[Minipress in the treatment of arterial hypertension in light of results from a multicenter study. II. Results of long-term monotherapy].

Abstract:

:Of 218 patients with arterial hypertension, who responded to monotherapy with prazosin (Minipress) during the first 3 months, 178 persons completed the 12-month treatment according to the study protocol. In 9 patients (4.1%) treatment was discontinued because of increase of blood pressure and/or side effects. In the remaining cases patients did not apply for the control examination or the obtained records were incomplete. During all periods of treatment the mean values of systolic and diastolic blood pressure were significantly lower than the corresponding initial values. No significant symptoms of drug tolerance were observed. Mean daily dose of Minipress after 12 months was 5.9 in comparison with 5.6 mg after 3-month therapy. Normal systolic and diastolic pressures at the end of treatment were found in 114 (64%) and 153 (86%) patients, respectively. Full normalization of blood pressure (less than or equal to 140/90) was achieved in 105 (59%) patients. It was found that an important factor determining the antihypertensive effectiveness of Minipress is the initial blood pressure. The inverse correlation between the decrease of systolic pressure and age was found, whereas the age did not affect requiring the drug withdrawal occurred in 27 (14.4%) patients; they were usually the efficacy of Minipress in relation to diastolic blood pressure. Side effects not of moderate intensity and transient character.

journal_name

Kardiol Pol

journal_title

Kardiologia polska

authors

Sznajderman M

subject

Has Abstract

pub_date

1989-01-01 00:00:00

pages

394-403

issue

7-9

eissn

0022-9032

issn

1897-4279

journal_volume

32

pub_type

临床试验,杂志文章,多中心研究
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    abstract:BACKGROUND:Arterial hypertension is one of the most common chronic diseases in the western world, affecting more than 25% of the adult population. AIM:The aim of this study was to assess changes in arterial blood pressure (BP) levels in hypertensive patients, after ablation of nerve terminals in renal arteries, using ...

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    更新日期:2017-01-01 00:00:00

  • Evaluation of the relationship between renal resistive index and extent and complexity of coronary artery disease in patients with acute coronary syndrome.

    abstract:BACKGROUND:Despite advances in cardiovascular medicine, acute coronary syndrome (ACS) is still a major cause of morbidity and mortality worldwide. Synergy between percutaneous coronary intervention with TAXUS™ and Cardiac Surgery (SYNTAX) score is used to determine the extent and complexity of coronary artery disease (...

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  • Relationship of serum calprotectin, angiopoietin‑1, and angiopoietin‑2 levels with coronary collateral circulation in patients with stable coronary artery disease.

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    pub_type: 杂志文章

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    authors: Demir V,Ede H,Ercan M,Turan Y,Hidayet S,Inandiklioglu N,Erbay AR

    更新日期:2019-12-19 00:00:00

  • [Doxazosin (alpha 1-adrenoreceptor antagonist) used in primary hypertension and it's beneficial effect on lipid metabolism].

    abstract::The aim of the study was to investigate the effect of a new selective alpha 1-adrenoreceptor blocker doxazosin on blood pressure, serum lipids and lipoproteins in patients with essential hypertension. The study was done in 32 out-patients with mild-to-moderate hypertension (22 men and 10 women, mean age 45.6 +/- 10.1)...

    journal_title:Kardiologia polska

    pub_type: 杂志文章

    doi:

    authors: Sznajderman M,Chotkowska E,Peczkowska M,Sawicki M,Janaszek-Sitkowska H,Wiernikowska-Wegorek I,Galewicz A,Cybulska I

    更新日期:1993-02-01 00:00:00

  • Comparison of drug-eluting stents to bare-metal stents in ST-elevation myocardial infarction in long-term follow-up.

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    pub_type: 杂志文章

    doi:

    authors: Kübler P,Jankowska EA,Ferenc M,Ponikowski P,Banasiak W,Reczuch K

    更新日期:2013-01-01 00:00:00

  • Quality of life and depression in patients with different patterns of atrial fibrillation.

    abstract:BACKGROUND:atrial fibrillation (AF) is difficult to cure and significantly affects quality of life was well as emotional status of patients. AIM:to evaluate quality of life and depression level in patients with various patterns of AF. METHODS:we studied 150 consecutive patients with AF aged 35-83 years, including 61 ...

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    pub_type: 杂志文章

    doi:

    authors: Dąbrowski R,Smolis-Bąk E,Kowalik I,Kazimierska B,Wójcicka M,Szwed H

    更新日期:2010-10-01 00:00:00

  • Red blood cell distribution width as a prognostic factor of mortality in elderly patients firstly hospitalized due to heart failure.

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    pub_type: 杂志文章

    doi:10.33963/KP.14818

    authors: Salvatori M,Formiga F,Moreno-Gónzalez R,Chivite D,Migone De Amicis M,Cappellini MD,Corbella X

    更新日期:2019-06-25 00:00:00

  • Impedance cardiography as a tool for haemodynamic monitoring at high altitude: a preliminary study.

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    journal_title:Kardiologia polska

    pub_type: 杂志文章

    doi:

    authors: Krzesiński P,Sadłoń NM,Grudzień KT,Gielerak G,Stańczyk A

    更新日期:2012-01-01 00:00:00

  • Effects of early abciximab administration before primary percutaneous coronary intervention on left ventricular function assessed by cardiac magnetic resonance.

    abstract:BACKGROUND:It has been shown that early abciximab administration before primary percutaneous coronary intervention (pPCI) for ST-segment elevation myocardial infarction (STEMI) improves efficacy of treatment. However, there are no data on the impact of this strategy on left ventricular (LV) function during long-term fo...

    journal_title:Kardiologia polska

    pub_type: 杂志文章,随机对照试验

    doi:

    authors: Rakowski T,Mielecki W,Brzozowska-Czarnek A,Dziewierz A,Siudak Z,Legutko J,Rzeszutko L,Urbanik A,Dubiel JS,Dudek D

    更新日期:2008-06-01 00:00:00

  • Long-term results of percutaneous balloon aortic valvuloplasty in children with aortic stenosis: a single-center experience.

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    pub_type: 杂志文章

    doi:10.33963/KP.15245

    authors: Godlewski K,Werner B

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  • [Giant thrombus of mitral valve prosthesis diagnosed by two-dimensional and Doppler echocardiography and confirmed by autopsy].

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    pub_type: 杂志文章

    doi:

    authors: Porada A,Sobkowicz-Woźniak B,Spikowski J,Wrabec K,Kowalisko A,Grodź J

    更新日期:1989-01-01 00:00:00

  • Empagliflozin significantly attenuates sotalol-induced QTc prolongation in rats.

    abstract:BACKGROUND:Sotalol is a class III antiarrhythmic drug commonly used in various arrhythmia treatments. However, due to its potent potassium channel inhibition, it can prolong the QT interval and lead to malignant arrhythmias. Empagliflozin is an inhibitor of sodium‑glucose cotransporter 2 (SGLT2) and has a positive effe...

    journal_title:Kardiologia polska

    pub_type: 杂志文章

    doi:10.33963/KP.15666

    authors: Özgür Barış V,Dinçsoy B,Gedikli E,Erdemb A

    更新日期:2021-01-25 00:00:00

  • Longevity and cardiovascular mortality of Polish elite football players.

    abstract:BACKGROUND:Despite wide popularity of football, there is a paucity of scientific evidence explaining the relationship between being a competitive footballer and life expectancy. AIM:The study analyses and compares cause-specific mortality of Polish male elite footballers and the general Polish male population. METHOD...

    journal_title:Kardiologia polska

    pub_type: 杂志文章

    doi:10.5603/KP.a2018.0173

    authors: Gajda J,Śmigielski W,Śmigielski J,Pakos E,Drygas W

    更新日期:2018-01-01 00:00:00

  • Antiplatelet therapy for patients undergoing coronary artery bypass surgery.

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    journal_title:Kardiologia polska

    pub_type: 杂志文章,评审

    doi:10.5603/KP.a2018.0111

    authors: DeStephan CM,Schneider DJ

    更新日期:2018-01-01 00:00:00

  • The effect of chronically occluded coronary artery recanalisation on baroreflex sensitivity and left ventricular systolic function.

    abstract:BACKGROUND:Recanalisation of chronic total occlusion (CTO) of a coronary artery can be reflected by improvements in various clinical parameters. Revealing increased parasympathetic activity would constitute an additional argument for performing this procedure. AIM:To assess the effect of CTO recanalisation on barorefl...

    journal_title:Kardiologia polska

    pub_type: 杂志文章

    doi:10.5603/KP.a2013.0356

    authors: Daniłowicz-Szymanowicz L,Pinna GD,Dorniak K,Mincewicz G,Zagożdżon P,Dorniak W,Suchecka J,Raczak G

    更新日期:2014-01-01 00:00:00

  • Platelet count and volume indices in patients with contrast-induced acute kidney injury and acute myocardial infarction treated invasively.

    abstract:BACKGROUND:The aetiology of contrast-induced acute kidney injury (CI-AKI) is not well understood. We hypothesised that the pathophysiology of CI-AKI and impaired coronary reperfusion (IR), observed after invasive treatment of acute myocardial infarction (AMI), could be similar and might be related to platelet count (PC...

    journal_title:Kardiologia polska

    pub_type: 杂志文章

    doi:10.5603/KP.a2015.0054

    authors: Francuz P,Kowalczyk J,Swoboda R,Przybylska-Siedlecka K,Kozieł M,Podolecki T,Świątkowski A,Lenarczyk R,Średniawa B,Kalarus Z

    更新日期:2015-01-01 00:00:00

  • Human carotid bodies as a therapeutic target: new insights from a clinician's perspective.

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    journal_title:Kardiologia polska

    pub_type: 杂志文章,评审

    doi:10.5603/KP.a2018.0178

    authors: Tubek S,Niewiński P,Paleczny B,Langner A,Banasiak W,Ponikowski P

    更新日期:2018-01-01 00:00:00

  • Impact of the time to reperfusion on early outcomes in patients with acute myocardial infarction undergoing primary angioplasty.

    abstract:BACKGROUND:The ACC/AHA guidelines for management of patients with ST-elevation myocardial infarction (STEMI) have recommended primary PCI (pPCI) as the preferred reperfusion therapy, when it can be performed in a timely fashion, within 90-110 min from the first contact with medical personnel. The impact of treatment de...

    journal_title:Kardiologia polska

    pub_type: 临床试验,杂志文章

    doi:

    authors: Trzos E,Kurpesa M,Bednarkiewicz Z,Peruga J,Kasprzak J,Plewka M,Uznańska B,Krzemińska-Pakuła M

    更新日期:2007-11-01 00:00:00

  • [Precordial mapping of R, S and Q waves in healthy children and in those with heart defects and cardiomyopathies].

    abstract::Precordial maps of R, S and Q waves were performed in 43 children with congenital and acquired cardiac defects, with cardiomyopathies and also in 55 healthy children. Two subgroups with the left and right ventricular hypertrophies were separated basing on a standard electrocardiogram. Multilead electrocardiogram (M60-...

    journal_title:Kardiologia polska

    pub_type: 杂志文章

    doi:

    authors: Godlewska-Piórkowska A

    更新日期:1989-01-01 00:00:00

  • Dynamics of below-the-knee arterial blood flow after endovascular revascularisation of peripheral arteries as a potential predictor of clinical outcomes during one-year follow-up.

    abstract:BACKGROUND:Patients with advanced lower limb ischaemia are, at present, mainly treated using revascularisation. AIM:The aim of the study was to investigate whether the dynamics of blood flow in below-the-knee (BTK) arteries assessed by angiography correlate with clinical outcomes after a 12-month follow-up in patients...

    journal_title:Kardiologia polska

    pub_type: 杂志文章

    doi:10.5603/KP.a2018.0212

    authors: Kaczmarczyk P,Krzanowski M,Szybiak E,Maga M,Wachsmann A,Tyrak K,Januszek R,Belowski A,Partyka Ł,Maga P

    更新日期:2019-01-01 00:00:00

  • Evaluation of desmin activity using immunohistochemical and immunofluorescent staining of myocardial biopsies in patients with chronic heart failure. Comparison of the two methods.

    abstract:BACKGROUND:Desmin plays one of the key roles in cardiomyocytes. The protein protects the integration of the cell and has the following actions: mechanical, structural and regulatory. Observed abnormalities of its activity have been associated with worsening of heart failure (HF). AIM:Evaluation of desmin activity dete...

    journal_title:Kardiologia polska

    pub_type: 杂志文章

    doi:

    authors: Pawlak A,Gil RJ,Walczak E,Fidziańska A

    更新日期:2007-03-01 00:00:00

  • Guidance for anticoagulation management in venous thromboembolism during the coronavirus disease 2019 pandemic in Poland: an expert opinion of the Section on Pulmonary Circulation of the Polish Cardiac Society.

    abstract::The coronavirus disease 2019 (COVID-19) pandemic affects anticoagulation not only in those infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) but also in most patients who require daily anticoagulant therapy and are facing substantial limitations in medical care these days. Concomitant venous t...

    journal_title:Kardiologia polska

    pub_type: 杂志文章

    doi:10.33963/KP.15425

    authors: Kosior DA,Undas A,Kopeć G,Hryniewiecki T,Torbicki A,Mularek-Kubzdela T,Windyga J,Pruszczyk P

    更新日期:2020-06-25 00:00:00

  • [Myocardial structure in various forms of hypertrophy. II. Myocyte hypertrophy or hyperplasia? Results of the study].

    abstract::In 103 hearts with various forms of cardiac muscle hypertrophy the following parameters were estimated: diameter, length, volume, density and number of myocytes, as well as the density of nuclei of myocytes. The values of all histometric parameters correlated well with the LV weight up to 350 g. In heavier hearts thes...

    journal_title:Kardiologia polska

    pub_type: 杂志文章

    doi:

    authors: Grajek S,Paradowski S,Zajac M,Kaczmarek E

    更新日期:1990-01-01 00:00:00

  • [Chronic thromboembolic pulmonary embolism not preceded by clinical thromboembolic event - clinical, echocardiographic and haemodynamic course].

    abstract::Chronic thromboembolic pulmonary embolism not preceded by clinical thromboembolic event(s) in a 50 year-old male with a history of three-year dyspnea on exertion was detected. Proximal chronic pulmonary embolism, mean pulmonary artery pressure 32 mm Hg, and pulmonary vascular resistance of 444 dyn x s(-1) x cm(-5) wer...

    journal_title:Kardiologia polska

    pub_type: 杂志文章

    doi:

    authors: Romaszkiewicz R,Lewczuk J,Piszko P,Lenartowska L,Jagas J,Mazij M,Cisowska M,Nowak M,Błaszczyk D

    更新日期:2011-01-01 00:00:00

  • Galectin-3 is associated with coronary plaque burden and obstructive sleep apnoea syndrome severity.

    abstract:BACKGROUND:Obstructive sleep apnoea syndrome (OSAS) is reported to be associated with hypertension, coronary artery disease, atrial fibrillation, and heart failure. Galectin-3 plays an important role in the regulation of inflammation, development of cardiac fibrosis, and remodelling. A significant relationship between ...

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    pub_type: 杂志文章

    doi:10.5603/KP.a2016.0185

    authors: Pusuroglu H,Somuncu U,Bolat I,Akgul O,Ornek V,Yıldırım HA,Akkaya E,Karakurt H,Yıldırım A,Savaş AU

    更新日期:2017-01-01 00:00:00

  • Percutaneous mitral balloon valvuloplasty: beyond classic indications.

    abstract:BACKGROUND AND AIM:In patients with mitral stenosis (MS) percutaneous mitral balloon valvuloplasty (PMBV) is used to im-prove symptoms and prognosis. Although there is some evidence for potential long-term benefits from PMBV in asymptomatic patients with mitral valve area (MVA) between 1.0 and 1.5 cm2, there are no fol...

    journal_title:Kardiologia polska

    pub_type: 杂志文章

    doi:10.5603/KP.a2018.0036

    authors: Tyczyński P,Chmielak Z,Rużyłło W,Demkow M,Dąbrowski M,Konka M,Gajda J,Stokłosa P,Witkowski A

    更新日期:2018-01-01 00:00:00

  • [Level of endothelin increases in chronic congestive heart failure].

    abstract::Endothelin is a family of potent vasoconstrictor peptides of vascular endothelial origin. Although it has been proposed that the vasoconstrictor effects of endothelin are produced at the local vascular level, the current study was performed to test the hypothesis that plasma endothelin concentrations are elevated in p...

    journal_title:Kardiologia polska

    pub_type: 杂志文章

    doi:

    authors: Halawa B

    更新日期:1993-03-01 00:00:00

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    pub_type: 杂志文章

    doi:10.5603/KP.a2015.0208

    authors: Roleder T,Smolka G,Podolecka E,Chudek J,Dworowy S,Żelazowska K,Wojakowski W,Ochała A

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    pub_type: 杂志文章

    doi:

    authors: Myrdko T,Sniezek-Maciejewska M,Rudziński P,Myć J,Lelakowski J,Majewski J

    更新日期:2008-09-01 00:00:00