Ledipasvir/sofosbuvir fixed-dose combination tablet in Taiwanese patients with chronic genotype 1 hepatitis C virus.

abstract：BACKGROUND AND AIM:This study investigated whether diabetes mellitus (DM) increased the risk of pancreatic cancer and whether anti-diabetic drugs reduced the risk in Taiwan. METHODS:We designed a population-based cohort study using the Taiwan National Health Insurance Database, which consisted of 49,803 patients aged ...

journal_title：Journal of gastroenterology and hepatology

authors： Liao KF,Lai SW,Li CI,Chen WC

更新日期：2012-04-01 00:00:00

abstract：:Inflammatory bowel disease (IBD) was previously thought to be rare in Asia, but emerging data indicate rising incidence and prevalence of IBD in the region. The Asia Pacific Working Group on Inflammatory Bowel Disease was established in Cebu, Philippines, at the Asia Pacific Digestive Week conference in 2006 under the...

journal_title：Journal of gastroenterology and hepatology

authors： Ooi CJ,Makharia GK,Hilmi I,Gibson PR,Fock KM,Ahuja V,Ling KL,Lim WC,Thia KT,Wei SC,Leung WK,Koh PK,Gearry RB,Goh KL,Ouyang Q,Sollano J,Manatsathit S,de Silva HJ,Rerknimitr R,Pisespongsa P,Abu Hassan MR,Sung J,

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND AND AIM:The purpose of this study was to describe the computed tomography (CT) findings of sorafenib-treated hepatic tumors in patients with advanced hepatocellular carcinoma and to correlate the findings to the overall survival (OS). METHODS:Twenty-eight sorafenib-treated patients who had advanced hepatoce...

journal_title：Journal of gastroenterology and hepatology

authors： Kim MJ,Choi JI,Lee JS,Park JW

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND AND AIM:The oral manifestations of familial adenomatous polyposis (FAP) have been reported in the recent literature. Therefore, there has been growing interest in the characterization of the dento-osseous anomalies because they may precede colorectal cancer and may be used as a diagnostic marker. This system...

journal_title：Journal of gastroenterology and hepatology

authors： Almeida FT,Pachêco-Pereira C,Porporatti AL,Flores-Mir C,Leite AF,De Luca Canto G,Guerra EN

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Prostaglandin analogs have the pharmacologic effect of speeding up small intestinal transit (SIT). It remains unknown whether some gut peptides also mediate this enhancement. We studied the effect of misoprostol on rat SIT and looked at the role of vasoactive intestinal polypeptide (VIP) release dur...

journal_title：Journal of gastroenterology and hepatology

authors： Chang FY,Doong ML,Chen TS,Lee SD,Wang PS

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND AND AIM:Nonalcoholic fatty liver disease (NAFLD) is becoming an increasingly important health issue. However, there are no data on the change in prevalence of NAFLD within a population over time, especially in the mainland of China. The goal of this study was to estimate the pooled prevalence of NAFLD in the...

journal_title：Journal of gastroenterology and hepatology

authors： Li Z,Xue J,Chen P,Chen L,Yan S,Liu L

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND AND AIM:Simultaneous and metachronous head and neck cancers are likely to develop in patients with current or previous esophageal cancer. The Valsalva maneuver facilitates the visualization of the hypopharyngeal area during endoscopic observation, but it requires transnasal endoscopy. We developed a novel Va...

journal_title：Journal of gastroenterology and hepatology

authors： Iwatsubo T,Ishihara R,Nakagawa K,Ohmori M,Iwagami H,Matsuno K,Inoue S,Nakahira H,Matsuura N,Shichijo S,Maekawa A,Kanesaka T,Yamamoto S,Takeuchi Y,Higashino K,Uedo N,Higuchi K

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND AND AIM:To investigate the relationship between human leptin receptor (LEPR) gene G3057A polymorphism and type 2 diabetes mellitus (T2DM) patients complicated with or without non-alcoholic fatty liver disease (NAFLD). METHODS:Two hundred and sixteen cases of newly diagnosed T2DM patients (104 cases complica...

journal_title：Journal of gastroenterology and hepatology

authors： Lu H,Sun J,Sun L,Shu X,Xu Y,Xie D

更新日期：2009-02-01 00:00:00

abstract：:Much has been achieved in Helicobacter pylori research, to the point that the growth of new knowledge is bound to slow down. However, expectations for further developments remain high. Knowledge about the characteristic organism and behaviour is already extensive. Particularly intriguing are the differences in genetic...

journal_title：Journal of gastroenterology and hepatology

authors： Tytgat G

更新日期：2000-10-01 00:00:00

abstract：:The Steering Committee for the Prevention and Control of Infectious Diseases in Asia recently conducted a survey of primary-care physicians in Asia, which revealed that many physicians administer boosters in their clinical practice and that there is considerable variation and uncertainty among physicians regarding thi...

journal_title：Journal of gastroenterology and hepatology

authors： John TJ,Cooksley G,Steering Committee for the Prevention and Control of Infectious Diseases in Asia.

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Both clinical outcomes and factors predictive for poor response after an initial course of corticosteroids have not yet been well established in the treatment of moderate to severe ulcerative colitis (UC). We therefore evaluated the short- and long-term effects of corticosteroids and prognostic fact...

journal_title：Journal of gastroenterology and hepatology

authors： Yoon JY,Cheon JH,Park JJ,Hong SP,Kim TI,Kim WH

更新日期：2011-07-01 00:00:00

abstract：:The author visited China in 1981 and 1984 and obtained data comparing the incidence of duodenal ulcer in the rice eating districts of the south with the incidence in the wheat, maize and millet eating areas of the north. The evidence suggested a higher prevalence of duodenal ulcer in the rice eating areas than in the ...

journal_title：Journal of gastroenterology and hepatology

authors： Tovey FI

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND AND AIM:Endoscopic transmural drainage has been recognized as the first-line treatment for pancreatic fluid collection (PFC). Currently, three different types of stents have been extensively applied, including double pigtail plastic stent (PS), fully covered self-expanding metal stent (FCSEMS), and novel lum...

journal_title：Journal of gastroenterology and hepatology

authors： Wang Z,Zhao S,Meng Q,Wang S,Chen Y,Wang F,Li Q,Yao J,Du Y,Jin Z,Bai Y,Li Z,Wang D

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND AND AIMS:The high recurrence of hepatolithiasis and high operative trauma of hepatectomy necessitate new therapeutic approaches. Thus, this study was designed to (i) investigate the effectiveness of chemical biliary duct embolization (CBDE) for chemical hepatectomy; and (ii) to determine the mechanism of CBD...

journal_title：Journal of gastroenterology and hepatology

authors： Li FY,Cheng JQ,Li N,He S,Zhang MM,Dong JH,Jiang LS,Cheng NS

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND AND AIM:We recently conducted a randomized placebo-controlled trial on the efficacy and safety of rikkunshito, a standardized Japanese herbal medicine, for the treatment of functional dyspepsia (FD). The present post-hoc study aimed to evaluate the differences in clinical characteristics between responders a...

journal_title：Journal of gastroenterology and hepatology

authors： Togawa K,Matsuzaki J,Kobayakawa M,Fukushima Y,Suzaki F,Kasugai K,Nishizawa T,Naito Y,Hayakawa T,Kamiya T,Andoh T,Yoshida H,Tokura Y,Nagata H,Mori M,Kato K,Hosoda H,Takebayashi T,Miura S,Uemura N,Joh T,Hibi T,S

更新日期：2016-02-01 00:00:00

abstract：:The loss of haemolytic activity in sera during storage at low temperature (the cold activation of complement) was observed in 136 of 184 (74%) patients with chronic liver disease associated with hepatitis C virus (HCV) infection. This was more frequent than observed in the three of 40 (8%) patients with chronic hepati...

journal_title：Journal of gastroenterology and hepatology

authors： Aikawa T,Kimura I,Kojima M,Ueno C,Miyamoto K,Tango T,Tanaka N

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND AND AIM:The authors' previous report revealed that endothelin-1 might be released from B lymphocytes in cirrhotic patients with hypersplenism. Other investigators have shown that persistent exposure to environmental contaminants including arsenic might induce idiopathic portal hypertension. The aim of this s...

journal_title：Journal of gastroenterology and hepatology

authors： Yamaguchi E,Yamanoi A,Ono T,Nagasue N

更新日期：2007-07-01 00:00:00

abstract：:The mechanism of phagocytosis by Kupffer cells has been shown to be related to the Ca(2+)-calmodulin and the actomyosin systems. However the role of the transmembrane signal transmitter, G-protein, is still unknown. In this study, a quantitative evaluation of phagocytosis by Kupffer cells of rats in culture and the ef...

journal_title：Journal of gastroenterology and hepatology

authors： Hirose M,Watanabe S,Ueno T,Kitami N,Sato N

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND AND AIM:Current treatments of functional dyspepsia (FD) are unsatisfied. Tricyclic antidepressants alter visceral hypersensitivity and brain-gut interaction. We assessed the efficacy and safety of nortriptyline in patients with FD. METHODS:Patients diagnosed with FD according to Rome III criteria who failed...

journal_title：Journal of gastroenterology and hepatology

authors： Kaosombatwattana U,Pongprasobchai S,Limsrivilai J,Maneerattanaporn M,Leelakusolvong S,Tanwandee T

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:The objective of three-dimensional (3-D) endoscopic ultrasonography (EUS) is to recognize lesions stereoscopically. METHODS AND RESULTS:We investigated a total of 43 lesions in the upper gastrointestinal (GI) tract by regenerating 3-D images in eight cases of oesophageal cancer, two cases of oesophageal sub...

journal_title：Journal of gastroenterology and hepatology

authors： Tokiyama H,Yanai H,Nakamura H,Takeo Y,Yoshida T,Okita K

更新日期：1999-12-01 00:00:00

abstract：AIMS:To investigate the relations between the formation of pigment gallstone and the function of the intestinal mucosal barrier, as well as the underlying mechanism. METHODS:Eighty guinea pigs were randomly divided into three groups in which they were respectively given normal diet, gallstone-causing diet, and gallsto...

journal_title：Journal of gastroenterology and hepatology

authors： Su Y,Wu S,Fan Y,Jin J,Zhang Z

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND AND AIM:We aimed to validate the non-invasive criteria for the characterization of portal vein thrombosis (PVT) in patients with cirrhosis and hepatocellular carcinoma (HCC). In a prospective study, we examined the impact of arterial hypervascularity, as established by the European Association for the Study ...

journal_title：Journal of gastroenterology and hepatology

authors： Sorrentino P,Tarantino L,D'Angelo S,Terracciano L,Ferbo U,Bracigliano A,Panico L,De Chiara G,Lepore M,De Stefano N,Fiorentino F,Vecchione R

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND AND AIM:The prevalence of ulcerative colitis (UC) is increasing steadily in Japan. In Western countries, a bimodal distribution, with UC onset peaks in youth and middle age, is observed, and smoking cessation is reported as a risk factor for UC. However, there are few reports on a bimodal distribution of ons...

journal_title：Journal of gastroenterology and hepatology

authors： Takahashi H,Matsui T,Hisabe T,Hirai F,Takatsu N,Tsurumi K,Kanemitsu T,Sato Y,Kinjyo K,Yano Y,Takaki Y,Nagahama T,Yao K,Washio M

更新日期：2014-08-01 00:00:00

abstract：:Maintaining high levels of intracellular cyclic AMP (cAMP) is known to inhibit the growth of various proliferating cells including hepatocytes. We show here that transient (30 min) elevations of cAMP induced by addition of 8-bromo-cAMP (1 mmol/L) to rat hepatocytes in primary culture at three time points (12 h, 16 h a...

journal_title：Journal of gastroenterology and hepatology

authors： Kikukawa M,Okamoto Y,Nakano H

更新日期：1998-06-01 00:00:00

abstract：:Infiltrating leucocytes are activated to generate reactive oxygen species or to produce several molecules in inflamed colonic mucosa. To clarify the phenotypical and functional properties of activating cells in colitic mucosa, 23 patients with ulcerative colitis and 13 controls were studied using a combined method for...

journal_title：Journal of gastroenterology and hepatology

authors： Oshitani N,Sawa Y,Hara J,Adachi K,Nakamura S,Matsumoto T,Arakawa T,Kuroki T

更新日期：1997-12-01 00:00:00

abstract：BACKGROUND:We designed an animal model in order to clarify whether Helicobacter pylori infection causes the gastric mucosal lesion frequently seen in cirrhotic patients. METHODS:Ammonia (NH3) solution was given to rats with carbon tetrachloride-induced cirrhosis. The gastric mucosal hexosamine (Hx) content and histopa...

journal_title：Journal of gastroenterology and hepatology

authors： Sugimoto M,Machida Y,Ito K

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND AND AIM:The activation of Rho proteins has been shown to lead to loss of polarity in cancer cells, as well as reorganization of the cytoskeleton and facilitation of cell motility, possibly resulting in their malignant potential. The clinicopathological significance of RhoA, however, is not yet well known in ...

journal_title：Journal of gastroenterology and hepatology

authors： Wang D,Dou K,Xiang H,Song Z,Zhao Q,Chen Y,Li Y

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND AND AIM:The effect of solid debris on walled-off necrosis (WON) drainage remains unknown. Our study evaluated the role of solid debris in endoscopic ultrasound (EUS)-guided drainage of WON compared lumen-apposing metal stent (LAMS) with double-pigtail plastic stent (DPPS). METHODS:We retrospectively evaluat...

journal_title：Journal of gastroenterology and hepatology

authors： Zhu H,Xie P,Wang Y,Jin Z,Li Z,Du Y

更新日期：2020-05-04 00:00:00

abstract：:The in vitro binding of 125I-labelled human alpha-interferon to peripheral blood mononuclear cells from 13 patients with chronic hepatitis B during interferon therapy was assayed in order to identify changes in the number of interferon receptors during treatment. Nine patients were treated with human alpha-interferon ...

journal_title：Journal of gastroenterology and hepatology

authors： Nakajima S,Kuroki T,Kurai O,Kobayashi K,Yamamoto S

更新日期：1989-09-01 00:00:00

abstract：BACKGROUND AND AIM:Exportin 4 (XPO4) is a recently-discovered candidate tumor-suppressor gene identified in a liver cancer mouse model. To investigate the role of XPO4 in hepatocellular carcinoma (HCC) pathogenesis, we determined XPO4 expression and its correlation to prognosis in human primary HCC. METHODS:The XPO4 m...

journal_title：Journal of gastroenterology and hepatology

authors： Liang XT,Pan K,Chen MS,Li JJ,Wang H,Zhao JJ,Sun JC,Chen YB,Ma HQ,Wang QJ,Xia JC

更新日期：2011-03-01 00:00:00