Cancer of the ovary, fallopian tube, and peritoneum: a population-based comparison of the prognostic factors and outcomes.

abstract：:Syrian golden hamsters received weekly s.c. doses of 5.0, 2.5, 1.25 or 0.63 mg/kg b.w. vinylethylnitrosamine (VEN). As dose levels increased, average survival time decreased, tumor multiplicity increased as did the total tumor rate which was between 50% and 100%. The main target of VEN effect was the respiratory tract...

journal_title：Journal of cancer research and clinical oncology

authors： Green U,Althoff J

更新日期：1982-01-01 00:00:00

abstract：PURPOSE:Recently, it was reported that expression of transglutaminase 2 plays an important role in doxorubicin/cisplatin resistance in breast and ovarian cancer. The aims of this study were to verify the role of transglutaminase 2 in cisplatin response in non-small cell lung cancer (NSCLC) and to study if transglutamin...

journal_title：Journal of cancer research and clinical oncology

authors： Park KS,Kim HK,Lee JH,Choi YB,Park SY,Yang SH,Kim SY,Hong KM

更新日期：2010-04-01 00:00:00

abstract：:A previous cohort-study in a cardboard factory demonstrated that high and prolonged occupational exposure to trichloroethene (C2HCl3) is associated with an increased incidence of renal cell cancer. The present hospital-based case/control study investigates occupational exposure in 58 patients with renal cell cancer wi...

journal_title：Journal of cancer research and clinical oncology

authors： Vamvakas S,Brüning T,Thomasson B,Lammert M,Baumüller A,Bolt HM,Dekant W,Birner G,Henschler D,Ulm K

更新日期：1998-01-01 00:00:00

abstract：PURPOSE:Our goal was to prospectively evaluate self-reported quality-of-life (QoL) during second-line therapy in 51 consecutive patients with cytokine-refractory kidney cancer treated with sorafenib or sunitinib. METHODS:QoL was assessed by the EORTC QoL questionnaire QLQ-C30 at baseline and at weeks 4, 6, 10, 12 and ...

journal_title：Journal of cancer research and clinical oncology

authors： Herrmann E,Gerss J,Bierer S,Köpke T,Bolenz C,Hertle L,Wülfing C

更新日期：2009-01-01 00:00:00

abstract：:In the human gastric adenocarcinoma cell line AGS the effects of the protein-kinase-C-activating phorbol ester 12-O-tetradecanoylphorbol 13-acetate (TPA), the protein kinase C inhibitor staurosporine, the adenylate-cyclase activating agent forskolin, and the permeable dibutyryl-adenosine 3',5'-monophosphate (Bt2cAMP) ...

journal_title：Journal of cancer research and clinical oncology

authors： Piontek M,Hengels KJ,Porschen R,Strohmeyer G

更新日期：1993-01-01 00:00:00

abstract：:In the original publication, the 6th author's first name and the last name was inverted and incorrectly published. The correct author name is Letizia Ferella. ...

journal_title：Journal of cancer research and clinical oncology

authors： Marampon F,Leoni F,Mancini A,Pietrantoni I,Codenotti S,Ferella L,Megiorni F,Porro G,Galbiati E,Pozzi P,Mascagni P,Budillon A,Maggio R,Tombolini V,Fanzani A,Gravina GL,Festuccia C

更新日期：2019-09-01 00:00:00

abstract：:The relation between the intracellular glutathione (GSH) concentration and hydrogen-peroxide(H2O2)-induced cytotoxicity was investigated. The intracellular GSH concentration in human glioblastoma (T98G, U87MG) and glioma (KG1C) cell lines was one or two orders of magnitude higher than that in a human myelogenous leuke...

journal_title：Journal of cancer research and clinical oncology

authors： Iida M,Sunaga S,Hirota N,Kuribayashi N,Sakagami H,Takeda M,Matsumoto K

更新日期：1997-01-01 00:00:00

abstract：PURPOSE:Metastasizing epithelioid sarcoma (ES) is an extremely aggressive tumor, because conventional chemotherapy and irradiation are largely ineffective. Here, we analyzed the impact of the CD95-mediated drug-induced apoptosis in ES cell lines. METHODS:The effects of paclitaxel (Taxol) and 5-FU were determined by MT...

journal_title：Journal of cancer research and clinical oncology

authors： Heikaus S,Matuszek KS,Suschek CV,Ramp U,Reinecke P,Grinstein E,Haremza J,Gabbert HE,Mahotka C

更新日期：2008-06-01 00:00:00

abstract：:The proliferative activity in 70 cases of soft-tissue tumours was estimated immunohistochemically using the monoclonal antibody PC-10, which recognizes proliferating-cell nuclear antigen (PCNA) in paraffin sections. The PCNA index (i.e. the percentage of positive neoplastic nuclei) and to a lesser degree the PCNA coun...

journal_title：Journal of cancer research and clinical oncology

authors： Korkolopoulou P,Christodoulou P,Papanikolaou A,Tsenga A,Thomas-Tsagli E

更新日期：1994-01-01 00:00:00

abstract：:The long-term prognosis of surgery for hepatocellular carcinoma (HCC) is not yet satisfactory, the main reason being the high recurrence rate. The authors report the results of a long-term follow-up of 308 patients with HCC who became alpha-fetoprotein-(AFP)-negative after resection between 1975 and 1991. By March 199...

journal_title：Journal of cancer research and clinical oncology

authors： Zhou XD,Tang ZY,Yu YQ,Yang BH,Lu JZ,Lin ZY,Ma ZC,Zhang BH

更新日期：1994-01-01 00:00:00

abstract：:Lambda-DNA and plasmid pBR 322-DNA, respectively, were treated in vitro with increasing amounts of 4-S-ethanolsulfido-cyclophosphamide (CPA-P1). Subsequent digestion with restriction endonuclease Pvu II or Mbo II revealed discrete alterations in the cleavage patterns as compared to the controls, indicating subtle chan...

journal_title：Journal of cancer research and clinical oncology

authors： Lindemann H

更新日期：1985-01-01 00:00:00

abstract：:Mice with s.c. grafts of gastric carcinoma MKN45 or osteosarcoma 788T were injected i.v. with recombinant tumour necrosis factor alpha (rTNF alpha) and tumour blood flow rates were determined 4 h later as a fraction of the cardiac output g tissue-1. With MKN45, the tumour blood flow rate was significantly reduced from...

journal_title：Journal of cancer research and clinical oncology

authors： Pimm MV,Gribben SJ,Morris TM

更新日期：1991-01-01 00:00:00

abstract：:Human ovarian cancer cells from ten patients were cultured in the agar double layer assay as described by Hamburger and Salmon and in a methylcellulose monolayer system. The assays were compared under the same experimental conditions. The rate of positives (defined as greater than 30 colonies/dish) was 75% in the meth...

journal_title：Journal of cancer research and clinical oncology

authors： Runge HM,Neumann HA,Bücke W,Pfleiderer A

更新日期：1985-01-01 00:00:00

abstract：:The inducibility of cytotoxic T lymphocytes (CTL) that react with carcinoembryonic antigen (CEA) was tested in cancer patients with elevated (more than 5 ng/ml) serum CEA levels when antigen presentation was carried out with paraformaldehyde-fixed adhesive peripheral blood mononuclear cells (PBMC) from the patient tha...

journal_title：Journal of cancer research and clinical oncology

authors： Kim CH,Todoroki T,Matsumura M,Ohno T

更新日期：2000-07-01 00:00:00

abstract：PURPOSE:Metastatic renal cell carcinoma (mRCC) sometimes presents with an indolent course without any significant symptoms. Here, the potential impact of active surveillance (AS) on clinical outcomes in asymptomatic or minimally symptomatic mRCC patients was retrospectively evaluated. METHODS:mRCC patients who were fo...

journal_title：Journal of cancer research and clinical oncology

authors： Park I,Lee JL,Ahn JH,Lee DH,Lee KH,Jeong IG,Song C,Hong B,Hong JH,Ahn H

更新日期：2014-08-01 00:00:00

abstract：PURPOSE:Angiosarcoma of the scalp and face is a rare malignant endothelial tumor arising mainly in elderly people. The prognosis is poor. Effective and safe treatments are warranted. METHODS:A 79-year-old woman with an angiosarcoma of the scalp larger than 5 cm in diameter was treated with intravenous liposomal doxoru...

journal_title：Journal of cancer research and clinical oncology

authors： Wollina U,Füller J,Graefe T,Kaatz M,Lopatta E

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVES:Solitary plasmacytoma (SP) is characterized by a single mass of clonal plasma cells. Definitive RT can result in long-term local control of the SP. Due to the small number of patients and narrow range of doses, phase III randomized trials are lacking. The aim of this study is to further support the potential...

journal_title：Journal of cancer research and clinical oncology

authors： Alghisi A,Borghetti P,Maddalo M,Roccaro AM,Tucci A,Mazzola R,Magrini SM,Lo Casto A,Bonù ML,Tomasini D,Pasinetti N,Peretto G,Bertagna F,Tomasi C,Buglione M,Triggiani L

更新日期：2020-11-17 00:00:00

abstract：:The influence of infusion time and dose on the anticancer efficacy of 5-fluoro-2'-deoxyuridine (FdUrd) was investigated using a locoregional therapy model: Novikoff hepatoma transplanted i.m. into the thigh of Wistar rats and FdUrd infusion via a catheter implanted in the femoral artery. In experiment A the FdUrd dose...

journal_title：Journal of cancer research and clinical oncology

authors： Naser-Hijazi B,Berger MR,Schmähl D,Schlag P,Hull WE

更新日期：1991-01-01 00:00:00

abstract：PURPOSE:Oral cancer (OC) patients are at high risk to develop recurrent disease or secondary primary cancers with no available biomarkers to detect these events until a visible lesion is readily present and diagnosed by biopsy. Exosomes secreted by cancer cells are involved in tumor growth, invasion and metastasis. We ...

journal_title：Journal of cancer research and clinical oncology

authors： Zlotogorski-Hurvitz A,Dayan D,Chaushu G,Salo T,Vered M

更新日期：2016-01-01 00:00:00

abstract：:Soft-agar clonogenicity of L1210 mouse leukemia cells and of xenografts of a human melanoma and a carcinoma of the cervix was studied sectionally by the sizes of the colonies grown under hypoxic gradients and aerobic condition. Soft-agar plating efficiency was increased in cultured L1210 cells with decreasing oxygen c...

journal_title：Journal of cancer research and clinical oncology

authors： Fan D,Fan S,Morgan LR

更新日期：1984-01-01 00:00:00

abstract：:We measured an estrogen-receptor-associated protein (ER-D5), estrogen and progesterone receptors (ER; PgR) in samples obtained from 28 female patients with primary breast carcinoma. A correlation of r = 0.79 was found between ER-D5 and ER values and between ER-D5 and PgR values in premenopausal woman. In postmenopausa...

journal_title：Journal of cancer research and clinical oncology

authors： Navarro MA,Guardia M,Arranz B,Bonnin MR,Rosel P

更新日期：1989-01-01 00:00:00

abstract：PURPOSE:Transforming growth factor beta1 (TGF-beta1) and its receptor II (TGF-betaRII) are two key components of TGF-beta signaling and play an important role in carcinogenesis. Several functional polymorphisms were identified in TGFB1 and TGFBR2 and associated with elevated serum or plasma level of TGF-beta1 and enhan...

journal_title：Journal of cancer research and clinical oncology

authors： Jin G,Deng Y,Miao R,Hu Z,Zhou Y,Tan Y,Wang J,Hua Z,Ding W,Wang L,Chen W,Shen J,Wang X,Xu Y,Shen H

更新日期：2008-03-01 00:00:00

abstract：:In addition to spontaneous uterine endometrial adenocarcinomas at a high incidence (35.1%), development of endometrial hyperplasia/adenoma was also frequently detected in rats of the Donryu strain. The total yield of all observed proliferative endometrial lesions was very high (60.6%). The tumors arose commonly in the...

journal_title：Journal of cancer research and clinical oncology

authors： Nagaoka T,Onodera H,Matsushima Y,Todate A,Shibutani M,Ogasawara H,Maekawa A

更新日期：1990-01-01 00:00:00

abstract：:Human breast carcinomas were evaluated for estrogen and progesterone receptors by immunohistochemistry using monoclonal anti-receptor antibodies (n = 267) and by cytosol steroid-binding assays (n = 212). The estrogen and progesterone receptor contents of the tumors correlated with histological features of differentiat...

journal_title：Journal of cancer research and clinical oncology

authors： Helle M,Helin M,Isola J,Helin H

更新日期：1989-01-01 00:00:00

abstract：:Sarcoma 180 tumor tissue from C57 mice was processed in a soft agar clonogenic assay immediately after removal from the animal and after various methods of storage. The sensitivity to the antineoplastic drug cis-platinum was not affected by different storage methods. The highest yield of colony forming cells per 100 m...

journal_title：Journal of cancer research and clinical oncology

authors： Krischke W,Hartmann R,Schneider M,Schönenberger H

更新日期：1988-01-01 00:00:00

abstract：:Three human cell lines derived from Ewing's sarcoma (RM-82, VH-64, and WE-68) were investigated to establish the influence of recombinant human interferon gamma (rhIFN gamma) and tumour necrosis factor alpha (rhTNF alpha) on cell proliferation and survival and to characterize IFN gamma and TNF alpha receptor expressio...

journal_title：Journal of cancer research and clinical oncology

authors： van Valen F,Winkelmann W,Burdach S,Göbel U,Jürgens H

更新日期：1993-01-01 00:00:00

abstract：:The aim of our work was to investigate whether DNA topoisomerase II participates in the repair-specific incision of UV-irradiated genomic DNA. Therefore, the influence upon DNA incision of the topoisomerase II inhibitors (nalidixic and oxolinic acid, novobiocin and coumermycin A1) as well as the intercalating agent qu...

journal_title：Journal of cancer research and clinical oncology

authors： Thielmann HW,Popanda O,Edler L

更新日期：1991-01-01 00:00:00

abstract：PURPOSE:The aim of this study was to combine clinical pathologic variables that are associated with pathologic completer response (pCR) and relapse-free survival (RFS) after neoadjuvant chemotherapy into prediction nomograms. METHODS:A total of 370 stage II or III breast cancer patients who received neoadjuvant doceta...

journal_title：Journal of cancer research and clinical oncology

authors： Keam B,Im SA,Park S,Nam BH,Han SW,Oh DY,Kim JH,Lee SH,Han W,Kim DW,Kim TY,Park IA,Noh DY,Heo DS,Bang YJ

更新日期：2011-09-01 00:00:00

abstract：PURPOSE:Melanoma antigen gene A3 (MAGE-A3) is aberrantly expressed in a number of cancer types. Because of its high specificity, MAGE-A3 has shown to be a promising candidate for cancer immunotherapy. Dendritic cells (DCs) have emerged as the natural agents for antigen delivery. DCs transduced with antigen may increase...

journal_title：Journal of cancer research and clinical oncology

authors： Lin L,Wei J,Chen Y,Huang A,Li KK,Zhang W

更新日期：2014-02-01 00:00:00

abstract：PURPOSE:With the increasing interest in treatment decision-making based on risk prediction models, it is essential for clinicians to understand the steps in developing and interpreting such models. METHODS:A retrospective registry of 20 Dutch hospitals with data on patients treated for castration-resistant prostate ca...

journal_title：Journal of cancer research and clinical oncology

authors： Veen KM,de Angst IB,Mokhles MM,Westgeest HM,Kuppen M,Groot CAU,Gerritsen WR,Kil PJM,Takkenberg JJM

更新日期：2020-08-01 00:00:00