听力与言语-语言病理学

行为科学

医学伦理学

你正在浏览JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY期刊下所有文献
  • How to transfer traditional knowledge about medicinal herbs? or TCM plants: a black box for modern oncologists.

    abstract:OBJECTIVE:How could we transfer knowledge about healing plants from other cultures? We analyzed the results of literature search in two exemplary fields-oral mucositis and polyneuropathy. MATERIALS AND METHODS:In both systematic searches of existing literature, we found 57 studies investigating 68 plants from differen...

    journal_title:Journal of cancer research and clinical oncology

    pub_type: 杂志文章,评审

    doi:10.1007/s00432-020-03415-3

    authors: Büntzel J,Micke O,Büntzel J

    更新日期:2021-02-01 00:00:00

  • The botanical component p-hydroxycinnamic acid suppresses the growth and bone metastatic activity of human prostate cancer PC-3 cells in vitro.

    abstract::Bone metastatic prostate cancer is one of the most common malignancies in developed countries and the second leading cause of cancer-related death in men. There remains no effective treatment for metastatic prostate cancer. We investigate here the anticancer effects of botanical component p-hydroxycinnamic acid (HCA) ...

    journal_title:Journal of cancer research and clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s00432-020-03405-5

    authors: Yamaguchi M,Murata T,Ramos JW

    更新日期:2021-02-01 00:00:00

  • Re: Results of a randomized trial of treatment modalities in patients with low or early‑intermediate risk prostate cancer (PREFERE trial).

    abstract::The authors of this "Letter to the Editors" express their major concern about selective and biased reporting in this paper. ...

    journal_title:Journal of cancer research and clinical oncology

    pub_type: 信件

    doi:10.1007/s00432-020-03499-x

    authors: Boehle A,Kahmann F,Henkel TO,Zimmermann J,Machtens S

    更新日期:2021-01-28 00:00:00

  • Evaluation of the morphological features and unfavorable prognostic impact of dirty necrosis in renal cell carcinoma.

    abstract:PURPOSE:Tumor necrosis (TN) is one of the unfavorable prognostic factors in renal cell carcinoma (RCC). We identified two patterns of TN according to their morphology: dirty necrosis and ghost necrosis. We aimed to elucidate the morphological features and unfavorable prognostic impact of dirty necrosis in RCC. METHODS...

    journal_title:Journal of cancer research and clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s00432-020-03505-2

    authors: Kuroe T,Watanabe R,Kojima M,Morisue R,Sugano M,Kuwata T,Masuda H,Kusuhara S,Matsubara N,Oda S,Ushiku T,Ishii G

    更新日期:2021-01-21 00:00:00

  • Significance of boost dose for T4 nasopharyngeal carcinoma with residual primary lesion after intensity-modulated radiotherapy.

    abstract:BACKGROUND:Previous studies showed poorer survival in T4 disease with residual lesion. To evaluate the efficacy and toxicity of a boost dose for T4 nasopharyngeal carcinoma (NPC), patients with a residual primary lesion after intensity-modulated radiotherapy (IMRT). METHODS:398 T4 NPC patients with residual primary le...

    journal_title:Journal of cancer research and clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s00432-020-03479-1

    authors: Fei Z,Xu T,Qiu X,Li M,Chen T,Li L,Huang C,Chen C

    更新日期:2021-01-03 00:00:00

  • Overexpressed CA12 has prognostic value in pancreatic cancer and promotes tumor cell apoptosis via NF-κB signaling.

    abstract:INTRODUCTION:Pancreatic adenocarcinoma (PAAD) is among the deadliest forms of cancer globally. Carbonic anhydrase 12 (CA12) is known to play central roles in regulating many cancers, but its function in the context of PAAD is rarely discussed. This study was, therefore, designed to assess the expression of CA12 in PAAD...

    journal_title:Journal of cancer research and clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s00432-020-03447-9

    authors: Du Y,Xin Z,Liu T,Xu P,Mao F,Yao J

    更新日期:2021-01-02 00:00:00

  • Panel of potential lncRNA biomarkers can distinguish various types of liver malignant and benign tumors.

    abstract:PURPOSE:Liver cancers are among the deadliest malignancies due to a limited efficacy of early diagnostics, the lack of appropriate biomarkers and insufficient discrimination of different types of tumors by classic and molecular methods. In this study, we searched for novel long non-coding RNA (lncRNA) as well as valida...

    journal_title:Journal of cancer research and clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s00432-020-03378-5

    authors: Burenina OY,Lazarevich NL,Kustova IF,Shavochkina DA,Moroz EA,Kudashkin NE,Patyutko YI,Metelin AV,Kim EF,Skvortsov DA,Zatsepin TS,Rubtsova MP,Dontsova OA

    更新日期:2021-01-01 00:00:00

  • Age-stratified clinical performance and survival of patients with IDH-wildtype glioblastoma homogeneously treated by radiotherapy with concomitant and maintenance temozolomide.

    abstract:OBJECTIVE:Isocitrate dehydrogenase (IDH)-wildtype glioblastomas are the most malignant glial tumours. Median survival is only 14-16 months after diagnosis, with patients aged ≥ 65 years reportedly showing worse outcome. This study aimed to further evaluate the prognostic role of age in a homogenously treated patient co...

    journal_title:Journal of cancer research and clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s00432-020-03334-3

    authors: Berger K,Turowski B,Felsberg J,Malzkorn B,Reifenberger G,Steiger HJ,Budach W,Haussmann J,Knipps J,Rapp M,Hänggi D,Sabel M,Mijderwijk HJ,Kamp MA

    更新日期:2021-01-01 00:00:00

  • MET canonical transcript expression is a predictive biomarker for chemo-sensitivity to MET-inhibitors in hepatocellular carcinoma cell lines.

    abstract:PURPOSE:Long interspersed nuclear element 1 (LINE-1 or L1) is a dominant non-long terminal repeat (non-LTR) retrotransposon in the human genome that has been implicated in the overexpression of MET. Both the canonical MET and L1-MET transcripts are considered to play a role in hepatocellular carcinoma (HCC) development...

    journal_title:Journal of cancer research and clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s00432-020-03395-4

    authors: Rashed WM,Kandeil MA,Mahmoud MO,Maher D,Ezzat S,Abdel-Rahman MH

    更新日期:2021-01-01 00:00:00

  • Risk of lung cancer and renin-angiotensin blockade: a concise review.

    abstract:PURPOSE:The blockade of the renin-angiotensin-aldosterone system (RAAS) by angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin receptor blockers (ARBs) is one of the most common treatments for hypertension, heart failure and renal diseases. However, concerns have been raised about a possible link between RA...

    journal_title:Journal of cancer research and clinical oncology

    pub_type: 杂志文章,评审

    doi:10.1007/s00432-020-03445-x

    authors: Rachow T,Schiffl H,Lang SM

    更新日期:2021-01-01 00:00:00

  • Discrepancies between radiological and histological findings in preoperative core needle (CNB) and vacuum-assisted (VAB) breast biopsies.

    abstract:BACKGROUND:Ultrasound (US)-guided breast biopsy is a routine diagnostic method used to correlate imaging finding to a histological diagnosis which is still the gold standard in preoperative diagnostics. The accuracy of US-guided breast biopsies relies on a precise radiologic-histopathologic correlation, which is discus...

    journal_title:Journal of cancer research and clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s00432-020-03481-7

    authors: Jörg I,Wieler J,Elfgen C,Bolten K,Hutzli C,Talimi J,Vorburger D,Choschzick M,Moskovszky L,Dedes K,Varga Z

    更新日期:2020-12-07 00:00:00

  • Clinical characteristics and comparison of the outcome in young versus older patients with upper gastrointestinal carcinoma.

    abstract:BACKGROUND:The clinical behaviour and outcome of young patients with gastroesophageal tumours (GET) is surmised to differ from older patients, yet data on the comparison of these two patient subgroups is scarce. This study focuses on the investigation of the clinical characteristics and survival outcome of younger-age ...

    journal_title:Journal of cancer research and clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s00432-020-03302-x

    authors: Puhr HC,Karner A,Taghizadeh H,Jomrich G,Schoppmann SF,Preusser M,Ilhan-Mutlu A

    更新日期:2020-12-01 00:00:00

  • Surgical outcomes of second primary lung cancer after the extrapulmonary malignancy.

    abstract:OBJECTIVE:To study the surgical outcomes of patients with a second primary lung cancer after the extrapulmonary malignancy. MATERIALS AND METHODS:Patients who underwent surgical resection for lung cancers between January 2005 and December 2014 were reviewed. Clinical data, imaging characteristics of tumors, surgical a...

    journal_title:Journal of cancer research and clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s00432-020-03310-x

    authors: Ko KH,Huang HK,Chen YI,Chang H,Tsai WC,Huang TW

    更新日期:2020-12-01 00:00:00

  • PD-1 inhibition therapy for advanced cutaneous squamous cell carcinoma: a retrospective analysis from the University of Southern California.

    abstract:PURPOSE:Approximately 5% of patients with cutaneous squamous cell carcinoma (CSCC) may develop recurrent or metastatic disease. The management of such cases is challenging and requires multi-disciplinary care. Immunotherapy using PD-1 inhibition was approved to treat unresectable or metastatic CSCC in 2018. Given limit...

    journal_title:Journal of cancer research and clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s00432-020-03458-6

    authors: In GK,Vaidya P,Filkins A,Hermel DJ,King KG,Ragab O,Tseng WW,Swanson M,Kokot N,Lang JE,Menendez L,DeClerck B,Kim G,Hu JC,Terando A,Jadvar H,Ricker C,Miller KA,Peng DH,Wysong A

    更新日期:2020-11-18 00:00:00

  • Radiotherapy for the treatment of solitary plasmacytoma: 7-year outcomes by a mono-institutional experience.

    abstract:OBJECTIVES:Solitary plasmacytoma (SP) is characterized by a single mass of clonal plasma cells. Definitive RT can result in long-term local control of the SP. Due to the small number of patients and narrow range of doses, phase III randomized trials are lacking. The aim of this study is to further support the potential...

    journal_title:Journal of cancer research and clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s00432-020-03452-y

    authors: Alghisi A,Borghetti P,Maddalo M,Roccaro AM,Tucci A,Mazzola R,Magrini SM,Lo Casto A,Bonù ML,Tomasini D,Pasinetti N,Peretto G,Bertagna F,Tomasi C,Buglione M,Triggiani L

    更新日期:2020-11-17 00:00:00

  • Nab-paclitaxel plus S-1 versus nab-paclitaxel plus gemcitabine as first-line chemotherapy in patients with advanced pancreatic ductal adenocarcinoma: a randomized study.

    abstract:PURPOSE:To investigate the efficacy and safety of nab-paclitaxel plus S-1 (nab-P/S) versus nab-paclitaxel plus gemcitabine (nab-P/G) as first-line chemotherapy in patients with advanced pancreatic ductal adenocarcinoma (PDAC). METHODS:Treatment-naïve patients with advanced PDAC were equally randomized to receive nab-P...

    journal_title:Journal of cancer research and clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s00432-020-03442-0

    authors: Zong Y,Yuan J,Peng Z,Lu M,Wang X,Shen L,Zhou J

    更新日期:2020-11-15 00:00:00

  • Feasibility of limited resection for peripheral small-sized non-small cell lung cancer: a retrospective single-center-based study.

    abstract:PURPOSE:This study aimed to establish new criteria for limited resection of non-small cell lung cancer (NSCLC) based on computed tomography findings and maximum standardized uptake value (SUVmax). METHODS:Between December 2007 and December 2015, 611 patients underwent lung cancer surgery; of these, 70 with cT1aN0M0 wh...

    journal_title:Journal of cancer research and clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s00432-020-03441-1

    authors: Aragaki M,Hida Y,Kato T,Fujiwara-Kuroda A,Kaga K,Wakasa S

    更新日期:2020-11-05 00:00:00

  • Interferon alpha for essential thrombocythemia during 34 high-risk pregnancies: outcome and safety.

    abstract:PURPOSE:Pregnancies in women with essential thrombocythemia (ET) are at a higher risk for obstetrical complications. Acetylsalicylic acid (ASA) and low-molecular weight heparin (LMWH) are common options to prevent miscarriages and maternal complications, whereas interferon alpha (IFN) seems to be the cytoreductive ther...

    journal_title:Journal of cancer research and clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s00432-020-03430-4

    authors: Schrickel L,Heidel FH,Sadjadian P,Becker T,Kolatzki V,Hochhaus A,Griesshammer M,Wille K,German Study Group MPN, GSG-MPN.

    更新日期:2020-11-02 00:00:00

  • Gastric cancer in young patients: a separate entity with aggressive features and poor prognosis.

    abstract:PURPOSE:To investigate the clinicopathological features and survival outcomes between young and old patients with gastric cancer (GC), and further determine the role of young age in the prognosis of GC. METHODS:Patients with stage I-III gastric adenocarcinomas undergoing curative surgery were enrolled, divided into yo...

    journal_title:Journal of cancer research and clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s00432-020-03268-w

    authors: Cheng L,Chen S,Wu W,Kuo ZC,Wei Z,Meng S,Chen C,Zhang C,He Y

    更新日期:2020-11-01 00:00:00

  • The previously common post-kidney transplant Kaposi sarcoma has become non-existent for a decade: an Egyptian experience.

    abstract:BACKGROUND:De novo malignancy is a worrying complication after kidney transplantation; the type of which may vary due to factors such as the prevalence of viral infection and race. Kaposi sarcoma used to be the most common malignancy among our patients constituting more than one-third of cancers. Nevertheless, we notic...

    journal_title:Journal of cancer research and clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s00432-020-03433-1

    authors: Donia AF,Fouda MA,Ghoneim ME,Refaie AF,Ali-El-Dein B

    更新日期:2020-11-01 00:00:00

  • Using etoposide + dexamethasone-based regimens to treat nasal type extranodal natural killer/T-cell lymphoma-associated hemophagocytic lymphohistiocytosis.

    abstract:PURPOSE:Nasal type extranodal natural killer/T-cell lymphoma (ENKTL) can be associated with hemophagocytic lymphohistiocytosis (NK/T-LAHLH), which is a rare and fatal disease with no effective therapy. We evaluated whether etoposide + dexamethasone-based chemotherapy regimens might be useful for treating NK/T-LAHLH. M...

    journal_title:Journal of cancer research and clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s00432-020-03376-7

    authors: Wei L,Yang L,Cong J,Ye J,Li X,Yao N,Yang J,Ding J,Wang J

    更新日期:2020-10-06 00:00:00

  • A clinician's guide for developing a prediction model: a case study using real-world data of patients with castration-resistant prostate cancer.

    abstract:PURPOSE:With the increasing interest in treatment decision-making based on risk prediction models, it is essential for clinicians to understand the steps in developing and interpreting such models. METHODS:A retrospective registry of 20 Dutch hospitals with data on patients treated for castration-resistant prostate ca...

    journal_title:Journal of cancer research and clinical oncology

    pub_type: 杂志文章,评审

    doi:10.1007/s00432-020-03286-8

    authors: Veen KM,de Angst IB,Mokhles MM,Westgeest HM,Kuppen M,Groot CAU,Gerritsen WR,Kil PJM,Takkenberg JJM

    更新日期:2020-08-01 00:00:00

  • Risk stratification of postoperative recurrence in hypopharyngeal squamous-cell carcinoma patients with nodal metastasis.

    abstract:PURPOSE:To explore lymph node-related risk factors and investigate the benefit of different adjuvant therapy strategies in hypopharyngeal squamous-cell carcinoma (HPSCC) patients with nodal metastasis (N +). METHODS:We conducted a retrospective review covering 266 HPSCC patients with nodal metastasis. Kaplan-Meier cur...

    journal_title:Journal of cancer research and clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s00432-020-03337-0

    authors: Lin H,Wang T,Heng Y,Zhu X,Zhou L,Zhang M,Shi Y,Cao P,Tao L

    更新日期:2020-07-29 00:00:00

  • Molecular pathways in vulvar squamous cell carcinoma: implications for target therapeutic strategies.

    abstract:BACKGROUND:Additional prognostic factors and personalized therapeutic alternatives for vulvar squamous cell carcinoma (VSCC), especially for advanced stages with poor prognosis, are urgently needed. OBJECTIVES:To review and assess literature regarding underlying molecular mechanisms of VSCC target therapeutic and prog...

    journal_title:Journal of cancer research and clinical oncology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1007/s00432-020-03226-6

    authors: Giulia Mantovani,Fragomeni SM,Inzani F,Fagotti A,Della Corte L,Gentileschi S,Tagliaferri L,Zannoni GF,Scambia G,Garganese G

    更新日期:2020-07-01 00:00:00

  • Tricistronic expression of MOAP-1, Bax and RASSF1A in cancer cells enhances chemo-sensitization that requires BH3L domain of MOAP-1.

    abstract:PURPOSE:Although important for apoptosis, the signaling pathway involving MOAP-1(Modulator of Apoptosis 1), RASSF1A (RAS association domain family 1A), and Bax (Bcl-2 associated X protein) is likely to be dysfunctional in many types of human cancers due to mechanisms associated with gene mutation and DNA hyper-methylat...

    journal_title:Journal of cancer research and clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s00432-020-03231-9

    authors: Lee YH,Pang SW,Revai Lechtich E,Shah K,Simon SE,Ponnusamy S,Narayanan R,Poh CL,Tan KO

    更新日期:2020-07-01 00:00:00

  • A quick evaluation method of nosocomial infection risk for cancer hospitals during the COVID-19 pandemic.

    abstract::Nosocomial infections caused by COVID-19 will result in the immediate closure of the infected medical facility due to the highly contagious nature of COVID-19, further worsening medical shortages. We performed a Delphi consulting study to develop a risk model based on the experience of recently resumed activities in m...

    journal_title:Journal of cancer research and clinical oncology

    pub_type: 信件

    doi:10.1007/s00432-020-03235-5

    authors: Tang Z,Sun B,Xu B

    更新日期:2020-07-01 00:00:00

  • Proton therapy re-irradiation preserves health-related quality of life in large recurrent glioblastoma.

    abstract:PURPOSE:Proton therapy could minimize the risk of side effects and, therefore, reduce the possible detrimental effect on health-related quality of life (HRQOL) of re-irradiation. The aim of this study was to determine the effect of re-irradiation with active scanning proton therapy on recurrent glioblastoma (GBM) in te...

    journal_title:Journal of cancer research and clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s00432-020-03187-w

    authors: Scartoni D,Amelio D,Palumbo P,Giacomelli I,Amichetti M

    更新日期:2020-06-01 00:00:00

  • Ultrasound-mediated nanobubble destruction (UMND) facilitates the delivery of VEGFR2-targeted CD-TK-loaded cationic nanobubbles in the treatment of bladder cancer.

    abstract:BACKGROUND:The CD-TK double suicide gene has become an effective therapy for bladder cancer. A novel molecular-targeted ultrasound (US) method has been developed to precisely guide nanobubbles loaded with this gene to regions within bladder tumor cells and is widely used due to its efficiency in delivering drugs to the...

    journal_title:Journal of cancer research and clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s00432-020-03160-7

    authors: Hu C,Jiang D,Wu M,Wang J,Zhang R

    更新日期:2020-06-01 00:00:00

  • Clinical characteristics and outcomes of SDHB-related pheochromocytoma and paraganglioma in children and adolescents.

    abstract:PURPOSE:Pheochromocytomas/paragangliomas (PHEOs/PGLs) are rare in children with only a few SDHB mutation-related cases. Previous studies on children were conducted in small cohorts. This large set of pediatric patients provides robust data in the evaluation of clinical outcomes. METHODS:Sixty-four pediatric PHEO/PGL p...

    journal_title:Journal of cancer research and clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s00432-020-03138-5

    authors: Jochmanova I,Abcede AMT,Guerrero RJS,Malong CLP,Wesley R,Huynh T,Gonzales MK,Wolf KI,Jha A,Knue M,Prodanov T,Nilubol N,Mercado-Asis LB,Stratakis CA,Pacak K

    更新日期:2020-04-01 00:00:00

  • Combination of weekly streptozocin and oral S-1 treatment for patients of unresectable or metastatic pancreatic neuroendocrine neoplasms.

    abstract:BACKGROUND:Streptozocin (STZ) administration with or without other cytotoxic drugs remains a crucial chemotherapy for patients with advanced pancreatic neuroendocrine neoplasms (Pan-NENs). However, the therapeutic effects of combination treatment with weekly STZ and oral S-1 therapy (STS1) remain unknown. Therefore, th...

    journal_title:Journal of cancer research and clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s00432-019-03109-5

    authors: Ono H,Kudo A,Akahoshi K,Ogura T,Ogawa K,Ban D,Tanaka S,Tanabe M

    更新日期:2020-03-01 00:00:00

  • The PI3K pathway impacts stem gene expression in a set of glioblastoma cell lines.

    abstract:BACKGROUND:The PI3K pathway controls diverse cellular processes including growth, survival, metabolism, and apoptosis. Nuclear FOXO factors were observed in cancers that harbor constitutively active PI3K pathway output and stem signatures. FOXO1 and FOXO3 were previously published to induce stem genes such as OCT4 in e...

    journal_title:Journal of cancer research and clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s00432-020-03133-w

    authors: Martinez E,Vazquez N,Lopez A,Fanniel V,Sanchez L,Marks R,Hinojosa L,Cuello V,Cuevas M,Rodriguez A,Tomson C,Salinas A,Abad M,Holguin M,Garza N,Arenas A,Abraham K,Maldonado L,Rojas V,Basdeo A,Schuenzel E,Persans M

    更新日期:2020-03-01 00:00:00

  • A high serum-free fatty acid level is associated with cancer.

    abstract:PURPOSE:The objectives of this work were to investigate whether the serum-free fatty acid (FFA) level is meaningful in cancer patients and its role in cancer diagnosis. METHODS:A total of 2206 patients were divided into a cancer group (n = 1019) and a noncancer group (n = 1187). Age, sex, body mass index (BMI), and se...

    journal_title:Journal of cancer research and clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s00432-019-03095-8

    authors: Zhang L,Han L,He J,Lv J,Pan R,Lv T

    更新日期:2020-03-01 00:00:00

  • Crosstalk of estrogen receptors and Wnt/β-catenin signaling in endometrial cancer.

    abstract:PURPOSE:To investigate the interaction between Wnt/β-catenin and estrogen signaling pathways in endometrial cancer (EC). METHODS:119 women were involved in this study, including 65 women with histologically confirmed EC and 54 healthy women as a control group. Serum protein levels of Dkk1 were measured using ELISA. Pr...

    journal_title:Journal of cancer research and clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s00432-019-03114-8

    authors: Kasoha M,Dernektsi C,Seibold A,Bohle RM,Takacs Z,Ioan-Iulian I,Solomayer EF,Juhasz-Böss I

    更新日期:2020-02-01 00:00:00

  • DNA methylation-based profiling of uterine neoplasms: a novel tool to improve gynecologic cancer diagnostics.

    abstract:PURPOSE:Uterine neoplasms comprise a broad spectrum of lesions, some of which may pose a diagnostic challenge even to experienced pathologists. Recently, genome-wide DNA methylation-based classification of central nervous system tumors has been shown to increase diagnostic precision in clinical practice when combined w...

    journal_title:Journal of cancer research and clinical oncology

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00432-019-03093-w

    authors: Kommoss FKF,Stichel D,Schrimpf D,Kriegsmann M,Tessier-Cloutier B,Talhouk A,McAlpine JN,Chang KTE,Sturm D,Pfister SM,Romero-Pérez L,Kirchner T,Grünewald TGP,Buslei R,Sinn HP,Mechtersheimer G,Schirmacher P,Schmidt D,Leh

    更新日期:2020-01-01 00:00:00

  • Microwave ablation as local consolidative therapy for patients with extracranial oligometastatic EGFR-mutant non-small cell lung cancer without progression after first-line EGFR-TKIs treatment.

    abstract:OBJECTIVES:Evidence from multiple clinical trials showed that local consolidative therapy (LCT) improved survival in oligometastatic non-small cell lung cancer (NSCLC) patients. In the present study, we aim to explore the potential role of microwave ablation (MWA) as LCT for epidermal growth factor receptor (EGFR)-muta...

    journal_title:Journal of cancer research and clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s00432-019-03043-6

    authors: Ni Y,Ye X,Yang X,Huang G,Li W,Wang J,Han X,Wei Z,Meng M

    更新日期:2020-01-01 00:00:00

  • The age-adjusted Charlson comorbidity index as a predictor of overall survival of surgically treated non-metastatic clear cell renal cell carcinoma.

    abstract:PURPOSE:No study has evaluated the prognostic impact of the age-adjusted Charlson comorbidity index (AACI) in those with renal cell carcinoma (RCC). This study aimed to evaluate the utility of the AACI for predicting long-term survival in patients with surgically treated non-metastatic clear cell RCC (ccRCC). METHODS:...

    journal_title:Journal of cancer research and clinical oncology

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00432-019-03042-7

    authors: Kang HW,Kim SM,Kim WT,Yun SJ,Lee SC,Kim WJ,Hwang EC,Kang SH,Hong SH,Chung J,Kwon TG,Kim HH,Kwak C,Byun SS,Kim YJ,KORCC (KOrean Renal Cell Carcinoma) Group.

    更新日期:2020-01-01 00:00:00

  • Evolving the pulmonary nodules diagnosis from classical approaches to deep learning-aided decision support: three decades' development course and future prospect.

    abstract:PURPOSE:Lung cancer is the commonest cause of cancer deaths worldwide, and its mortality can be reduced significantly by performing early diagnosis and screening. Since the 1960s, driven by the pressing needs to accurately and effectively interpret the massive volume of chest images generated daily, computer-assisted d...

    journal_title:Journal of cancer research and clinical oncology

    pub_type: 杂志文章,评审

    doi:10.1007/s00432-019-03098-5

    authors: Liu B,Chi W,Li X,Li P,Liang W,Liu H,Wang W,He J

    更新日期:2020-01-01 00:00:00

  • Tumor-infiltrating lymphocytes and CD8+ T cells predict survival of triple-negative breast cancer.

    abstract:PURPOSE:Tumor inflammatory response was evaluated as a prognostic feature in triple-negative breast cancer (TNBC) and compared with the clinical prognosticators of breast cancer and selected biomarkers of cancer cell proliferation. METHODS:TNBC patients (n = 179) with complete clinical data and up to 18-year follow-up...

    journal_title:Journal of cancer research and clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s00432-019-03036-5

    authors: Vihervuori H,Autere TA,Repo H,Kurki S,Kallio L,Lintunen MM,Talvinen K,Kronqvist P

    更新日期:2019-12-01 00:00:00

  • Radiomics for diagnosis of dual-phenotype hepatocellular carcinoma using Gd-EOB-DTPA-enhanced MRI and patient prognosis.

    abstract:PURPOSE:To describe the clinical characteristics and outcomes of patients with dual-phenotype hepatocellular carcinoma (DPHCC) and investigate the use of radiomics to establish an image-based signature for preoperative differential diagnosis. METHODS:This study included 50 patients with a postoperative pathological di...

    journal_title:Journal of cancer research and clinical oncology

    pub_type: 杂志文章

    doi:10.1007/s00432-019-03062-3

    authors: Huang X,Long L,Wei J,Li Y,Xia Y,Zuo P,Chai X

    更新日期:2019-12-01 00:00:00

  • Therapeutic outcome and prognostic factors in sinonasal rhabdomyosarcoma: a single-institution case series.

    abstract:BACKGROUND:The purpose of this study was to explore the demographics, multimodality therapeutic outcomes*** and prognostic factors in sinonasal rhabdomyosarcoma (SNRMS). METHODS:We conducted a retrospective analysis of 40 patients who underwent treatment of SNRMS from March 2007 to March 2018. The Kaplan-Meier method ...

    journal_title:Journal of cancer research and clinical oncology

    pub_type: 临床试验,杂志文章

    doi:10.1007/s00432-019-03009-8

    authors: Li W,Lu H,Wang D

    更新日期:2019-11-01 00:00:00

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