:00

  • Influence of inoculation with plant growth promoting rhizobacteria (PGPR) on tomato plant growth and nematode reproduction under greenhouse conditions.

    abstract：:Numerous species of soil bacteria which flourish in the rhizosphere of plants or around plant tissues stimulate plant growth and reduce nematode population by antagonistic behavior. These bacteria are collectively known as PGPR (plant growth promoting rhizobacteria). The effects of six isolates of PGPR Pseudomonas put...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2012.10.004

    authors： Almaghrabi OA,Massoud SI,Abdelmoneim TS

    更新日期：2013-01-01 00:00:00

  • Anatomy and physiology of a scientific paper.

    abstract：:Writing and publishing a scientific paper in academic journals is a highly competitive, time-consuming stepwise process. The road to scientific writing and publication is rarely straightforward. Scientific writing has uniform format, which is perplexing for the novice science writers due to its inflexible anatomy (str...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章,评审

    doi：10.1016/j.sjbs.2018.01.004

    authors： Meo SA

    更新日期：2018-11-01 00:00:00

  • Conservation in Saudi Arabia; moving from strategy to practice.

    abstract：:Conservation in the Kingdom of Saudi Arabia is relatively young, yet have made considerable gains in conservation through strategic proclamation and reintroductions. Changes in land use, illegal hunting and competition with domestic stock has decimated the native ungulates, meaning that the survival of the native ungu...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2017.03.009

    authors： Barichievy C,Sheldon R,Wacher T,Llewellyn O,Al-Mutairy M,Alagaili A

    更新日期：2018-02-01 00:00:00

  • Covid-19 pandemic outburst in Saudi Arabia: A glimpse.

    abstract：:Severe Acute Respiratory Syndrome Coronavirus2 (SARS-CoV2) provoked alertness globally. Existing pandemic eruption of infections with SARS-CoV2 has been phrased as coronavirus disease 2019 (covid-19). Worldwide pneumonia outburst attributable to new SARS-CoV2 alleged to be originated in Wuhan city of China and has aff...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章,评审

    doi：10.1016/j.sjbs.2020.07.026

    authors： Ameen F,Amna T,Alghamdi AAA,AlKahtani MDF,AlYahya SA

    更新日期：2020-12-01 00:00:00

  • Prevalence and molecular characteristics of sequence type 131 clone among clinical uropathogenic Escherichia coli isolates in Riyadh, Saudi Arabia.

    abstract：Background:The antimicrobial resistance of extraintestinal pathogenic Escherichia coli (ExPEC) has progressively been reported worldwide. This resistance has been ascribed to global dissemination of a single E. coli clone, namely E. coli sequence type 131 (E. coli ST131). The main goal of this study is to determine the...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2019.09.020

    authors： Alqasim A,Abu Jaffal A,Alyousef AA

    更新日期：2020-01-01 00:00:00

  • Impact of lactation stage on milk composition and blood biochemical and hematological parameters of dairy Baladi goats.

    abstract：:The objective of this study was to elucidate the impact of lactation stage on milk composition, hematological and biochemical parameters of dairy Baladi goats under Egyptian conditions. Forty-eight Baladi goats (32.8 ± 2.9 kg of BW) were enrolled in the current study. The lactation period has been divided into three s...

    journal_title：Saudi journal of biological sciences

    pub_type： 杂志文章

    doi：10.1016/j.sjbs.2016.08.003

    authors： El-Tarabany MS,El-Tarabany AA,Roushdy EM

    更新日期：2018-12-01 00:00:00