Abstract:
:A seroepidemiological survey of bancroftian filariasis was carried out in 2 townships in Sri Lanka with the objectives of determining the microfilaraemia rates, dependence on age and sex, susceptibility to re-infection, effect of diethylcarbamazine therapy on serum antibodies to microfilarial surface antigens, and the predictive value of the indirect fluorescent antibody test. The mean microfilaraemia rate was 5.4%. Microfilaraemia was not sex-dependent but a marginally elevated incidence was seen in the 6-35 year age groups. In up to 58% of the microfilaraemic patients who had been treated for microfilaraemia previously, a second phase of microfilaraemia was seen 2-7 years after treatment. This was unlikely to have been due to incomplete parasite elimination. Antibodies to microfilarial surface were found in 24-35% of microfilaraemic patients and in 14-63% of amicrofilaraemic symptomatic subjects. Serum anti-microfilarial surface antibody levels did not alter with chemotherapy with diethylcarbamazine citrate. The findings of follow-up investigations of microfilaraemic subjects were compatible with the notion that microfilaraemia does not necessarily lead to clinical disease.
journal_name
Trans R Soc Trop Med Hygauthors
Dissanayake Sdoi
10.1016/0035-9203(89)90511-7subject
Has Abstractpub_date
1989-05-01 00:00:00pages
384-8issue
3eissn
0035-9203issn
1878-3503journal_volume
83pub_type
杂志文章abstract::Night blood surveys for filariasis were carried out in two camps of repatriates from Bangladesh. The sample consisted of 1,101 Biharis above one year of age of whom 9.0% were found infected with Wuchereria bancrofti. The infection rate was significantly higher in males (10.2%) than in females (6.7%). Of the three mosq...
journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type: 杂志文章
doi:10.1016/0035-9203(81)90435-1
更新日期:1981-01-01 00:00:00
abstract::The seroprevalence of toxocariasis was investigated in 1997/98 in 1009 schoolchildren (aged 5-12 years) throughout Trinidad. Infection, as measured by titre, was found to be high compared to values obtained from children in other countries. Using an excretory-secretory antigen and performing an ELISA test, it was foun...
journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type: 杂志文章
doi:10.1016/s0035-9203(02)90281-6
更新日期:2002-03-01 00:00:00
abstract::The epidemiological coexistence of schistosomiasis and malaria is frequently observed in developing countries. Co-infection with malaria in children could influence the development of acquired immunity associated with the resistance or the pathology of schistosomiasis. In the present study, performed during May to Jun...
journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type: 杂志文章
doi:10.1016/s0035-9203(03)90170-2
更新日期:2003-05-01 00:00:00
abstract::Antimicrobial resistance is threatening to undermine many of the health care improvements achieved in the tropics in the past 2 decades. While only limited data are available, there is evidence from most tropical areas of the spread of resistant bacterial strains in diseases from typhoid and bacillary dysentery to tub...
journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type: 杂志文章,评审
doi:10.1016/s0035-9203(01)90134-8
更新日期:2001-03-01 00:00:00
abstract:BACKGROUND:Cryptosporidium spp. are enteric parasites that infect humans and animals. In immunocompromised patients infection can be fatal. This study was conducted to identify sub-populations of Cryptosporidium hominis and C. parvum isolates from HIV-seropositive patients in Equatorial Guinea. METHODS:In a previous s...
journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type: 杂志文章,多中心研究
doi:10.1093/trstmh/tru108
更新日期:2014-09-01 00:00:00
abstract::We describe here a method, potentially suitable for field applications, for semi-quantitative detection of Mycobacterium leprae antigens in skin scrapings, which are taken normally for smear microscopy. Thirty acid-fast bacilli-negative paucibacillary (PB) leprosy patients comprised the main study group; eight acid-fa...
journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type: 杂志文章
doi:10.1016/j.trstmh.2007.02.026
更新日期:2007-07-01 00:00:00
abstract::An outbreak of Ross River virus infection (epidemic polyarthritis), which occurred in American Samoa between August 1979 and January 1980, is described. On the basis of a serological survey performed near the end of the epidemic, it is estimated that at least 13,500 people were infected. Ross River virus was isolated ...
journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type: 杂志文章
doi:10.1016/0035-9203(81)90112-7
更新日期:1981-01-01 00:00:00
abstract:BACKGROUND:Rio de Janeiro (RJ) has been of major importance for the epidemiology of dengue viruses (DENVs) in Brazil. After the DENV 1-4 introductions in 1986, 1990, 2000 and 2011, respectively, the state has suffered explosive epidemics. We aimed to describe laboratorial, epidemiological and clinical aspects due to th...
journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type: 杂志文章
doi:10.1093/trstmh/trv006
更新日期:2015-04-01 00:00:00
abstract::963 sera from contacts, persons from various localities, and blood donors were examined with a commercially produced kit for micro-immunofluorescence for the presence of antibodies to Rickettsia conorii. 10.6% of sera were serologically positive. The higher rates of positivity were observed in sera of contacts (19%) a...
journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type: 杂志文章
doi:10.1016/0035-9203(84)90163-9
更新日期:1984-01-01 00:00:00
abstract::Three apparently immunocompetent patients died in the intensive care unit at Loni Hospital, Ahmednagar, Maharashtra, India, between 2001 and 2006 due to multiorgan failure and Strongyloides stercoralis septicaemia following a short course of corticosteroid (prednisolone) therapy of 6-17 days for peripheral blood eosin...
journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type: 杂志文章
doi:10.1016/j.trstmh.2007.05.021
更新日期:2007-11-01 00:00:00
abstract::Eleven cases of alveolar echinococcosis (Echinococcus multilocularis infection) with non-resectable lesions but treated with albendazole for 17 to 69 months were followed-up clinically and serologically for 4.5-11.5 years. Based on the clinical outcome and computerized tomography (CT) scanning, they were divided into ...
journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type: 杂志文章
doi:10.1016/s0035-9203(97)90291-1
更新日期:1997-07-01 00:00:00
abstract:OBJECTIVE:To present the long-term outcome of multidrug-resistant tuberculosis (MDR TB) patients. METHODS:An observational study of 291 MDR TB cases that were diagnosed from 1990 to 2011 at the Fukujuji Hospital in Japan. RESULTS:The frequency of relapse after cure was 3/168 (1.8%) during a mean follow-up of 4.4 year...
journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type: 杂志文章
doi:10.1093/trstmh/tru080
更新日期:2014-09-01 00:00:00
abstract::The liver fluke Opisthorchis felineus is a member of the triad of epidemiologically important liver fluke species belonging to the family Opisthorchiidae and the major agent causing opisthorchiasis over a vast territory, covering Russia, Kazakhstan and several European countries. The similarity between the diseases ca...
journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type: 杂志文章,评审
doi:10.1093/trstmh/trv085
更新日期:2016-01-01 00:00:00
abstract::There is a need for a specific, sensitive, and practical diagnostic test to monitor onchocerciasis elimination campaigns. In April 2001, an enzyme-linked immunosorbent assay (ELISA) using 3 recombinant antigens and a rapid-format antibody card test (immunochromatographic test; ICT) using an individual antigen were com...
journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type: 杂志文章
doi:10.1016/s0035-9203(03)80018-4
更新日期:2003-09-01 00:00:00
abstract::Plasmodia infect the liver for about 7 days before subsequently infecting the blood. Present prophylaxis against Plasmodium falciparum malaria employs agents that primarily kill blood stages and must be continued for 28 days after the last exposure. Atovaquone-proguanil (Malarone) is a new antimalarial agent that is l...
journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0035-9203(01)90206-8
更新日期:2001-07-01 00:00:00
abstract:BACKGROUND:We aimed to estimate and compare the ability of clinical tools for dengue diagnosis in a pediatric population. METHODS:We prospectively evaluated episodes of acute febrile syndrome identified during the follow-up of a population-based cohort of children and adolescents residing in a dengue endemic city. We ...
journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type: 杂志文章
doi:10.1093/trstmh/try135
更新日期:2019-04-01 00:00:00
abstract::To help to elucidate the changes induced by Trypanosoma brucei gambiense in the central nervous system (CNS) in advanced sleeping sickness patients, levels of interleukin-1 (IL-1) and prostaglandins D2 (PGD2) and E2 (PGE2) were measured by radioimmunoassay in the cerebrospinal fluid (CSF) from 24 patients diagnosed on...
journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type: 杂志文章
doi:10.1016/0035-9203(90)90085-s
更新日期:1990-11-01 00:00:00
abstract::In order to estimate the importance as a public health problem of skin diseases, we investigated the prevalence and severity of skin diseases in a representative sample of children in Mali. 1817 children were randomly selected in 30 clusters by probability-proportional-to-size sampling in Koulikoro region. The mean pr...
journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type: 杂志文章
doi:10.1016/0035-9203(95)90068-3
更新日期:1995-09-01 00:00:00
abstract::The activity of bacitracin in vitro against Giardia intestinalis, Trichomonas vaginalis and Tritrichomonas foetus was enhanced 5-10 times by equimolar concentrations of zinc. Bacitracin and bacitracin zinc activity was tolerant to either aerobic or anaerobic culture conditions and equally effective against T. vaginali...
journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type: 杂志文章
doi:10.1016/0035-9203(94)90239-9
更新日期:1994-11-01 00:00:00
abstract::Twenty-one Entamoeba histolytica isolates from a range of geographical locations and representing 3 different zymodemes were tested under xenic anaerobic conditions for their sensitivities to bacitracin and bactracin zinc. Isolates were over 13 times more sensitive to bacitracin zinc than to bacitracin. Our results in...
journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type: 杂志文章
doi:10.1016/0035-9203(94)90519-3
更新日期:1994-01-01 00:00:00
abstract::There are few reports of parasitic disease prevalence in the Dominican Republic. The most recent study was that by Mackie et al. (1951). Examination of purged specimens from individuals employed by two sugar plantations demonstrated generally high prevalences of a number of helminths and protozoans. We report here the...
journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type: 杂志文章
doi:10.1016/0035-9203(81)90196-6
更新日期:1981-01-01 00:00:00
abstract::A study was carried out to assess the patterns of resistance and occurrence of DHFR/DHPS genotypes of Plasmodium falciparum prior to the adoption of sulfadoxine-pyrimethamine (SP) as first-line treatment for uncomplicated malaria in Tanzania. Children under five years (n = 117) with clinical, uncomplicated malaria wer...
journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.trstmh.2003.10.010
更新日期:2004-06-01 00:00:00
abstract:BACKGROUND:Achromobacter xylosoxidans is described as being resistant to antiseptics and disinfectants. We studied in vitro the ability of five strains to survive and grow in such solutions, with and without starvation. METHODS:Bacterial suspensions in rich media and in distilled water were inoculated into eight antis...
journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type: 杂志文章
doi:10.1093/trstmh/trz016
更新日期:2019-06-01 00:00:00
abstract::Using two serological techniques, eight Nigerian West Nile virus isolates were investigated to determine antigenic relationships among them, and to find out if these virus isolates were related to West Nile virus strains from the different zoogeographic areas of the world. One virus differed significantly from the sev...
journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type: 杂志文章
doi:10.1016/0035-9203(76)90175-9
更新日期:1976-01-01 00:00:00
abstract::A large epidemic of urban yellow fever occurred in April and May 1987 in Oyo State, western Nigeria. The principal vector was Aedes aegypti, breeding in domestic water containers. The 1987 outbreak followed an epidemic of sylvatic yellow fever in eastern Nigeria the previous year, and probably resulted from introducti...
journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type: 杂志文章
doi:10.1016/0035-9203(89)90518-x
更新日期:1989-05-01 00:00:00
abstract::Sleeping arrangements under long-lasting impregnated nets (LLIN) were recorded in 2467 households during the low malaria transmission season (May-June 2007) and the same families were followed up during the high malaria transmission season (December 2007-January 2008) in two malaria-endemic areas of Sri Lanka. Approxi...
journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type: 杂志文章
doi:10.1016/j.trstmh.2008.10.018
更新日期:2009-12-01 00:00:00
abstract::Lysophospholipid analogues (LPAs) comprise a class of metabolically stable compounds that have been developed as anticancer agents for over two decades, but which have also potent and selective antiparasitic activity, particularly against trypanosomatid parasites such as Leishmania and Trypanosoma cruzi, both in vitro...
journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type: 杂志文章,评审
doi:10.1016/j.trstmh.2006.03.010
更新日期:2006-12-01 00:00:00
abstract::A survey for Schistosoma intercalatum conducted in Kinshasa, Zaire, in September 1994 revealed a prevalence of 3.6% (n = 167). Three isolates of schistosomes were made by exposing Bulinus wrighti to miracidia hatched from eggs collected from 2 infected children. Characterization of the isolates by biochemical (isoenzy...
journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type: 杂志文章
doi:10.1016/s0035-9203(97)90068-7
更新日期:1997-05-01 00:00:00
abstract::The impact of concomitant human immunodeficiency virus (HIV) infection on the antibody response of onchocerciasis patients to Onchocerca volvulus antigens (OvAg) was studied by Western blotting and enzyme linked immunosorbent assay (ELISA). Immunoglobulin G (IgG) antibodies in sera from 45 HIV-sero-positive O. volvulu...
journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type: 杂志文章
doi:10.1016/s0035-9203(96)90488-5
更新日期:1996-01-01 00:00:00
abstract::We report two cases of people from different states in India who developed polyneuropathy following intake of mefloquine for treatment of malaria. To the best of our knowledge this has not been reported before. ...
journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type: 杂志文章
doi:10.1016/j.trstmh.2005.08.006
更新日期:2006-06-01 00:00:00