Chemotherapy of Entamoeba histolytica: studies in vitro with bacitracin and its zinc salt.

Abstract:

:Twenty-one Entamoeba histolytica isolates from a range of geographical locations and representing 3 different zymodemes were tested under xenic anaerobic conditions for their sensitivities to bacitracin and bactracin zinc. Isolates were over 13 times more sensitive to bacitracin zinc than to bacitracin. Our results indicate that bacitracin zinc may form the basis of an alternative non-toxic treatment of luminal amoebiasis.

authors

Andrews BJ,Bjorvatn B

doi

10.1016/0035-9203(94)90519-3

subject

Has Abstract

pub_date

1994-01-01 00:00:00

pages

98-100

issue

1

eissn

0035-9203

issn

1878-3503

journal_volume

88

pub_type

杂志文章
  • Serological differentiation between past and present infection in hepatic amoebiasis.

    abstract::The indirect fluorescent antibody (IFA) test and the amoebic gel diffusion (AGD) test were assessed as tools for differentiating between past and present infection in invasive amoebiasis; in the case of the IFA test the Entamoeba histolytica-specific IgG and IgM were monitored. In a pilot study in which sera from 56 p...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/0035-9203(84)90115-9

    authors: Jackson TF,Anderson CB,Simjee AE

    更新日期:1984-01-01 00:00:00

  • Application of the avidin-biotin immunohistochemical method for the diagnosis of alveolar hydatid disease from tissue sections.

    abstract::The avidin-biotin immunohistochemical (ABC) method was applied to the diagnosis of alveolar hydatid disease in patients from the hyperendemic region of western Alaska. The test was specific for larval cestodes of the genus Echinococcus, and exhibited high sensitivity. A negative reaction was obtained in all cases in w...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/0035-9203(88)90219-2

    authors: Condon J,Rausch RL,Wilson JF

    更新日期:1988-01-01 00:00:00

  • Are health education interventions effective for the control and prevention of urogenital schistosomiasis in sub-Saharan Africa? A systematic review.

    abstract::An estimated 129 million people are infected with urogenital schistosomiasis in sub-Saharan Africa. Current control recommendations endorse mass administration of praziquantel. Health education is an important component of effective schistosomiasis prevention and control, but there has been limited research on its eff...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章,评审

    doi:10.1093/trstmh/trv008

    authors: Price A,Verma A,Welfare W

    更新日期:2015-04-01 00:00:00

  • Investigation of Nigerians with diffuse radiographic pulmonary shadowing.

    abstract::During a five-year period, 45 Nigerians with radiographic appearances of diffuse pulmonary infiltration with at least six sputum specimens negative on culture for tubercule bacilli were investigated at University College Hospital, Ibadan. The value of pulmonary function studies and open or closed lung biopsy in discov...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/0035-9203(79)90171-8

    authors: Onadeko BO,Sofowora EO,Grillo IA

    更新日期:1979-01-01 00:00:00

  • Rotavirus infection in wild marsupials (Didelphis marsupialis) of the Amazon region.

    abstract::Rotavirus was detected by enzyme-linked immunosorbent assay in faecal specimens collected from two (1.35%) of 148 marsupials trapped in the Amazon jungle environment. The positive samples were both from the "common opossum", Didelphis marsupialis. No infections were found in the stools of 198 animals belonging to othe...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/0035-9203(86)90186-0

    authors: Linhares AC,Pereira JD,Nakauth CM,Gabbay YB

    更新日期:1986-01-01 00:00:00

  • Molecular characterisation of the first New Delhi metallo-β-lactamase 1-producing Acinetobacter baumannii from Tanzania.

    abstract:BACKGROUND:We aimed to characterise the genetic determinants and context of two meropenem-resistant clinical isolates of Acinetobacter baumannii isolated from children hospitalised with bloodstream infections in Dar es Salaam, Tanzania. METHODS:Antimicrobial susceptibility was determined by disc diffusion E-test and b...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1093/trstmh/traa173

    authors: Moyo SJ,Manyahi J,Hubbard ATM,Byrne RL,Masoud NS,Aboud S,Manji K,Blomberg B,Langeland N,Roberts AP

    更新日期:2021-01-27 00:00:00

  • Mortality in a seven-and-a-half-year follow-up of a trial of insecticide-treated mosquito nets in Ghana.

    abstract::A 17% efficacy in preventing all-cause mortality in children aged 6-59 months was previously reported from a cluster-randomized controlled trial of insecticide-treated mosquito nets (ITNs) carried out in the Kassena-Nankana District of northern Ghana from July 1993-June 1995. A follow-up until the end of 2000 found no...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0035-9203(02)90321-4

    authors: Binka FN,Hodgson A,Adjuik M,Smith T

    更新日期:2002-11-01 00:00:00

  • Plasmodium falciparum: administration of anti-sporozoite antibodies during sporogony results in production of sporozoites which are not neutralized by human anti-circumsporozoite protein vaccine sera.

    abstract::Five days after receiving a Plasmodium falciparum NF54 infectious blood meal, Anopheles stephensi mosquitoes were fed rat anti-P, falciparum sporozoite or rabbit anti-R32tet32 antibodies. Sporozoites isolated from salivary glands were tested by the inhibition of sporozoite invasion (ISI) assay using monoclonal antibod...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/0035-9203(89)90481-1

    authors: do Rosario VE,Appiah A,Vaughan JA,Hollingdale MR

    更新日期:1989-05-01 00:00:00

  • Outbreak of Chikungunya fever in Mayotte, Comoros archipelago, 2005-2006.

    abstract::In 2005-2006, a large outbreak of Chikungunya (CHIK) fever occurred on the western Indian Ocean Islands. In Mayotte, concurrent with an enhanced passive case notification system, we carried out two surveys. A seroprevalence survey designed to document recent CHIK infection was conducted on serum samples collected from...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/j.trstmh.2008.02.018

    authors: Sissoko D,Malvy D,Giry C,Delmas G,Paquet C,Gabrie P,Pettinelli F,Sanquer MA,Pierre V

    更新日期:2008-08-01 00:00:00

  • Semi-quantitative detection of Mycobacterium leprae antigens in skin scrapings: suitability as a laboratory aid for field diagnosis of leprosy.

    abstract::We describe here a method, potentially suitable for field applications, for semi-quantitative detection of Mycobacterium leprae antigens in skin scrapings, which are taken normally for smear microscopy. Thirty acid-fast bacilli-negative paucibacillary (PB) leprosy patients comprised the main study group; eight acid-fa...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/j.trstmh.2007.02.026

    authors: Chaturvedi V,Girdhar BK,Sengupta U,Sinha S

    更新日期:2007-07-01 00:00:00

  • Cerebral melioidosis in Singapore: a review of five cases.

    abstract::A variety of neurological manifestations of infection with Burkholderia pseudomallei have been described including cerebral abscesses, which are a well-recognized form of neurological melioidosis. The optimal antibiotic therapy for this condition has not been defined; however, combinations of intravenous antibiotics a...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/s0035-9203(02)90248-8

    authors: Chadwick DR,Ang B,Sitoh YY,Lee CC

    更新日期:2002-01-01 00:00:00

  • Dengue mortality: reassessing the risks in transition countries.

    abstract::In Singapore in 2005 there were 14,209 documented cases of dengue fever, including 25 deaths. The epidemiology of dengue in Singapore is changing, with increasingly severe infection in adults with chronic disease being recognised. We performed a retrospective review of nine adult patients who died of dengue-related il...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/j.trstmh.2008.06.005

    authors: Lahiri M,Fisher D,Tambyah PA

    更新日期:2008-10-01 00:00:00

  • Molecular mechanisms associated with quinolone resistance in Enterobacteriaceae: review and update.

    abstract:BACKGROUND:Quinolones are broad-spectrum antibiotics, which are used for the treatment of different infectious diseases associated with Enterobacteriaceae. During recent decades, the wide use as well as overuse of quinolones against diverse infections has led to the emergence of quinolone-resistant bacterial strains. H...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1093/trstmh/traa041

    authors: Azargun R,Gholizadeh P,Sadeghi V,Hosainzadegan H,Tarhriz V,Memar MY,Pormohammad A,Eyvazi S

    更新日期:2020-10-05 00:00:00

  • Treatment failure of a single high dose of ivermectin for Mansonella perstans filariasis.

    abstract::Infections with Mansonella perstans are common in certain parts of Africa and South America. There is no standard treatment at present. We evaluated the effect of a single high dose of ivermectin (600 micrograms/kg) on microfilaraemia in 7 consecutive patients. No decrease in microfilarial counts could be demonstrated...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/0035-9203(93)90438-v

    authors: Van den Enden E,Van Gompel A,Van der Stuyft P,Vervoort T,Van den Ende J

    更新日期:1993-01-01 00:00:00

  • Health centre versus home presumptive diagnosis of malaria in southern Ghana: implications for home-based care policy.

    abstract::A study was conducted in 1997 to compare the accuracy of presumptive diagnosis of malaria in children aged 1-9 years performed by caretakers of the children to that of health centre staff in 2 ecological zones in southern Ghana. Similar symptoms were reported in the children at home and at the health centre. In the ho...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/s0035-9203(00)90324-9

    authors: Dunyo SK,Afari EA,Koram KA,Ahorlu CK,Abubakar I,Nkrumah FK

    更新日期:2000-05-01 00:00:00

  • Medicinal plants and Malaria: an historical case study of research at the London School of Hygiene and Tropical Medicine in the twentieth century.

    abstract::Interest in medicinal plants has increased in recent years. This article examines the history of medicinal plant research through a case study of the London School of Hygiene and Tropical Medicine (LSHTM) over the past 100 years. Papers published by members of the School and documents in the School archives show a flu...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 历史文章,杂志文章,评审

    doi:10.1016/j.trstmh.2005.11.017

    authors: Taylor S,Berridge V

    更新日期:2006-08-01 00:00:00

  • Kwashiorkor revisited: the pathogenesis of oedema in kwashiorkor and its significance.

    abstract::Cicely Williams, in her original description of kwashiorkor, implied that deficiency of protein in the baby's food could be a main cause of the syndrome. The hallmark of kwashiorkor is oedema. According to the 'classical' theory, an inadequate intake of protein leads to a low plasma albumin concentration, which in tur...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/0035-9203(84)90053-1

    authors: Waterlow JC

    更新日期:1984-01-01 00:00:00

  • Seroreversion in children born to HIV-positive and AIDS mothers from Central West Brazil.

    abstract::The spread of HIV-1 infection among women of childbearing age has led to increasing numbers of children at risk of vertical transmission. This study aimed to assess child outcomes among HIV-positive (n=19) and AIDS (n=22) mothers from Central West Brazil. CD4(+) T-cell counts (FACScount, BD) and viral loads (HIV-1 RT-...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.trstmh.2009.03.016

    authors: Alcântara KC,Pereira GA,Albuquerque M,Stefani MM

    更新日期:2009-06-01 00:00:00

  • Immunoepidemiology of intestinal helminth infections. 4. Immunopathology in trichuriasis: lessons from the mouse model.

    abstract::The severity and consequences of human Trichuris infection vary widely. This may reflect differences in immune response. T. muris is a natural parasite of mice which provides a close, well defined, easily manipulated model for otherwise uninvestigatable aspects of this response. Normal mice reject the parasite in 3 we...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/0035-9203(94)90074-4

    authors: Jenkins D,Wakelin D

    更新日期:1994-05-01 00:00:00

  • Malaria in the Nuba Mountains of Sudan: baseline genotypic resistance and efficacy of the artesunate plus sulfadoxine-pyrimethamine and artesunate plus amodiaquine combinations.

    abstract::Both northern and southern Sudan are deploying artemisinin-based combinations against uncomplicated Plasmodium falciparum malaria (artesunate+sulfadoxine-pyrimethamine [AS+SP] in the north, artesunate+amodiaquine [AS+AQ] in the south). In 2003, we tested the efficacy of 3 day AS+SP and AS+AQ regimens in vivo in the is...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/j.trstmh.2004.10.003

    authors: Hamour S,Melaku Y,Keus K,Wambugu J,Atkin S,Montgomery J,Ford N,Hook C,Checchi F

    更新日期:2005-07-01 00:00:00

  • Utility of recombinant proteins LID-1 and PADL in screening for Mycobacterium leprae infection and leprosy.

    abstract:BACKGROUND:Despite the widespread use of multidrug therapy, leprosy remains an important public health concern in many regions. Detection is generally limited to clinical exam. METHODS:As a two-tiered active case finding strategy, we used the LID-1 (leprosy IDRI diagnostic-1), and PADL (protein advances for the diagno...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1093/trstmh/tru093

    authors: de Souza MM,Netto EM,Nakatani M,Duthie MS

    更新日期:2014-08-01 00:00:00

  • Interstitial pneumonitis in human visceral leishmaniasis.

    abstract::The involvement of the lung in 13 cases of human visceral leishmaniasis was studied. Interstitial pneumonitis with mononuclear cells was found in 76.8% of the cases; 53.8% also had foci of septal fibrosis. Leishmania were seen within macrophages in 3 cases only. However, all 10 interstitial pneumonitis cases showed PA...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/0035-9203(89)90712-8

    authors: Duarte MI,da Matta VL,Corbett CE,Laurenti MD,Chebabo R,Goto H

    更新日期:1989-01-01 00:00:00

  • Experimental and natural infection of Simulium sanchezi by Mansonella ozzardi in the Middle Orinoco region of Venezuela.

    abstract::Experimental and natural infections of Simulium sanchezi by Mansonella ozzardi were studied in the area of Síquita, Territorio Federal Amazonas, Venezuela. The microfilariae developed synchronously in the blackflies, reaching stage L3 in seven to eight days at temperatures between 23 degrees and 27 degrees C. Larvae i...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/0035-9203(85)90226-3

    authors: Yarzábal L,Basáñez MG,Ramírez-Pérez J,Ramírez A,Botto C,Yarzábal A

    更新日期:1985-01-01 00:00:00

  • Comparison of tafenoquine (WR238605) and primaquine in the post-exposure (terminal) prophylaxis of vivax malaria in Australian Defence Force personnel.

    abstract::On return from duty in North Solomons Province (including Bougainville Island), Papua New Guinea, 586 Australian Defence Force personnel received either primaquine (14-d) or tafenoquine (3-d) post-exposure malaria prophylaxis. Within 12 months, 6 of the 214 volunteers receiving primaquine and 7 of 378 receiving tafeno...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/s0035-9203(02)90351-2

    authors: Nasveld P,Kitchener S,Edstein M,Rieckmann K

    更新日期:2002-11-01 00:00:00

  • Plying of speedboats along canals in the city of Kolkata, India, to prevent mosquito breeding.

    abstract:BACKGROUND:Two long sewerage canals in the city of Kolkata, India were heavily infested with larvae, pupae and egg rafts of the mosquito Culex quinquefasciatus. Although the burden of bancroftian filariasis and other diseases transmitted by C. quinquefasciatus in the city is practically zero, the night-biting mosquitoe...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1093/trstmh/trs026

    authors: Biswas D,Mandal B,Biswas B,Banerjee A,Mukherjee TK

    更新日期:2013-03-01 00:00:00

  • Characterisation of DDT, pyrethroid and carbamate resistance in Anopheles funestus from Obuasi, Ghana.

    abstract::Indoor-resting anopheline mosquitoes were collected from Obuasi, Ghana, and were identified morphologically and by PCR as Anopheles funestus Giles. Wild-caught females were induced to lay eggs. Samples of F1 progeny from each family were divided into cohorts and were either exposed to DDT and permethrin or were stored...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/j.trstmh.2008.02.022

    authors: Okoye PN,Brooke BD,Koekemoer LL,Hunt RH,Coetzee M

    更新日期:2008-06-01 00:00:00

  • High tuberculosis incidence among people living with diabetes in Indonesia.

    abstract:BACKGROUND:Data regarding the incidence of tuberculosis (TB) among people living with diabetes (PLWD) in TB-endemic settings are scarce. We examined TB incidence among PLWD in Indonesia who had previously been screened for latent TB infection (LTBI) and TB disease. METHODS:PLWD (≥18 y of age) in an urban setting were ...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1093/trstmh/trz100

    authors: McAllister SM,Koesoemadinata RC,Santoso P,Soetedjo NNM,Kamil A,Permana H,Ruslami R,Critchley JA,van Crevel R,Hill PC,Alisjahbana B

    更新日期:2020-02-07 00:00:00

  • Serological survey of Prospect Hill virus infection in indigenous wild rodents in the USA.

    abstract::We found serological evidence of infection with Prospect Hill virus, a Hantaan-like virus isolated from meadow voles (Microtus pennsylvanicus), in microtine and cricetid rodents trapped in Maryland, West Virginia, Minnesota and California, USA. Fluorescent antibodies were detected in sera from M. pennsylvanicus (74/27...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/0035-9203(87)90275-6

    authors: Yanagihara R,Daum CA,Lee PW,Baek LJ,Amyx HL,Gajdusek DC,Gibbs CJ Jr

    更新日期:1987-01-01 00:00:00

  • Improvement of direct agglutination test (DAT) for laboratory diagnosis of visceral leishmaniasis in Brazil.

    abstract::We previously standardized the direct agglutination test (DAT) to detect anti-Leishmania chagasi promastigote antibodies (DAT-LPC) with good sensitivity and specificity for diagnosing visceral leishmaniasis (VL). In this paper, we present a technical upgrade by introducing some modifications into the antigen preparati...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/j.trstmh.2009.04.007

    authors: Oliveira E,Pedras MJ,de Assis IE,Rabello A

    更新日期:2009-12-01 00:00:00

  • Description of a dermatropic Leishmania close to L. killicki (Rioux, Lanotte & Pratlong 1986) in Algeria.

    abstract::Cutaneous leishmaniasis (CL) is endemic in Algeria where two forms have been previously described, the sporadic form caused by Leishmania infantum in the north and the cutaneous form caused by L. major in central and southern parts of the country. During 2005, a CL outbreak occurred in the province of Ghardaïa, locate...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/j.trstmh.2009.04.013

    authors: Harrat Z,Boubidi SC,Pratlong F,Benikhlef R,Selt B,Dedet JP,Ravel C,Belkaid M

    更新日期:2009-07-01 00:00:00