Abstract：
BACKGROUND:Heat shock protein (Hsp) 27 expression in cardiomyocytes increases in response to ischaemia. The extracellular release of Hsp27 from cardiomyocytes is proportional to its intracellular levels. AIM:To assess the influence of significant coronary artery disease (CAD), which by definition results in chronic myocardial ischaemia, on blood serum levels of Hsp27. METHODS:Blood serum levels of Hsp27 in 62 patients with at least 50% lumen diameter narrowing in at least one main epicardial coronary artery on angiography and in 21 controls with normal coronaries were measured. RESULTS:Patients with CAD tended to have higher serum level of Hsp27 than controls [0.463 (0.158-0.809) vs. 0.184 (0.099-0.337) ng/ml, p = 0.084]. Serum Hsp27 level in patients with CAD affecting more than a single vessel was significantly increased [0.529 (0.192-1.004) ng/ml] compared with controls (p = 0.035) and with one artery narrowed [0.276 (0.087-0.549) ng/ml, p = 0.041]. No correlation between Hsp27 serum levels and severity of coronary narrowings assessed by Gensini score was found (r = 0.21, p = 0.11). CONCLUSIONS:Serum level of Hsp27 seems to be a potential marker of myocardial ischaemia caused by advanced 2- or 3-vessel CAD.
journal_name
Kardiol Poljournal_title
Kardiologia polskaauthors
Józefowicz-Okonkwo G,Wierzbowska-Drabik K,Kasielski M,Trzos E,Goraca A,Nowak D,Kasprzak J,Krzemińska-Pakuła Msubject
Has Abstractpub_date
2009-09-01 00:00:00pages
947-52issue
9eissn
0022-9032issn
1897-4279pii
13298journal_volume
67pub_type
杂志文章abstract：:From the physiological point of view, carotid bodies are mainly responsible for the ventilatory response to hypoxia; however, they also take part in the regulation of sympathetic tone. According to preclinical data, these structures likely contribute to the development and progression of sympathetically mediated disea...
journal_title：Kardiologia polska
pub_type： 杂志文章,评审
doi：10.5603/KP.a2018.0178
更新日期：2018-01-01 00:00:00
abstract：:We present a case of a woman who had acute coronary syndrome caused by myocardial bridge. She was treated with percutaneous coronary intervention and stent implantation. Two months after the procedure the patient had myocardial infarction because of subacute thrombosis and during the second intervention another stent ...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2007-06-01 00:00:00
abstract：:A case of a 42-year old man with aortic valve endocarditis with peri-anular multi-chamber abscess formation and fistulous communication between right sinus of Valsalva and right ventricle, is presented. Transthoracic echocardiography revealed abnormal flow through the fistula confirmed at surgery. Intraoperatively the...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2006-06-01 00:00:00
abstract：:Lead-dependent infective endocarditis (LDIE) has emerged as a serious complication of electrotherapy in the era of advanced medical technology and is a growing problem due to greater patient longevity, limited electrode life-time, an increasing number of abandoned leads, and subclinical symptoms. We present a case of ...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2011-01-01 00:00:00
abstract：INTRODUCTION:In patients treated with permanent pacing, the electrode is typically placed in the right ventricular apex (RVA). Published data indicate that such electrode placement leads to an unfavourable ventricular depolarization pattern, while right ventricular outflow tract (RVOT) pacing seems to be more physiolog...
journal_title：Kardiologia polska
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2006-10-01 00:00:00
abstract：:In 17 patients aged 21-61 (mean 32) with WPW syndrome the transoseophageal stimulation was performed before and after intravenous administration of propranolol (0.1 mg/kg b.w.) and atropine (0.02 mg/kg b.w.). Pharmacological blockade of the autonomic nervous system resulted in statistically significant increase of hea...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：BACKGROUND:Data from clinical trials suggested that biodegradable-polymer-based drug-eluting stents (DES) might improve long-term clinical outcomes. PROLIM (Balton, Warsaw, Poland) DES is based on a stainless steel platform with a closed cell design releasing sirolimus from biodegradable copolymer (lactic and glycolic ...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：10.5603/KP.a2015.0208
更新日期：2016-01-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：10.5603/KP.a2015.0054
更新日期：2015-01-01 00:00:00
abstract：:Precordial maps of R, S and Q waves were performed in 43 children with congenital and acquired cardiac defects, with cardiomyopathies and also in 55 healthy children. Two subgroups with the left and right ventricular hypertrophies were separated basing on a standard electrocardiogram. Multilead electrocardiogram (M60-...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:A case of arrhythmogenic right ventricular dysplasia (ARVD) in a 28 year old man is reported. Diagnosis was based on ECG, echocardiographic and scintigraphic findings. Echocardiography and scintigraphy revealed an enlarged right ventricle and normal left ventricle. The abnormalities specific for ARVD were free wall mo...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：BACKGROUND AND AIM:We hypothesised that melatonin may represent a safe somniferous drug for cardiac patients, and assessed the effects of administering 5 mg of melatonin daily before bedtime for 30 days in patients with coronary artery disease (CAD) regarding changes in the nocturnal breathing pattern. METHODS:Sixty p...
journal_title：Kardiologia polska
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2012-01-01 00:00:00
abstract：BACKGROUND AND AIM:The purpose of this study was to determine the role of dominant frequency (DF) and organised index (OI) in outcomes of pulmonary vein (PV) isolation for paroxysmal atrial fibrillation (AF). METHODS:OI and DF of electrograms in coronary vein (CS) during AF were obtained by frequency spectra analysis ...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2012-01-01 00:00:00
abstract：BACKGROUND:Cardiovascular (CV) diseases are a major cause of death in elderly women. Aerobic training improves component CV risk factors. Long-term, higher-intensity, group-based and home-based exercise training has been shown to improve exer-cise performance. However, it is not clear if short-term, group-based or home...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：10.5603/KP.a2017.0035
更新日期：2017-01-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
abstract：:Chest irradiation and chemotherapy may lead to precocious coronary artery disease due to accelerated atherosclerosis or fibrointimal hyperplasia. Three cases of women (43, 50, and 53 years old) without typical risk factors for cardiac disease admitted to hospital due to acute coronary syndrome are described. Two of th...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2008-04-01 00:00:00
abstract：BACKGROUND:Although the current practice guidelines recommend using both heparin and bivalirudin for percutaneous coronary interventions (PCI), the research data are ambiguous. AIM:The aim of the study was to compare the impact of bivalirudin and heparin on major clinical endpoints in PCI patients with particular emph...
journal_title：Kardiologia polska
pub_type： 杂志文章,meta分析
doi：10.5603/KP.a2018.0024
更新日期：2018-01-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 传,历史文章,杂志文章
doi：
更新日期：2003-04-01 00:00:00
abstract：:We present a 46-year-old male patient with complete atrio-ventricular block. A inflammatory etiology was suspected and finally lyme carditis was diagnosed. The conduction abnormalities disappeared with antibiotic treatment and a pacemaker implantation was not needed. Further follow-up of two years was uneventful. ...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：10.5603/KP.2013.0020
更新日期：2013-01-01 00:00:00
abstract：:Infective endocarditis (IE) is an infectious disease, which leads to death when is untreated. In most cases IE is caused by typical bacteria. IE caused by atypical bacteria is rare. In this paper, we describe a female patient with IE caused by Erysipelothrix rhusiopathiae (ER). Due to inflammation and leaflets' damage...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2004-02-01 00:00:00
abstract：:Familial hereditary ventricular hypertrophy (HCM) is classified as a genetically determined disease (autosomal dominant trait) characterized by generalized ventricular hypertrophy, specific heart sounds and echocardiography images, characteristic ECG changes. Sudden death occurs in some cases. Clinical data and labora...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：1993-08-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2010-07-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
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更新日期：2015-01-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
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更新日期：2015-01-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 临床试验,杂志文章
doi：
更新日期：2007-11-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：10.33963/KP.15666
更新日期：2021-01-25 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:Persistent left superior vena cava -- a case report. A case of a 72-year-old female admitted for pacemaker implantation is presented. During the procedure, persistent left superior vena cava was found. Pacemaker was inserted via right subclavicular vein. ...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2004-12-01 00:00:00
abstract：:The clinical and echocardiographic variables related to spontaneous echo contrast were evaluated in a consecutive series of 600 patients undergoing transesophageal echocardiography with a 5-MHz single plane transducer. The spontaneous contrast was observed in 110 patients (18%). It was seen mainly in the atria; in the...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：1993-05-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2003-12-01 00:00:00
