Abstract:
:From the physiological point of view, carotid bodies are mainly responsible for the ventilatory response to hypoxia; however, they also take part in the regulation of sympathetic tone. According to preclinical data, these structures likely contribute to the development and progression of sympathetically mediated diseases. Moreover, carotid body deactivation in animal models improved blood pressure control in hypertension and reduced mortality in heart failure, along with reducing sympathetic activity. On this basis, two first-in-man studies have been recently performed to investigate the safety and feasibility of such an approach in humans. In this review we summarise the current knowledge regarding the function of carotid bodies, the prevalence of their abnormalities, and the consequences of their excision in human hypertension and heart failure.
journal_name
Kardiol Poljournal_title
Kardiologia polskaauthors
Tubek S,Niewiński P,Paleczny B,Langner A,Banasiak W,Ponikowski Pdoi
10.5603/KP.a2018.0178subject
Has Abstractpub_date
2018-01-01 00:00:00pages
1426-1433issue
10eissn
0022-9032issn
1897-4279pii
VM/OJS/KP/12474journal_volume
76pub_type
杂志文章,评审abstract:BACKGROUND AND AIM:We hypothesised that melatonin may represent a safe somniferous drug for cardiac patients, and assessed the effects of administering 5 mg of melatonin daily before bedtime for 30 days in patients with coronary artery disease (CAD) regarding changes in the nocturnal breathing pattern. METHODS:Sixty p...
journal_title:Kardiologia polska
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2012-01-01 00:00:00
abstract:INTRODUCTION:Systolic dyssynchrony as an indication for cardiac re-synchronization therapy is present in a considerable subset of patients with congestive heart failure undergoing surgical coronary revascularisation. Coronary artery bypass grafting offers an optimal setting for totally epicardial cardiac re-synchroniza...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2007-02-01 00:00:00
abstract:BACKGROUND:The effective antihypertensive therapy is one of the main goals of treatment in metabolic syndrome (MS) because hypertensive patients with MS are of high cardiovascular risk. The impedance cardiography (ICG), as a modern technique of non-invasive haemodynamic monitoring, enables the evaluation of cardiac ind...
journal_title:Kardiologia polska
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Patients with multi-vessel coronary artery disease (CAD) are selected for percutaneous coronary interventions (PCI) or surgical revascularisation. The appropriateness of "ad hoc" PCI of borderline lesions (<70% of lumen diameter) in patients with a multi-vessel CAD has not been proven. However, delayed PCI o...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2004-04-01 00:00:00
abstract::Endothelin is a family of potent vasoconstrictor peptides of vascular endothelial origin. Although it has been proposed that the vasoconstrictor effects of endothelin are produced at the local vascular level, the current study was performed to test the hypothesis that plasma endothelin concentrations are elevated in p...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:1993-03-01 00:00:00
abstract:BACKGROUND:Antiplatelet properties of omega-3 polyunsaturated fatty acids (PUFA) have been demonstrated in patients with coronary artery disease (CAD). It is unknown whether omega-3 PUFA can enhance platelet inhibition on standard aspirin and clopidogrel treatment in the setting of CYP2C19 loss-of-function polymorphism...
journal_title:Kardiologia polska
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2012-01-01 00:00:00
abstract::We present a case of a 61 year-old woman with tachycardia originating close to the His bundle where radiofrequency (RF) ablation may bear potential risk of atrioventricular (AV) block. In this case report we discuss the possibility of a AV nodal reciprocating tachycardia with tendon of Todaro breakthrough. Patient was...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2010-08-01 00:00:00
abstract::Persistent left superior vena cava -- a case report. A case of a 72-year-old female admitted for pacemaker implantation is presented. During the procedure, persistent left superior vena cava was found. Pacemaker was inserted via right subclavicular vein. ...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2004-12-01 00:00:00
abstract::After an initial learning experience in the early 70's, radial artery is now used as the second arterial graft of choice (after both ITAs). The aim of the study was to compare patency rates of venous and arterial grafts--especially radial artery--in mid-term follow up period. 19 patients with stable angina and 11 with...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND:Cardiovascular (CV) diseases are a major cause of death in elderly women. Aerobic training improves component CV risk factors. Long-term, higher-intensity, group-based and home-based exercise training has been shown to improve exer-cise performance. However, it is not clear if short-term, group-based or home...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:10.5603/KP.a2017.0035
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:There are numerous data indicating a significant role of the sympathoadrenal system and the reninangiotensin- aldosterone system in the regulation of blood pressure and the pathogenesis of essential hypertension. However, the genetic background of essential hypertension remains unclear. AIM:To determine the...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2004-11-01 00:00:00
abstract::We presented a very rare case of the fistula to coronary artery during staphylococcal aortic valve endocarditis in a young man. The tranesophageal echocardiography detected vegetation on aortic valve leaflets and large regurgitatin. During transesophageal echocardiography the peri-anular multi-chamber abscess formatio...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2010-05-01 00:00:00
abstract::Lead-dependent infective endocarditis (LDIE) has emerged as a serious complication of electrotherapy in the era of advanced medical technology and is a growing problem due to greater patient longevity, limited electrode life-time, an increasing number of abandoned leads, and subclinical symptoms. We present a case of ...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2011-01-01 00:00:00
abstract::119 hypertensive patients were examined by 24-hour ambulatory blood pressure monitoring (ABPM) and traditional (casual) blood pressure measurements. The echocardiographic examination was also performed. Mean and maximal systolic and diastolic blood pressure values, systolic and diastolic pressure amplitude as well as ...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:1993-04-01 00:00:00
abstract::Following an abbreviated historical review of literature related to angina pectoris spanning the period from olden days to the beginning of the XIX th century, this paper analyses Jan Cenner's doctoral dissertation entitled "Dissertation inauguralis medica de angor pectoris", written in Cracow, Poland in 1820. A conci...
journal_title:Kardiologia polska
pub_type: 传,历史文章,杂志文章
doi:
更新日期:2003-04-01 00:00:00
abstract::A 25-year-old woman, gravida 2, para 1, without any previous medical history was admitted to the hospital because of the signs and symptoms of fetal distress. After a caesarean section the woman developed an acute heart failure. Echocardiography demonstrated massive vegetations attached to aortic and mitral valves wit...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2008-10-01 00:00:00
abstract::It is a popular belief, that marijuana smoking is not harmful to health. Some publications, however, suggest its possible association with mental, respiratory and cardiovascular complications, but not with venous thromboembolism. The authors describe a case of severe pulmonary embolism in a mildly obese, 22 year-old m...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2011-01-01 00:00:00
abstract::In the paper computer aided method is described which can be applied for scenario generation of the health care system for cardiovascular diseases treatment. The real life system is represented in the form of patient flows in the network of diagnostic and therapeutic medical services. The adequate computer system with...
journal_title:Kardiologia polska
pub_type: 杂志文章,评审
doi:
更新日期:1989-01-01 00:00:00
abstract:BACKGROUND:Since flow-mediated dilatation (FMD) is influenced by different factors, its clinical usefulness and validation is widely discussed. AIM:To assess the major factors that determine FMD values in a wide range of subjects with and without cardiovascular (CV) risk factors/diseases (CVRF/CVD). METHODS AND RESUL...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:10.5603/KP.a2013.0316
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Heat shock protein (Hsp) 27 expression in cardiomyocytes increases in response to ischaemia. The extracellular release of Hsp27 from cardiomyocytes is proportional to its intracellular levels. AIM:To assess the influence of significant coronary artery disease (CAD), which by definition results in chronic my...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2009-09-01 00:00:00
abstract::Authors presented the first 3 described in Polish literature patients with primary chylopericardium. 2 of them underwent surgery. Literature review was performed based on presented till now 44 cases with this rare disease. Causes, diagnostics and therapy methods of chylopericardium were discussed especially emphasizin...
journal_title:Kardiologia polska
pub_type: 杂志文章,评审
doi:
更新日期:1989-01-01 00:00:00
abstract::Of adult patients of the Cardiac Defects Clinic, National Institute of Cardiology (in Warsaw) we can distinguish several groups of patients with congenital heart defects among which those who were diagnosed after the age of 18 or those who despite of early and correct diagnosis, not underwent surgery on the childhood ...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND:The prevalence of hypertension and lipid disorders is increased in patients with diabetes. The relationship between cholesterol and blood pressure values has not yet been well established in this group of patients. AIM:To assess the correlation between lipid levels and blood pressure values in patients with...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2006-12-01 00:00:00
abstract:BACKGROUND:Helicobacter pylori (H. pylori) infection is one of the most common chronic infections in humans. While a causative relationship between H. pylori infection and several gastrointestinal disorders has been well established, the association between this condition and the development of atherosclerosis and coro...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2002-12-01 00:00:00
abstract:BACKGROUND:The ACC/AHA guidelines for management of patients with ST-elevation myocardial infarction (STEMI) have recommended primary PCI (pPCI) as the preferred reperfusion therapy, when it can be performed in a timely fashion, within 90-110 min from the first contact with medical personnel. The impact of treatment de...
journal_title:Kardiologia polska
pub_type: 临床试验,杂志文章
doi:
更新日期:2007-11-01 00:00:00
abstract:BACKGROUND:Analysis of pathophysiological mechanisms responsible for vaso-vagal reaction reveals a close relationship between neurocardiogenic syncope and the preceding abnormalities of autonomic nervous system (ANS). Therefore, the interest in the assessment of heart rate variability (HRV) for detecting and establishi...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2002-11-01 00:00:00
abstract:BACKGROUND:Due to the recent rapid increase in the number of patients implanted with pacemakers, cardioverter-defibrillators (ICD), and cardiac resynchronisation therapy devices (CRT), conventional monitoring at specialist clinics is becoming increasingly difficult. The development of technology has enabled remote devi...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:10.5603/KP.a2016.0019
更新日期:2016-01-01 00:00:00
abstract::Different types of disorders, varying in time, concerning atrio-ventricular (AV) conductivity may occur during myocardial infarction (MI). Similarly, angiography may reveal the dynamics within lesions of thrombosis in arteries. A case of 58 year-old man, who suffered from temporal AV block of all degrees, and what is ...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:The lumen diameter (LD) of the extracranial carotid arteries determined by B-mode ultrasound has been provedto be associated with most atherosclerotic risk factors and cardiovascular events. This raises the question as to whether LDmay also predict coronary artery disease. AIM:To elucidate whether LD of the...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:10.5603/KP.2013.0192
更新日期:2013-01-01 00:00:00
abstract::Of 218 patients with arterial hypertension, who responded to monotherapy with prazosin (Minipress) during the first 3 months, 178 persons completed the 12-month treatment according to the study protocol. In 9 patients (4.1%) treatment was discontinued because of increase of blood pressure and/or side effects. In the r...
journal_title:Kardiologia polska
pub_type: 临床试验,杂志文章,多中心研究
doi:
更新日期:1989-01-01 00:00:00