Abstract:
:Of 218 patients with arterial hypertension, who responded to monotherapy with prazosin (Minipress) during the first 3 months, 178 persons completed the 12-month treatment according to the study protocol. In 9 patients (4.1%) treatment was discontinued because of increase of blood pressure and/or side effects. In the remaining cases patients did not apply for the control examination or the obtained records were incomplete. During all periods of treatment the mean values of systolic and diastolic blood pressure were significantly lower than the corresponding initial values. No significant symptoms of drug tolerance were observed. Mean daily dose of Minipress after 12 months was 5.9 in comparison with 5.6 mg after 3-month therapy. Normal systolic and diastolic pressures at the end of treatment were found in 114 (64%) and 153 (86%) patients, respectively. Full normalization of blood pressure (less than or equal to 140/90) was achieved in 105 (59%) patients. It was found that an important factor determining the antihypertensive effectiveness of Minipress is the initial blood pressure. The inverse correlation between the decrease of systolic pressure and age was found, whereas the age did not affect requiring the drug withdrawal occurred in 27 (14.4%) patients; they were usually the efficacy of Minipress in relation to diastolic blood pressure. Side effects not of moderate intensity and transient character.
journal_name
Kardiol Poljournal_title
Kardiologia polskaauthors
Sznajderman Msubject
Has Abstractpub_date
1989-01-01 00:00:00pages
394-403issue
7-9eissn
0022-9032issn
1897-4279journal_volume
32pub_type
临床试验,杂志文章,多中心研究abstract:BACKGROUND:Kawasaki disease is the most common cause of acquired heart disease in children in developed countries. The incidence of Kawasaki disease varies from 180 in Japan through 20 in United States to 5-8 in the European countries per 100,000 children younger than 5 years of age. AIM:To evaluate cardiac complicati...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:10.5603/KP.a2015.0136
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Arterial hypertension is one of the most common chronic diseases in the western world, affecting more than 25% of the adult population. AIM:The aim of this study was to assess changes in arterial blood pressure (BP) levels in hypertensive patients, after ablation of nerve terminals in renal arteries, using ...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:10.5603/KP.a2017.0100
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Despite advances in cardiovascular medicine, acute coronary syndrome (ACS) is still a major cause of morbidity and mortality worldwide. Synergy between percutaneous coronary intervention with TAXUS™ and Cardiac Surgery (SYNTAX) score is used to determine the extent and complexity of coronary artery disease (...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:10.5603/KP.a2017.0138
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:In patients with chronic stable coronary artery disease (CAD), well‑developed coronary collateral circulation (CCC) is known to reduce long‑term mortality. AIMS:The objective of this study was to determine the relationship of serum calprotectin (S100A8 / S100A9), angiopoietin‑1 (Ang‑1) and angiopoietin‑2 (A...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:10.33963/KP.15023
更新日期:2019-12-19 00:00:00
abstract::The aim of the study was to investigate the effect of a new selective alpha 1-adrenoreceptor blocker doxazosin on blood pressure, serum lipids and lipoproteins in patients with essential hypertension. The study was done in 32 out-patients with mild-to-moderate hypertension (22 men and 10 women, mean age 45.6 +/- 10.1)...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:1993-02-01 00:00:00
abstract:BACKGROUND:Recent data from "real world" registries and some randomised trials concerning the safety and efficacy of drug-eluting stents (DES) in patients with acute ST-elevation myocardial infarction (STEMI) are equivocal. AIM:We sought to compare DES with bare-metal stents (BMS) in STEMI patients treated with primar...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:atrial fibrillation (AF) is difficult to cure and significantly affects quality of life was well as emotional status of patients. AIM:to evaluate quality of life and depression level in patients with various patterns of AF. METHODS:we studied 150 consecutive patients with AF aged 35-83 years, including 61 ...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2010-10-01 00:00:00
abstract:BACKGROUND:Red blood cell distribution width (RDW) is a risk factor related to adverse outcome in patients with heart failure (HF). Less is known about its influence in patients in their first hospitalization by HF. Aims: Our objective was to investigate the prognostic role of RDW in elderly patients firstly hospital...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:10.33963/KP.14818
更新日期:2019-06-25 00:00:00
abstract:BACKGROUND:Altitude illness is a relevant threat to the life and health of participants in mountaineering expeditions. AIM:To determine if impedance cardiography (ICG) can be used in noninvasive monitoring of haemodynamic disturbances at high altitude. METHODS:The study was performed in a group of 13 participants of ...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:It has been shown that early abciximab administration before primary percutaneous coronary intervention (pPCI) for ST-segment elevation myocardial infarction (STEMI) improves efficacy of treatment. However, there are no data on the impact of this strategy on left ventricular (LV) function during long-term fo...
journal_title:Kardiologia polska
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2008-06-01 00:00:00
abstract:BACKGROUND:Percutaneous balloon aortic valvuloplasty (BAV) is an effective method of treatment for aortic stenosis in children. AIMS:This study aimed to assess the long‑term results of BAV in various age groups in the pediatric population. METHODS:This retrospective study included 68 patients (newborns, infants, and ...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:10.33963/KP.15245
更新日期:2020-06-25 00:00:00
abstract::Authors presented intravitally diagnosed and well echocardiographically supplied documentary evidence for a huge thrombus positioned in the left atrioventricular ostium in a 52 years old woman within two months of Björk-Shiley mitral valve replacement because of a mitral valve disease. ...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract:BACKGROUND:Sotalol is a class III antiarrhythmic drug commonly used in various arrhythmia treatments. However, due to its potent potassium channel inhibition, it can prolong the QT interval and lead to malignant arrhythmias. Empagliflozin is an inhibitor of sodium‑glucose cotransporter 2 (SGLT2) and has a positive effe...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:10.33963/KP.15666
更新日期:2021-01-25 00:00:00
abstract:BACKGROUND:Despite wide popularity of football, there is a paucity of scientific evidence explaining the relationship between being a competitive footballer and life expectancy. AIM:The study analyses and compares cause-specific mortality of Polish male elite footballers and the general Polish male population. METHOD...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:10.5603/KP.a2018.0173
更新日期:2018-01-01 00:00:00
abstract::Considerable variation in the use and duration of antiplatelet medications during the perioperative and postoperative care of patients undergoing coronary artery bypass grafting (CABG) reflects the limited number of studies focused directly on these patients as well as the variation in the results reported. In this re...
journal_title:Kardiologia polska
pub_type: 杂志文章,评审
doi:10.5603/KP.a2018.0111
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Recanalisation of chronic total occlusion (CTO) of a coronary artery can be reflected by improvements in various clinical parameters. Revealing increased parasympathetic activity would constitute an additional argument for performing this procedure. AIM:To assess the effect of CTO recanalisation on barorefl...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:10.5603/KP.a2013.0356
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:The aetiology of contrast-induced acute kidney injury (CI-AKI) is not well understood. We hypothesised that the pathophysiology of CI-AKI and impaired coronary reperfusion (IR), observed after invasive treatment of acute myocardial infarction (AMI), could be similar and might be related to platelet count (PC...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:10.5603/KP.a2015.0054
更新日期:2015-01-01 00:00:00
abstract::From the physiological point of view, carotid bodies are mainly responsible for the ventilatory response to hypoxia; however, they also take part in the regulation of sympathetic tone. According to preclinical data, these structures likely contribute to the development and progression of sympathetically mediated disea...
journal_title:Kardiologia polska
pub_type: 杂志文章,评审
doi:10.5603/KP.a2018.0178
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:The ACC/AHA guidelines for management of patients with ST-elevation myocardial infarction (STEMI) have recommended primary PCI (pPCI) as the preferred reperfusion therapy, when it can be performed in a timely fashion, within 90-110 min from the first contact with medical personnel. The impact of treatment de...
journal_title:Kardiologia polska
pub_type: 临床试验,杂志文章
doi:
更新日期:2007-11-01 00:00:00
abstract::Precordial maps of R, S and Q waves were performed in 43 children with congenital and acquired cardiac defects, with cardiomyopathies and also in 55 healthy children. Two subgroups with the left and right ventricular hypertrophies were separated basing on a standard electrocardiogram. Multilead electrocardiogram (M60-...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract:BACKGROUND:Patients with advanced lower limb ischaemia are, at present, mainly treated using revascularisation. AIM:The aim of the study was to investigate whether the dynamics of blood flow in below-the-knee (BTK) arteries assessed by angiography correlate with clinical outcomes after a 12-month follow-up in patients...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:10.5603/KP.a2018.0212
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Desmin plays one of the key roles in cardiomyocytes. The protein protects the integration of the cell and has the following actions: mechanical, structural and regulatory. Observed abnormalities of its activity have been associated with worsening of heart failure (HF). AIM:Evaluation of desmin activity dete...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2007-03-01 00:00:00
abstract::The coronavirus disease 2019 (COVID-19) pandemic affects anticoagulation not only in those infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) but also in most patients who require daily anticoagulant therapy and are facing substantial limitations in medical care these days. Concomitant venous t...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:10.33963/KP.15425
更新日期:2020-06-25 00:00:00
abstract::In 103 hearts with various forms of cardiac muscle hypertrophy the following parameters were estimated: diameter, length, volume, density and number of myocytes, as well as the density of nuclei of myocytes. The values of all histometric parameters correlated well with the LV weight up to 350 g. In heavier hearts thes...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::Chronic thromboembolic pulmonary embolism not preceded by clinical thromboembolic event(s) in a 50 year-old male with a history of three-year dyspnea on exertion was detected. Proximal chronic pulmonary embolism, mean pulmonary artery pressure 32 mm Hg, and pulmonary vascular resistance of 444 dyn x s(-1) x cm(-5) wer...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Obstructive sleep apnoea syndrome (OSAS) is reported to be associated with hypertension, coronary artery disease, atrial fibrillation, and heart failure. Galectin-3 plays an important role in the regulation of inflammation, development of cardiac fibrosis, and remodelling. A significant relationship between ...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:10.5603/KP.a2016.0185
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND AND AIM:In patients with mitral stenosis (MS) percutaneous mitral balloon valvuloplasty (PMBV) is used to im-prove symptoms and prognosis. Although there is some evidence for potential long-term benefits from PMBV in asymptomatic patients with mitral valve area (MVA) between 1.0 and 1.5 cm2, there are no fol...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:10.5603/KP.a2018.0036
更新日期:2018-01-01 00:00:00
abstract::Endothelin is a family of potent vasoconstrictor peptides of vascular endothelial origin. Although it has been proposed that the vasoconstrictor effects of endothelin are produced at the local vascular level, the current study was performed to test the hypothesis that plasma endothelin concentrations are elevated in p...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:1993-03-01 00:00:00
abstract:BACKGROUND:Data from clinical trials suggested that biodegradable-polymer-based drug-eluting stents (DES) might improve long-term clinical outcomes. PROLIM (Balton, Warsaw, Poland) DES is based on a stainless steel platform with a closed cell design releasing sirolimus from biodegradable copolymer (lactic and glycolic ...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:10.5603/KP.a2015.0208
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Permanent atrial fibrillation (AF) is present before operation and persists after surgery in 30-40% of patients undergoing mitral valve surgery. Using the maze procedure, 75-82% of patients can be cured of AF, but the procedure is difficult and long lasting. Percutaneous radiofrequency (RF) ablation has emer...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2008-09-01 00:00:00