Long term outcome of multidrug-resistant TB patients in Fukujuji Hospital in Japan.

Abstract:

OBJECTIVE:To present the long-term outcome of multidrug-resistant tuberculosis (MDR TB) patients. METHODS:An observational study of 291 MDR TB cases that were diagnosed from 1990 to 2011 at the Fukujuji Hospital in Japan. RESULTS:The frequency of relapse after cure was 3/168 (1.8%) during a mean follow-up of 4.4 years. Among 16 failure cases, eight patients were negative in later years. One case among the nine lost-to-follow-up patients with culture conversion returned 1.5 years later with positive culture. CONCLUSIONS:Chronic-positive patients remain positive for years and require observation. Lost to follow-up cases may relapse.

authors

Yoshiyama T,Morimoto K,Okumura M,Sasaki Y,Ogata H,Shiraishi Y,Kudou S

doi

10.1093/trstmh/tru080

subject

Has Abstract

pub_date

2014-09-01 00:00:00

pages

589-90

issue

9

eissn

0035-9203

issn

1878-3503

pii

tru080

journal_volume

108

pub_type

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