Decreased expression of XPO4 is associated with poor prognosis in hepatocellular carcinoma.

abstract：BACKGROUND AND AIM:The incidence of colorectal cancer (CC) is increasing in many Asian countries, but decreasing in western countries. The present study examined the local incidence of CC in the past few decades. METHODS:A population based study, using data from Hong Kong (HK) Cancer Registry, was carried out to exami...

journal_title：Journal of gastroenterology and hepatology

authors： Yee YK,Gu Q,Hung I,Tan VP,Chan P,Hsu A,Pang R,Lam CS,Wong BC

更新日期：2010-05-01 00:00:00

abstract：:The in vitro binding of 125I-labelled human alpha-interferon to peripheral blood mononuclear cells from 13 patients with chronic hepatitis B during interferon therapy was assayed in order to identify changes in the number of interferon receptors during treatment. Nine patients were treated with human alpha-interferon ...

journal_title：Journal of gastroenterology and hepatology

authors： Nakajima S,Kuroki T,Kurai O,Kobayashi K,Yamamoto S

更新日期：1989-09-01 00:00:00

abstract：BACKGROUND AND AIM:Colorectal cancer (CRC) screening is based on colonoscopy or fecal occult blood tests, but is imperfect and costly. The Asia Pacific Colorectal Screening Score (APCS) is derived from age, sex, family history of CRC, and smoking history and has been validated in Asian populations. Validation in a West...

journal_title：Journal of gastroenterology and hepatology

authors： Corte C,Zhang L,Chen J,Westbury S,Shaw J,Yeoh KG,Leong R

更新日期：2016-02-01 00:00:00

abstract：:The exact pathogenesis of centrilobular necrosis following congestion of the liver is still unknown. We reviewed the clinical data related to systemic circulatory disturbance and histopathology of the liver and the gut in 320 autopsy subjects. Congestion of the liver alone was associated only with atrophy and loss of ...

journal_title：Journal of gastroenterology and hepatology

authors： Shibayama Y,Urano T,Asaka S,Hashimoto K,Nakata K

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:It has been reported that cathepsin E (CTSE) is a non-secretory and intracellular aspartic proteinase found in the superficial epithelial cells of the stomach and that it is also expressed in pancreatic ductal adenocarcinoma. We evaluated the diagnostic value of CTSE in the pancreatic juice in the diagnosis ...

journal_title：Journal of gastroenterology and hepatology

authors： Uno K,Azuma T,Nakajima M,Yasuda K,Hayakumo T,Mukai H,Sakai T,Kawai K

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND AND AIMS:The aim of this study was to clinicopathologically distinguish the pathogenesis of gastric mucosa-associated lymphoid tissue (MALT) lymphoma and diffuse large B-cell lymphoma without a MALT lymphoma component (DLL). METHODS:We investigated clinicopathological features of these gastric lymphomas inc...

journal_title：Journal of gastroenterology and hepatology

authors： Hiyama T,Haruma K,Kitadai Y,Masuda H,Miyamoto M,Ito M,Kamada T,Tanaka S,Uemura N,Yoshihara M,Sumii K,Shimamoto F,Chayama K

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND AND AIM:The fibrosis stage of non-alcoholic fatty liver disease (NAFLD) is closely associated with long-term prognosis, including liver-related mortality. However, it is not yet clear whether noninvasive fibrosis markers can predict the incidence of non-liver-related complications in Japanese NAFLD. In this ...

journal_title：Journal of gastroenterology and hepatology

authors： Ito T,Ishigami M,Ishizu Y,Kuzuya T,Honda T,Hayashi K,Nishimura D,Toyoda H,Kumada T,Goto H,Hirooka Y

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND AND AIM:Same-day bidirectional endoscopy (BDE) is a commonly performed procedure, but the optimal sequence for the procedure with moderate conscious sedation is not well established. This study investigated the optimal sequence for same-day BDE under moderate conscious sedation and carbon dioxide insufflatio...

journal_title：Journal of gastroenterology and hepatology

authors： Chen SW,Cheng CL,Liu NJ,Tang JH,Kuo YL,Lin CH,Tsui YN,Lee BP,Hung HL

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND AND AIM:Increased production of reactive oxygen species, which cause oxidative DNA damage, is considered to be related to hepatocarcinogenesis. 8-Hydroxy-2'-deoxy-guanosine (8-OHdG) is a useful marker of DNA damage induced by oxidative stress. The aim of this study was to determine whether expression of 8-OH...

journal_title：Journal of gastroenterology and hepatology

authors： Chuma M,Hige S,Nakanishi M,Ogawa K,Natsuizaka M,Yamamoto Y,Asaka M

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND AND AIM:Dendritic cells (DCs) are observed on the Helicobacter pylori-infected gastric mucosa. DCs generally play an important role in the regulation of inflammation. Although stimulation of gastric epithelial cells with H. pylori vacuolating cytotoxin (VacA) has been reported to induce apoptosis and endopla...

journal_title：Journal of gastroenterology and hepatology

authors： Kim JM,Kim JS,Kim N,Ko SH,Jeon JI,Kim YJ

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND AND AIM:Early life exposure to the famine may affect the susceptibility to the metabolic disorders. The objective of this study was to examine the associations of early life exposure to the Chinese Famine (1959-1961) with the risk of fatty liver disease, obesity, hypertension, and hyperglycemia in adulthood....

journal_title：Journal of gastroenterology and hepatology

authors： Chen JP,Peng B,Tang L,Sun R,Hu S,Wen XY,Que P,Wang YH

更新日期：2016-01-01 00:00:00

abstract：:Wilson's disease is an autosomal recessive, inborn error of copper metabolism. The basic defect is unknown but decreased biliary excretion of copper is associated with copper accumulation and damage to the liver, brain and other organs with variable clinical expression. The gene for the disease has been mapped to band...

journal_title：Journal of gastroenterology and hepatology

authors： Frydman M

更新日期：1990-07-01 00:00:00

abstract：BACKGROUND AND AIM:Entecavir (ETV) induces biochemical and histologic improvement of the liver in patients with chronic hepatitis B. This study aimed to confirm that 2 years of ETV treatment improves liver function and non-invasive fibrosis markers in patients with hepatitis B virus (HBV)-associated cirrhosis. METHODS...

journal_title：Journal of gastroenterology and hepatology

authors： Shin SK,Kim JH,Park H,Kwon OS,Lee HJ,Yeon JE,Byun KS,Suh SJ,Yim HJ,Kim YS,Kim JH

更新日期：2015-12-01 00:00:00

abstract：:Two intertwined compartments coexisting in nonpolypoid conventional (i.e. tubular or villous) adenomas are highlighted in this review: one built of dysplastic tissue on top and the other portraying crypts with irregular, corrupted shapes, albeit lined with normal epithelium, below. The latter compartment has remained ...

journal_title：Journal of gastroenterology and hepatology

authors： Rubio CA

更新日期：2020-08-05 00:00:00

abstract：BACKGROUND AND AIM:HFE mutations, a common cause of hereditary hemochromatosis (HH), are reportedly associated with hepatic iron overload, severe liver fibrosis, and good response to interferon treatment in European patients with chronic hepatitis C (CHC). HH shows ethnicity-based differences and little is known about ...

journal_title：Journal of gastroenterology and hepatology

authors： Ishizu Y,Katano Y,Honda T,Hayashi K,Ishigami M,Itoh A,Hirooka Y,Nakano I,Goto H

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:We previously developed a new diagnostic method for Helicobacter pylori infection and called it the endoscopic [13C]-urea breath test (EUBT). Here we evaluate the relationship between the EUBT results and the histological findings. METHODS:The EUBT was performed on 137 patients with gastroduodenal diseases....

journal_title：Journal of gastroenterology and hepatology

authors： Suto H,Azuma T,Ito S,Ito Y,Miyaji H,Yamazaki Y,Kohli Y,Kuriyama M

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND AND AIM:Repeated water avoidance stress (WAS) induces visceral hypersensitivity. Additionally, it is also known to activate corticotropin-releasing factor (CRF), mast cells, and pro-inflammatory cytokines systems, but their precise roles on visceral sensation have not been determined definitely. The aim of t...

journal_title：Journal of gastroenterology and hepatology

authors： Nozu T,Miyagishi S,Nozu R,Takakusaki K,Okumura T

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND AND AIM:The conventional method of anatomical right hemihepatectomy (ARHH) requires hilus dissection. We report a method without hilus dissection to minimize intraoperative bleeding. METHODS:We retrospectively evaluated data of 107 patients who received ARHH involving ligation of corresponding inflow and ou...

journal_title：Journal of gastroenterology and hepatology

authors： Chen XP,Zhang ZW,Huang ZY,Chen YF,Zhang WG,Qiu FZ

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Low-grade erosive esophagitis (i.e. Los Angeles grade A) is the most predominant type of esophagitis in Japan. It is unclear whether all the mucosal breaks detected by conventional endoscopy are indicative of esophageal mucosal erosion. Hospital-based, cross-sectional, cross-over, observational stud...

journal_title：Journal of gastroenterology and hepatology

authors： Amano Y,Yamashita H,Koshino K,Ohshima T,Miwa H,Iwakiri R,Fujimoto K,Manabe N,Haruma K,Kinoshita Y

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND AND AIM:Whether an early use of azathioprine (AZA) can alter the natural history of Crohn's disease (CD) remains debated. The aim of this study is to evaluate the impact of AZA on disease progression in a cohort of patients with early CD. METHODS:This longitudinal cohort study examined patients with early C...

journal_title：Journal of gastroenterology and hepatology

authors： Qiu Y,Chen BL,Feng R,Zhang SH,He Y,Zeng ZR,Ben-Horin S,Peyrin-Biroulet L,Mao R,Chen MH

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Patients with cirrhosis exhibit splanchnic, peripheral and pulmonary vasodilation, which are thought to play a role in increasing portal pressure, promoting sodium retention and determining arterial hypoxaemia. The present study investigated whether these abnormalities are influenced by portal hypertension o...

journal_title：Journal of gastroenterology and hepatology

authors： Luca A,García-Pagán JC,de Lacy AM,Escorsell A,Feu F,Visa J,Bosch J,Rodés J

更新日期：1999-11-01 00:00:00

abstract：:The identification of activated hepatic stellate cells and related cell types as key fibrogenic effectors during liver injury has led to intense evaluation of transcriptional events underlying their behavior. While initial studies focused on characterizing interactions between transcription factors and regulatory regi...

journal_title：Journal of gastroenterology and hepatology

authors： Friedman SL

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:Poly-adenosine diphosphate (ADP)-ribosylation, catalysed by poly(ADP-ribose) polymerase (PARP), is a post-translational modification of nuclear proteins and is involved in a wide range of biological processes including DNA repair, cell proliferation and malignant transformation. Alteration of this reaction i...

journal_title：Journal of gastroenterology and hepatology

authors： Nomura F,Yaguchi M,Togawa A,Miyazaki M,Isobe K,Miyake M,Noda M,Nakai T

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND AND AIMS:Hyposplenism has been described in patients with alcoholic cirrhosis (AC). However, no data are available regarding hyposplenism in patients with non-alcoholic cirrhosis (NAC) and other forms of portal hypertension such as extrahepatic portal venous obstruction (EHPVO). The aim is to study the splen...

journal_title：Journal of gastroenterology and hepatology

authors： Satapathy SK,Narayan S,Varma N,Dhiman RK,Varma S,Chawla Y

更新日期：2001-09-01 00:00:00

abstract：:One of the characteristic features of the majority of pancreatic ductal adenocarcinomas is an abundant desmoplastic/stromal reaction. Until recently, this stroma had received little attention from researchers studying the pathogenesis of pancreatic cancer, with most of the research focus resting on the biology of tumo...

journal_title：Journal of gastroenterology and hepatology

authors： Apte MV,Wilson JS

更新日期：2012-03-01 00:00:00

abstract：:Chronic pancreatitis (CP) is a disease characterized by irreversible destruction and fibrosis of the parenchyma, leading to pancreatic exocrine insufficiency. In developed countries, the etiology for 60% to 70% of CP amongst male patients is alcohol and 25% are classified as idiopathic chronic pancreatitis (ICP). The ...

journal_title：Journal of gastroenterology and hepatology

authors： Reddy DN,Prasad SS

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND AND AIM:Liver stiffness measurement (LSM) with transient elastography is a non-invasive and reliable test for liver fibrosis. However a small proportion of patients may have unreliable LSM or LSM failure. The aim of the present study was to investigate the factors associated with unreliable LSM or LSM failur...

journal_title：Journal of gastroenterology and hepatology

authors： Wong GL,Wong VW,Chim AM,Yiu KK,Chu SH,Li MK,Chan HL

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Experimental acute gastric ulcerations (EAGU) are healed very rapidly. This healing process has two steps; mucosal restitution and delayed repair. Adenosine 5'-triphosphate (ATP)-dependent potassium channels (K(ATP)) have a regulatory role in the gastrointestinal physiology. In the present study, th...

journal_title：Journal of gastroenterology and hepatology

authors： Rahgozar M,Pazokitoroudi H,Bakhtiarian A,Djahanguiri B

更新日期：2001-03-01 00:00:00

abstract：:Advances in technology have made possible the clinical application of magnetic resonance cholangiography, endoscopic, intra-operative and laparoscopic ultrasound in the study of the biliary tree, in addition to conventional magnetic resonance imaging and transabdominal ultrasound. The role of the conventional, as well...

journal_title：Journal of gastroenterology and hepatology

authors： Chan YL

更新日期：1998-11-01 00:00:00

abstract：:Despite a high prevalence of liver disease in Viet Nam, there has been no nationwide approach to the disease and no systematic screening of at-risk individuals. Risk factors include chronic hepatitis B (estimated prevalence of 12%), chronic hepatitis C (at least 2% prevalence), and heavy consumption of alcohol among m...

journal_title：Journal of gastroenterology and hepatology

authors： Gish RG,Bui TD,Nguyen CT,Nguyen DT,Tran HV,Tran DM,Trinh HN,International Group for Liver Health in Viet Nam.

更新日期：2012-02-01 00:00:00